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The map label for this gene is hisK [H]

Identifier: 222150594

GI number: 222150594

Start: 360959

End: 361966

Strand: Direct

Name: hisK [H]

Synonym: MCCL_0344

Alternate gene names: 222150594

Gene position: 360959-361966 (Clockwise)

Preceding gene: 222150593

Following gene: 222150597

Centisome position: 17.17

GC content: 36.41

Gene sequence:

>1008_bases
ATGAAGGTGGATTTTCATATCCATTTAGAAGAAGGACCATATACGAATAACTTCTTCAATAAAACAATAACATCGATAGA
TACAGTTAAAGGCATTCAAGCAACTCACACGCTTGATGATATCGAGCGTAAAGCACAGTTGTTCAATGAACGCATGGAAA
AAGGTGATTATTCTGAGTGGTGGCTTGATCTATACTTAGAAATGTCACTTCAAAAAGGATTGAAGCAGGTTGGTATTGTA
GACCACTTATATCGCTTCCAAGAAACGAGAAATTATTTCTTAAAGTATATGGATGTTTCTGATACGGATTTAGGGTGTAG
ACAACGAGAGTGGCTGAATCAGGTGATGACACATAAGATGGATGACTTTGTGACGTTTATCAATAGTCAGAAAGAAAAGT
GGGATAAAGCAGGTGTTGAACTGAAACTTGGCATAGAAGCGGATTACTTTATCGGCGGAGAAGAAGAACTGAAATCATTA
CTTGCACCATATGAGTTTGATTACATCATTGGTTCCGTTCATTTCAATCATGGATGGGGATTTGACAATCCAGAGTTAGA
AAATAAGTTTAATGAGTATGACTTAGTTAAACTCTATACGGATCACTTTAATACTGTGATTAAAGCAGCAGAGAGCGGGA
TATTCAGCTTTATCGCACATCTGGATAATCTGAAGGTATTTAATTATAGACCAGAAGAAGCATTGCTAATCCCGCTATAT
GAACAAGTAGCTGAAGCACTCGCGAAAAACGATGTGGCAACCGAGGTTAATGTGGGATTGAAATATCGTTATCCAGTGAA
AGAACAGTGTCCAAGCGAGCGTTTTATTAAGGTTCTTAGTGAATACGATGTAAAGTTTACGACAAGTTCTGATAGTCATT
TCCCACATGATATTGGGATATATAATGATGAAATTAGGAATTTGCTTAAGCGTAACGGAGTAAAGAGTATTGTAACGTTT
AGTAAGATGAAACGAGAAGAGAAGGATATTAAAAGCATTATTCATTAA

Upstream 100 bases:

>100_bases
GACCGTTTGAATAGAACGTATCAACAAATTAATGATAATAAGATCAAGTTATATATTAAAGAAGAAGATATGATAAAAAT
CGTTTAGGACAGGTGATAAT

Downstream 100 bases:

>100_bases
TCAATAACTGAGGAATATTAATAATTATTTATTTTATTGAAAAAATAAAACTCAGGATTTTAATAGATCCTGAGTTTTTA
ATATGAACATCATTTTCTAA

Product: histidinol-phosphatase

Products: NA

Alternate protein names: HolPase [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MKVDFHIHLEEGPYTNNFFNKTITSIDTVKGIQATHTLDDIERKAQLFNERMEKGDYSEWWLDLYLEMSLQKGLKQVGIV
DHLYRFQETRNYFLKYMDVSDTDLGCRQREWLNQVMTHKMDDFVTFINSQKEKWDKAGVELKLGIEADYFIGGEEELKSL
LAPYEFDYIIGSVHFNHGWGFDNPELENKFNEYDLVKLYTDHFNTVIKAAESGIFSFIAHLDNLKVFNYRPEEALLIPLY
EQVAEALAKNDVATEVNVGLKYRYPVKEQCPSERFIKVLSEYDVKFTTSSDSHFPHDIGIYNDEIRNLLKRNGVKSIVTF
SKMKREEKDIKSIIH

Sequences:

>Translated_335_residues
MKVDFHIHLEEGPYTNNFFNKTITSIDTVKGIQATHTLDDIERKAQLFNERMEKGDYSEWWLDLYLEMSLQKGLKQVGIV
DHLYRFQETRNYFLKYMDVSDTDLGCRQREWLNQVMTHKMDDFVTFINSQKEKWDKAGVELKLGIEADYFIGGEEELKSL
LAPYEFDYIIGSVHFNHGWGFDNPELENKFNEYDLVKLYTDHFNTVIKAAESGIFSFIAHLDNLKVFNYRPEEALLIPLY
EQVAEALAKNDVATEVNVGLKYRYPVKEQCPSERFIKVLSEYDVKFTTSSDSHFPHDIGIYNDEIRNLLKRNGVKSIVTF
SKMKREEKDIKSIIH
>Mature_335_residues
MKVDFHIHLEEGPYTNNFFNKTITSIDTVKGIQATHTLDDIERKAQLFNERMEKGDYSEWWLDLYLEMSLQKGLKQVGIV
DHLYRFQETRNYFLKYMDVSDTDLGCRQREWLNQVMTHKMDDFVTFINSQKEKWDKAGVELKLGIEADYFIGGEEELKSL
LAPYEFDYIIGSVHFNHGWGFDNPELENKFNEYDLVKLYTDHFNTVIKAAESGIFSFIAHLDNLKVFNYRPEEALLIPLY
EQVAEALAKNDVATEVNVGLKYRYPVKEQCPSERFIKVLSEYDVKFTTSSDSHFPHDIGIYNDEIRNLLKRNGVKSIVTF
SKMKREEKDIKSIIH

Specific function: Unknown

COG id: COG1387

COG function: function code ER; Histidinol phosphatase and related hydrolases of the PHP family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PHP hydrolase family. HisK subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010140
- InterPro:   IPR004013
- InterPro:   IPR016195 [H]

Pfam domain/function: PF02811 PHP [H]

EC number: =3.1.3.15 [H]

Molecular weight: Translated: 39353; Mature: 39353

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVDFHIHLEEGPYTNNFFNKTITSIDTVKGIQATHTLDDIERKAQLFNERMEKGDYSEW
CEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHH
WLDLYLEMSLQKGLKQVGIVDHLYRFQETRNYFLKYMDVSDTDLGCRQREWLNQVMTHKM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHH
DDFVTFINSQKEKWDKAGVELKLGIEADYFIGGEEELKSLLAPYEFDYIIGSVHFNHGWG
HHHHHHHHHHHHHHHHCCCEEEECCCCCEEECCHHHHHHHHCCCCEEEEEEEEEECCCCC
FDNPELENKFNEYDLVKLYTDHFNTVIKAAESGIFSFIAHLDNLKVFNYRPEEALLIPLY
CCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEHHH
EQVAEALAKNDVATEVNVGLKYRYPVKEQCPSERFIKVLSEYDVKFTTSSDSHFPHDIGI
HHHHHHHHHCCCCEEEECCEEEECCHHHHCCHHHHHHHHHHCCEEEECCCCCCCCCCCCC
YNDEIRNLLKRNGVKSIVTFSKMKREEKDIKSIIH
CHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKVDFHIHLEEGPYTNNFFNKTITSIDTVKGIQATHTLDDIERKAQLFNERMEKGDYSEW
CEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHH
WLDLYLEMSLQKGLKQVGIVDHLYRFQETRNYFLKYMDVSDTDLGCRQREWLNQVMTHKM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHH
DDFVTFINSQKEKWDKAGVELKLGIEADYFIGGEEELKSLLAPYEFDYIIGSVHFNHGWG
HHHHHHHHHHHHHHHHCCCEEEECCCCCEEECCHHHHHHHHCCCCEEEEEEEEEECCCCC
FDNPELENKFNEYDLVKLYTDHFNTVIKAAESGIFSFIAHLDNLKVFNYRPEEALLIPLY
CCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEHHH
EQVAEALAKNDVATEVNVGLKYRYPVKEQCPSERFIKVLSEYDVKFTTSSDSHFPHDIGI
HHHHHHHHHCCCCEEEECCEEEECCHHHHCCHHHHHHHHHHCCEEEECCCCCCCCCCCCC
YNDEIRNLLKRNGVKSIVTFSKMKREEKDIKSIIH
CHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]