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The map label for this gene is ygfZ [C]

Identifier: 222111181

GI number: 222111181

Start: 2125156

End: 2126091

Strand: Direct

Name: ygfZ [C]

Synonym: Dtpsy_1989

Alternate gene names: 222111181

Gene position: 2125156-2126091 (Clockwise)

Preceding gene: 222111174

Following gene: 222111185

Centisome position: 55.98

GC content: 70.51

Gene sequence:

>936_bases
ATGACCGACTCCATGCCAGTGCCCCCGTCCCTGCCTGCGGACGGCGTAGTCCCCCTGTCCCACCTTGGCGTGATCCGCGT
GGCCGGTGAAGACGCCGCCAAGTTCCTGCACGGCCAGCTGACGCAGGACTTCGCGCTGCTGGATCTGCACCACGCCCGCC
TGGCGGCGTTCCTGACCGTCAAAGGCCGCATGCAGGCCAGCTTCATCGCCTTCAAGCGCAGCGAGGCCGAGGTACTACTG
GTCTGCGCCCGCGACCTGCTGGCGCCCGCGCTCAAGCGCCTGTCGATGTTCGTGATGCGCGCCAAGGCCAAGCTGACCGA
TGCCACCGGCGACTTTGCGCTGTACGGCCTGCTGGGCGACGCCGCCCGCGCCGTGCTACCCGCTGGCGAGCCCTGGGCCA
AGGCCGATGTGGGGGATGCCAGCGTGGTGCAGCTCTACCCCGCCGAAGGGCAGCCGCGCGCACTGTGGGTAGCGCCCGCT
GGCAGCGCCGCGCCCGCTGGCGCAGCCCTGACCGAAGCGCTGTGGCTGTGGAGCGAGGTGCGCAGCGGCATCGCCACCCT
GACCGCACCCGTGGTCGAGGCCTTCGTGCCGCAGATGCTGAACTATGAATCCGTGGGCGGCGTGAACTTCAAGAAGGGCT
GCTACCCCGGCCAGGAGGTCGTGGCGCGCAGCCAGTTCCGCGGCACGCTCAAGCGGCGCACTTACCTGGCGCACGCTCCG
TCGGCCGTGGCCGTGGGTGCTGAAGTGTTTGCCGACGGTGACGCCGAACAGCCCGTGGGCACGGTGGTGCAGGTTGCGAC
CGCACCCACCGGCGGCGTGGATGCGCTGGTGTCGCTGCAGATCGCAGCCACGGGCGGCGCCCTGCGGGTGGGCGCCGCGG
ATGGCGTGGCGCTCACGCTGCTGCCGCTGCCCTACGCGCTGCTGGAAGACATATAA

Upstream 100 bases:

>100_bases
CCACAGCGCCCACGGCGATCACGATGAGCAACACCAATGCGAGGAAACGACGCACAACCCTGCAGCCTGTATGAAAGAAG
CCGGGCATCATAATTCAGCC

Downstream 100 bases:

>100_bases
GCAAAAACAGGCGCTAGCGCTTATTTGACAAGCGCTAGCAGCTATCAATAAAGAAGCCGTCAGCCCTGCAGACTGCGCCG
CATGGTGATGTGGGCAATGC

Product: folate-binding protein ygfz

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MTDSMPVPPSLPADGVVPLSHLGVIRVAGEDAAKFLHGQLTQDFALLDLHHARLAAFLTVKGRMQASFIAFKRSEAEVLL
VCARDLLAPALKRLSMFVMRAKAKLTDATGDFALYGLLGDAARAVLPAGEPWAKADVGDASVVQLYPAEGQPRALWVAPA
GSAAPAGAALTEALWLWSEVRSGIATLTAPVVEAFVPQMLNYESVGGVNFKKGCYPGQEVVARSQFRGTLKRRTYLAHAP
SAVAVGAEVFADGDAEQPVGTVVQVATAPTGGVDALVSLQIAATGGALRVGAADGVALTLLPLPYALLEDI

Sequences:

>Translated_311_residues
MTDSMPVPPSLPADGVVPLSHLGVIRVAGEDAAKFLHGQLTQDFALLDLHHARLAAFLTVKGRMQASFIAFKRSEAEVLL
VCARDLLAPALKRLSMFVMRAKAKLTDATGDFALYGLLGDAARAVLPAGEPWAKADVGDASVVQLYPAEGQPRALWVAPA
GSAAPAGAALTEALWLWSEVRSGIATLTAPVVEAFVPQMLNYESVGGVNFKKGCYPGQEVVARSQFRGTLKRRTYLAHAP
SAVAVGAEVFADGDAEQPVGTVVQVATAPTGGVDALVSLQIAATGGALRVGAADGVALTLLPLPYALLEDI
>Mature_310_residues
TDSMPVPPSLPADGVVPLSHLGVIRVAGEDAAKFLHGQLTQDFALLDLHHARLAAFLTVKGRMQASFIAFKRSEAEVLLV
CARDLLAPALKRLSMFVMRAKAKLTDATGDFALYGLLGDAARAVLPAGEPWAKADVGDASVVQLYPAEGQPRALWVAPAG
SAAPAGAALTEALWLWSEVRSGIATLTAPVVEAFVPQMLNYESVGGVNFKKGCYPGQEVVARSQFRGTLKRRTYLAHAPS
AVAVGAEVFADGDAEQPVGTVVQVATAPTGGVDALVSLQIAATGGALRVGAADGVALTLLPLPYALLEDI

Specific function: Folate-binding protein involved in regulating the level of ATP-dnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication [H]

COG id: COG0354

COG function: function code R; Predicted aminomethyltransferase related to GcvT

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tRNA-modifying ygfZ family [H]

Homologues:

Organism=Escherichia coli, GI1789265, Length=331, Percent_Identity=27.4924471299094, Blast_Score=92, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI71985951, Length=286, Percent_Identity=23.0769230769231, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017703
- InterPro:   IPR006222 [H]

Pfam domain/function: PF01571 GCV_T [H]

EC number: NA

Molecular weight: Translated: 32329; Mature: 32197

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDSMPVPPSLPADGVVPLSHLGVIRVAGEDAAKFLHGQLTQDFALLDLHHARLAAFLTV
CCCCCCCCCCCCCCCCCCHHHCCEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHEEE
KGRMQASFIAFKRSEAEVLLVCARDLLAPALKRLSMFVMRAKAKLTDATGDFALYGLLGD
CCCHHEEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHH
AARAVLPAGEPWAKADVGDASVVQLYPAEGQPRALWVAPAGSAAPAGAALTEALWLWSEV
HHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHH
RSGIATLTAPVVEAFVPQMLNYESVGGVNFKKGCYPGQEVVARSQFRGTLKRRTYLAHAP
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
SAVAVGAEVFADGDAEQPVGTVVQVATAPTGGVDALVSLQIAATGGALRVGAADGVALTL
CHHEECHHHCCCCCCCCCCCCEEEEECCCCCCCCEEEEEEEEECCCEEEECCCCCEEEEE
LPLPYALLEDI
HHCCHHHHHCC
>Mature Secondary Structure 
TDSMPVPPSLPADGVVPLSHLGVIRVAGEDAAKFLHGQLTQDFALLDLHHARLAAFLTV
CCCCCCCCCCCCCCCCCHHHCCEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHEEE
KGRMQASFIAFKRSEAEVLLVCARDLLAPALKRLSMFVMRAKAKLTDATGDFALYGLLGD
CCCHHEEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHH
AARAVLPAGEPWAKADVGDASVVQLYPAEGQPRALWVAPAGSAAPAGAALTEALWLWSEV
HHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHH
RSGIATLTAPVVEAFVPQMLNYESVGGVNFKKGCYPGQEVVARSQFRGTLKRRTYLAHAP
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
SAVAVGAEVFADGDAEQPVGTVVQVATAPTGGVDALVSLQIAATGGALRVGAADGVALTL
CHHEECHHHCCCCCCCCCCCCEEEEECCCCCCCCEEEEEEEEECCCEEEECCCCCEEEEE
LPLPYALLEDI
HHCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]