Click here to switch to the map view.

The map label for this gene is tagO [H]

Identifier: 222150746

GI number: 222150746

Start: 525391

End: 526437

Strand: Direct

Name: tagO [H]

Synonym: MCCL_0496

Alternate gene names: 222150746

Gene position: 525391-526437 (Clockwise)

Preceding gene: 222150740

Following gene: 222150748

Centisome position: 24.99

GC content: 37.73

Gene sequence:

>1047_bases
ATGCTCACATTAAAACTAATCATTATAACAGCATTATTCTCTTTCGTACTTACACCTATAATTATCAGATTTTCATACTT
CATTGGCGCTGTCGATAAACCCAATTACCGTAAAGTACATACTAAACCAGTATCGATGCTGGGTGGGGTGATAATCCTAT
GTGCATTTTTGTTCGGTTTATGGATTGGACAGCCAGTTGAAAAAGAAATATATCCAATTATTATCGGTGCGATACTCATA
CAAATAACGGGCCTTATTGATGATTTTATTGATCTTCCGGCCATAATCAAGCTCATTGCACAAATTGGAGTTGCAACAAT
CGTCGTCTATCACGGAATTACGTTAGACTTGATTACTTTACCATTCGGTATCGTAATTGAATTTGGAATTTTTAGTATTC
CGATGACAGTACTATGGATTGTAGCTGTGACAAATGCAATCAATCTTGTTGATGGTCTGGACGGTCTTGCAGCAGGAGTT
TCCGGTATTGCCTTAGCGACGATAGGATTTATCGCCATTATTCAGCAGAATATATTTATCATGATGCTCTGTAGTGTACT
TATCGGAGCATTACTCGGATTTTTGAAATATAACTTTTATCCGGCACGTATCTTTCTTGGAGATAACGGTGCGTTAATGC
TAGGATTTATTATCGGTGTTCTTAGTCTGCTTGGGTTTAAGAATATCACGCTAATTTCTCTATTCTTCCCTGTCATCATC
CTTGCAGTGCCGTTTATCGATATGTCATTTGCAATGATTCGTAGATATAGACAAGGCAAGCCGATCATGCAGGCAGATAA
GTCACATCTGCATCACAAATTACTGCAGCTTGGTTATACGCATCCTCAGACAGTGATACTCATTTATTCAATTGCAGCAC
TGTTTAGCGTTGCCTCAGTCATCTTATATCTATCCTCAGTGTGGGGTGCAATATTAATCGTTCTACTGTTGCTTATCACG
ATTGAATTAATCGTTGAATTTACTGGATTGATAGATGATACCCATCAGCCATTACTCAACTTCATGCGTAGCATTATAAA
GAAATAA

Upstream 100 bases:

>100_bases
TAAATAAAATGCATAGTCAATTGTTACTTATTATATAAATTAATTGATAACATCATTAATTGTGATATTATTAAGAAGAA
TGAATTCAAGAGGTGTACAC

Downstream 100 bases:

>100_bases
CATCTAGAGCATTCTAGATGTTATTTCTGATGTCAAATGGAAGCATCAGTTCAGATTTCACCTGGATAACCGGGGGGCCT
TGTGTGAGTTCTGTAACAAA

Product: lipophilic regulator protein

Products: UMP; Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

Alternate protein names: UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase; Undecaprenyl-Phosphate GlcNAc-1-phosphate transferase [H]

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MLTLKLIIITALFSFVLTPIIIRFSYFIGAVDKPNYRKVHTKPVSMLGGVIILCAFLFGLWIGQPVEKEIYPIIIGAILI
QITGLIDDFIDLPAIIKLIAQIGVATIVVYHGITLDLITLPFGIVIEFGIFSIPMTVLWIVAVTNAINLVDGLDGLAAGV
SGIALATIGFIAIIQQNIFIMMLCSVLIGALLGFLKYNFYPARIFLGDNGALMLGFIIGVLSLLGFKNITLISLFFPVII
LAVPFIDMSFAMIRRYRQGKPIMQADKSHLHHKLLQLGYTHPQTVILIYSIAALFSVASVILYLSSVWGAILIVLLLLIT
IELIVEFTGLIDDTHQPLLNFMRSIIKK

Sequences:

>Translated_348_residues
MLTLKLIIITALFSFVLTPIIIRFSYFIGAVDKPNYRKVHTKPVSMLGGVIILCAFLFGLWIGQPVEKEIYPIIIGAILI
QITGLIDDFIDLPAIIKLIAQIGVATIVVYHGITLDLITLPFGIVIEFGIFSIPMTVLWIVAVTNAINLVDGLDGLAAGV
SGIALATIGFIAIIQQNIFIMMLCSVLIGALLGFLKYNFYPARIFLGDNGALMLGFIIGVLSLLGFKNITLISLFFPVII
LAVPFIDMSFAMIRRYRQGKPIMQADKSHLHHKLLQLGYTHPQTVILIYSIAALFSVASVILYLSSVWGAILIVLLLLIT
IELIVEFTGLIDDTHQPLLNFMRSIIKK
>Mature_348_residues
MLTLKLIIITALFSFVLTPIIIRFSYFIGAVDKPNYRKVHTKPVSMLGGVIILCAFLFGLWIGQPVEKEIYPIIIGAILI
QITGLIDDFIDLPAIIKLIAQIGVATIVVYHGITLDLITLPFGIVIEFGIFSIPMTVLWIVAVTNAINLVDGLDGLAAGV
SGIALATIGFIAIIQQNIFIMMLCSVLIGALLGFLKYNFYPARIFLGDNGALMLGFIIGVLSLLGFKNITLISLFFPVII
LAVPFIDMSFAMIRRYRQGKPIMQADKSHLHHKLLQLGYTHPQTVILIYSIAALFSVASVILYLSSVWGAILIVLLLLIT
IELIVEFTGLIDDTHQPLLNFMRSIIKK

Specific function: Catalyzes the formation of undecaprenyl-PP-N- acetylglucosamine. Involved in the synthesis of anionic cell-wall polymers as it mediates the initiation of the linkage unit formation that appears to be common to the two types of teichoic acids attached to t

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family [H]

Homologues:

Organism=Escherichia coli, GI1790218, Length=273, Percent_Identity=29.6703296703297, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1786275, Length=335, Percent_Identity=27.1641791044776, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: 2.7.8.- [C]

Molecular weight: Translated: 38296; Mature: 38296

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTLKLIIITALFSFVLTPIIIRFSYFIGAVDKPNYRKVHTKPVSMLGGVIILCAFLFGL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHH
WIGQPVEKEIYPIIIGAILIQITGLIDDFIDLPAIIKLIAQIGVATIVVYHGITLDLITL
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
PFGIVIEFGIFSIPMTVLWIVAVTNAINLVDGLDGLAAGVSGIALATIGFIAIIQQNIFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MMLCSVLIGALLGFLKYNFYPARIFLGDNGALMLGFIIGVLSLLGFKNITLISLFFPVII
HHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LAVPFIDMSFAMIRRYRQGKPIMQADKSHLHHKLLQLGYTHPQTVILIYSIAALFSVASV
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
ILYLSSVWGAILIVLLLLITIELIVEFTGLIDDTHQPLLNFMRSIIKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MLTLKLIIITALFSFVLTPIIIRFSYFIGAVDKPNYRKVHTKPVSMLGGVIILCAFLFGL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHH
WIGQPVEKEIYPIIIGAILIQITGLIDDFIDLPAIIKLIAQIGVATIVVYHGITLDLITL
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
PFGIVIEFGIFSIPMTVLWIVAVTNAINLVDGLDGLAAGVSGIALATIGFIAIIQQNIFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MMLCSVLIGALLGFLKYNFYPARIFLGDNGALMLGFIIGVLSLLGFKNITLISLFFPVII
HHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LAVPFIDMSFAMIRRYRQGKPIMQADKSHLHHKLLQLGYTHPQTVILIYSIAALFSVASV
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
ILYLSSVWGAILIVLLLLITIELIVEFTGLIDDTHQPLLNFMRSIIKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-N-Acetyl-D-Glucosamine; Undecaprenyl Phosphate [C]

Specific reaction: UDP-N-Acetyl-D-Glucosamine + Undecaprenyl Phosphate = UMP + Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12101296; 9384377 [H]