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The map label for this gene is hsdM [H]

Identifier: 222150484

GI number: 222150484

Start: 227997

End: 229874

Strand: Direct

Name: hsdM [H]

Synonym: MCCL_0234

Alternate gene names: 222150484

Gene position: 227997-229874 (Clockwise)

Preceding gene: 222150483

Following gene: 222150485

Centisome position: 10.84

GC content: 31.58

Gene sequence:

>1878_bases
ATGATTGGTAATAAATTGCAAGAAAATAAAAATATGAAGCCAAATAGTCTTGAAATGGAAAAACTTAAAGAGGTACTACC
TCAATATTTTAACAATAAAGGTGAATTTGAAATAGACAAATTTAAAGATTTTCTAAAATTAGAAGAGGTTGACCTTTCAA
AAGAAGGATATGGATTAGAATTTTTAGGACAATCTTATGCTAAATATCTTAGTTCACTGGAAACAGAAACTTATCTTTCA
CCTGATATTGAACATAATTCTAAAGAAGAAAACCGTAATAGTGAAAATTTGTATATCGTTGGGGATAATATTGATGCTTT
AAAGCATTTGCTGAACTCTTATGCAGGAAGAATTAAATGTATTTACATCGATCCACCTTATAATACAGGTTCGGATGGCT
TTGTTTATCCTGATAACTTTCAGTTTAATTCGGAAGAACTATCTAATAGAATTGGAATTACAGAAGAAGAGGCCAAAAGA
ATACTTGATTTAGCTGGGAAGAGTACGCACTCTGCATGGCTTACGTTTATGTATCCAAGGTTATTATTGGCTAGAGACTT
ATTGTCTAAGAATGGTGTTATTTTTATTTCAATTGATGATAATGAGCAAGGGAATCTACGATTAATTTGTGATGAAATAT
TTGGTGAAGAAAATTTTGAAGGACACGTTCACTGGAGAAGAAGAAGTAATCAACCTAATGATAGATCAAAAATGATTGGA
TTAGTAGCGGAACATATACTTATTTATGCAAAAAATAGCTTATTTCTAAAAGAATATGGAGTTGGAAAAATTGGATTAAC
GGGTAATTTTTCTAATCCAGATAATGATCCTCGTGGTTTATGGAATAGTAAGCCATGGAAAGTAGGCTCGGATCAATCAG
GAAGTAGATACAAAATAACAACTCCTGACGGAAGAGTTTTAGATGAGGAATGGATGGGAGATGAACAAAGTTATCTTAAA
TTGATAGAGGATAATAGAATTTATTTTCCTAAAGAAGGAAGAGGGTGGCCAAGAAAAAAGATTTTTAAAGAGGAGAGAGA
ATTAGAAGGACAATGTGCTAATAATTGGTGGAATCATACAGAGTTTGGTTCTAATCAAAAAGGTTCAGCCAGATTAACTG
ATTTATTTGAAGGGAATCAGAATCTTTTTTCAAAACCCAAACCTACAGAGTTAATTGAAGGGATTTTGAACGTTACTACA
ACCGATGATGATTTTTATATCCTAGACTTCTTTTCAGGTTCAGCCACTACTGCGGATGCTGTAATGCAATTAAATGCGGA
GGATCAAGGGAAAAGAAAATATTTAATGGTTCAACTGCCAGAAAGTATTGAAAAGAATAAGCCTGCATATAAACTGGGTT
ATAAAACTCTAGATGAAGTAGGTAGAGCTAGAATAGAAAAAGCTGCTAATAAGATAAAAATAGAAACTAATGCTGACATA
GATTATGGATATAAACTCTACTACTTGGAAACGCCTGAAGAAAAAACCTTGATTGAATTAGAAAATTTTGAACCAGAACT
CAAATTGATTACGGATGATATGATATCTGTATTTGATAATAATCATTCTTCAGGGAAAGAAAGCATATTAGCTACTTGGA
TCAATGAAGATGGCTACGGTTTAACGAAATGTTCAACCCCCTATAAACTTGAACATTATTCAGCAGATTTTATTGATAAA
TCTCTTTATATTATCGATGAAGGTCTAGAAGATGAAGATGTAATGACTTTAATCAAACGTATTGAGAATGAAGAATTAGA
AATTAATAGAGTTGTTGTGTACGTTCATTCTATTCGCTTTAATGTTCTTCAAGAGTTGAGAAAAAATCTCAAAGTTTTAA
GAAATAACAAAAATGTGACATTGATTGAGAGGTTTTAG

Upstream 100 bases:

>100_bases
TGAGTTTGTGGCAATGGAAGTTCTGTATAGGATTGGAAAAGAATTAGAAGCCGATTTTGGTGATATGGTATCTTTGAAGA
TAAACCAGGAGGAGAAGTAA

Downstream 100 bases:

>100_bases
TTATGAGTATTGAATTATCCATTTTGCCTCATCAAAATGAGTTTCTGAAAGCTGTTCGAAAAGCCTTTGAAGATATTCGT
GTTATGTCTAATGAAGATAT

Product: type III restriction-modification system methyltransferase subunit

Products: NA

Alternate protein names: M.StyLTI; StyLTI methyltransferase [H]

Number of amino acids: Translated: 625; Mature: 625

Protein sequence:

>625_residues
MIGNKLQENKNMKPNSLEMEKLKEVLPQYFNNKGEFEIDKFKDFLKLEEVDLSKEGYGLEFLGQSYAKYLSSLETETYLS
PDIEHNSKEENRNSENLYIVGDNIDALKHLLNSYAGRIKCIYIDPPYNTGSDGFVYPDNFQFNSEELSNRIGITEEEAKR
ILDLAGKSTHSAWLTFMYPRLLLARDLLSKNGVIFISIDDNEQGNLRLICDEIFGEENFEGHVHWRRRSNQPNDRSKMIG
LVAEHILIYAKNSLFLKEYGVGKIGLTGNFSNPDNDPRGLWNSKPWKVGSDQSGSRYKITTPDGRVLDEEWMGDEQSYLK
LIEDNRIYFPKEGRGWPRKKIFKEERELEGQCANNWWNHTEFGSNQKGSARLTDLFEGNQNLFSKPKPTELIEGILNVTT
TDDDFYILDFFSGSATTADAVMQLNAEDQGKRKYLMVQLPESIEKNKPAYKLGYKTLDEVGRARIEKAANKIKIETNADI
DYGYKLYYLETPEEKTLIELENFEPELKLITDDMISVFDNNHSSGKESILATWINEDGYGLTKCSTPYKLEHYSADFIDK
SLYIIDEGLEDEDVMTLIKRIENEELEINRVVVYVHSIRFNVLQELRKNLKVLRNNKNVTLIERF

Sequences:

>Translated_625_residues
MIGNKLQENKNMKPNSLEMEKLKEVLPQYFNNKGEFEIDKFKDFLKLEEVDLSKEGYGLEFLGQSYAKYLSSLETETYLS
PDIEHNSKEENRNSENLYIVGDNIDALKHLLNSYAGRIKCIYIDPPYNTGSDGFVYPDNFQFNSEELSNRIGITEEEAKR
ILDLAGKSTHSAWLTFMYPRLLLARDLLSKNGVIFISIDDNEQGNLRLICDEIFGEENFEGHVHWRRRSNQPNDRSKMIG
LVAEHILIYAKNSLFLKEYGVGKIGLTGNFSNPDNDPRGLWNSKPWKVGSDQSGSRYKITTPDGRVLDEEWMGDEQSYLK
LIEDNRIYFPKEGRGWPRKKIFKEERELEGQCANNWWNHTEFGSNQKGSARLTDLFEGNQNLFSKPKPTELIEGILNVTT
TDDDFYILDFFSGSATTADAVMQLNAEDQGKRKYLMVQLPESIEKNKPAYKLGYKTLDEVGRARIEKAANKIKIETNADI
DYGYKLYYLETPEEKTLIELENFEPELKLITDDMISVFDNNHSSGKESILATWINEDGYGLTKCSTPYKLEHYSADFIDK
SLYIIDEGLEDEDVMTLIKRIENEELEINRVVVYVHSIRFNVLQELRKNLKVLRNNKNVTLIERF
>Mature_625_residues
MIGNKLQENKNMKPNSLEMEKLKEVLPQYFNNKGEFEIDKFKDFLKLEEVDLSKEGYGLEFLGQSYAKYLSSLETETYLS
PDIEHNSKEENRNSENLYIVGDNIDALKHLLNSYAGRIKCIYIDPPYNTGSDGFVYPDNFQFNSEELSNRIGITEEEAKR
ILDLAGKSTHSAWLTFMYPRLLLARDLLSKNGVIFISIDDNEQGNLRLICDEIFGEENFEGHVHWRRRSNQPNDRSKMIG
LVAEHILIYAKNSLFLKEYGVGKIGLTGNFSNPDNDPRGLWNSKPWKVGSDQSGSRYKITTPDGRVLDEEWMGDEQSYLK
LIEDNRIYFPKEGRGWPRKKIFKEERELEGQCANNWWNHTEFGSNQKGSARLTDLFEGNQNLFSKPKPTELIEGILNVTT
TDDDFYILDFFSGSATTADAVMQLNAEDQGKRKYLMVQLPESIEKNKPAYKLGYKTLDEVGRARIEKAANKIKIETNADI
DYGYKLYYLETPEEKTLIELENFEPELKLITDDMISVFDNNHSSGKESILATWINEDGYGLTKCSTPYKLEHYSADFIDK
SLYIIDEGLEDEDVMTLIKRIENEELEINRVVVYVHSIRFNVLQELRKNLKVLRNNKNVTLIERF

Specific function: Binds the system-specific DNA recognition site 5'-CAGAG- 3'. Necessary for restriction and for methylation of A-4 [H]

COG id: COG2189

COG function: function code L; Adenine specific DNA methylase Mod

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002295
- InterPro:   IPR002941
- InterPro:   IPR002052 [H]

Pfam domain/function: PF01555 N6_N4_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 72311; Mature: 72311

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGNKLQENKNMKPNSLEMEKLKEVLPQYFNNKGEFEIDKFKDFLKLEEVDLSKEGYGLE
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCCCCCCCHH
FLGQSYAKYLSSLETETYLSPDIEHNSKEENRNSENLYIVGDNIDALKHLLNSYAGRIKC
HHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHCCCEEEE
IYIDPPYNTGSDGFVYPDNFQFNSEELSNRIGITEEEAKRILDLAGKSTHSAWLTFMYPR
EEECCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHH
LLLARDLLSKNGVIFISIDDNEQGNLRLICDEIFGEENFEGHVHWRRRSNQPNDRSKMIG
HHHHHHHHCCCCEEEEEECCCCCCCEEEEEHHHCCCCCCCCEEEEEECCCCCCHHHHHHH
LVAEHILIYAKNSLFLKEYGVGKIGLTGNFSNPDNDPRGLWNSKPWKVGSDQSGSRYKIT
HHHHHHEEEECCCEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEE
TPDGRVLDEEWMGDEQSYLKLIEDNRIYFPKEGRGWPRKKIFKEERELEGQCANNWWNHT
CCCCCEECHHHCCCHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHCCCCHHCCCCCCC
EFGSNQKGSARLTDLFEGNQNLFSKPKPTELIEGILNVTTTDDDFYILDFFSGSATTADA
CCCCCCCCCCHHHHHHCCCHHHCCCCCHHHHHHHHHCCEECCCCEEEEEEECCCCCCCHH
VMQLNAEDQGKRKYLMVQLPESIEKNKPAYKLGYKTLDEVGRARIEKAANKIKIETNADI
EEEECCCCCCCEEEEEEECCHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHEEEEEECCCC
DYGYKLYYLETPEEKTLIELENFEPELKLITDDMISVFDNNHSSGKESILATWINEDGYG
CCCEEEEEEECCCCCCEEEEECCCCCEEEHHHHHHHHHCCCCCCCCCEEEEEEECCCCCE
LTKCSTPYKLEHYSADFIDKSLYIIDEGLEDEDVMTLIKRIENEELEINRVVVYVHSIRF
EEECCCCCEECCCCHHHHCCEEEEEECCCCHHHHHHHHHHHCCCCEEEEEEEEEEEHHHH
NVLQELRKNLKVLRNNKNVTLIERF
HHHHHHHHHHHHHCCCCCEEEEEEC
>Mature Secondary Structure
MIGNKLQENKNMKPNSLEMEKLKEVLPQYFNNKGEFEIDKFKDFLKLEEVDLSKEGYGLE
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCCCCCCCHH
FLGQSYAKYLSSLETETYLSPDIEHNSKEENRNSENLYIVGDNIDALKHLLNSYAGRIKC
HHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHCCCEEEE
IYIDPPYNTGSDGFVYPDNFQFNSEELSNRIGITEEEAKRILDLAGKSTHSAWLTFMYPR
EEECCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHH
LLLARDLLSKNGVIFISIDDNEQGNLRLICDEIFGEENFEGHVHWRRRSNQPNDRSKMIG
HHHHHHHHCCCCEEEEEECCCCCCCEEEEEHHHCCCCCCCCEEEEEECCCCCCHHHHHHH
LVAEHILIYAKNSLFLKEYGVGKIGLTGNFSNPDNDPRGLWNSKPWKVGSDQSGSRYKIT
HHHHHHEEEECCCEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEE
TPDGRVLDEEWMGDEQSYLKLIEDNRIYFPKEGRGWPRKKIFKEERELEGQCANNWWNHT
CCCCCEECHHHCCCHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHCCCCHHCCCCCCC
EFGSNQKGSARLTDLFEGNQNLFSKPKPTELIEGILNVTTTDDDFYILDFFSGSATTADA
CCCCCCCCCCHHHHHHCCCHHHCCCCCHHHHHHHHHCCEECCCCEEEEEEECCCCCCCHH
VMQLNAEDQGKRKYLMVQLPESIEKNKPAYKLGYKTLDEVGRARIEKAANKIKIETNADI
EEEECCCCCCCEEEEEEECCHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHEEEEEECCCC
DYGYKLYYLETPEEKTLIELENFEPELKLITDDMISVFDNNHSSGKESILATWINEDGYG
CCCEEEEEEECCCCCCEEEEECCCCCEEEHHHHHHHHHCCCCCCCCCEEEEEEECCCCCE
LTKCSTPYKLEHYSADFIDKSLYIIDEGLEDEDVMTLIKRIENEELEINRVVVYVHSIRF
EEECCCCCEECCCCHHHHCCEEEEEECCCCHHHHHHHHHHHCCCCEEEEEEEEEEEHHHH
NVLQELRKNLKVLRNNKNVTLIERF
HHHHHHHHHHHHHCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8387444; 11677609 [H]