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The map label for this gene is steT [H]

Identifier: 222150538

GI number: 222150538

Start: 294643

End: 295959

Strand: Direct

Name: steT [H]

Synonym: MCCL_0288

Alternate gene names: 222150538

Gene position: 294643-295959 (Clockwise)

Preceding gene: 222150537

Following gene: 222150539

Centisome position: 14.02

GC content: 38.8

Gene sequence:

>1317_bases
ATGGAAAATAAAAATATAATTCAAAAAAATATTGGATTCTTTCCGGCACTTGCACTCGTTATGGGAACTGTTATCGGTTC
AGGTGTTTTCTTTAAAGTATCCAATATAACAGAAGTCACAGGAACACCAGGAATGACTTTGCTTGTATGGCTGCTAGGAG
GAGTGATTACAATCTGTGCTGGTCTTACAGTCGCTGAGCTTGCAGCTGCAATTCCGAGGAATGGCGGATTGACAACATAT
ATAGAATATACATATGGCAAATTTTCAGGGTTTTTGGCAGGATGGGCACAAAGTTTTATCTACTTTCCAGCGATGATTGC
TGCACAGGCAATTGTATTTTCAGAACAAGTACTCAACTTATTACATCTTAAAGACGGGTGGATTGTGCCAGTTGCATTTA
TTGCAGTGGCTTCGATTTACCTGATTAATATTATCGGATCTAAGACAGGTGGTATACTACAGTCTGTAACGCTAGTGGTT
AAACTTATTCCATTAATCGTTATCATTATATTCGGTCTGATGAATACTGGAGACGTTGAAGTATCGCTTGCACCGAACAC
CGGAGATACCGGTATTAATTTCTTTACAGCGATTGGTGCAGGATTACTTGCAACGATGTTTGCGTATGATGGCTGGATTC
ATGTCGGCAATATTGCCGGGGAAATGAAGAATCCAAAGCGTGACTTGCCACTTGCAATTGTTCTAGGATTAGGATTAGTG
ACAGTCATCTATCTTCTGATAAATGCTACGTTTTTATATACGATGCCTATCGAAGATTTAAAAGGAAATTTAAGTGCAGC
TACAGATGCATCTGAAATGTTATTAGGAGATATGGGTGGGAAACTCGTTACAATCGGTATATTAATTTCAGTTTACGGTG
CATTAAATGGTTATACAATGACAGGAATGCGTCTGCCTTATGCTATGGCAGAGAAGAACATCCTGCCATTTAAAGAATCA
TTTATGAAAGTGACAAATGCAGGTATACCATGGTTCAGTGGGCTTGTTCAAGTGATTATCGGAGCGATCATGATTACTTC
ACGCTCGTTTGATGCAATAACGAATATGCTTGTATTCGTTATCTGGGCATTCTATGTGATGGCATTCTATGCGGTGTTTG
TACTAAGAAAGCGTGAAAGTGAGCTGGAACGACCTTACAAAGTACCGTTATATCCGGTGATACCAGCCATTGCAATTATT
GCAGGTGTGTTCGTAATGGTAAATACATTATTCACACAACCAGTGTTAGCGATTGTTGGGATTATTATAACGTTACTTGG
AATACCGATTTATAAGATGAGGATTAGAGTAAAATAA

Upstream 100 bases:

>100_bases
ATGAACCGCTATTGTTAAGCGCAGCAAATTTATTGCTGCGCTTTTAACAATTTAAAGCAAGAATATGCTATCATGATAAA
TGCTCAAAAAGGAGGATGTT

Downstream 100 bases:

>100_bases
TAAAATATATCAGTCTATCAGTAGGCTGATATATTTTTTTAGTATGGATTATCAGCTCTTCTTTTGTGCTATATTATCAT
TAAAGGGGGATAGAGATGAC

Product: amino acid permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MENKNIIQKNIGFFPALALVMGTVIGSGVFFKVSNITEVTGTPGMTLLVWLLGGVITICAGLTVAELAAAIPRNGGLTTY
IEYTYGKFSGFLAGWAQSFIYFPAMIAAQAIVFSEQVLNLLHLKDGWIVPVAFIAVASIYLINIIGSKTGGILQSVTLVV
KLIPLIVIIIFGLMNTGDVEVSLAPNTGDTGINFFTAIGAGLLATMFAYDGWIHVGNIAGEMKNPKRDLPLAIVLGLGLV
TVIYLLINATFLYTMPIEDLKGNLSAATDASEMLLGDMGGKLVTIGILISVYGALNGYTMTGMRLPYAMAEKNILPFKES
FMKVTNAGIPWFSGLVQVIIGAIMITSRSFDAITNMLVFVIWAFYVMAFYAVFVLRKRESELERPYKVPLYPVIPAIAII
AGVFVMVNTLFTQPVLAIVGIIITLLGIPIYKMRIRVK

Sequences:

>Translated_438_residues
MENKNIIQKNIGFFPALALVMGTVIGSGVFFKVSNITEVTGTPGMTLLVWLLGGVITICAGLTVAELAAAIPRNGGLTTY
IEYTYGKFSGFLAGWAQSFIYFPAMIAAQAIVFSEQVLNLLHLKDGWIVPVAFIAVASIYLINIIGSKTGGILQSVTLVV
KLIPLIVIIIFGLMNTGDVEVSLAPNTGDTGINFFTAIGAGLLATMFAYDGWIHVGNIAGEMKNPKRDLPLAIVLGLGLV
TVIYLLINATFLYTMPIEDLKGNLSAATDASEMLLGDMGGKLVTIGILISVYGALNGYTMTGMRLPYAMAEKNILPFKES
FMKVTNAGIPWFSGLVQVIIGAIMITSRSFDAITNMLVFVIWAFYVMAFYAVFVLRKRESELERPYKVPLYPVIPAIAII
AGVFVMVNTLFTQPVLAIVGIIITLLGIPIYKMRIRVK
>Mature_438_residues
MENKNIIQKNIGFFPALALVMGTVIGSGVFFKVSNITEVTGTPGMTLLVWLLGGVITICAGLTVAELAAAIPRNGGLTTY
IEYTYGKFSGFLAGWAQSFIYFPAMIAAQAIVFSEQVLNLLHLKDGWIVPVAFIAVASIYLINIIGSKTGGILQSVTLVV
KLIPLIVIIIFGLMNTGDVEVSLAPNTGDTGINFFTAIGAGLLATMFAYDGWIHVGNIAGEMKNPKRDLPLAIVLGLGLV
TVIYLLINATFLYTMPIEDLKGNLSAATDASEMLLGDMGGKLVTIGILISVYGALNGYTMTGMRLPYAMAEKNILPFKES
FMKVTNAGIPWFSGLVQVIIGAIMITSRSFDAITNMLVFVIWAFYVMAFYAVFVLRKRESELERPYKVPLYPVIPAIAII
AGVFVMVNTLFTQPVLAIVGIIITLLGIPIYKMRIRVK

Specific function: Exhibits an obligate exchange activity for serine, threonine and aromatic amino acids [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family [H]

Homologues:

Organism=Homo sapiens, GI187423910, Length=421, Percent_Identity=30.4038004750594, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI7657591, Length=421, Percent_Identity=30.4038004750594, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI33286428, Length=444, Percent_Identity=27.9279279279279, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI71979932, Length=437, Percent_Identity=29.5194508009153, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI7657683, Length=407, Percent_Identity=28.009828009828, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI115648063, Length=437, Percent_Identity=26.7734553775744, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI115648022, Length=437, Percent_Identity=26.7734553775744, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI186910308, Length=437, Percent_Identity=25.4004576659039, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI186910306, Length=437, Percent_Identity=25.4004576659039, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI186910304, Length=437, Percent_Identity=25.4004576659039, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI9790235, Length=442, Percent_Identity=29.4117647058824, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI33286430, Length=234, Percent_Identity=28.2051282051282, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI71999149, Length=417, Percent_Identity=24.220623501199, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI87082250, Length=440, Percent_Identity=27.7272727272727, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI2367353, Length=348, Percent_Identity=27.8735632183908, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI87081708, Length=421, Percent_Identity=24.4655581947743, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786694, Length=428, Percent_Identity=22.6635514018692, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788480, Length=446, Percent_Identity=23.7668161434978, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1786908, Length=357, Percent_Identity=24.6498599439776, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17540018, Length=441, Percent_Identity=25.8503401360544, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17568033, Length=438, Percent_Identity=26.9406392694064, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI71982608, Length=447, Percent_Identity=27.0693512304251, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI71982612, Length=447, Percent_Identity=27.0693512304251, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI71990446, Length=461, Percent_Identity=24.5119305856833, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI32566699, Length=282, Percent_Identity=26.9503546099291, Blast_Score=112, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI71995382, Length=464, Percent_Identity=25.2155172413793, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI71995388, Length=464, Percent_Identity=25, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI71993915, Length=450, Percent_Identity=24.8888888888889, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI193208714, Length=410, Percent_Identity=24.390243902439, Blast_Score=98, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI32566695, Length=410, Percent_Identity=24.390243902439, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71982623, Length=275, Percent_Identity=26.9090909090909, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17532491, Length=335, Percent_Identity=22.6865671641791, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6321492, Length=327, Percent_Identity=25.0764525993884, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6321751, Length=432, Percent_Identity=21.2962962962963, Blast_Score=70, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24651635, Length=431, Percent_Identity=27.1461716937355, Blast_Score=152, Evalue=3e-37,
Organism=Drosophila melanogaster, GI24651633, Length=431, Percent_Identity=27.1461716937355, Blast_Score=152, Evalue=3e-37,
Organism=Drosophila melanogaster, GI21357367, Length=450, Percent_Identity=27.5555555555556, Blast_Score=152, Evalue=5e-37,
Organism=Drosophila melanogaster, GI45550968, Length=446, Percent_Identity=28.0269058295964, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI19921172, Length=446, Percent_Identity=28.0269058295964, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI221331183, Length=434, Percent_Identity=26.7281105990783, Blast_Score=148, Evalue=6e-36,
Organism=Drosophila melanogaster, GI17647653, Length=434, Percent_Identity=26.7281105990783, Blast_Score=148, Evalue=6e-36,
Organism=Drosophila melanogaster, GI24664379, Length=434, Percent_Identity=26.7281105990783, Blast_Score=148, Evalue=6e-36,
Organism=Drosophila melanogaster, GI24641993, Length=393, Percent_Identity=27.9898218829517, Blast_Score=145, Evalue=6e-35,
Organism=Drosophila melanogaster, GI24641995, Length=393, Percent_Identity=27.9898218829517, Blast_Score=145, Evalue=8e-35,
Organism=Drosophila melanogaster, GI24668806, Length=408, Percent_Identity=23.0392156862745, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21356285, Length=408, Percent_Identity=23.0392156862745, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24668802, Length=408, Percent_Identity=23.0392156862745, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24667468, Length=336, Percent_Identity=23.5119047619048, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 47292; Mature: 47292

Theoretical pI: Translated: 9.22; Mature: 9.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENKNIIQKNIGFFPALALVMGTVIGSGVFFKVSNITEVTGTPGMTLLVWLLGGVITICA
CCCCHHHHHHCCHHHHHHHHHHHHHCCCEEEEECCEEECCCCCHHHHHHHHHHHHHHHHH
GLTVAELAAAIPRNGGLTTYIEYTYGKFSGFLAGWAQSFIYFPAMIAAQAIVFSEQVLNL
CHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHLKDGWIVPVAFIAVASIYLINIIGSKTGGILQSVTLVVKLIPLIVIIIFGLMNTGDVE
HHCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
VSLAPNTGDTGINFFTAIGAGLLATMFAYDGWIHVGNIAGEMKNPKRDLPLAIVLGLGLV
EEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEECCHHHCCCCCCCCCCHHHHHHHHHH
TVIYLLINATFLYTMPIEDLKGNLSAATDASEMLLGDMGGKLVTIGILISVYGALNGYTM
HHHHHHHHHHHHEEECHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEE
TGMRLPYAMAEKNILPFKESFMKVTNAGIPWFSGLVQVIIGAIMITSRSFDAITNMLVFV
ECCCCCHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
IWAFYVMAFYAVFVLRKRESELERPYKVPLYPVIPAIAIIAGVFVMVNTLFTQPVLAIVG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IIITLLGIPIYKMRIRVK
HHHHHHCCCEEEEEEEEC
>Mature Secondary Structure
MENKNIIQKNIGFFPALALVMGTVIGSGVFFKVSNITEVTGTPGMTLLVWLLGGVITICA
CCCCHHHHHHCCHHHHHHHHHHHHHCCCEEEEECCEEECCCCCHHHHHHHHHHHHHHHHH
GLTVAELAAAIPRNGGLTTYIEYTYGKFSGFLAGWAQSFIYFPAMIAAQAIVFSEQVLNL
CHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHLKDGWIVPVAFIAVASIYLINIIGSKTGGILQSVTLVVKLIPLIVIIIFGLMNTGDVE
HHCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
VSLAPNTGDTGINFFTAIGAGLLATMFAYDGWIHVGNIAGEMKNPKRDLPLAIVLGLGLV
EEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEECCHHHCCCCCCCCCCHHHHHHHHHH
TVIYLLINATFLYTMPIEDLKGNLSAATDASEMLLGDMGGKLVTIGILISVYGALNGYTM
HHHHHHHHHHHHEEECHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEE
TGMRLPYAMAEKNILPFKESFMKVTNAGIPWFSGLVQVIIGAIMITSRSFDAITNMLVFV
ECCCCCHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
IWAFYVMAFYAVFVLRKRESELERPYKVPLYPVIPAIAIIAGVFVMVNTLFTQPVLAIVG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IIITLLGIPIYKMRIRVK
HHHHHHCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]