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The map label for this gene is opuCB [H]

Identifier: 222151709

GI number: 222151709

Start: 1583189

End: 1583833

Strand: Direct

Name: opuCB [H]

Synonym: MCCL_1462

Alternate gene names: 222151709

Gene position: 1583189-1583833 (Clockwise)

Preceding gene: 222151708

Following gene: 222151710

Centisome position: 75.31

GC content: 45.27

Gene sequence:

>645_bases
ATGTTAGCATTCTTACAGGAAAACCAGGCAGAACTACTCGAGAAGACATGGGAGCACATCTCCATCTCACTGCTCAGCCT
ACTTGCAGCAATCATCGTTGCAGTGCCGCTCGGTATTGTGCTCACAAAATCCGATAAACTAGCAAAGATTGTACTCTCTA
TAACAAGTGTGTTACAAACCGTGCCTTCGCTGGCAATACTTGCAATGATGATTCCCTTTTTCGGGATAGGTACAGTACCC
GCTGTTATCGCACTGTTTCTCTATGTGCTGCTTCCAATACTCAATAACACTTATCTCGGCATACAGTCTGTCAACAAAGA
TGCACGAGAAGCAGGTCGTGCAATGGGCATGACTCAGAACCAGCTATTACGTATGGTTGAGCTGCCACTTGCAGTTCCAG
TCATTATGAGCGGTATCAGATTATCTGCTGTCTACGCCATCAGTTGGGCGACGCTTGCTTCATATATCGGCGCCGGGGGA
CTTGGAGACTTTATCTTTAATGGGCTCAATCTCTACCAGCCGAAATTGATTATCGTAGGTGCTGTCGTTGTAACATTGCT
CGCACTCGTTACAGATTTCGTATTAGCATATATAGAAAAAATTACGACCCCACGTGGATTAGTTGTGTCGAAGGGGGAAA
AATAA

Upstream 100 bases:

>100_bases
CTTGATAAGCACGATAGACTGCTCGGCGTCATTACTCGTGCCAACTTAGTAGATATCGTCTATGACACTATCTGGGGCGA
AGCGTTAGAGGAGGTATAAT

Downstream 100 bases:

>100_bases
ATGAAGAAATTACTCATACTATTATCCTGTCTACTCGTGCTTAGTGGCTGTGGACAGAACAATCAAAAAGAAACTGTCAA
GATTGCCTCGGTCTATACGA

Product: glycine/betaine ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MLAFLQENQAELLEKTWEHISISLLSLLAAIIVAVPLGIVLTKSDKLAKIVLSITSVLQTVPSLAILAMMIPFFGIGTVP
AVIALFLYVLLPILNNTYLGIQSVNKDAREAGRAMGMTQNQLLRMVELPLAVPVIMSGIRLSAVYAISWATLASYIGAGG
LGDFIFNGLNLYQPKLIIVGAVVVTLLALVTDFVLAYIEKITTPRGLVVSKGEK

Sequences:

>Translated_214_residues
MLAFLQENQAELLEKTWEHISISLLSLLAAIIVAVPLGIVLTKSDKLAKIVLSITSVLQTVPSLAILAMMIPFFGIGTVP
AVIALFLYVLLPILNNTYLGIQSVNKDAREAGRAMGMTQNQLLRMVELPLAVPVIMSGIRLSAVYAISWATLASYIGAGG
LGDFIFNGLNLYQPKLIIVGAVVVTLLALVTDFVLAYIEKITTPRGLVVSKGEK
>Mature_214_residues
MLAFLQENQAELLEKTWEHISISLLSLLAAIIVAVPLGIVLTKSDKLAKIVLSITSVLQTVPSLAILAMMIPFFGIGTVP
AVIALFLYVLLPILNNTYLGIQSVNKDAREAGRAMGMTQNQLLRMVELPLAVPVIMSGIRLSAVYAISWATLASYIGAGG
LGDFIFNGLNLYQPKLIIVGAVVVTLLALVTDFVLAYIEKITTPRGLVVSKGEK

Specific function: Involved in a high affinity multicomponent binding- protein-dependent transport system for choline; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1174

COG function: function code E; ABC-type proline/glycine betaine transport systems, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788449, Length=191, Percent_Identity=38.2198952879581, Blast_Score=117, Evalue=5e-28,
Organism=Escherichia coli, GI1789033, Length=177, Percent_Identity=36.1581920903955, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1788451, Length=191, Percent_Identity=35.0785340314136, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1786564, Length=142, Percent_Identity=30.9859154929577, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI87081802, Length=149, Percent_Identity=30.2013422818792, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 22962; Mature: 22962

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAFLQENQAELLEKTWEHISISLLSLLAAIIVAVPLGIVLTKSDKLAKIVLSITSVLQT
CCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHH
VPSLAILAMMIPFFGIGTVPAVIALFLYVLLPILNNTYLGIQSVNKDAREAGRAMGMTQN
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHCCCCHH
QLLRMVELPLAVPVIMSGIRLSAVYAISWATLASYIGAGGLGDFIFNGLNLYQPKLIIVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCHHHHHH
AVVVTLLALVTDFVLAYIEKITTPRGLVVSKGEK
HHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCC
>Mature Secondary Structure
MLAFLQENQAELLEKTWEHISISLLSLLAAIIVAVPLGIVLTKSDKLAKIVLSITSVLQT
CCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHH
VPSLAILAMMIPFFGIGTVPAVIALFLYVLLPILNNTYLGIQSVNKDAREAGRAMGMTQN
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHCCCCHH
QLLRMVELPLAVPVIMSGIRLSAVYAISWATLASYIGAGGLGDFIFNGLNLYQPKLIIVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCHHHHHH
AVVVTLLALVTDFVLAYIEKITTPRGLVVSKGEK
HHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7592481; 10216873; 9384377 [H]