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The map label for this gene is ctaD [H]

Identifier: 222150983

GI number: 222150983

Start: 794287

End: 796179

Strand: Direct

Name: ctaD [H]

Synonym: MCCL_0733

Alternate gene names: 222150983

Gene position: 794287-796179 (Clockwise)

Preceding gene: 222150982

Following gene: 222150984

Centisome position: 37.78

GC content: 39.99

Gene sequence:

>1893_bases
TTGGCTACACAAAAAAAGCGTGGTTTACTAATGGAGTACTTAACGACAGTAGACCATAAAAAAATTGCAATTCTTTATTT
AATCATGGGTGGATTGTTCTTCGCCATGGGTGGTATCGAAGCGATGATCATTCGTCTTCAGCTTGCAGTTCCTGAAAATG
ATTTCGTCTCTGCGGGATTATTCAATGAAATGATTACGATGCACGGTACTACAATGATTTTCTTGGCAGCAATGCCGTTA
CTGTTTGCATATATGAACGCAACAGTACCGTTACAAATTGGTGCACGTGACGTTGCATTCCCATTCCTAAATGCATTAGG
GTTCTGGTTATTCTTCTTCGGAGGTATATTCTTAAACTTATCTTGGATTTTAGGTGGCGCACCAGATGCAGGCTGGACTT
CGTATGCTTCACTGTCACTTGCATCAGAAGGGCATGGGATTGACTTCTATGCATTAGGTCTACAAATTTCAGGTGCTGGT
ACTTTAATTGCAGGGATTAACTTCCTTGTTACCATTATTAACATGCGTGCGCCTGGTATGACATTTATGCGTATGCCACT
AATGACTTGGACAACATTAGTTGCTTCAGCTTTAATCGTATTCGCATTCCCTCCACTGACTATCGGATTATTCTTACTTA
TTTTCGATAGAATGTTTGGAACAGGATTCTTTGTAGTATCACAAGGTGGTAACACAATTATCTGGGAACACTTATTCTGG
ATTTTCGGTCACCCTGAAGTATATATTTTAGTATTACCAGCTTTCGGTATTTTCTCTGAAATATTTGCAACATTCTCTAG
AAAACGTTTATTCGGTTATTCTGCAATGGTATTTGCAACGGTATTAATCGGTTTCTTAGGATTCATGGTTTGGGCACACC
ACATGTTCACTGTAGGTCTAGGTCCAACAGCGAACGCGATTTTCGCAGTAGCGACAATGGCAATCGCCGTACCAACTGGT
GTGAAGATCTTCAACTGGTTGCTTACTATCTGGGGTGGTAGTATCGAATTTACGACGCCAATGTTATATGCATTAGCATT
CATCCCTTCATTCGTAATGGGTGGTGTTACTGGTGTAATGCAGGCATCAGCACCAGCTGACTATCAGTATCATGATTCAT
ACTTTATCGTAGCGCATTTCCACTACGTAATCGTTGGTGGGGTAGTATTCGCGTTACTTGCAGGGTTGCATTTCTACTGG
CCATTAATGTTCGGTAAGATGTTAAGTGAGAAATTAGGTAAAGTTTCCTTCGTATTATTCTTTATCGGTTTCCATCTAAC
ATTCTTCCTACAACATTTCTTAGGATTAATGGGTATGCCACGTCGTGTATTCACTTACTTACCTGGTCAAGGTTATGACA
CATTTAACTTAATCTCTACTATCGGTGCCTTAACGATGGCCGTAGCAGTCATTATTTTATTGATAAATATTATCTTAACT
ACAGTGAAAGGTCCTAAAGTAGGACGTGACGCTTGGGGCGATGGCCGTACTTTAGAATGGTCATTACCAATCCCAGTACC
ATTCTATAACTTTGCACAAACACCACTTGTGCGTGGATTAGATGCATTTGATCTTGAGAAGAAACAAGGTAATGGTGAAA
TCTTGCCAGCTGAGTCATTAGGTGATGTTCATATGCCAAATAACTCAATCTTACCATTCGTTCAGTCATTAGGATTATTC
GTTGCAGCATTTGGTGCTTTATACTTAGCAGATGGACAAAAATGGGCACTTGATGCAGTTAAAGATTTACCGGTTCAACC
ATGGGCTCCATTTGTATTAGTTCTAGGTTTAGCGATTACAGCAGGAGCAATGATTGCACGTTCAGTAGTTGATGATCACG
GTTATCACATTACTAAAGAAGAGCTTATCGAGTACGAAAGAGGTGTTAAATAA

Upstream 100 bases:

>100_bases
ACAGGTGCTTACAAAGTTTCAGATAGTGAAATTGATGCTCTAGCTAAATACTTAATGGAACGTAAAGTTGAAAAGTAGTA
AATAAAGGGAGGTTACACAT

Downstream 100 bases:

>100_bases
TGGCACATCATGAAGAACAGATGACGGTTGAGAGATGGCCGAGTCATCCTGAGACAGCTTCATTAGAAGGTAAGAACAAA
TTATTAGGATTCTGGATTTT

Product: cytochrome c oxidase subunit I

Products: NA

Alternate protein names: Caa-3605 subunit 1; Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I; Oxidase aa(3) subunit 1 [H]

Number of amino acids: Translated: 630; Mature: 629

Protein sequence:

>630_residues
MATQKKRGLLMEYLTTVDHKKIAILYLIMGGLFFAMGGIEAMIIRLQLAVPENDFVSAGLFNEMITMHGTTMIFLAAMPL
LFAYMNATVPLQIGARDVAFPFLNALGFWLFFFGGIFLNLSWILGGAPDAGWTSYASLSLASEGHGIDFYALGLQISGAG
TLIAGINFLVTIINMRAPGMTFMRMPLMTWTTLVASALIVFAFPPLTIGLFLLIFDRMFGTGFFVVSQGGNTIIWEHLFW
IFGHPEVYILVLPAFGIFSEIFATFSRKRLFGYSAMVFATVLIGFLGFMVWAHHMFTVGLGPTANAIFAVATMAIAVPTG
VKIFNWLLTIWGGSIEFTTPMLYALAFIPSFVMGGVTGVMQASAPADYQYHDSYFIVAHFHYVIVGGVVFALLAGLHFYW
PLMFGKMLSEKLGKVSFVLFFIGFHLTFFLQHFLGLMGMPRRVFTYLPGQGYDTFNLISTIGALTMAVAVIILLINIILT
TVKGPKVGRDAWGDGRTLEWSLPIPVPFYNFAQTPLVRGLDAFDLEKKQGNGEILPAESLGDVHMPNNSILPFVQSLGLF
VAAFGALYLADGQKWALDAVKDLPVQPWAPFVLVLGLAITAGAMIARSVVDDHGYHITKEELIEYERGVK

Sequences:

>Translated_630_residues
MATQKKRGLLMEYLTTVDHKKIAILYLIMGGLFFAMGGIEAMIIRLQLAVPENDFVSAGLFNEMITMHGTTMIFLAAMPL
LFAYMNATVPLQIGARDVAFPFLNALGFWLFFFGGIFLNLSWILGGAPDAGWTSYASLSLASEGHGIDFYALGLQISGAG
TLIAGINFLVTIINMRAPGMTFMRMPLMTWTTLVASALIVFAFPPLTIGLFLLIFDRMFGTGFFVVSQGGNTIIWEHLFW
IFGHPEVYILVLPAFGIFSEIFATFSRKRLFGYSAMVFATVLIGFLGFMVWAHHMFTVGLGPTANAIFAVATMAIAVPTG
VKIFNWLLTIWGGSIEFTTPMLYALAFIPSFVMGGVTGVMQASAPADYQYHDSYFIVAHFHYVIVGGVVFALLAGLHFYW
PLMFGKMLSEKLGKVSFVLFFIGFHLTFFLQHFLGLMGMPRRVFTYLPGQGYDTFNLISTIGALTMAVAVIILLINIILT
TVKGPKVGRDAWGDGRTLEWSLPIPVPFYNFAQTPLVRGLDAFDLEKKQGNGEILPAESLGDVHMPNNSILPFVQSLGLF
VAAFGALYLADGQKWALDAVKDLPVQPWAPFVLVLGLAITAGAMIARSVVDDHGYHITKEELIEYERGVK
>Mature_629_residues
ATQKKRGLLMEYLTTVDHKKIAILYLIMGGLFFAMGGIEAMIIRLQLAVPENDFVSAGLFNEMITMHGTTMIFLAAMPLL
FAYMNATVPLQIGARDVAFPFLNALGFWLFFFGGIFLNLSWILGGAPDAGWTSYASLSLASEGHGIDFYALGLQISGAGT
LIAGINFLVTIINMRAPGMTFMRMPLMTWTTLVASALIVFAFPPLTIGLFLLIFDRMFGTGFFVVSQGGNTIIWEHLFWI
FGHPEVYILVLPAFGIFSEIFATFSRKRLFGYSAMVFATVLIGFLGFMVWAHHMFTVGLGPTANAIFAVATMAIAVPTGV
KIFNWLLTIWGGSIEFTTPMLYALAFIPSFVMGGVTGVMQASAPADYQYHDSYFIVAHFHYVIVGGVVFALLAGLHFYWP
LMFGKMLSEKLGKVSFVLFFIGFHLTFFLQHFLGLMGMPRRVFTYLPGQGYDTFNLISTIGALTMAVAVIILLINIILTT
VKGPKVGRDAWGDGRTLEWSLPIPVPFYNFAQTPLVRGLDAFDLEKKQGNGEILPAESLGDVHMPNNSILPFVQSLGLFV
AAFGALYLADGQKWALDAVKDLPVQPWAPFVLVLGLAITAGAMIARSVVDDHGYHITKEELIEYERGVK

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Co I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=506, Percent_Identity=39.9209486166008, Blast_Score=353, Evalue=2e-97,
Organism=Escherichia coli, GI1786634, Length=568, Percent_Identity=45.9507042253521, Blast_Score=474, Evalue=1e-135,
Organism=Saccharomyces cerevisiae, GI6226519, Length=472, Percent_Identity=42.5847457627119, Blast_Score=368, Evalue=1e-102,
Organism=Saccharomyces cerevisiae, GI6226524, Length=327, Percent_Identity=42.2018348623853, Blast_Score=253, Evalue=5e-68,
Organism=Saccharomyces cerevisiae, GI6226523, Length=249, Percent_Identity=35.3413654618474, Blast_Score=139, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 69273; Mature: 69142

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATQKKRGLLMEYLTTVDHKKIAILYLIMGGLFFAMGGIEAMIIRLQLAVPENDFVSAGL
CCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHEEEEEEEEECCCCCCHHHHH
FNEMITMHGTTMIFLAAMPLLFAYMNATVPLQIGARDVAFPFLNALGFWLFFFGGIFLNL
HHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
SWILGGAPDAGWTSYASLSLASEGHGIDFYALGLQISGAGTLIAGINFLVTIINMRAPGM
HHHCCCCCCCCCHHHHEEEECCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCC
TFMRMPLMTWTTLVASALIVFAFPPLTIGLFLLIFDRMFGTGFFVVSQGGNTIIWEHLFW
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEEECCCCEEEHHHHHH
IFGHPEVYILVLPAFGIFSEIFATFSRKRLFGYSAMVFATVLIGFLGFMVWAHHMFTVGL
HCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GPTANAIFAVATMAIAVPTGVKIFNWLLTIWGGSIEFTTPMLYALAFIPSFVMGGVTGVM
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHCCHHHHH
QASAPADYQYHDSYFIVAHFHYVIVGGVVFALLAGLHFYWPLMFGKMLSEKLGKVSFVLF
HCCCCCCCEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIGFHLTFFLQHFLGLMGMPRRVFTYLPGQGYDTFNLISTIGALTMAVAVIILLINIILT
HHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVKGPKVGRDAWGDGRTLEWSLPIPVPFYNFAQTPLVRGLDAFDLEKKQGNGEILPAESL
HCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHCCCCHHCCCCCCCCCCEECCCCC
GDVHMPNNSILPFVQSLGLFVAAFGALYLADGQKWALDAVKDLPVQPWAPFVLVLGLAIT
CCCCCCCCCHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHH
AGAMIARSVVDDHGYHITKEELIEYERGVK
HHHHHHHHHHHCCCCEECHHHHHHHHCCCC
>Mature Secondary Structure 
ATQKKRGLLMEYLTTVDHKKIAILYLIMGGLFFAMGGIEAMIIRLQLAVPENDFVSAGL
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHEEEEEEEEECCCCCCHHHHH
FNEMITMHGTTMIFLAAMPLLFAYMNATVPLQIGARDVAFPFLNALGFWLFFFGGIFLNL
HHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
SWILGGAPDAGWTSYASLSLASEGHGIDFYALGLQISGAGTLIAGINFLVTIINMRAPGM
HHHCCCCCCCCCHHHHEEEECCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCC
TFMRMPLMTWTTLVASALIVFAFPPLTIGLFLLIFDRMFGTGFFVVSQGGNTIIWEHLFW
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEEECCCCEEEHHHHHH
IFGHPEVYILVLPAFGIFSEIFATFSRKRLFGYSAMVFATVLIGFLGFMVWAHHMFTVGL
HCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GPTANAIFAVATMAIAVPTGVKIFNWLLTIWGGSIEFTTPMLYALAFIPSFVMGGVTGVM
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHCCHHHHH
QASAPADYQYHDSYFIVAHFHYVIVGGVVFALLAGLHFYWPLMFGKMLSEKLGKVSFVLF
HCCCCCCCEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIGFHLTFFLQHFLGLMGMPRRVFTYLPGQGYDTFNLISTIGALTMAVAVIILLINIILT
HHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVKGPKVGRDAWGDGRTLEWSLPIPVPFYNFAQTPLVRGLDAFDLEKKQGNGEILPAESL
HCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHCCCCHHCCCCCCCCCCEECCCCC
GDVHMPNNSILPFVQSLGLFVAAFGALYLADGQKWALDAVKDLPVQPWAPFVLVLGLAIT
CCCCCCCCCHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHH
AGAMIARSVVDDHGYHITKEELIEYERGVK
HHHHHHHHHHHCCCCEECHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1847686; 9384377 [H]