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The map label for this gene is comFA [H]

Identifier: 222150749

GI number: 222150749

Start: 528140

End: 529357

Strand: Direct

Name: comFA [H]

Synonym: MCCL_0499

Alternate gene names: 222150749

Gene position: 528140-529357 (Clockwise)

Preceding gene: 222150748

Following gene: 222150750

Centisome position: 25.12

GC content: 40.8

Gene sequence:

>1218_bases
ATGTTGCAACATATCACTGATAATGCTAATATTCCTTCTGTAATAACAAAAGGGAATAAATATCACTGTAACTATTGTTT
GAACGATAGACAATATTCCTTTCATAGCTTTTACCACGAGGGAGTAGGGAAGGAGATTGTGTATTGTCGTACTTGTCTCT
CTCATTATGCGACAACTGAGAACTTTATAGCACTTGAACCAAGCCCGAAGAAGGCGGAAGTTGTAACACTCCATCTCCCG
TTCGAACTTACAGCCCAGCAAAAGCGTGCGAGTGATTATATTGTGAGGCAGTTTCGTAAGAATCAAGATAGCCTGCTCTA
TGCTGTAACAGGTGCAGGTAAGACAGAGATGATGCTGCAGGCAGTTGTTGAAGCAAGAAAAGAAGGATGTAATGTTGCAA
TTACAGCACCGAGAACAGACGTGGTAAAAGAACTGGCACTGCGCATGCAGGAATATATGCCAGAAATACAGATTGATGTG
CTGTACGGAGGTCATCAGGTGCTAACGGCAGGTCATCTCATCGTCACAACTGTGCAGCAGCTTATTCAGTTTAATGGACA
TTTTGAATTAATTATCGTAGATGAAATTGATGCTTTCCCGATGAACTATGATCCACGCCTGTTAAAAGTGCTTAAACGGG
CTATGCATGAAAAAGGAACGATCATCTATCTGTCAGCCACACCACCTGCACATTTAATGAAACTACCTCATATCTATTTA
CCGTCACGCTATCATAATCGCCCCTTGCCGTTACCGAAACTTCGCTATTACAAAATTACGAGCAGGTCGTTAGAACAGAA
ACTCAAAAATATTGTTAATACGACGCTCATCTTCTTTAACGATATTAAACAAATGAAGAAATATTATGCTGCACTTCCTG
AATCTCTACAAGCGGAGGGGACGATTGTTTACTCAAATGATGATGAACGCCACGATAAAGTAGAGGCCATTCGAAGTGGG
GAATATCGCTTTATATTTACAACGACCATATTAGAGCGTGGATTTACGCAAGAGAACTTATCAGTCTGGGTCATCAATAG
TGAACAGTTTACATGGGACAGTCTCGTACAAATAGCAGGCAGGGTCGATAGAAAAGGGGCAAGTATGAATGGAGAAGTCG
TCTTCTTTCACGAAGGTCTAAGCAGCCATATGACGAAAGCAATACAAACAATTAAAAGGATGAATAAAAAGCATGATCAA
TCGATGTCTTCTGTGTGA

Upstream 100 bases:

>100_bases
GTTATGTACACCATAAGTTCGAATTTTTTCAGTAAAGTCTTTCATATTATTATTAATTCAGCACACTTATTTAAGTGTGC
TTATTTTTATGGAGGTCAAT

Downstream 100 bases:

>100_bases
AGCGCTGATACCACTTACCCTTACAGTTAATACATTATTCCATAAGCCGAAATTTTTATGTGAACAGTGTACTGCATCGT
TTACGAAGATGGATACGAGA

Product: hypothetical protein

Products: NA

Alternate protein names: ATP-dependent helicase ComFA [H]

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MLQHITDNANIPSVITKGNKYHCNYCLNDRQYSFHSFYHEGVGKEIVYCRTCLSHYATTENFIALEPSPKKAEVVTLHLP
FELTAQQKRASDYIVRQFRKNQDSLLYAVTGAGKTEMMLQAVVEARKEGCNVAITAPRTDVVKELALRMQEYMPEIQIDV
LYGGHQVLTAGHLIVTTVQQLIQFNGHFELIIVDEIDAFPMNYDPRLLKVLKRAMHEKGTIIYLSATPPAHLMKLPHIYL
PSRYHNRPLPLPKLRYYKITSRSLEQKLKNIVNTTLIFFNDIKQMKKYYAALPESLQAEGTIVYSNDDERHDKVEAIRSG
EYRFIFTTTILERGFTQENLSVWVINSEQFTWDSLVQIAGRVDRKGASMNGEVVFFHEGLSSHMTKAIQTIKRMNKKHDQ
SMSSV

Sequences:

>Translated_405_residues
MLQHITDNANIPSVITKGNKYHCNYCLNDRQYSFHSFYHEGVGKEIVYCRTCLSHYATTENFIALEPSPKKAEVVTLHLP
FELTAQQKRASDYIVRQFRKNQDSLLYAVTGAGKTEMMLQAVVEARKEGCNVAITAPRTDVVKELALRMQEYMPEIQIDV
LYGGHQVLTAGHLIVTTVQQLIQFNGHFELIIVDEIDAFPMNYDPRLLKVLKRAMHEKGTIIYLSATPPAHLMKLPHIYL
PSRYHNRPLPLPKLRYYKITSRSLEQKLKNIVNTTLIFFNDIKQMKKYYAALPESLQAEGTIVYSNDDERHDKVEAIRSG
EYRFIFTTTILERGFTQENLSVWVINSEQFTWDSLVQIAGRVDRKGASMNGEVVFFHEGLSSHMTKAIQTIKRMNKKHDQ
SMSSV
>Mature_405_residues
MLQHITDNANIPSVITKGNKYHCNYCLNDRQYSFHSFYHEGVGKEIVYCRTCLSHYATTENFIALEPSPKKAEVVTLHLP
FELTAQQKRASDYIVRQFRKNQDSLLYAVTGAGKTEMMLQAVVEARKEGCNVAITAPRTDVVKELALRMQEYMPEIQIDV
LYGGHQVLTAGHLIVTTVQQLIQFNGHFELIIVDEIDAFPMNYDPRLLKVLKRAMHEKGTIIYLSATPPAHLMKLPHIYL
PSRYHNRPLPLPKLRYYKITSRSLEQKLKNIVNTTLIFFNDIKQMKKYYAALPESLQAEGTIVYSNDDERHDKVEAIRSG
EYRFIFTTTILERGFTQENLSVWVINSEQFTWDSLVQIAGRVDRKGASMNGEVVFFHEGLSSHMTKAIQTIKRMNKKHDQ
SMSSV

Specific function: Involved in transformation (competence for DNA uptake). Required for DNA uptake but not for binding. May provide the driving force for transport of DNA through an aqueous channel [H]

COG id: COG4098

COG function: function code L; Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR006935 [H]

Pfam domain/function: PF00271 Helicase_C; PF04851 ResIII [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 46581; Mature: 46581

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQHITDNANIPSVITKGNKYHCNYCLNDRQYSFHSFYHEGVGKEIVYCRTCLSHYATTE
CCCCCCCCCCCCCEEECCCEEEEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCC
NFIALEPSPKKAEVVTLHLPFELTAQQKRASDYIVRQFRKNQDSLLYAVTGAGKTEMMLQ
CEEEECCCCCCEEEEEEEECCEECHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHH
AVVEARKEGCNVAITAPRTDVVKELALRMQEYMPEIQIDVLYGGHQVLTAGHLIVTTVQQ
HHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCCEEEEEEECCCEEECCCHHHHHHHHH
LIQFNGHFELIIVDEIDAFPMNYDPRLLKVLKRAMHEKGTIIYLSATPPAHLMKLPHIYL
HHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHCCEEEC
PSRYHNRPLPLPKLRYYKITSRSLEQKLKNIVNTTLIFFNDIKQMKKYYAALPESLQAEG
CCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
TIVYSNDDERHDKVEAIRSGEYRFIFTTTILERGFTQENLSVWVINSEQFTWDSLVQIAG
EEEECCCCHHHHHHHHHHCCCEEEEEEHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHH
RVDRKGASMNGEVVFFHEGLSSHMTKAIQTIKRMNKKHDQSMSSV
HHCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLQHITDNANIPSVITKGNKYHCNYCLNDRQYSFHSFYHEGVGKEIVYCRTCLSHYATTE
CCCCCCCCCCCCCEEECCCEEEEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCC
NFIALEPSPKKAEVVTLHLPFELTAQQKRASDYIVRQFRKNQDSLLYAVTGAGKTEMMLQ
CEEEECCCCCCEEEEEEEECCEECHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHH
AVVEARKEGCNVAITAPRTDVVKELALRMQEYMPEIQIDVLYGGHQVLTAGHLIVTTVQQ
HHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCCEEEEEEECCCEEECCCHHHHHHHHH
LIQFNGHFELIIVDEIDAFPMNYDPRLLKVLKRAMHEKGTIIYLSATPPAHLMKLPHIYL
HHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHCCEEEC
PSRYHNRPLPLPKLRYYKITSRSLEQKLKNIVNTTLIFFNDIKQMKKYYAALPESLQAEG
CCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
TIVYSNDDERHDKVEAIRSGEYRFIFTTTILERGFTQENLSVWVINSEQFTWDSLVQIAG
EEEECCCCHHHHHHHHHHCCCEEEEEEHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHH
RVDRKGASMNGEVVFFHEGLSSHMTKAIQTIKRMNKKHDQSMSSV
HHCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8412657; 9384377 [H]