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The map label for this gene is msrB [H]

Identifier: 222111220

GI number: 222111220

Start: 2171237

End: 2171650

Strand: Direct

Name: msrB [H]

Synonym: Dtpsy_2028

Alternate gene names: 222111220

Gene position: 2171237-2171650 (Clockwise)

Preceding gene: 222111219

Following gene: 222111221

Centisome position: 57.19

GC content: 66.91

Gene sequence:

>414_bases
ATGACCTACCCCATCCAGAAAACCGAAGACGAATGGCAGGCGCTGCTGCAGGCCAAGGGCGCCGAGCCCGCGGCTTACCA
GGTCACGCGTCACGCGGCCACCGAGCGGCCCTTCAGCGGCAAGTACGAAGGCCACTGGGCCGACGGCAGTTACCACTGCG
TCTGCTGCGGCGCCAAGCTGTTCGACTCCGACACCAAGTTCGACGCGGGCTGCGGCTGGCCCAGCTTCTCGCTTGCCGTG
CCCGGTGCCATTCGGGAGATCGAGGACCGCAGCCACGGCATGGTGCGCACCGAGACCGTGTGTGCACAATGCGGGGCCCA
CCTGGGCCATGTCTTCCCCGACGGCCCGGCTCCTTCGGGTCTGCGCTATTGCATGAACTCCGCCTCGCTCGATTTTGAAC
CCCCGGCGCCATGA

Upstream 100 bases:

>100_bases
AAAGGTTGCTGGCGCGCCCCTTCGACGACCACCCGGGGCACGAGGCCTACGCCGGCTTTCCGCCCGACTGGGCGTCCTCC
ATCTCCATCAGCTGTTCCTC

Downstream 100 bases:

>100_bases
AACTGCTCATCGACTTCTTTCCGATCATCCTGTTCTTCGCCGCATTCAAGGTCTGGGGCATCTACGTGGCCACGGCCGTG
GCGATTGCCGCCACCGTCGT

Product: methionine-r-sulfoxide reductase

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 137; Mature: 136

Protein sequence:

>137_residues
MTYPIQKTEDEWQALLQAKGAEPAAYQVTRHAATERPFSGKYEGHWADGSYHCVCCGAKLFDSDTKFDAGCGWPSFSLAV
PGAIREIEDRSHGMVRTETVCAQCGAHLGHVFPDGPAPSGLRYCMNSASLDFEPPAP

Sequences:

>Translated_137_residues
MTYPIQKTEDEWQALLQAKGAEPAAYQVTRHAATERPFSGKYEGHWADGSYHCVCCGAKLFDSDTKFDAGCGWPSFSLAV
PGAIREIEDRSHGMVRTETVCAQCGAHLGHVFPDGPAPSGLRYCMNSASLDFEPPAP
>Mature_136_residues
TYPIQKTEDEWQALLQAKGAEPAAYQVTRHAATERPFSGKYEGHWADGSYHCVCCGAKLFDSDTKFDAGCGWPSFSLAVP
GAIREIEDRSHGMVRTETVCAQCGAHLGHVFPDGPAPSGLRYCMNSASLDFEPPAP

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=117, Percent_Identity=53.8461538461538, Blast_Score=129, Evalue=9e-31,
Organism=Homo sapiens, GI301336162, Length=117, Percent_Identity=53.8461538461538, Blast_Score=129, Evalue=9e-31,
Organism=Homo sapiens, GI73089054, Length=117, Percent_Identity=53.8461538461538, Blast_Score=129, Evalue=9e-31,
Organism=Homo sapiens, GI37620216, Length=117, Percent_Identity=53.8461538461538, Blast_Score=129, Evalue=1e-30,
Organism=Homo sapiens, GI117606353, Length=135, Percent_Identity=48.8888888888889, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1788077, Length=115, Percent_Identity=54.7826086956522, Blast_Score=129, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI17553450, Length=135, Percent_Identity=47.4074074074074, Blast_Score=126, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI115532676, Length=133, Percent_Identity=48.1203007518797, Blast_Score=125, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6319816, Length=135, Percent_Identity=41.4814814814815, Blast_Score=95, Evalue=3e-21,
Organism=Drosophila melanogaster, GI221378662, Length=123, Percent_Identity=47.9674796747967, Blast_Score=129, Evalue=5e-31,
Organism=Drosophila melanogaster, GI221378664, Length=116, Percent_Identity=51.7241379310345, Blast_Score=128, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24645799, Length=116, Percent_Identity=50, Blast_Score=125, Evalue=1e-29,
Organism=Drosophila melanogaster, GI45553335, Length=116, Percent_Identity=50, Blast_Score=125, Evalue=1e-29,
Organism=Drosophila melanogaster, GI21356369, Length=116, Percent_Identity=50, Blast_Score=125, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24645804, Length=127, Percent_Identity=44.8818897637795, Blast_Score=122, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24645801, Length=127, Percent_Identity=44.8818897637795, Blast_Score=122, Evalue=7e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 14866; Mature: 14734

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
5.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYPIQKTEDEWQALLQAKGAEPAAYQVTRHAATERPFSGKYEGHWADGSYHCVCCGAKL
CCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCEECCCCEEEEEECCHH
FDSDTKFDAGCGWPSFSLAVPGAIREIEDRSHGMVRTETVCAQCGAHLGHVFPDGPAPSG
CCCCCCCCCCCCCCCCEEECCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHH
LRYCMNSASLDFEPPAP
HHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TYPIQKTEDEWQALLQAKGAEPAAYQVTRHAATERPFSGKYEGHWADGSYHCVCCGAKL
CCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCEECCCCEEEEEECCHH
FDSDTKFDAGCGWPSFSLAVPGAIREIEDRSHGMVRTETVCAQCGAHLGHVFPDGPAPSG
CCCCCCCCCCCCCCCCEEECCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHH
LRYCMNSASLDFEPPAP
HHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA