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The map label for this gene is ycgM [C]

Identifier: 222150844

GI number: 222150844

Start: 635315

End: 636214

Strand: Direct

Name: ycgM [C]

Synonym: MCCL_0594

Alternate gene names: 222150844

Gene position: 635315-636214 (Clockwise)

Preceding gene: 222150843

Following gene: 222150845

Centisome position: 30.22

GC content: 40.78

Gene sequence:

>900_bases
ATGAAATTTTTGTCGTTTGAGTATAAAGGTAAACAATCTTTCGGTGTAAAGGTTAAAAGAGAAGATGCAGCATGGGATCT
CGTACGTGTATTTGAAGCAACCAATACAGCGAATTACCCAAAGACATTATTAGAGGCATTACAGCAAAACAATACGCTCG
ACTTTCAGGAACTTGTACGTAAAACAATCGAACAGATAGAGCGAGAGAAGGATGCCGAAGATTACAAAGTTGCATATACA
GATATGACGTTCCTGCCGCCTGTTGTTCCGACTAATAATGTCATCGCTATTGGACGAAATTATTCAGATCATGCGAAGGA
AATGAACAATGATGTGGATGAACTCTATGTCTTTACGAAAGCACCTTCAAGCTTAATTGGAGATGGCGCTCGCATCCCAT
CACATGCTGACGTAACACAAGCCCTTGACTATGAAGGAGAACTTGGTATTGTCATCGGTAAATACGGTCATAAGATTCCT
AAAGCATTAGCATTGGATTATGTTTATGGTTATACAATCATTAATGACATTACGGCACGTGACCTGCAGAAGGCACACGC
TCAGGCATTCTTATCTAAAAGCTTATTAGGTGCTTGTCCTATGGGACCATATATTGTAACGAAAGATGAACTGCCAATGC
CAGAAAATGCAAATATCGTGACGAAAGTGAACGGTGAGATTCGTCAAGATGGCAATACGCAAGATATGGTGAAGAAAATA
GACGATCTGATTGCCGAGATTTCACAATATATTGCACTACACCCGGGTGATGTTATCGCAACAGGTACACCAAGCGGCGT
AGGTGCAGGAATGAATCCACCTGCATACTTGAAGCGTGGGGATGAAATTAAAGTAACGATTGACGGTATCGGTACTTTAC
AGAATACAATCGAAGAATAG

Upstream 100 bases:

>100_bases
AAAGAGTAAATTCAAAAAAATCTGAAAAATAACTCTAAAACAATGAAACATCATCTTATTTTCTGTATAATGAAACAAAG
TATAAGAAGGAGTGGAATTC

Downstream 100 bases:

>100_bases
TATCCTTTTATTCATACAGTTATTTTGGTACAAGTATAAGAATCTATGTTAAACTAATAACAGTATGAATAAAAAGGAGT
GAATTACATGGAAACTGGTA

Product: fumarylacetoacetate hydrolase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MKFLSFEYKGKQSFGVKVKREDAAWDLVRVFEATNTANYPKTLLEALQQNNTLDFQELVRKTIEQIEREKDAEDYKVAYT
DMTFLPPVVPTNNVIAIGRNYSDHAKEMNNDVDELYVFTKAPSSLIGDGARIPSHADVTQALDYEGELGIVIGKYGHKIP
KALALDYVYGYTIINDITARDLQKAHAQAFLSKSLLGACPMGPYIVTKDELPMPENANIVTKVNGEIRQDGNTQDMVKKI
DDLIAEISQYIALHPGDVIATGTPSGVGAGMNPPAYLKRGDEIKVTIDGIGTLQNTIEE

Sequences:

>Translated_299_residues
MKFLSFEYKGKQSFGVKVKREDAAWDLVRVFEATNTANYPKTLLEALQQNNTLDFQELVRKTIEQIEREKDAEDYKVAYT
DMTFLPPVVPTNNVIAIGRNYSDHAKEMNNDVDELYVFTKAPSSLIGDGARIPSHADVTQALDYEGELGIVIGKYGHKIP
KALALDYVYGYTIINDITARDLQKAHAQAFLSKSLLGACPMGPYIVTKDELPMPENANIVTKVNGEIRQDGNTQDMVKKI
DDLIAEISQYIALHPGDVIATGTPSGVGAGMNPPAYLKRGDEIKVTIDGIGTLQNTIEE
>Mature_299_residues
MKFLSFEYKGKQSFGVKVKREDAAWDLVRVFEATNTANYPKTLLEALQQNNTLDFQELVRKTIEQIEREKDAEDYKVAYT
DMTFLPPVVPTNNVIAIGRNYSDHAKEMNNDVDELYVFTKAPSSLIGDGARIPSHADVTQALDYEGELGIVIGKYGHKIP
KALALDYVYGYTIINDITARDLQKAHAQAFLSKSLLGACPMGPYIVTKDELPMPENANIVTKVNGEIRQDGNTQDMVKKI
DDLIAEISQYIALHPGDVIATGTPSGVGAGMNPPAYLKRGDEIKVTIDGIGTLQNTIEE

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=263, Percent_Identity=39.5437262357414, Blast_Score=190, Evalue=1e-48,
Organism=Homo sapiens, GI40786394, Length=263, Percent_Identity=38.7832699619772, Blast_Score=188, Evalue=4e-48,
Organism=Homo sapiens, GI13654274, Length=213, Percent_Identity=38.0281690140845, Blast_Score=141, Evalue=6e-34,
Organism=Homo sapiens, GI215422413, Length=206, Percent_Identity=38.8349514563107, Blast_Score=139, Evalue=2e-33,
Organism=Homo sapiens, GI66348062, Length=206, Percent_Identity=38.8349514563107, Blast_Score=139, Evalue=3e-33,
Organism=Escherichia coli, GI1787428, Length=207, Percent_Identity=34.7826086956522, Blast_Score=110, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17557057, Length=179, Percent_Identity=39.6648044692737, Blast_Score=124, Evalue=6e-29,
Organism=Saccharomyces cerevisiae, GI6324161, Length=234, Percent_Identity=28.2051282051282, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI28572127, Length=300, Percent_Identity=36.3333333333333, Blast_Score=176, Evalue=1e-44,
Organism=Drosophila melanogaster, GI24663695, Length=248, Percent_Identity=33.4677419354839, Blast_Score=140, Evalue=8e-34,
Organism=Drosophila melanogaster, GI28571789, Length=210, Percent_Identity=32.8571428571429, Blast_Score=92, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 33045; Mature: 33045

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFLSFEYKGKQSFGVKVKREDAAWDLVRVFEATNTANYPKTLLEALQQNNTLDFQELVR
CCCEEEEECCCCCCCEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHH
KTIEQIEREKDAEDYKVAYTDMTFLPPVVPTNNVIAIGRNYSDHAKEMNNDVDELYVFTK
HHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCEEEECCCCHHHHHHHCCCHHHEEEEEC
APSSLIGDGARIPSHADVTQALDYEGELGIVIGKYGHKIPKALALDYVYGYTIINDITAR
CCHHHHCCCCCCCCCCCHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
DLQKAHAQAFLSKSLLGACPMGPYIVTKDELPMPENANIVTKVNGEIRQDGNTQDMVKKI
HHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHH
DDLIAEISQYIALHPGDVIATGTPSGVGAGMNPPAYLKRGDEIKVTIDGIGTLQNTIEE
HHHHHHHHHHHEECCCCEEECCCCCCCCCCCCCHHHHCCCCEEEEEECCCHHHHHHHCC
>Mature Secondary Structure
MKFLSFEYKGKQSFGVKVKREDAAWDLVRVFEATNTANYPKTLLEALQQNNTLDFQELVR
CCCEEEEECCCCCCCEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHH
KTIEQIEREKDAEDYKVAYTDMTFLPPVVPTNNVIAIGRNYSDHAKEMNNDVDELYVFTK
HHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCEEEECCCCHHHHHHHCCCHHHEEEEEC
APSSLIGDGARIPSHADVTQALDYEGELGIVIGKYGHKIPKALALDYVYGYTIINDITAR
CCHHHHCCCCCCCCCCCHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
DLQKAHAQAFLSKSLLGACPMGPYIVTKDELPMPENANIVTKVNGEIRQDGNTQDMVKKI
HHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHH
DDLIAEISQYIALHPGDVIATGTPSGVGAGMNPPAYLKRGDEIKVTIDGIGTLQNTIEE
HHHHHHHHHHHEECCCCEEECCCCCCCCCCCCCHHHHCCCCEEEEEECCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11418146 [H]