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The map label for this gene is typA [H]

Identifier: 222150975

GI number: 222150975

Start: 783106

End: 784950

Strand: Direct

Name: typA [H]

Synonym: MCCL_0725

Alternate gene names: 222150975

Gene position: 783106-784950 (Clockwise)

Preceding gene: 222150973

Following gene: 222150976

Centisome position: 37.25

GC content: 41.68

Gene sequence:

>1845_bases
ATGACTAAATTAAGAGAAGATGTACGTAATATTGCAATTATAGCCCACGTCGACCATGGGAAAACGACTTTAGTAGATGA
ACTATTAAAGCAATCGGGAACATTTCGTGAGAACGAGCAGGTCGATGAACGTGCAATGGATTCAAATGATATCGAAAGAG
AACGTGGTATCACGATTTTAGCAAAGAATACAGCGATAGACTATAAAGGAACGCGTATCAACATTCTGGATACACCGGGA
CACGCCGATTTCGGTGGAGAAGTGGAACGTATCATGAAAATGGTAGATGGTGTTATTCTTGTTGTTGATGCATACGAAGG
AACAATGCCGCAGACGCGTTTCGTATTGAAGAAAGCGTTAGAACAAAACTTAAAACCAGTTGTTGTAGTCAACAAAATTG
ATAAGCCTTCAGCACGTCCTGAAGAAGTCCTGGATGAGGTTTATGATTTATTCATTGAACTGGAAGCTAATGATGAGCAG
CTTGATTTCCCTGTAGTGTATGCCTCAGCAATCAATGGAACTGCAAGTCTAGATGCAGCGACGCAAGATGAGAACATGCA
GAGCTTATACGAAACAATTATCGATTACATCCCTGCACCAGTTGATAACCGTGAAGAGGATCTACAGTTCCAGGTTGCCT
TACTGGATTACAATGACTATGTTGGTCGTATTGGTATCGGGCGTGTATTCCGTGGAACGATGGAAGTGGGTCAGCAAGTA
TCATTGATCAAATTAGATGGTACAATCAAGAATTTCCGTGTGACGAAGATCTTCGGTTTCTTCGGATTAAAACGTGTTGA
AATCCAAAAAGCATATGCAGGAGATTTAATCGCAGTCTCTGGTATGGAAGATATTAACGTAGGCGAAACTGTGGCGCCAG
TTGACAATCCTGAAGCGTTACCTGTCCTGCGCATCGATGAGCCGACTTTACAGATGACATTCTCTGTAAATAACTCACCA
TTTGCAGGTAAGGAAGGGAAGTTCGTTACAGCGCGTAACATTCAAGACCGTCTTGAATCACAGCTTGAAACAGATGTATC
ATTACGCGTAGAATCTGTAGGACCAGACAGCTGGACTGTATCAGGTCGTGGAGAACTGCATTTATCCATCTTGATCGAGA
ATATGCGTCGTGAAGGCTTCGAACTTCAAGTATCAAAGCCTGAAGTTATCGTAAAAGAAATCGACGGTAAGAAATATGAA
CCGTATGAGCGTGTGCAGATCGATGTACCAGAAGAACATACAGGATCAGTTATAGAATCTCTTGGAGTACGTAAAGGTGA
AATGGTAGATATGGTTAATGGTGGAAACGGTCAGACACGTTTAATCTTTAACGTCCCTGCACGTGGACTAATTGGATACC
GTACTGAATTTATGTCGATGACACGTGGTTACGGTATACTTAACCATACCTTTGATGAATACCGTCCGTTGCTTAAAGGT
CGTATTGGTGGCCGTCGTAATGGTGTCCTTGTATCTATCGATAAAGGGGTAGCAAGTACTTATGCCATCTTAGCGCTTGA
AGACCGTGGTGTAAACTTCATGGAACCAGGGACAGAAGTGTATGAAGGTATGATCGTTGGTGAAAACTCACGTGATAATG
ACTTGACGGTTAACATTACGAAAGTGAAAGCAGCGAACAACATTCGTTCTGCGACAAAAGAACAGACAACAACGATGAAG
AAACCAAGAATCTTAACACTTGAAGAAGCGTTAGAATACTTAAACGATGATGAGCTAGTGGAAGTTACACCAGAGTCTAT
TCGTCTAAGAAAGAAAACATTAGATAAATCTCAACGTGAAAGAGAACAGAAGAAAGCGAAAGCTGCATTACAGGAAGAAG
AATAG

Upstream 100 bases:

>100_bases
TTTGCTTTCTATAAATTCCATGATATATTAATATCGTATTATATGATATAATATCACAGTTACATAAAAACTGTAAGTTG
ATTAAGAAGGGAAAGACCAC

Downstream 100 bases:

>100_bases
GAGTGATTAAATGAACTTTCTTATAGGGAACGTAAGCACGGATCCTGAACAAAGAATGTCATTTCTCGCAAAACTGTTTG
CAGTAGATAAAAATCCAGAA

Product: BipA family GTPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 614; Mature: 613

Protein sequence:

>614_residues
MTKLREDVRNIAIIAHVDHGKTTLVDELLKQSGTFRENEQVDERAMDSNDIERERGITILAKNTAIDYKGTRINILDTPG
HADFGGEVERIMKMVDGVILVVDAYEGTMPQTRFVLKKALEQNLKPVVVVNKIDKPSARPEEVLDEVYDLFIELEANDEQ
LDFPVVYASAINGTASLDAATQDENMQSLYETIIDYIPAPVDNREEDLQFQVALLDYNDYVGRIGIGRVFRGTMEVGQQV
SLIKLDGTIKNFRVTKIFGFFGLKRVEIQKAYAGDLIAVSGMEDINVGETVAPVDNPEALPVLRIDEPTLQMTFSVNNSP
FAGKEGKFVTARNIQDRLESQLETDVSLRVESVGPDSWTVSGRGELHLSILIENMRREGFELQVSKPEVIVKEIDGKKYE
PYERVQIDVPEEHTGSVIESLGVRKGEMVDMVNGGNGQTRLIFNVPARGLIGYRTEFMSMTRGYGILNHTFDEYRPLLKG
RIGGRRNGVLVSIDKGVASTYAILALEDRGVNFMEPGTEVYEGMIVGENSRDNDLTVNITKVKAANNIRSATKEQTTTMK
KPRILTLEEALEYLNDDELVEVTPESIRLRKKTLDKSQREREQKKAKAALQEEE

Sequences:

>Translated_614_residues
MTKLREDVRNIAIIAHVDHGKTTLVDELLKQSGTFRENEQVDERAMDSNDIERERGITILAKNTAIDYKGTRINILDTPG
HADFGGEVERIMKMVDGVILVVDAYEGTMPQTRFVLKKALEQNLKPVVVVNKIDKPSARPEEVLDEVYDLFIELEANDEQ
LDFPVVYASAINGTASLDAATQDENMQSLYETIIDYIPAPVDNREEDLQFQVALLDYNDYVGRIGIGRVFRGTMEVGQQV
SLIKLDGTIKNFRVTKIFGFFGLKRVEIQKAYAGDLIAVSGMEDINVGETVAPVDNPEALPVLRIDEPTLQMTFSVNNSP
FAGKEGKFVTARNIQDRLESQLETDVSLRVESVGPDSWTVSGRGELHLSILIENMRREGFELQVSKPEVIVKEIDGKKYE
PYERVQIDVPEEHTGSVIESLGVRKGEMVDMVNGGNGQTRLIFNVPARGLIGYRTEFMSMTRGYGILNHTFDEYRPLLKG
RIGGRRNGVLVSIDKGVASTYAILALEDRGVNFMEPGTEVYEGMIVGENSRDNDLTVNITKVKAANNIRSATKEQTTTMK
KPRILTLEEALEYLNDDELVEVTPESIRLRKKTLDKSQREREQKKAKAALQEEE
>Mature_613_residues
TKLREDVRNIAIIAHVDHGKTTLVDELLKQSGTFRENEQVDERAMDSNDIERERGITILAKNTAIDYKGTRINILDTPGH
ADFGGEVERIMKMVDGVILVVDAYEGTMPQTRFVLKKALEQNLKPVVVVNKIDKPSARPEEVLDEVYDLFIELEANDEQL
DFPVVYASAINGTASLDAATQDENMQSLYETIIDYIPAPVDNREEDLQFQVALLDYNDYVGRIGIGRVFRGTMEVGQQVS
LIKLDGTIKNFRVTKIFGFFGLKRVEIQKAYAGDLIAVSGMEDINVGETVAPVDNPEALPVLRIDEPTLQMTFSVNNSPF
AGKEGKFVTARNIQDRLESQLETDVSLRVESVGPDSWTVSGRGELHLSILIENMRREGFELQVSKPEVIVKEIDGKKYEP
YERVQIDVPEEHTGSVIESLGVRKGEMVDMVNGGNGQTRLIFNVPARGLIGYRTEFMSMTRGYGILNHTFDEYRPLLKGR
IGGRRNGVLVSIDKGVASTYAILALEDRGVNFMEPGTEVYEGMIVGENSRDNDLTVNITKVKAANNIRSATKEQTTTMKK
PRILTLEEALEYLNDDELVEVTPESIRLRKKTLDKSQREREQKKAKAALQEEE

Specific function: Not known; probably interacts with the ribosomes in a GTP dependent manner [H]

COG id: COG1217

COG function: function code T; Predicted membrane GTPase involved in stress response

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. TypA subfamily [H]

Homologues:

Organism=Homo sapiens, GI157426893, Length=511, Percent_Identity=27.0058708414873, Blast_Score=145, Evalue=9e-35,
Organism=Homo sapiens, GI94966754, Length=133, Percent_Identity=44.3609022556391, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI25306283, Length=168, Percent_Identity=37.5, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI19923640, Length=168, Percent_Identity=37.5, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI25306287, Length=168, Percent_Identity=37.5, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI18390331, Length=147, Percent_Identity=38.7755102040816, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI4503483, Length=149, Percent_Identity=37.5838926174497, Blast_Score=107, Evalue=4e-23,
Organism=Homo sapiens, GI34147630, Length=276, Percent_Identity=32.6086956521739, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI310132016, Length=111, Percent_Identity=41.4414414414414, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI310110807, Length=111, Percent_Identity=41.4414414414414, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI310123363, Length=111, Percent_Identity=41.4414414414414, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI217272892, Length=136, Percent_Identity=37.5, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI217272894, Length=136, Percent_Identity=37.5, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI94966752, Length=129, Percent_Identity=34.1085271317829, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI53729339, Length=165, Percent_Identity=34.5454545454545, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI53729337, Length=165, Percent_Identity=34.5454545454545, Blast_Score=79, Evalue=2e-14,
Organism=Escherichia coli, GI48994988, Length=603, Percent_Identity=56.2189054726368, Blast_Score=701, Evalue=0.0,
Organism=Escherichia coli, GI1788922, Length=511, Percent_Identity=29.3542074363992, Blast_Score=172, Evalue=5e-44,
Organism=Escherichia coli, GI1789738, Length=148, Percent_Identity=39.1891891891892, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1790835, Length=175, Percent_Identity=29.7142857142857, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI1789737, Length=250, Percent_Identity=30.4, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1790412, Length=250, Percent_Identity=30.4, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1789559, Length=166, Percent_Identity=34.3373493975904, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17557151, Length=526, Percent_Identity=25.8555133079848, Blast_Score=136, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17556745, Length=142, Percent_Identity=43.6619718309859, Blast_Score=121, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17533571, Length=177, Percent_Identity=37.8531073446328, Blast_Score=118, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17506493, Length=177, Percent_Identity=32.7683615819209, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71988811, Length=134, Percent_Identity=35.0746268656716, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71988819, Length=134, Percent_Identity=35.0746268656716, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17552882, Length=134, Percent_Identity=36.5671641791045, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17556456, Length=302, Percent_Identity=27.1523178807947, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71994658, Length=187, Percent_Identity=33.6898395721925, Blast_Score=79, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI25141371, Length=250, Percent_Identity=28.4, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6323320, Length=517, Percent_Identity=29.2069632495164, Blast_Score=151, Evalue=4e-37,
Organism=Saccharomyces cerevisiae, GI6324707, Length=163, Percent_Identity=38.6503067484663, Blast_Score=114, Evalue=5e-26,
Organism=Saccharomyces cerevisiae, GI6320593, Length=163, Percent_Identity=38.6503067484663, Blast_Score=114, Evalue=5e-26,
Organism=Saccharomyces cerevisiae, GI6323098, Length=179, Percent_Identity=34.0782122905028, Blast_Score=99, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6324761, Length=272, Percent_Identity=30.8823529411765, Blast_Score=98, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6324166, Length=180, Percent_Identity=33.8888888888889, Blast_Score=94, Evalue=9e-20,
Organism=Saccharomyces cerevisiae, GI6322359, Length=149, Percent_Identity=36.241610738255, Blast_Score=91, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6324550, Length=294, Percent_Identity=27.5510204081633, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI78706572, Length=528, Percent_Identity=27.6515151515151, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24582462, Length=177, Percent_Identity=36.7231638418079, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI28574573, Length=144, Percent_Identity=41.6666666666667, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI24585709, Length=169, Percent_Identity=34.3195266272189, Blast_Score=107, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24585711, Length=169, Percent_Identity=34.3195266272189, Blast_Score=107, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24585713, Length=169, Percent_Identity=34.3195266272189, Blast_Score=107, Evalue=3e-23,
Organism=Drosophila melanogaster, GI21357743, Length=134, Percent_Identity=39.5522388059701, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI281363316, Length=273, Percent_Identity=30.03663003663, Blast_Score=94, Evalue=4e-19,
Organism=Drosophila melanogaster, GI17864358, Length=273, Percent_Identity=30.03663003663, Blast_Score=94, Evalue=4e-19,
Organism=Drosophila melanogaster, GI221458488, Length=160, Percent_Identity=39.375, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28572034, Length=165, Percent_Identity=35.7575757575758, Blast_Score=83, Evalue=6e-16,
Organism=Drosophila melanogaster, GI19921738, Length=301, Percent_Identity=27.2425249169435, Blast_Score=82, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR000640
- InterPro:   IPR004161
- InterPro:   IPR009000
- InterPro:   IPR006298 [H]

Pfam domain/function: PF00679 EFG_C; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 68854; Mature: 68723

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKLREDVRNIAIIAHVDHGKTTLVDELLKQSGTFRENEQVDERAMDSNDIERERGITIL
CCHHHHHHCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCHHHCCEEEE
AKNTAIDYKGTRINILDTPGHADFGGEVERIMKMVDGVILVVDAYEGTMPQTRFVLKKAL
EECEEEEECCCEEEEEECCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHH
EQNLKPVVVVNKIDKPSARPEEVLDEVYDLFIELEANDEQLDFPVVYASAINGTASLDAA
HCCCCCEEEEECCCCCCCCHHHHHHHHHHEEEEEECCCCCCCCCEEEEEECCCCCCCCCC
TQDENMQSLYETIIDYIPAPVDNREEDLQFQVALLDYNDYVGRIGIGRVFRGTMEVGQQV
CCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHCCEE
SLIKLDGTIKNFRVTKIFGFFGLKRVEIQKAYAGDLIAVSGMEDINVGETVAPVDNPEAL
EEEEECCCCCCEEEEEEHHHHCCEEEEEEHHHCCCEEEECCCCCCCCCCEECCCCCCCCC
PVLRIDEPTLQMTFSVNNSPFAGKEGKFVTARNIQDRLESQLETDVSLRVESVGPDSWTV
EEEEECCCCEEEEEEECCCCCCCCCCCEEEECCHHHHHHHHHCCCEEEEEEEECCCCEEE
SGRGELHLSILIENMRREGFELQVSKPEVIVKEIDGKKYEPYERVQIDVPEEHTGSVIES
CCCCCEEEEEEEHHHHCCCCEEEECCCEEEEEECCCCCCCCCCEEEEECCCHHHHHHHHH
LGVRKGEMVDMVNGGNGQTRLIFNVPARGLIGYRTEFMSMTRGYGILNHTFDEYRPLLKG
HCCCCCCEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCHHCCHHHHHHHHHC
RIGGRRNGVLVSIDKGVASTYAILALEDRGVNFMEPGTEVYEGMIVGENSRDNDLTVNIT
CCCCCCCCEEEEECCCCCCEEEEEEEECCCCCCCCCCHHHHCCEEEECCCCCCCEEEEEE
KVKAANNIRSATKEQTTTMKKPRILTLEEALEYLNDDELVEVTPESIRLRKKTLDKSQRE
EEECCCHHHHHHHHHHHHCCCCEEEEHHHHHHHCCCCCEEEECHHHHHHHHHHHCHHHHH
REQKKAKAALQEEE
HHHHHHHHHCCCCC
>Mature Secondary Structure 
TKLREDVRNIAIIAHVDHGKTTLVDELLKQSGTFRENEQVDERAMDSNDIERERGITIL
CHHHHHHCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCHHHCCEEEE
AKNTAIDYKGTRINILDTPGHADFGGEVERIMKMVDGVILVVDAYEGTMPQTRFVLKKAL
EECEEEEECCCEEEEEECCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHH
EQNLKPVVVVNKIDKPSARPEEVLDEVYDLFIELEANDEQLDFPVVYASAINGTASLDAA
HCCCCCEEEEECCCCCCCCHHHHHHHHHHEEEEEECCCCCCCCCEEEEEECCCCCCCCCC
TQDENMQSLYETIIDYIPAPVDNREEDLQFQVALLDYNDYVGRIGIGRVFRGTMEVGQQV
CCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHCCEE
SLIKLDGTIKNFRVTKIFGFFGLKRVEIQKAYAGDLIAVSGMEDINVGETVAPVDNPEAL
EEEEECCCCCCEEEEEEHHHHCCEEEEEEHHHCCCEEEECCCCCCCCCCEECCCCCCCCC
PVLRIDEPTLQMTFSVNNSPFAGKEGKFVTARNIQDRLESQLETDVSLRVESVGPDSWTV
EEEEECCCCEEEEEEECCCCCCCCCCCEEEECCHHHHHHHHHCCCEEEEEEEECCCCEEE
SGRGELHLSILIENMRREGFELQVSKPEVIVKEIDGKKYEPYERVQIDVPEEHTGSVIES
CCCCCEEEEEEEHHHHCCCCEEEECCCEEEEEECCCCCCCCCCEEEEECCCHHHHHHHHH
LGVRKGEMVDMVNGGNGQTRLIFNVPARGLIGYRTEFMSMTRGYGILNHTFDEYRPLLKG
HCCCCCCEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCHHCCHHHHHHHHHC
RIGGRRNGVLVSIDKGVASTYAILALEDRGVNFMEPGTEVYEGMIVGENSRDNDLTVNIT
CCCCCCCCEEEEECCCCCCEEEEEEEECCCCCCCCCCHHHHCCEEEECCCCCCCEEEEEE
KVKAANNIRSATKEQTTTMKKPRILTLEEALEYLNDDELVEVTPESIRLRKKTLDKSQRE
EEECCCHHHHHHHHHHHHCCCCEEEEHHHHHHHCCCCCEEEECHHHHHHHHHHHCHHHHH
REQKKAKAALQEEE
HHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]