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The map label for this gene is tagH [H]

Identifier: 222150915

GI number: 222150915

Start: 716555

End: 717508

Strand: Direct

Name: tagH [H]

Synonym: MCCL_0665

Alternate gene names: 222150915

Gene position: 716555-717508 (Clockwise)

Preceding gene: 222150914

Following gene: 222150916

Centisome position: 34.08

GC content: 39.94

Gene sequence:

>954_bases
ATGGAGGCAGTGAAAGTAAAGGTCAATAACGTATCTAAAGCATATCCGGTCAATCAGAGTAAAAGTCAGAAAATACTGGA
TATCCTTAAGTTCTGGCAGCATAAGACGCATGACGATGTGTATTATGCGCTGAAAGATATCAGCTTCGAAGTGAATGCTG
GAGACAGTGTTGGGCTCGTTGGATTAAATGGTGCCGGTAAATCAACGCTCTCAAACCTCTTGGGAGAAGTCATCTCACCT
ACTGCAGGGACGATTGAAATAAACGGCCGAAGCTCACTGATCGCTATATCTGCAGGATTAAACAATGAACTATCAGGGGA
AGAGAATATCCGTATGAAATGTCTGATGCATGGTCTGACTGAAGAACAGATCAATGCGCGTTTTAATGATATCATCGACT
TCTCTGAACTCGGAGACTTCATTAAAAAACCGATTAAGACGTATTCCAGCGGGATGAAATCACGACTTGGTTTTGCGATC
GCTGTCCATACAGATCCAGACGTACTCATCGTGGATGAAGCGCTGTCTGTAGGAGATGACACATTTTCTAATAAATGCAT
CGAACGTATGAAAGCTTTTCAAGAAGAAGGGAAGACCATCTTCTTTGTCAGTCACTCTATTGGTCAGATACAGAAGATGT
GCAATAAAGCGATATGGATTCATTATGGCAAAATTGAAGCGCAAGGAGACTGTATTCCGACGGTCGGTTTATATGGCAGG
TTTATCAGAAGATACAATCAGTTTGATAAAGAACAGCAGCTTGCATATAAAGAAGCACAGCTTCAGAATCAGATCGGCTC
GATCAACGACATACAAGTTAATAAAGAAAATGTATCTAAGAATACATTGTTCGGTCTGATCGGTGTTACAGCATTATTTA
TATTCAGTATGCTGTCTCAATTAAATGTCATACCACTATCACATTATCTAAATATGTTAAAAGGGATGTTTTAA

Upstream 100 bases:

>100_bases
TACAAAGTAGATATGAACCATTTTTCTGCATATGGAGCAACTGTTCGTGAAATAAACAAACACCTTAATAAAGCGTTAAC
ACTGAAAGAGGAGGTGTCTT

Downstream 100 bases:

>100_bases
CCGTGAAAAAGGTGACCATGTTTGTCTGGAACAACTTTACCAATGACGCAAGAGTGACGAGAGAAGCGAAGACACTTCAG
TCACATTATGATGTCACTGT

Product: hypothetical protein

Products: NA

Alternate protein names: Teichoic acid-transporting ATPase [H]

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MEAVKVKVNNVSKAYPVNQSKSQKILDILKFWQHKTHDDVYYALKDISFEVNAGDSVGLVGLNGAGKSTLSNLLGEVISP
TAGTIEINGRSSLIAISAGLNNELSGEENIRMKCLMHGLTEEQINARFNDIIDFSELGDFIKKPIKTYSSGMKSRLGFAI
AVHTDPDVLIVDEALSVGDDTFSNKCIERMKAFQEEGKTIFFVSHSIGQIQKMCNKAIWIHYGKIEAQGDCIPTVGLYGR
FIRRYNQFDKEQQLAYKEAQLQNQIGSINDIQVNKENVSKNTLFGLIGVTALFIFSMLSQLNVIPLSHYLNMLKGMF

Sequences:

>Translated_317_residues
MEAVKVKVNNVSKAYPVNQSKSQKILDILKFWQHKTHDDVYYALKDISFEVNAGDSVGLVGLNGAGKSTLSNLLGEVISP
TAGTIEINGRSSLIAISAGLNNELSGEENIRMKCLMHGLTEEQINARFNDIIDFSELGDFIKKPIKTYSSGMKSRLGFAI
AVHTDPDVLIVDEALSVGDDTFSNKCIERMKAFQEEGKTIFFVSHSIGQIQKMCNKAIWIHYGKIEAQGDCIPTVGLYGR
FIRRYNQFDKEQQLAYKEAQLQNQIGSINDIQVNKENVSKNTLFGLIGVTALFIFSMLSQLNVIPLSHYLNMLKGMF
>Mature_317_residues
MEAVKVKVNNVSKAYPVNQSKSQKILDILKFWQHKTHDDVYYALKDISFEVNAGDSVGLVGLNGAGKSTLSNLLGEVISP
TAGTIEINGRSSLIAISAGLNNELSGEENIRMKCLMHGLTEEQINARFNDIIDFSELGDFIKKPIKTYSSGMKSRLGFAI
AVHTDPDVLIVDEALSVGDDTFSNKCIERMKAFQEEGKTIFFVSHSIGQIQKMCNKAIWIHYGKIEAQGDCIPTVGLYGR
FIRRYNQFDKEQQLAYKEAQLQNQIGSINDIQVNKENVSKNTLFGLIGVTALFIFSMLSQLNVIPLSHYLNMLKGMF

Specific function: Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system [H]

COG id: COG1134

COG function: function code GM; ABC-type polysaccharide/polyol phosphate transport system, ATPase component

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI31657092, Length=212, Percent_Identity=30.188679245283, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI30795238, Length=212, Percent_Identity=25.9433962264151, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI27881501, Length=212, Percent_Identity=25.9433962264151, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI6005701, Length=196, Percent_Identity=24.4897959183673, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI153792144, Length=213, Percent_Identity=23.4741784037559, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI45446740, Length=214, Percent_Identity=26.1682242990654, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI47078218, Length=214, Percent_Identity=26.1682242990654, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI27477115, Length=196, Percent_Identity=23.9795918367347, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI27262624, Length=267, Percent_Identity=24.3445692883895, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI27262626, Length=267, Percent_Identity=24.3445692883895, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI116734710, Length=200, Percent_Identity=27, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI27436953, Length=194, Percent_Identity=22.680412371134, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI105990541, Length=199, Percent_Identity=25.1256281407035, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI21536376, Length=209, Percent_Identity=25.3588516746411, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI150417984, Length=212, Percent_Identity=25.4716981132075, Blast_Score=65, Evalue=1e-10,
Organism=Escherichia coli, GI87081791, Length=261, Percent_Identity=24.904214559387, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1787547, Length=209, Percent_Identity=26.7942583732057, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786398, Length=249, Percent_Identity=24.8995983935743, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788506, Length=250, Percent_Identity=25.6, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI87081782, Length=201, Percent_Identity=27.363184079602, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1789032, Length=242, Percent_Identity=23.9669421487603, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787758, Length=209, Percent_Identity=24.8803827751196, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI48994943, Length=202, Percent_Identity=25.2475247524752, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787089, Length=210, Percent_Identity=24.2857142857143, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1790467, Length=197, Percent_Identity=24.8730964467005, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787105, Length=223, Percent_Identity=26.0089686098655, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787029, Length=237, Percent_Identity=24.0506329113924, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790739, Length=203, Percent_Identity=24.1379310344828, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87082267, Length=221, Percent_Identity=23.5294117647059, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1786319, Length=203, Percent_Identity=24.6305418719212, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789873, Length=202, Percent_Identity=26.2376237623762, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788210, Length=244, Percent_Identity=27.0491803278689, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17565586, Length=227, Percent_Identity=32.15859030837, Blast_Score=101, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI115533608, Length=213, Percent_Identity=28.169014084507, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71983523, Length=207, Percent_Identity=25.1207729468599, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71983510, Length=207, Percent_Identity=25.1207729468599, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71983516, Length=207, Percent_Identity=25.1207729468599, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI193209708, Length=209, Percent_Identity=31.1004784688995, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193202349, Length=205, Percent_Identity=28.2926829268293, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17510237, Length=197, Percent_Identity=23.3502538071066, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17569145, Length=252, Percent_Identity=27.7777777777778, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24648314, Length=188, Percent_Identity=25, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24643674, Length=188, Percent_Identity=27.1276595744681, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI221512771, Length=184, Percent_Identity=26.6304347826087, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28573571, Length=201, Percent_Identity=23.3830845771144, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28573573, Length=201, Percent_Identity=23.3830845771144, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI28574150, Length=231, Percent_Identity=24.2424242424242, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI116007328, Length=231, Percent_Identity=23.8095238095238, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI116007184, Length=188, Percent_Identity=24.468085106383, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI221500365, Length=188, Percent_Identity=24.468085106383, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24666092, Length=198, Percent_Identity=26.7676767676768, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR015860
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: =3.6.3.40 [H]

Molecular weight: Translated: 35285; Mature: 35285

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAVKVKVNNVSKAYPVNQSKSQKILDILKFWQHKTHDDVYYALKDISFEVNAGDSVGLV
CCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCEEEECCCCCEEEE
GLNGAGKSTLSNLLGEVISPTAGTIEINGRSSLIAISAGLNNELSGEENIRMKCLMHGLT
EECCCCHHHHHHHHHHHHCCCCCEEEECCCCEEEEEECCCCCCCCCCCCHHHHHHHHCCC
EEQINARFNDIIDFSELGDFIKKPIKTYSSGMKSRLGFAIAVHTDPDVLIVDEALSVGDD
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEEECHHHCCCC
TFSNKCIERMKAFQEEGKTIFFVSHSIGQIQKMCNKAIWIHYGKIEAQGDCIPTVGLYGR
HHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCEEEEEEEEEEECCCCCCCHHHHHH
FIRRYNQFDKEQQLAYKEAQLQNQIGSINDIQVNKENVSKNTLFGLIGVTALFIFSMLSQ
HHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEECHHHCCHHHHHHHHHHHHHHHHHHHHH
LNVIPLSHYLNMLKGMF
CCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MEAVKVKVNNVSKAYPVNQSKSQKILDILKFWQHKTHDDVYYALKDISFEVNAGDSVGLV
CCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCEEEECCCCCEEEE
GLNGAGKSTLSNLLGEVISPTAGTIEINGRSSLIAISAGLNNELSGEENIRMKCLMHGLT
EECCCCHHHHHHHHHHHHCCCCCEEEECCCCEEEEEECCCCCCCCCCCCHHHHHHHHCCC
EEQINARFNDIIDFSELGDFIKKPIKTYSSGMKSRLGFAIAVHTDPDVLIVDEALSVGDD
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEEECHHHCCCC
TFSNKCIERMKAFQEEGKTIFFVSHSIGQIQKMCNKAIWIHYGKIEAQGDCIPTVGLYGR
HHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCEEEEEEEEEEECCCCCCCHHHHHH
FIRRYNQFDKEQQLAYKEAQLQNQIGSINDIQVNKENVSKNTLFGLIGVTALFIFSMLSQ
HHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEECHHHCCHHHHHHHHHHHHHHHHHHHHH
LNVIPLSHYLNMLKGMF
CCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7565096; 9384377 [H]