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The map label for this gene is scrR [H]

Identifier: 222150622

GI number: 222150622

Start: 396081

End: 397049

Strand: Direct

Name: scrR [H]

Synonym: MCCL_0372

Alternate gene names: 222150622

Gene position: 396081-397049 (Clockwise)

Preceding gene: 222150621

Following gene: 222150623

Centisome position: 18.84

GC content: 38.91

Gene sequence:

>969_bases
ATGAATATTCATGATATCGCAAAGATTGCAGGCGTATCAAAGAGCACTGTTTCACGTTATTTAAATGGTGGATCAATCAG
TCAGAGAACACGAGACAAAATAGATAAGGTTGTAAAAGAAACAGGTTATGCACCTAATCAATTTGCACAAAGTTTAAAAG
CGAAACGTACACAGATGATTGGTGTCATTGTGCCTAGATTAAATTCATTTGCTTCAAATGAGACATTGCTTGGTATTGAA
ACCTATTTAAGACAGCAGCATCATCAGACAATCATCGTAAATACAGATCTTGATGTAACACTGGAAATTAATGCGCTCTA
TTCATTAGCGAAAAATAAGGTCGACGGTATCCTGCTCTTTGCGACTCAAATCACCGATGAACATCTTAAAGCGTTTGACA
CAATTGCGACACCAGTTATATTGGTAGGGCAGTCCTATAGAGGCTTACATTCCATTGTACAAAACGATTATGAAGCGGGT
CTTGCTATCGGTGAATACTTTGGAAAGACATCTTTATCTCGCATTGCATATCTGGGTGTAGGGGAATATGACAAAGCAGT
CGGCATCCATCGTAAGAATGGTGTGTTAGAAGGTTTGAAGCACTTTAATAAAGTGGCTGATGATTACGAAACAACATTTA
AGTTATCTGATGCTAAAGAACGTGCAAAGCAGCTGCTGTCAGCATATGATGCAGTTATCTGTGCGACAGATAATATCGCA
CTTGGTGTATTGAAAGCTGCTTATGATTTAGACATAAAAGTACCTGAGCAACTATCGATCAGTGGATTCGGTGGATATGA
GACAACATCGATTGTCACACCGATGATTACAACTGTAGCATTCCCATACCAGCGGACAGGAAAGTGTGCTGCAGCATCAA
TGTTAGCCTTACTAGAAGGTAAGGATATCCCTTATTTACAGCGCATGGATTTCCAAATTATCGAAAAAGAAAGCGTTGAC
ATTTATTGA

Upstream 100 bases:

>100_bases
TATTTTGATTCTGAAAGTGGATTATTGATTAAATGAACGAGTGACTATGTGTTTATTTTAAAGGATGAATATATGCTATT
ATTATCAAGAGGTGAAGGCC

Downstream 100 bases:

>100_bases
ACGTAAGCGTAAAATGCTCATTAAGAAGCATTTTACTTTTTTTTAGACATAAATGGAACCGGTTCCAAAGGAGTGAGGAC
ATGGAATGGACGCGTGAAAT

Product: hypothetical protein

Products: NA

Alternate protein names: Scr operon regulatory protein [H]

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MNIHDIAKIAGVSKSTVSRYLNGGSISQRTRDKIDKVVKETGYAPNQFAQSLKAKRTQMIGVIVPRLNSFASNETLLGIE
TYLRQQHHQTIIVNTDLDVTLEINALYSLAKNKVDGILLFATQITDEHLKAFDTIATPVILVGQSYRGLHSIVQNDYEAG
LAIGEYFGKTSLSRIAYLGVGEYDKAVGIHRKNGVLEGLKHFNKVADDYETTFKLSDAKERAKQLLSAYDAVICATDNIA
LGVLKAAYDLDIKVPEQLSISGFGGYETTSIVTPMITTVAFPYQRTGKCAAASMLALLEGKDIPYLQRMDFQIIEKESVD
IY

Sequences:

>Translated_322_residues
MNIHDIAKIAGVSKSTVSRYLNGGSISQRTRDKIDKVVKETGYAPNQFAQSLKAKRTQMIGVIVPRLNSFASNETLLGIE
TYLRQQHHQTIIVNTDLDVTLEINALYSLAKNKVDGILLFATQITDEHLKAFDTIATPVILVGQSYRGLHSIVQNDYEAG
LAIGEYFGKTSLSRIAYLGVGEYDKAVGIHRKNGVLEGLKHFNKVADDYETTFKLSDAKERAKQLLSAYDAVICATDNIA
LGVLKAAYDLDIKVPEQLSISGFGGYETTSIVTPMITTVAFPYQRTGKCAAASMLALLEGKDIPYLQRMDFQIIEKESVD
IY
>Mature_322_residues
MNIHDIAKIAGVSKSTVSRYLNGGSISQRTRDKIDKVVKETGYAPNQFAQSLKAKRTQMIGVIVPRLNSFASNETLLGIE
TYLRQQHHQTIIVNTDLDVTLEINALYSLAKNKVDGILLFATQITDEHLKAFDTIATPVILVGQSYRGLHSIVQNDYEAG
LAIGEYFGKTSLSRIAYLGVGEYDKAVGIHRKNGVLEGLKHFNKVADDYETTFKLSDAKERAKQLLSAYDAVICATDNIA
LGVLKAAYDLDIKVPEQLSISGFGGYETTSIVTPMITTVAFPYQRTGKCAAASMLALLEGKDIPYLQRMDFQIIEKESVD
IY

Specific function: Negative regulator of scrB expression [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790194, Length=299, Percent_Identity=29.0969899665552, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1790689, Length=311, Percent_Identity=28.6173633440514, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI48994940, Length=319, Percent_Identity=26.6457680250784, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1790715, Length=311, Percent_Identity=26.3665594855305, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1789068, Length=328, Percent_Identity=25.3048780487805, Blast_Score=104, Evalue=9e-24,
Organism=Escherichia coli, GI1787580, Length=319, Percent_Identity=28.2131661442006, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1787948, Length=329, Percent_Identity=24.6200607902736, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI1790369, Length=326, Percent_Identity=26.0736196319018, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1786268, Length=321, Percent_Identity=25.8566978193146, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788474, Length=302, Percent_Identity=28.476821192053, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786540, Length=328, Percent_Identity=23.4756097560976, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1787906, Length=315, Percent_Identity=26.984126984127, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1789202, Length=290, Percent_Identity=24.4827586206897, Blast_Score=75, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 35495; Mature: 35495

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHDIAKIAGVSKSTVSRYLNGGSISQRTRDKIDKVVKETGYAPNQFAQSLKAKRTQMI
CCHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
GVIVPRLNSFASNETLLGIETYLRQQHHQTIIVNTDLDVTLEINALYSLAKNKVDGILLF
HHHHHHHHCCCCCCEEEHHHHHHHHHCCCEEEEECCCEEEEEHHHHHHHHHCCCCEEEEE
ATQITDEHLKAFDTIATPVILVGQSYRGLHSIVQNDYEAGLAIGEYFGKTSLSRIAYLGV
EEHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHCHHHHHHHHHHHHCCHHHHHEEEECC
GEYDKAVGIHRKNGVLEGLKHFNKVADDYETTFKLSDAKERAKQLLSAYDAVICATDNIA
CCCHHHHCCCHHCCHHHHHHHHHHHHCCHHHEEEECHHHHHHHHHHHHHHEEEEECCCHH
LGVLKAAYDLDIKVPEQLSISGFGGYETTSIVTPMITTVAFPYQRTGKCAAASMLALLEG
HHHHHHHHCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHCC
KDIPYLQRMDFQIIEKESVDIY
CCCCHHHHCCHHEEECCCCCCC
>Mature Secondary Structure
MNIHDIAKIAGVSKSTVSRYLNGGSISQRTRDKIDKVVKETGYAPNQFAQSLKAKRTQMI
CCHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
GVIVPRLNSFASNETLLGIETYLRQQHHQTIIVNTDLDVTLEINALYSLAKNKVDGILLF
HHHHHHHHCCCCCCEEEHHHHHHHHHCCCEEEEECCCEEEEEHHHHHHHHHCCCCEEEEE
ATQITDEHLKAFDTIATPVILVGQSYRGLHSIVQNDYEAGLAIGEYFGKTSLSRIAYLGV
EEHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHCHHHHHHHHHHHHCCHHHHHEEEECC
GEYDKAVGIHRKNGVLEGLKHFNKVADDYETTFKLSDAKERAKQLLSAYDAVICATDNIA
CCCHHHHCCCHHCCHHHHHHHHHHHHCCHHHEEEECHHHHHHHHHHHHHHEEEEECCCHH
LGVLKAAYDLDIKVPEQLSISGFGGYETTSIVTPMITTVAFPYQRTGKCAAASMLALLEG
HHHHHHHHCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHCC
KDIPYLQRMDFQIIEKESVDIY
CCCCHHHHCCHHEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8550467 [H]