Click here to switch to the map view.

The map label for this gene is yugT [H]

Identifier: 222150612

GI number: 222150612

Start: 378986

End: 380644

Strand: Direct

Name: yugT [H]

Synonym: MCCL_0362

Alternate gene names: 222150612

Gene position: 378986-380644 (Clockwise)

Preceding gene: 222150611

Following gene: 222150614

Centisome position: 18.03

GC content: 33.03

Gene sequence:

>1659_bases
ATGAAAAAGCAATGGTGGAAAGAAGCCGTTTGTTATCAAGTGTATCCAAGAAGTTTTAAAGATTCTAATGGTGATGGCAT
AGGGGATATTAATGGTATAACAGAAAAGTTAGATTATCTAAAAGATTTAGGGATTGATGTGATTTGGATTTCTCCAATAT
ATGATTCTCCTAATGATGATAACGGATATGATATTAGCGACTACCAAAATATTATGAGTGATTTTGGAACTATGGAAGAT
TTTGACCGTCTTTTAATAGAAACTCATAATAGAGATATGAAGCTCATAATGGATTTAGTTGTAAATCATACTAGTGATGA
GCATCCGTGGTTTATTGAATCAAGATCGTCTGTTGATTCTGAATATAGAGATTGGTATATTTGGCAGGATGGTAAAGAAG
GGAAGGAACCAAATAACTGGGCAAGCATATTTGAAGGTTCAGCATGGGAACTTGATCCTGTTTCAAATCAATATTACTTC
CATACCTTCAGTAGAAAGCAACCAGATTTGAACTGGGATAACCAAAAGATGCGTCAATCGATATATAATATGATAAATTG
GTGGCTTGATAAAGGTATTGATGGTTTTAGAGTAGATGCAATTAGTCATATTAAGAAGTCATTTGATAAAGGTGACATAG
ACAACCCTGATAATCTAGACTATGTACCATCATTTACTCGACATATGAATCAACCGGGTATTCAAGAGTATCTTGAGGAA
GTAAAAGAAGAAACATTTAGTAAGTACGACATTATGACGGTTGGAGAAGCTAATGGTGTAACAATCGAAGATTCATATGA
ATGGGTCGGGGAAGAAGTCGGGAAGTTTAATATGGTATTTCAGTTTGAACACTTAAAGTTATGGGAGATTCATGATAAAC
GACTTAACATATTGAAATATAAAAATGTATTAAATGATTGGCAAGTAGGTCTTCATAACAAAGGATGGAATGCATTATTT
ATTGAAAATCATGATCGTCCAAGAATACCTTCAACCTGGGGTTCGGAAAATTATAGATATGAAAGTGCTACAGCACACGG
GGCAGTTTATTTTTTACAGCAGGGTACGCCATTTATTTATCAAGGTCAGGAAATAGGTATGACGAATTTTCCATTTAAGG
ATATTTCGGAATTTGATGATGTACATGCGAAAAATATTTATAATGTGGAATTAGCAAATGGCAGAAACGCAGATGATATT
ATTGCAGACCTACAATCGAATTCAAGAGATAATTCAAGAACACCGATGCAATGGGATGCTTCTGAGAATGCGGGATTTAC
AAATGGGACACCTTGGTTAAAAGTAAATCCAAATTACAAAGCAATAAATGTTGAAAAGGAATTAAACGATGAGAATTCAA
TACTGAATTTTTATAAGAAGATGATTAAATTTAAGAAATCACATGAAATAGCTACTTATGGAGATTTCAAATTAATATAT
CCTGAAGATGAAAATGTATTTGCTTATGCTAGAACTTTAAATGATGAGTTACTTTACGTTATTGGAAACCTCACTTCAAA
CCCTGTTAAAGTTTCTGATAGCCAAATTGAGTTTGATTCATCTGATATTGTATTGAATAACTATGATATAGAAAGTCATC
GTAGACAAAAAACACTGGATCTTAAGCCATTTGAGGTTAGAGTTTATCACAAAGGTTAG

Upstream 100 bases:

>100_bases
TTTGATATGAATAAAGCACACTTCTTTGATGTTGATACGACAATTAGAATAAAAAATTAATCTCATATAATAATATTATA
GATAAGTCGAGGAGTTTGTA

Downstream 100 bases:

>100_bases
ATATGTATAGTTATTAATATAAAAACTTAAGTCACTTTAAATCGTCTACACTTAATTGGACAACTCCCCTGAGGGGATAT
ATTGTTAAATTAAGAAAGTA

Product: alpha-glucosidase

Products: NA

Alternate protein names: Oligosaccharide alpha-1,6-glucosidase 3; Sucrase-isomaltase 3; Isomaltase 3 [H]

Number of amino acids: Translated: 552; Mature: 552

Protein sequence:

>552_residues
MKKQWWKEAVCYQVYPRSFKDSNGDGIGDINGITEKLDYLKDLGIDVIWISPIYDSPNDDNGYDISDYQNIMSDFGTMED
FDRLLIETHNRDMKLIMDLVVNHTSDEHPWFIESRSSVDSEYRDWYIWQDGKEGKEPNNWASIFEGSAWELDPVSNQYYF
HTFSRKQPDLNWDNQKMRQSIYNMINWWLDKGIDGFRVDAISHIKKSFDKGDIDNPDNLDYVPSFTRHMNQPGIQEYLEE
VKEETFSKYDIMTVGEANGVTIEDSYEWVGEEVGKFNMVFQFEHLKLWEIHDKRLNILKYKNVLNDWQVGLHNKGWNALF
IENHDRPRIPSTWGSENYRYESATAHGAVYFLQQGTPFIYQGQEIGMTNFPFKDISEFDDVHAKNIYNVELANGRNADDI
IADLQSNSRDNSRTPMQWDASENAGFTNGTPWLKVNPNYKAINVEKELNDENSILNFYKKMIKFKKSHEIATYGDFKLIY
PEDENVFAYARTLNDELLYVIGNLTSNPVKVSDSQIEFDSSDIVLNNYDIESHRRQKTLDLKPFEVRVYHKG

Sequences:

>Translated_552_residues
MKKQWWKEAVCYQVYPRSFKDSNGDGIGDINGITEKLDYLKDLGIDVIWISPIYDSPNDDNGYDISDYQNIMSDFGTMED
FDRLLIETHNRDMKLIMDLVVNHTSDEHPWFIESRSSVDSEYRDWYIWQDGKEGKEPNNWASIFEGSAWELDPVSNQYYF
HTFSRKQPDLNWDNQKMRQSIYNMINWWLDKGIDGFRVDAISHIKKSFDKGDIDNPDNLDYVPSFTRHMNQPGIQEYLEE
VKEETFSKYDIMTVGEANGVTIEDSYEWVGEEVGKFNMVFQFEHLKLWEIHDKRLNILKYKNVLNDWQVGLHNKGWNALF
IENHDRPRIPSTWGSENYRYESATAHGAVYFLQQGTPFIYQGQEIGMTNFPFKDISEFDDVHAKNIYNVELANGRNADDI
IADLQSNSRDNSRTPMQWDASENAGFTNGTPWLKVNPNYKAINVEKELNDENSILNFYKKMIKFKKSHEIATYGDFKLIY
PEDENVFAYARTLNDELLYVIGNLTSNPVKVSDSQIEFDSSDIVLNNYDIESHRRQKTLDLKPFEVRVYHKG
>Mature_552_residues
MKKQWWKEAVCYQVYPRSFKDSNGDGIGDINGITEKLDYLKDLGIDVIWISPIYDSPNDDNGYDISDYQNIMSDFGTMED
FDRLLIETHNRDMKLIMDLVVNHTSDEHPWFIESRSSVDSEYRDWYIWQDGKEGKEPNNWASIFEGSAWELDPVSNQYYF
HTFSRKQPDLNWDNQKMRQSIYNMINWWLDKGIDGFRVDAISHIKKSFDKGDIDNPDNLDYVPSFTRHMNQPGIQEYLEE
VKEETFSKYDIMTVGEANGVTIEDSYEWVGEEVGKFNMVFQFEHLKLWEIHDKRLNILKYKNVLNDWQVGLHNKGWNALF
IENHDRPRIPSTWGSENYRYESATAHGAVYFLQQGTPFIYQGQEIGMTNFPFKDISEFDDVHAKNIYNVELANGRNADDI
IADLQSNSRDNSRTPMQWDASENAGFTNGTPWLKVNPNYKAINVEKELNDENSILNFYKKMIKFKKSHEIATYGDFKLIY
PEDENVFAYARTLNDELLYVIGNLTSNPVKVSDSQIEFDSSDIVLNNYDIESHRRQKTLDLKPFEVRVYHKG

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=520, Percent_Identity=30.9615384615385, Blast_Score=239, Evalue=4e-63,
Organism=Escherichia coli, GI1790687, Length=551, Percent_Identity=39.3829401088929, Blast_Score=430, Evalue=1e-121,
Organism=Escherichia coli, GI1786604, Length=523, Percent_Identity=22.1797323135755, Blast_Score=102, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI32565753, Length=375, Percent_Identity=29.0666666666667, Blast_Score=129, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI25147709, Length=575, Percent_Identity=24.1739130434783, Blast_Score=112, Evalue=7e-25,
Organism=Saccharomyces cerevisiae, GI6324416, Length=582, Percent_Identity=39.0034364261168, Blast_Score=369, Evalue=1e-103,
Organism=Saccharomyces cerevisiae, GI6322241, Length=582, Percent_Identity=38.8316151202749, Blast_Score=365, Evalue=1e-102,
Organism=Saccharomyces cerevisiae, GI6322021, Length=582, Percent_Identity=38.8316151202749, Blast_Score=365, Evalue=1e-102,
Organism=Saccharomyces cerevisiae, GI6321726, Length=583, Percent_Identity=38.2504288164666, Blast_Score=365, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6322245, Length=579, Percent_Identity=36.0967184801382, Blast_Score=350, Evalue=3e-97,
Organism=Saccharomyces cerevisiae, GI6319776, Length=581, Percent_Identity=38.382099827883, Blast_Score=347, Evalue=2e-96,
Organism=Saccharomyces cerevisiae, GI6321731, Length=581, Percent_Identity=38.209982788296, Blast_Score=347, Evalue=3e-96,
Organism=Drosophila melanogaster, GI24583745, Length=575, Percent_Identity=33.9130434782609, Blast_Score=290, Evalue=2e-78,
Organism=Drosophila melanogaster, GI24586599, Length=579, Percent_Identity=33.8514680483592, Blast_Score=281, Evalue=6e-76,
Organism=Drosophila melanogaster, GI221330053, Length=558, Percent_Identity=33.5125448028674, Blast_Score=281, Evalue=9e-76,
Organism=Drosophila melanogaster, GI24583749, Length=518, Percent_Identity=36.1003861003861, Blast_Score=276, Evalue=2e-74,
Organism=Drosophila melanogaster, GI24583747, Length=518, Percent_Identity=36.1003861003861, Blast_Score=276, Evalue=2e-74,
Organism=Drosophila melanogaster, GI24586593, Length=535, Percent_Identity=33.0841121495327, Blast_Score=270, Evalue=2e-72,
Organism=Drosophila melanogaster, GI24586589, Length=513, Percent_Identity=34.1130604288499, Blast_Score=266, Evalue=4e-71,
Organism=Drosophila melanogaster, GI24586591, Length=522, Percent_Identity=33.1417624521073, Blast_Score=261, Evalue=6e-70,
Organism=Drosophila melanogaster, GI24586597, Length=535, Percent_Identity=33.4579439252336, Blast_Score=259, Evalue=3e-69,
Organism=Drosophila melanogaster, GI45549022, Length=529, Percent_Identity=33.0812854442344, Blast_Score=256, Evalue=3e-68,
Organism=Drosophila melanogaster, GI24586587, Length=506, Percent_Identity=33.399209486166, Blast_Score=254, Evalue=1e-67,
Organism=Drosophila melanogaster, GI281360393, Length=479, Percent_Identity=29.4363256784969, Blast_Score=186, Evalue=3e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.10 [H]

Molecular weight: Translated: 64793; Mature: 64793

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKQWWKEAVCYQVYPRSFKDSNGDGIGDINGITEKLDYLKDLGIDVIWISPIYDSPNDD
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCC
NGYDISDYQNIMSDFGTMEDFDRLLIETHNRDMKLIMDLVVNHTSDEHPWFIESRSSVDS
CCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCCC
EYRDWYIWQDGKEGKEPNNWASIFEGSAWELDPVSNQYYFHTFSRKQPDLNWDNQKMRQS
CCCCEEEECCCCCCCCCCCHHHHHCCCCEECCCCCCCEEEEEECCCCCCCCCCHHHHHHH
IYNMINWWLDKGIDGFRVDAISHIKKSFDKGDIDNPDNLDYVPSFTRHMNQPGIQEYLEE
HHHHHHHHHHCCCCCEEHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCCHHHHHHH
VKEETFSKYDIMTVGEANGVTIEDSYEWVGEEVGKFNMVFQFEHLKLWEIHDKRLNILKY
HHHHHHCCEEEEEECCCCCEEEECCHHHHHHHCCCEEEEEEECCEEEEEECCHHHHHHHH
KNVLNDWQVGLHNKGWNALFIENHDRPRIPSTWGSENYRYESATAHGAVYFLQQGTPFIY
HHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCEEEECCCCCCEEEEEECCCCEEE
QGQEIGMTNFPFKDISEFDDVHAKNIYNVELANGRNADDIIADLQSNSRDNSRTPMQWDA
ECCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCCEEECC
SENAGFTNGTPWLKVNPNYKAINVEKELNDENSILNFYKKMIKFKKSHEIATYGDFKLIY
CCCCCCCCCCCEEEECCCEEEEEEHHHCCCCHHHHHHHHHHHHHHHCCCEEEECCEEEEE
PEDENVFAYARTLNDELLYVIGNLTSNPVKVSDSQIEFDSSDIVLNNYDIESHRRQKTLD
CCCCCEEEEEECCCCCEEEEEECCCCCCEEECCCEEEECCCCEEEECCCCHHHHHHCCCC
LKPFEVRVYHKG
CCCEEEEEEECC
>Mature Secondary Structure
MKKQWWKEAVCYQVYPRSFKDSNGDGIGDINGITEKLDYLKDLGIDVIWISPIYDSPNDD
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCC
NGYDISDYQNIMSDFGTMEDFDRLLIETHNRDMKLIMDLVVNHTSDEHPWFIESRSSVDS
CCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCCC
EYRDWYIWQDGKEGKEPNNWASIFEGSAWELDPVSNQYYFHTFSRKQPDLNWDNQKMRQS
CCCCEEEECCCCCCCCCCCHHHHHCCCCEECCCCCCCEEEEEECCCCCCCCCCHHHHHHH
IYNMINWWLDKGIDGFRVDAISHIKKSFDKGDIDNPDNLDYVPSFTRHMNQPGIQEYLEE
HHHHHHHHHHCCCCCEEHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCCHHHHHHH
VKEETFSKYDIMTVGEANGVTIEDSYEWVGEEVGKFNMVFQFEHLKLWEIHDKRLNILKY
HHHHHHCCEEEEEECCCCCEEEECCHHHHHHHCCCEEEEEEECCEEEEEECCHHHHHHHH
KNVLNDWQVGLHNKGWNALFIENHDRPRIPSTWGSENYRYESATAHGAVYFLQQGTPFIY
HHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCEEEECCCCCCEEEEEECCCCEEE
QGQEIGMTNFPFKDISEFDDVHAKNIYNVELANGRNADDIIADLQSNSRDNSRTPMQWDA
ECCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCCEEECC
SENAGFTNGTPWLKVNPNYKAINVEKELNDENSILNFYKKMIKFKKSHEIATYGDFKLIY
CCCCCCCCCCCEEEECCCEEEEEEHHHCCCCHHHHHHHHHHHHHHHCCCEEEECCEEEEE
PEDENVFAYARTLNDELLYVIGNLTSNPVKVSDSQIEFDSSDIVLNNYDIESHRRQKTLD
CCCCCEEEEEECCCCCEEEEEECCCCCCEEECCCEEEECCCCEEEECCCCHHHHHHCCCC
LKPFEVRVYHKG
CCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377 [H]