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The map label for this gene is rbsK [H]

Identifier: 222150599

GI number: 222150599

Start: 366120

End: 367019

Strand: Direct

Name: rbsK [H]

Synonym: MCCL_0349

Alternate gene names: 222150599

Gene position: 366120-367019 (Clockwise)

Preceding gene: 222150598

Following gene: 222150600

Centisome position: 17.42

GC content: 43.33

Gene sequence:

>900_bases
TTGAAAGAAAAAGTACAAGGAGTGAATAAAATGCGTGAGATTTATGTGATAGGTAGTGCTTCGATTGATTTAGTGGTTAA
GAGTGACAGACGACCGCTGAAGGGTGAGACGATATTAGGTGAATCATTCTTTATGACAACCGGCGGGAAGGGATCTAACC
AGGCGGTAAGTGCGAGTCGTCTGGGTGGTAAGGTTAAGATGGTCGGTGCTGTAGGAGCGGATGACTTCGGGCAACAAATC
TTAGCGAACTTTAGAGAGAATAGCGTTGATGTATCCAATGTGGAATCGGTTACACATGTATCGAGTGGTACAGCACATAT
TACGTTATCAGAAGATGATAACTCGATCATCGTCGTGCCGGGTGCAAACTTTGCAGTGACAACCGATCAAGTCGCACAAG
TTCTGAGTGAGGCCGCAGAAGATGCGATAGTGGTACTCCAAAATGAGATTCCTAAAGATGTCATATTGTTCACCATTGAT
CAGTGTAATGAACGCGGGTTAACGACAATTTATAATCCAGCACCATTTATAGAGATTGAACTGGATTATTTGAATAAGGT
GACTTACTTCACGCCTAATGAAACGGAAGTGAAAGAGTTGTTTGGTGAAGACTATGAAGGGGTCATCCAAGATTATCCGA
ACAAGATGATCGTAACACTAGGAGACAAAGGTGCCGTATTTTATAATGGTCAGCTTGTCAATGTGCCGGGTATTAAAGCA
GACGTGGTGGATACAACAGGCGCTGGTGATACATTTAACGGTGCACTTGCTGTGGCATTAAGTGAAGGGATGAAACTTGA
TGATGCGATATTATTTGCAAATAAGGCGGCGAGTATTTCTGTAACAGGCTTAGGTGCACAAGGCGGTATGCCCTATAGAG
CGGTGATGACAGATGTATAA

Upstream 100 bases:

>100_bases
CAGCCTTCGTATTTACTAGGAAGACTTGCGTGTGAGCAGTTGATTGATCTGCTGAATGGTAAGCAAGTGAGAAAAGAGAT
AAAGATAGATGTAAGCTTAG

Downstream 100 bases:

>100_bases
GACAGGGACGTTAAACAGTGAGATCTCTAAAGTGTTAAGTGACTTAGGACATACAGATACGATTGTCATCGGTGACTGTG
GATTGCCTGTTCCAAAGGGT

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MKEKVQGVNKMREIYVIGSASIDLVVKSDRRPLKGETILGESFFMTTGGKGSNQAVSASRLGGKVKMVGAVGADDFGQQI
LANFRENSVDVSNVESVTHVSSGTAHITLSEDDNSIIVVPGANFAVTTDQVAQVLSEAAEDAIVVLQNEIPKDVILFTID
QCNERGLTTIYNPAPFIEIELDYLNKVTYFTPNETEVKELFGEDYEGVIQDYPNKMIVTLGDKGAVFYNGQLVNVPGIKA
DVVDTTGAGDTFNGALAVALSEGMKLDDAILFANKAASISVTGLGAQGGMPYRAVMTDV

Sequences:

>Translated_299_residues
MKEKVQGVNKMREIYVIGSASIDLVVKSDRRPLKGETILGESFFMTTGGKGSNQAVSASRLGGKVKMVGAVGADDFGQQI
LANFRENSVDVSNVESVTHVSSGTAHITLSEDDNSIIVVPGANFAVTTDQVAQVLSEAAEDAIVVLQNEIPKDVILFTID
QCNERGLTTIYNPAPFIEIELDYLNKVTYFTPNETEVKELFGEDYEGVIQDYPNKMIVTLGDKGAVFYNGQLVNVPGIKA
DVVDTTGAGDTFNGALAVALSEGMKLDDAILFANKAASISVTGLGAQGGMPYRAVMTDV
>Mature_299_residues
MKEKVQGVNKMREIYVIGSASIDLVVKSDRRPLKGETILGESFFMTTGGKGSNQAVSASRLGGKVKMVGAVGADDFGQQI
LANFRENSVDVSNVESVTHVSSGTAHITLSEDDNSIIVVPGANFAVTTDQVAQVLSEAAEDAIVVLQNEIPKDVILFTID
QCNERGLTTIYNPAPFIEIELDYLNKVTYFTPNETEVKELFGEDYEGVIQDYPNKMIVTLGDKGAVFYNGQLVNVPGIKA
DVVDTTGAGDTFNGALAVALSEGMKLDDAILFANKAASISVTGLGAQGGMPYRAVMTDV

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=293, Percent_Identity=33.1058020477816, Blast_Score=143, Evalue=2e-34,
Organism=Escherichia coli, GI1790193, Length=292, Percent_Identity=33.9041095890411, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI87081971, Length=325, Percent_Identity=25.8461538461538, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI87082343, Length=296, Percent_Identity=26.3513513513513, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788491, Length=292, Percent_Identity=25.6849315068493, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17532905, Length=291, Percent_Identity=35.3951890034364, Blast_Score=132, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6319884, Length=330, Percent_Identity=32.7272727272727, Blast_Score=135, Evalue=1e-32,
Organism=Drosophila melanogaster, GI20128807, Length=302, Percent_Identity=35.7615894039735, Blast_Score=141, Evalue=5e-34,
Organism=Drosophila melanogaster, GI24583886, Length=301, Percent_Identity=26.2458471760797, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 31842; Mature: 31842

Theoretical pI: Translated: 4.23; Mature: 4.23

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEKVQGVNKMREIYVIGSASIDLVVKSDRRPLKGETILGESFFMTTGGKGSNQAVSASR
CCHHHHHHHCEEEEEEEECCEEEEEEECCCCCCCCCEEECCEEEEEECCCCCCCEEEHHH
LGGKVKMVGAVGADDFGQQILANFRENSVDVSNVESVTHVSSGTAHITLSEDDNSIIVVP
CCCEEEEEEECCCCHHHHHHHHHHHCCCCCHHHCHHHEEECCCEEEEEEECCCCEEEEEC
GANFAVTTDQVAQVLSEAAEDAIVVLQNEIPKDVILFTIDQCNERGLTTIYNPAPFIEIE
CCCEEEEHHHHHHHHHHHCCCEEEEEECCCCCEEEEEEEECCCCCCCEEEECCCCEEEEE
LDYLNKVTYFTPNETEVKELFGEDYEGVIQDYPNKMIVTLGDKGAVFYNGQLVNVPGIKA
EECCCEEEEECCCCHHHHHHHCCCCHHHHHHCCCEEEEEECCCCEEEECCEEEECCCCEE
DVVDTTGAGDTFNGALAVALSEGMKLDDAILFANKAASISVTGLGAQGGMPYRAVMTDV
EEEECCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCEEEEEEECCCCCCCEEEEECCC
>Mature Secondary Structure
MKEKVQGVNKMREIYVIGSASIDLVVKSDRRPLKGETILGESFFMTTGGKGSNQAVSASR
CCHHHHHHHCEEEEEEEECCEEEEEEECCCCCCCCCEEECCEEEEEECCCCCCCEEEHHH
LGGKVKMVGAVGADDFGQQILANFRENSVDVSNVESVTHVSSGTAHITLSEDDNSIIVVP
CCCEEEEEEECCCCHHHHHHHHHHHCCCCCHHHCHHHEEECCCEEEEEEECCCCEEEEEC
GANFAVTTDQVAQVLSEAAEDAIVVLQNEIPKDVILFTIDQCNERGLTTIYNPAPFIEIE
CCCEEEEHHHHHHHHHHHCCCEEEEEECCCCCEEEEEEEECCCCCCCEEEECCCCEEEEE
LDYLNKVTYFTPNETEVKELFGEDYEGVIQDYPNKMIVTLGDKGAVFYNGQLVNVPGIKA
EECCCEEEEECCCCHHHHHHHCCCCHHHHHHCCCEEEEEECCCCEEEECCEEEECCCCEE
DVVDTTGAGDTFNGALAVALSEGMKLDDAILFANKAASISVTGLGAQGGMPYRAVMTDV
EEEECCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCEEEEEEECCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]