| Definition | Macrococcus caseolyticus JCSC5402, complete genome. |
|---|---|
| Accession | NC_011999 |
| Length | 2,102,324 |
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The map label for this gene is fabG [H]
Identifier: 222150662
GI number: 222150662
Start: 438647
End: 439426
Strand: Direct
Name: fabG [H]
Synonym: MCCL_0412
Alternate gene names: 222150662
Gene position: 438647-439426 (Clockwise)
Preceding gene: 222150661
Following gene: 222150663
Centisome position: 20.86
GC content: 41.92
Gene sequence:
>780_bases ATGGATTTAGGTTTAAAGGGTAAAGTAGCTATAATTACAGGTTCAAGTAAAGGCATCGGTAAGGAAACCGCGACGGTATT AGCTGCAGAAGGTGCTCATGTAGTGATTGCTTCTCGTCATGAAGACGAACTGATTGATGTTGCAAAGGAAATTAAGGAGC AGACAGGTCAACAAGTATCTTATCAAGTATGTGATGTTACGAAGGAAACGGACTGTAAACAATTTGTTCAAAAAGCAATC GATACTTACGGAAAGCTTGATATACTCATCAATAATGCAGGAAGTGCGTTTGCTAAAAATTTCGAAGATGTTTCGCTGGA TGACTGGCAGGATGATCTTGACCTCAAACTATTCGGAGCGCTTCATATGTTACATGCAGCATTACCGGAACTTAAGAAGA ATGGGGGCGCCATAGTCAATCTTACAGCCATTGCCGGTAAAAACCCTCCAGCCGATACAACACCAACCTCTGTCACACGT GCAGCAGGACTTGCATTGACCAAGACATTAAGTAAGGATCTTGCACAGTATAATATTCGTGTGAACGCTGTATGTATCGG TCTGATTCGCAGTGGTCAGATTGAAAAACGCTGGCAGGAGGAAGCACCTGAAAAGCCTTGGGAAGAATATGCAAGAGATC CTAAGTTTGAAATTCCGATTGGCCGTATTGGTGATACTAGAGAAGCGGCAAATGTCATTTCATTCTTAGTAAGTGATGCA GCAAGTTATGTTACGGGTACTGCTGTAAATATCGATGGTGGTAAATCACCAAGTCTTTAA
Upstream 100 bases:
>100_bases CAATTAAACCTATCTATTGGATGATAGCACCTTATTGATAAGGTGCATTTTTTTATACTTACTTTAATATTTGTTATGAT GAGAGAAAGGAGCTGAGGAT
Downstream 100 bases:
>100_bases TGAAGATAGCATCAGGAAATATCCTGATGCTATTTTTTTGTCAAAAGGTTGACGAATTCTGTATTGTGTGTATTATATTA TATAGTACAGTTAATACAGT
Product: hypothetical protein
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 259; Mature: 259
Protein sequence:
>259_residues MDLGLKGKVAIITGSSKGIGKETATVLAAEGAHVVIASRHEDELIDVAKEIKEQTGQQVSYQVCDVTKETDCKQFVQKAI DTYGKLDILINNAGSAFAKNFEDVSLDDWQDDLDLKLFGALHMLHAALPELKKNGGAIVNLTAIAGKNPPADTTPTSVTR AAGLALTKTLSKDLAQYNIRVNAVCIGLIRSGQIEKRWQEEAPEKPWEEYARDPKFEIPIGRIGDTREAANVISFLVSDA ASYVTGTAVNIDGGKSPSL
Sequences:
>Translated_259_residues MDLGLKGKVAIITGSSKGIGKETATVLAAEGAHVVIASRHEDELIDVAKEIKEQTGQQVSYQVCDVTKETDCKQFVQKAI DTYGKLDILINNAGSAFAKNFEDVSLDDWQDDLDLKLFGALHMLHAALPELKKNGGAIVNLTAIAGKNPPADTTPTSVTR AAGLALTKTLSKDLAQYNIRVNAVCIGLIRSGQIEKRWQEEAPEKPWEEYARDPKFEIPIGRIGDTREAANVISFLVSDA ASYVTGTAVNIDGGKSPSL >Mature_259_residues MDLGLKGKVAIITGSSKGIGKETATVLAAEGAHVVIASRHEDELIDVAKEIKEQTGQQVSYQVCDVTKETDCKQFVQKAI DTYGKLDILINNAGSAFAKNFEDVSLDDWQDDLDLKLFGALHMLHAALPELKKNGGAIVNLTAIAGKNPPADTTPTSVTR AAGLALTKTLSKDLAQYNIRVNAVCIGLIRSGQIEKRWQEEAPEKPWEEYARDPKFEIPIGRIGDTREAANVISFLVSDA ASYVTGTAVNIDGGKSPSL
Specific function: 7-Alpha-Dehydroxylation Of Cholic Acid, Yielding Deoxycholic Acid And Lithocholic Acid, Respectively. Highest Affinity With Taurochenodeoxycholic Acid. [C]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=256, Percent_Identity=36.71875, Blast_Score=151, Evalue=5e-37, Organism=Homo sapiens, GI19923817, Length=258, Percent_Identity=33.3333333333333, Blast_Score=134, Evalue=9e-32, Organism=Homo sapiens, GI126723750, Length=259, Percent_Identity=33.5907335907336, Blast_Score=128, Evalue=5e-30, Organism=Homo sapiens, GI5031737, Length=250, Percent_Identity=33.2, Blast_Score=121, Evalue=5e-28, Organism=Homo sapiens, GI4503301, Length=253, Percent_Identity=32.0158102766798, Blast_Score=108, Evalue=3e-24, Organism=Homo sapiens, GI126723191, Length=188, Percent_Identity=36.1702127659575, Blast_Score=108, Evalue=5e-24, Organism=Homo sapiens, GI66933014, Length=255, Percent_Identity=32.5490196078431, Blast_Score=104, Evalue=6e-23, Organism=Homo sapiens, GI10190704, Length=251, Percent_Identity=29.8804780876494, Blast_Score=103, Evalue=1e-22, Organism=Homo sapiens, GI59889578, Length=232, Percent_Identity=31.4655172413793, Blast_Score=103, Evalue=1e-22, Organism=Homo sapiens, GI33667109, Length=188, Percent_Identity=35.1063829787234, Blast_Score=100, Evalue=1e-21, Organism=Homo sapiens, GI15277342, Length=260, Percent_Identity=27.6923076923077, Blast_Score=97, Evalue=2e-20, Organism=Homo sapiens, GI7705925, Length=256, Percent_Identity=27.34375, Blast_Score=96, Evalue=3e-20, Organism=Homo sapiens, GI40254992, Length=248, Percent_Identity=27.0161290322581, Blast_Score=96, Evalue=4e-20, Organism=Homo sapiens, GI31542939, Length=246, Percent_Identity=27.6422764227642, Blast_Score=93, Evalue=3e-19, Organism=Homo sapiens, GI32455239, Length=194, Percent_Identity=30.4123711340206, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI5031765, Length=194, Percent_Identity=30.4123711340206, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI4758504, Length=263, Percent_Identity=25.8555133079848, Blast_Score=81, Evalue=7e-16, Organism=Homo sapiens, GI20149619, Length=193, Percent_Identity=29.0155440414508, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI4503817, Length=185, Percent_Identity=26.4864864864865, Blast_Score=75, Evalue=4e-14, Organism=Homo sapiens, GI224922801, Length=172, Percent_Identity=27.3255813953488, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI157739938, Length=199, Percent_Identity=28.1407035175879, Blast_Score=75, Evalue=8e-14, Organism=Homo sapiens, GI109715829, Length=215, Percent_Identity=27.4418604651163, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI83715985, Length=263, Percent_Identity=25.0950570342205, Blast_Score=71, Evalue=8e-13, Organism=Homo sapiens, GI302344755, Length=114, Percent_Identity=35.0877192982456, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI209862901, Length=211, Percent_Identity=26.5402843601896, Blast_Score=68, Evalue=7e-12, Organism=Homo sapiens, GI19923983, Length=211, Percent_Identity=26.5402843601896, Blast_Score=68, Evalue=7e-12, Organism=Homo sapiens, GI193804850, Length=113, Percent_Identity=36.283185840708, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI7706318, Length=196, Percent_Identity=26.0204081632653, Blast_Score=65, Evalue=4e-11, Organism=Escherichia coli, GI1787905, Length=254, Percent_Identity=34.6456692913386, Blast_Score=140, Evalue=1e-34, Organism=Escherichia coli, GI87082100, Length=261, Percent_Identity=33.7164750957854, Blast_Score=133, Evalue=1e-32, Organism=Escherichia coli, GI1788459, Length=251, Percent_Identity=31.4741035856574, Blast_Score=110, Evalue=9e-26, Organism=Escherichia coli, GI87082160, Length=261, Percent_Identity=30.6513409961686, Blast_Score=107, Evalue=9e-25, Organism=Escherichia coli, GI1787335, Length=253, Percent_Identity=26.4822134387352, Blast_Score=106, Evalue=2e-24, Organism=Escherichia coli, GI1789057, Length=257, Percent_Identity=28.0155642023346, Blast_Score=103, Evalue=1e-23, Organism=Escherichia coli, GI1789208, Length=256, Percent_Identity=26.5625, Blast_Score=95, Evalue=4e-21, Organism=Escherichia coli, GI1786812, Length=255, Percent_Identity=27.843137254902, Blast_Score=94, Evalue=8e-21, Organism=Escherichia coli, GI1789378, Length=257, Percent_Identity=29.5719844357977, Blast_Score=90, Evalue=1e-19, Organism=Escherichia coli, GI2367175, Length=254, Percent_Identity=30.3149606299213, Blast_Score=87, Evalue=1e-18, Organism=Escherichia coli, GI1790717, Length=253, Percent_Identity=26.4822134387352, Blast_Score=84, Evalue=1e-17, Organism=Escherichia coli, GI1787526, Length=205, Percent_Identity=27.3170731707317, Blast_Score=79, Evalue=2e-16, Organism=Escherichia coli, GI1787820, Length=183, Percent_Identity=25.6830601092896, Blast_Score=70, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17562910, Length=258, Percent_Identity=34.1085271317829, Blast_Score=133, Evalue=1e-31, Organism=Caenorhabditis elegans, GI17559104, Length=257, Percent_Identity=34.6303501945525, Blast_Score=131, Evalue=4e-31, Organism=Caenorhabditis elegans, GI17562904, Length=261, Percent_Identity=32.9501915708812, Blast_Score=129, Evalue=1e-30, Organism=Caenorhabditis elegans, GI17560332, Length=260, Percent_Identity=35, Blast_Score=121, Evalue=4e-28, Organism=Caenorhabditis elegans, GI17562906, Length=261, Percent_Identity=32.183908045977, Blast_Score=121, Evalue=4e-28, Organism=Caenorhabditis elegans, GI17560676, Length=252, Percent_Identity=31.7460317460317, Blast_Score=120, Evalue=6e-28, Organism=Caenorhabditis elegans, GI17560150, Length=258, Percent_Identity=31.0077519379845, Blast_Score=117, Evalue=6e-27, Organism=Caenorhabditis elegans, GI71994600, Length=250, Percent_Identity=30, Blast_Score=116, Evalue=1e-26, Organism=Caenorhabditis elegans, GI17531453, Length=264, Percent_Identity=32.1969696969697, Blast_Score=115, Evalue=3e-26, Organism=Caenorhabditis elegans, GI17561402, Length=260, Percent_Identity=32.3076923076923, Blast_Score=114, Evalue=3e-26, Organism=Caenorhabditis elegans, GI17562990, Length=258, Percent_Identity=29.8449612403101, Blast_Score=112, Evalue=1e-25, Organism=Caenorhabditis elegans, GI71994604, Length=249, Percent_Identity=28.5140562248996, Blast_Score=110, Evalue=5e-25, Organism=Caenorhabditis elegans, GI25147288, Length=259, Percent_Identity=30.8880308880309, Blast_Score=110, Evalue=8e-25, Organism=Caenorhabditis elegans, GI17562908, Length=264, Percent_Identity=29.5454545454545, Blast_Score=108, Evalue=4e-24, Organism=Caenorhabditis elegans, GI17538480, Length=262, Percent_Identity=30.1526717557252, Blast_Score=104, Evalue=4e-23, Organism=Caenorhabditis elegans, GI17536025, Length=258, Percent_Identity=31.0077519379845, Blast_Score=104, Evalue=5e-23, Organism=Caenorhabditis elegans, GI17560220, Length=260, Percent_Identity=29.6153846153846, Blast_Score=103, Evalue=7e-23, Organism=Caenorhabditis elegans, GI72000259, Length=258, Percent_Identity=29.8449612403101, Blast_Score=103, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17536651, Length=257, Percent_Identity=29.5719844357977, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17544670, Length=261, Percent_Identity=29.5019157088123, Blast_Score=101, Evalue=3e-22, Organism=Caenorhabditis elegans, GI17538486, Length=260, Percent_Identity=33.0769230769231, Blast_Score=101, Evalue=4e-22, Organism=Caenorhabditis elegans, GI193204405, Length=261, Percent_Identity=28.3524904214559, Blast_Score=101, Evalue=4e-22, Organism=Caenorhabditis elegans, GI17551412, Length=264, Percent_Identity=28.030303030303, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17555706, Length=252, Percent_Identity=29.3650793650794, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17563726, Length=258, Percent_Identity=30.2325581395349, Blast_Score=98, Evalue=4e-21, Organism=Caenorhabditis elegans, GI17561272, Length=263, Percent_Identity=31.5589353612167, Blast_Score=96, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17565030, Length=261, Percent_Identity=30.2681992337165, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI115534694, Length=252, Percent_Identity=27.3809523809524, Blast_Score=87, Evalue=7e-18, Organism=Caenorhabditis elegans, GI17538182, Length=262, Percent_Identity=27.4809160305344, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17568967, Length=199, Percent_Identity=31.6582914572864, Blast_Score=77, Evalue=9e-15, Organism=Caenorhabditis elegans, GI17508895, Length=261, Percent_Identity=26.8199233716475, Blast_Score=74, Evalue=6e-14, Organism=Caenorhabditis elegans, GI71997402, Length=145, Percent_Identity=31.7241379310345, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17508651, Length=252, Percent_Identity=26.1904761904762, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17567345, Length=144, Percent_Identity=29.1666666666667, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI71982365, Length=150, Percent_Identity=32, Blast_Score=67, Evalue=8e-12, Organism=Caenorhabditis elegans, GI17557780, Length=226, Percent_Identity=27.4336283185841, Blast_Score=65, Evalue=2e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=253, Percent_Identity=28.4584980237154, Blast_Score=97, Evalue=2e-21, Organism=Saccharomyces cerevisiae, GI6323882, Length=213, Percent_Identity=30.0469483568075, Blast_Score=82, Evalue=6e-17, Organism=Saccharomyces cerevisiae, GI6322226, Length=140, Percent_Identity=34.2857142857143, Blast_Score=81, Evalue=1e-16, Organism=Saccharomyces cerevisiae, GI6322861, Length=204, Percent_Identity=30.8823529411765, Blast_Score=76, Evalue=4e-15, Organism=Drosophila melanogaster, GI23397609, Length=253, Percent_Identity=33.9920948616601, Blast_Score=132, Evalue=2e-31, Organism=Drosophila melanogaster, GI28571526, Length=251, Percent_Identity=33.4661354581673, Blast_Score=130, Evalue=1e-30, Organism=Drosophila melanogaster, GI24644339, Length=253, Percent_Identity=31.6205533596838, Blast_Score=129, Evalue=1e-30, Organism=Drosophila melanogaster, GI21357041, Length=251, Percent_Identity=30.2788844621514, Blast_Score=126, Evalue=1e-29, Organism=Drosophila melanogaster, GI21355319, Length=257, Percent_Identity=33.0739299610895, Blast_Score=121, Evalue=5e-28, Organism=Drosophila melanogaster, GI24643142, Length=257, Percent_Identity=29.1828793774319, Blast_Score=103, Evalue=1e-22, Organism=Drosophila melanogaster, GI24639444, Length=260, Percent_Identity=29.6153846153846, Blast_Score=100, Evalue=2e-21, Organism=Drosophila melanogaster, GI24644337, Length=254, Percent_Identity=30.7086614173228, Blast_Score=97, Evalue=9e-21, Organism=Drosophila melanogaster, GI17737361, Length=263, Percent_Identity=28.1368821292776, Blast_Score=90, Evalue=2e-18, Organism=Drosophila melanogaster, GI161076933, Length=186, Percent_Identity=31.7204301075269, Blast_Score=83, Evalue=2e-16, Organism=Drosophila melanogaster, GI24584748, Length=185, Percent_Identity=30.2702702702703, Blast_Score=83, Evalue=2e-16, Organism=Drosophila melanogaster, GI21358495, Length=191, Percent_Identity=28.7958115183246, Blast_Score=81, Evalue=7e-16, Organism=Drosophila melanogaster, GI21356301, Length=181, Percent_Identity=29.8342541436464, Blast_Score=79, Evalue=3e-15, Organism=Drosophila melanogaster, GI45553409, Length=203, Percent_Identity=30.0492610837438, Blast_Score=75, Evalue=6e-14, Organism=Drosophila melanogaster, GI24647948, Length=203, Percent_Identity=30.0492610837438, Blast_Score=75, Evalue=6e-14, Organism=Drosophila melanogaster, GI24647946, Length=202, Percent_Identity=29.7029702970297, Blast_Score=74, Evalue=9e-14, Organism=Drosophila melanogaster, GI18859837, Length=192, Percent_Identity=27.6041666666667, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI24640492, Length=175, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI24584744, Length=188, Percent_Identity=30.8510638297872, Blast_Score=71, Evalue=6e-13, Organism=Drosophila melanogaster, GI28574402, Length=188, Percent_Identity=30.8510638297872, Blast_Score=71, Evalue=7e-13, Organism=Drosophila melanogaster, GI24649181, Length=191, Percent_Identity=25.130890052356, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI21357673, Length=159, Percent_Identity=30.8176100628931, Blast_Score=68, Evalue=7e-12, Organism=Drosophila melanogaster, GI28571387, Length=160, Percent_Identity=29.375, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI281364892, Length=178, Percent_Identity=27.5280898876405, Blast_Score=65, Evalue=3e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 27821; Mature: 27821
Theoretical pI: Translated: 5.03; Mature: 5.03
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 0.8 %Met (Translated Protein) 1.9 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 0.8 %Met (Mature Protein) 1.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDLGLKGKVAIITGSSKGIGKETATVLAAEGAHVVIASRHEDELIDVAKEIKEQTGQQVS CCCCCCCEEEEEECCCCCCCCHHHEEEEECCCEEEEECCCCHHHHHHHHHHHHHCCCEEE YQVCDVTKETDCKQFVQKAIDTYGKLDILINNAGSAFAKNFEDVSLDDWQDDLDLKLFGA EHHHCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCHHHCCCCCCCCCCCCCCCCHHHHHH LHMLHAALPELKKNGGAIVNLTAIAGKNPPADTTPTSVTRAAGLALTKTLSKDLAQYNIR HHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCEE VNAVCIGLIRSGQIEKRWQEEAPEKPWEEYARDPKFEIPIGRIGDTREAANVISFLVSDA EEEEEEEEHHCCCHHHHHHHHCCCCCHHHHHCCCCEECCCCCCCCHHHHHHHHHHHHHHH ASYVTGTAVNIDGGKSPSL HHHHCCEEEEECCCCCCCC >Mature Secondary Structure MDLGLKGKVAIITGSSKGIGKETATVLAAEGAHVVIASRHEDELIDVAKEIKEQTGQQVS CCCCCCCEEEEEECCCCCCCCHHHEEEEECCCEEEEECCCCHHHHHHHHHHHHHCCCEEE YQVCDVTKETDCKQFVQKAIDTYGKLDILINNAGSAFAKNFEDVSLDDWQDDLDLKLFGA EHHHCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCHHHCCCCCCCCCCCCCCCCHHHHHH LHMLHAALPELKKNGGAIVNLTAIAGKNPPADTTPTSVTRAAGLALTKTLSKDLAQYNIR HHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCEE VNAVCIGLIRSGQIEKRWQEEAPEKPWEEYARDPKFEIPIGRIGDTREAANVISFLVSDA EEEEEEEEHHCCCHHHHHHHHCCCCCHHHHHCCCCEECCCCCCCCHHHHHHHHHHHHHHH ASYVTGTAVNIDGGKSPSL HHHHCCEEEEECCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 10360571 [H]