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The map label for this gene is tagH [H]

Identifier: 222150900

GI number: 222150900

Start: 700368

End: 701171

Strand: Direct

Name: tagH [H]

Synonym: MCCL_0650

Alternate gene names: 222150900

Gene position: 700368-701171 (Clockwise)

Preceding gene: 222150899

Following gene: 222150903

Centisome position: 33.31

GC content: 31.22

Gene sequence:

>804_bases
ATGAATGAATCAGTAGTAATTAAAAATGTAACCAAGAAATATAGAATGTACAAATCTAATAAGGAAAGATTAAAAGATCT
AATAATCCCAGGTAAAGCGGGAGAGGATTTTTATGCACTTCAAGATATTACGTTTACCGCTTATGAAGGTGATGTAATCG
GACTTGTCGGTATCAATGGTTCAGGTAAGTCGACATTATCGAATATAATAGGAGGCATCATACCACCTACTGAAGGTAAC
TTAGAAAAATATGGAGAAGTTAACGTAATTGCTATTAATGCTGGATTAAATGGAAATTTAACAGGTATGGAAAACATTGA
ATTTAAATGTCTGTTATTAGGTTATTCTCAGAAACAAATTAAAGCACTTACGCCTGAGATAGTAAAATTCTCGGAGTTAG
GGGATTTTATTTATCAGCCCGTGAAAAAATATTCTAGTGGTATGAAATCAAAGTTGGGCTTTGCTATTAGTGTCACTGTA
AATCCTGATATTCTAGTAATAGACGAAGCATTATCGGTTGGTGATCAGACATTTGCTGATAAAAGCTTAGCAAAAATGCA
AGAGTTTAAAGAGCAGAATAAAACAATATTTTTTGTGAGTCACAACTTAGGACAAGTAAAGAAATTCTGTACAAAAATTG
CTTGGATTGAGGGCGGATTTTTAAAAGAATTTGGTGACAAAGATACTGTTATGAAGCATTATGAAGAGTTTATTAATGAT
TTCAAAAAGATGAGTAAAGAAGAACAAGAACATTTTAAGAAAAATTTAAATGATAAAAGAAAAGTAAGAAAAAAATCGCA
GTAG

Upstream 100 bases:

>100_bases
CTATAGATTTTGCCTTAAAAAACGAAGAAATGCGTGAAGAAGTAATGGAATATATCAAGAGAATCGCGCAACAATAAGCC
AGTGAATAGGTGAATAAGTT

Downstream 100 bases:

>100_bases
TCTTATGACTATTGCGATTTTTGATTAAATTAATTGCCATAAAGTTCTTTTTTTATTTGAGTTGTAGATATGCCTTCAGT
TCTTTCTAAGTAAACGACTT

Product: teichoic acids export protein ATP-binding subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MNESVVIKNVTKKYRMYKSNKERLKDLIIPGKAGEDFYALQDITFTAYEGDVIGLVGINGSGKSTLSNIIGGIIPPTEGN
LEKYGEVNVIAINAGLNGNLTGMENIEFKCLLLGYSQKQIKALTPEIVKFSELGDFIYQPVKKYSSGMKSKLGFAISVTV
NPDILVIDEALSVGDQTFADKSLAKMQEFKEQNKTIFFVSHNLGQVKKFCTKIAWIEGGFLKEFGDKDTVMKHYEEFIND
FKKMSKEEQEHFKKNLNDKRKVRKKSQ

Sequences:

>Translated_267_residues
MNESVVIKNVTKKYRMYKSNKERLKDLIIPGKAGEDFYALQDITFTAYEGDVIGLVGINGSGKSTLSNIIGGIIPPTEGN
LEKYGEVNVIAINAGLNGNLTGMENIEFKCLLLGYSQKQIKALTPEIVKFSELGDFIYQPVKKYSSGMKSKLGFAISVTV
NPDILVIDEALSVGDQTFADKSLAKMQEFKEQNKTIFFVSHNLGQVKKFCTKIAWIEGGFLKEFGDKDTVMKHYEEFIND
FKKMSKEEQEHFKKNLNDKRKVRKKSQ
>Mature_267_residues
MNESVVIKNVTKKYRMYKSNKERLKDLIIPGKAGEDFYALQDITFTAYEGDVIGLVGINGSGKSTLSNIIGGIIPPTEGN
LEKYGEVNVIAINAGLNGNLTGMENIEFKCLLLGYSQKQIKALTPEIVKFSELGDFIYQPVKKYSSGMKSKLGFAISVTV
NPDILVIDEALSVGDQTFADKSLAKMQEFKEQNKTIFFVSHNLGQVKKFCTKIAWIEGGFLKEFGDKDTVMKHYEEFIND
FKKMSKEEQEHFKKNLNDKRKVRKKSQ

Specific function: Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system [H]

COG id: COG1134

COG function: function code GM; ABC-type polysaccharide/polyol phosphate transport system, ATPase component

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI27436953, Length=196, Percent_Identity=28.0612244897959, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI31657092, Length=265, Percent_Identity=25.6603773584906, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI27262624, Length=238, Percent_Identity=27.3109243697479, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI27262626, Length=238, Percent_Identity=27.3109243697479, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI27477115, Length=197, Percent_Identity=26.9035532994924, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI45446740, Length=196, Percent_Identity=28.0612244897959, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI47078218, Length=196, Percent_Identity=28.0612244897959, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI6005701, Length=197, Percent_Identity=26.3959390862944, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI27881501, Length=241, Percent_Identity=26.1410788381743, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI30795238, Length=241, Percent_Identity=26.1410788381743, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI153792144, Length=203, Percent_Identity=24.6305418719212, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI116734710, Length=230, Percent_Identity=23.9130434782609, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1789032, Length=212, Percent_Identity=24.5283018867925, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787758, Length=209, Percent_Identity=24.8803827751196, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787029, Length=209, Percent_Identity=26.7942583732057, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI87081791, Length=233, Percent_Identity=23.175965665236, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI48994943, Length=195, Percent_Identity=24.6153846153846, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI87081782, Length=201, Percent_Identity=28.8557213930348, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1787089, Length=208, Percent_Identity=24.5192307692308, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786563, Length=190, Percent_Identity=24.2105263157895, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1788761, Length=209, Percent_Identity=23.444976076555, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1786398, Length=209, Percent_Identity=24.8803827751196, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787712, Length=220, Percent_Identity=20.9090909090909, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI87081709, Length=215, Percent_Identity=21.8604651162791, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1790467, Length=224, Percent_Identity=23.6607142857143, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87082267, Length=198, Percent_Identity=21.2121212121212, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI115533608, Length=269, Percent_Identity=23.4200743494424, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17510237, Length=207, Percent_Identity=25.6038647342995, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24643674, Length=235, Percent_Identity=25.531914893617, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI221512771, Length=208, Percent_Identity=24.0384615384615, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28573573, Length=201, Percent_Identity=25.3731343283582, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28573571, Length=201, Percent_Identity=25.3731343283582, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24648314, Length=226, Percent_Identity=22.1238938053097, Blast_Score=67, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR015860
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: =3.6.3.40 [H]

Molecular weight: Translated: 30066; Mature: 30066

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNESVVIKNVTKKYRMYKSNKERLKDLIIPGKAGEDFYALQDITFTAYEGDVIGLVGING
CCCCEEEHHHHHHHHHHHCCHHHHHHHCCCCCCCCCEEEEEEEEEEEECCCEEEEEEECC
SGKSTLSNIIGGIIPPTEGNLEKYGEVNVIAINAGLNGNLTGMENIEFKCLLLGYSQKQI
CCHHHHHHHHCCCCCCCCCCHHHCCCEEEEEEECCCCCCCCCCCCCEEEEEEECCCHHHH
KALTPEIVKFSELGDFIYQPVKKYSSGMKSKLGFAISVTVNPDILVIDEALSVGDQTFAD
HHHCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCEEEEEEECCCEEEEECHHHCCCHHHHH
KSLAKMQEFKEQNKTIFFVSHNLGQVKKFCTKIAWIEGGFLKEFGDKDTVMKHYEEFIND
HHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHH
FKKMSKEEQEHFKKNLNDKRKVRKKSQ
HHHHHHHHHHHHHHCCCHHHHHHHCCC
>Mature Secondary Structure
MNESVVIKNVTKKYRMYKSNKERLKDLIIPGKAGEDFYALQDITFTAYEGDVIGLVGING
CCCCEEEHHHHHHHHHHHCCHHHHHHHCCCCCCCCCEEEEEEEEEEEECCCEEEEEEECC
SGKSTLSNIIGGIIPPTEGNLEKYGEVNVIAINAGLNGNLTGMENIEFKCLLLGYSQKQI
CCHHHHHHHHCCCCCCCCCCHHHCCCEEEEEEECCCCCCCCCCCCCEEEEEEECCCHHHH
KALTPEIVKFSELGDFIYQPVKKYSSGMKSKLGFAISVTVNPDILVIDEALSVGDQTFAD
HHHCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCEEEEEEECCCEEEEECHHHCCCHHHHH
KSLAKMQEFKEQNKTIFFVSHNLGQVKKFCTKIAWIEGGFLKEFGDKDTVMKHYEEFIND
HHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHH
FKKMSKEEQEHFKKNLNDKRKVRKKSQ
HHHHHHHHHHHHHHCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA