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The map label for this gene is 222150560

Identifier: 222150560

GI number: 222150560

Start: 316717

End: 317895

Strand: Direct

Name: 222150560

Synonym: MCCL_0310

Alternate gene names: NA

Gene position: 316717-317895 (Clockwise)

Preceding gene: 222150559

Following gene: 222150561

Centisome position: 15.07

GC content: 38.42

Gene sequence:

>1179_bases
ATGGAAAAGCACTTAAAAAAATATCACCATCATCAACTATTAAACCATATGGAGTTATTGTCTCAAGTTGAAAAACAAAG
ACTAGAAGAAACGTTATCCATTCAAGATTTTGAAAAGATAGATCAGTTGTATCAAGATGTCTATGTTCATCGACAGATTG
CGCTTCCGGAAGATGTTCAAGATATCGCAACAACCATTATTAGTGAGCAATCAACAGAAGCGCTGGCACATATGGAGGCA
TTAGGGCAAAGTGCTATTAAAGCTGGCAAGTTTGCCGCAGTTCTAATGGCTGGTGGACAAGGTACACGTCTCGCGCATAA
TGGGCCGAAAGGTACATTTGAATTTGATGGTGTGAGTCTGTTTGAACTTCAGGCAAGACAAATAAAAGCATTGATTGAAA
GCTTGAACGTGTCAATACCTTGGGTCATTATGACAAGTGATATTAACCATAAAGAAACAATCGCTTTCTTTGAAGCGCAT
GATTATTTCGGATTAGATAAACAGGATGTCTTTTTCTTCATTCAACCTAATATTGTAGCATTGAGTGAAGGTGGAGAGCT
ATTACTCAATGAGGACAAACAGCTGCTGACAACACCGAACGGTAACGGTGGAATCTTTGAAGCATTGAATGCATCAGGTA
CGAATAAGCTGTTACAAGAAAGAGGCGTTACACACATTTACATGAATAATATCGATAATGTACTCGTAAAAGTGCTGGAC
CCGGTACTTTGTGGCTATGCAGTTGAAAGTGACGCAGATGTTACAACGAAGACGATTGCAGCAAAAGATAATGAAAGTGT
CGGCCGCGTTGTGGAAGTGAATGGGAAAAAACAAGTCATTGAATACACTGAGCTTCCTAAAGGAGAAGAGAATCATTTCC
GTAATGCGAATATCGGAATTCATATATTTAAGCTTGATTTCATTGTGAATCATGCACAAAGTGAAATGCCTTATCACCTG
GCGATTAAACAGCTGCCGCAGTTAGATGAGAGTTTTACTGTTATTGAAGCTACAGCATTAAAGTTTGAGAAGTTCTACTT
TGATATATTCAAATATGCGGATACTTTTAAGACGGTACAGTTTGATCGTAATGAAGAGTTCAGTCCTTTGAAGAATAAAG
AAGGAAAAGATAGCATCGCAACAGCTTACGAAGATTTGTTGCGCACACATCGACTATAA

Upstream 100 bases:

>100_bases
TTCGCTTGCAACGGCATTCAGTCTTGTAACAATGTATATTGTCTATAATGAGATTATCCACAGAACGATAAGTTGGATAA
AATATTAAAGGAGTTTTATT

Downstream 100 bases:

>100_bases
GAGGTGACCGATTTGAAAAATAAAACAACAATCTATGTGATGTTCATGATGCTTTTGATTGCAGCGATAAATCTTGGACT
TAGTTATCATTATATATTTA

Product: hypothetical protein

Products: diphosphate; UDP-N-acetyl-D-glucosamine

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MEKHLKKYHHHQLLNHMELLSQVEKQRLEETLSIQDFEKIDQLYQDVYVHRQIALPEDVQDIATTIISEQSTEALAHMEA
LGQSAIKAGKFAAVLMAGGQGTRLAHNGPKGTFEFDGVSLFELQARQIKALIESLNVSIPWVIMTSDINHKETIAFFEAH
DYFGLDKQDVFFFIQPNIVALSEGGELLLNEDKQLLTTPNGNGGIFEALNASGTNKLLQERGVTHIYMNNIDNVLVKVLD
PVLCGYAVESDADVTTKTIAAKDNESVGRVVEVNGKKQVIEYTELPKGEENHFRNANIGIHIFKLDFIVNHAQSEMPYHL
AIKQLPQLDESFTVIEATALKFEKFYFDIFKYADTFKTVQFDRNEEFSPLKNKEGKDSIATAYEDLLRTHRL

Sequences:

>Translated_392_residues
MEKHLKKYHHHQLLNHMELLSQVEKQRLEETLSIQDFEKIDQLYQDVYVHRQIALPEDVQDIATTIISEQSTEALAHMEA
LGQSAIKAGKFAAVLMAGGQGTRLAHNGPKGTFEFDGVSLFELQARQIKALIESLNVSIPWVIMTSDINHKETIAFFEAH
DYFGLDKQDVFFFIQPNIVALSEGGELLLNEDKQLLTTPNGNGGIFEALNASGTNKLLQERGVTHIYMNNIDNVLVKVLD
PVLCGYAVESDADVTTKTIAAKDNESVGRVVEVNGKKQVIEYTELPKGEENHFRNANIGIHIFKLDFIVNHAQSEMPYHL
AIKQLPQLDESFTVIEATALKFEKFYFDIFKYADTFKTVQFDRNEEFSPLKNKEGKDSIATAYEDLLRTHRL
>Mature_392_residues
MEKHLKKYHHHQLLNHMELLSQVEKQRLEETLSIQDFEKIDQLYQDVYVHRQIALPEDVQDIATTIISEQSTEALAHMEA
LGQSAIKAGKFAAVLMAGGQGTRLAHNGPKGTFEFDGVSLFELQARQIKALIESLNVSIPWVIMTSDINHKETIAFFEAH
DYFGLDKQDVFFFIQPNIVALSEGGELLLNEDKQLLTTPNGNGGIFEALNASGTNKLLQERGVTHIYMNNIDNVLVKVLD
PVLCGYAVESDADVTTKTIAAKDNESVGRVVEVNGKKQVIEYTELPKGEENHFRNANIGIHIFKLDFIVNHAQSEMPYHL
AIKQLPQLDESFTVIEATALKFEKFYFDIFKYADTFKTVQFDRNEEFSPLKNKEGKDSIATAYEDLLRTHRL

Specific function: Unknown

COG id: COG4284

COG function: function code G; UDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDPGP type 1 family [H]

Homologues:

Organism=Homo sapiens, GI156627575, Length=425, Percent_Identity=32.4705882352941, Blast_Score=201, Evalue=9e-52,
Organism=Homo sapiens, GI187936958, Length=351, Percent_Identity=33.6182336182336, Blast_Score=187, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17552518, Length=418, Percent_Identity=32.5358851674641, Blast_Score=192, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI193206427, Length=337, Percent_Identity=32.9376854599407, Blast_Score=166, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6320100, Length=401, Percent_Identity=33.1670822942643, Blast_Score=202, Evalue=1e-52,
Organism=Drosophila melanogaster, GI19920822, Length=352, Percent_Identity=35.7954545454545, Blast_Score=202, Evalue=3e-52,
Organism=Drosophila melanogaster, GI24582229, Length=352, Percent_Identity=36.0795454545455, Blast_Score=202, Evalue=3e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002618 [H]

Pfam domain/function: PF01704 UDPGP [H]

EC number: 2.7.7.23

Molecular weight: Translated: 44369; Mature: 44369

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKHLKKYHHHQLLNHMELLSQVEKQRLEETLSIQDFEKIDQLYQDVYVHRQIALPEDVQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCHHH
DIATTIISEQSTEALAHMEALGQSAIKAGKFAAVLMAGGQGTRLAHNGPKGTFEFDGVSL
HHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEECCCCCCCEEECCEEH
FELQARQIKALIESLNVSIPWVIMTSDINHKETIAFFEAHDYFGLDKQDVFFFIQPNIVA
HHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCEEEEECCCEEE
LSEGGELLLNEDKQLLTTPNGNGGIFEALNASGTNKLLQERGVTHIYMNNIDNVLVKVLD
ECCCCCEEECCCCEEEECCCCCCCEEEECCCCCHHHHHHHCCCEEEEECCHHHHHHHHHH
PVLCGYAVESDADVTTKTIAAKDNESVGRVVEVNGKKQVIEYTELPKGEENHFRNANIGI
HHHHCCEECCCCCCCEEEEECCCCCCCCCEEEECCCCEEEEHHCCCCCCCCCCCCCCCEE
HIFKLDFIVNHAQSEMPYHLAIKQLPQLDESFTVIEATALKFEKFYFDIFKYADTFKTVQ
EEEEEEEHHHHHHHCCCHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHEEE
FDRNEEFSPLKNKEGKDSIATAYEDLLRTHRL
ECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEKHLKKYHHHQLLNHMELLSQVEKQRLEETLSIQDFEKIDQLYQDVYVHRQIALPEDVQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCHHH
DIATTIISEQSTEALAHMEALGQSAIKAGKFAAVLMAGGQGTRLAHNGPKGTFEFDGVSL
HHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEECCCCCCCEEECCEEH
FELQARQIKALIESLNVSIPWVIMTSDINHKETIAFFEAHDYFGLDKQDVFFFIQPNIVA
HHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCEEEEECCCEEE
LSEGGELLLNEDKQLLTTPNGNGGIFEALNASGTNKLLQERGVTHIYMNNIDNVLVKVLD
ECCCCCEEECCCCEEEECCCCCCCEEEECCCCCHHHHHHHCCCEEEEECCHHHHHHHHHH
PVLCGYAVESDADVTTKTIAAKDNESVGRVVEVNGKKQVIEYTELPKGEENHFRNANIGI
HHHHCCEECCCCCCCEEEEECCCCCCCCCEEEECCCCEEEEHHCCCCCCCCCCCCCCCEE
HIFKLDFIVNHAQSEMPYHLAIKQLPQLDESFTVIEATALKFEKFYFDIFKYADTFKTVQ
EEEEEEEHHHHHHHCCCHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHEEE
FDRNEEFSPLKNKEGKDSIATAYEDLLRTHRL
ECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UTP; N-acetyl-alpha-D-glucosamine 1-phosphate

Specific reaction: UTP + N-acetyl-alpha-D-glucosamine 1-phosphate = diphosphate + UDP-N-acetyl-D-glucosamine

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA