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The map label for this gene is ybhD [H]

Identifier: 222111104

GI number: 222111104

Start: 2043489

End: 2044421

Strand: Direct

Name: ybhD [H]

Synonym: Dtpsy_1911

Alternate gene names: 222111104

Gene position: 2043489-2044421 (Clockwise)

Preceding gene: 222111100

Following gene: 222111105

Centisome position: 53.82

GC content: 71.49

Gene sequence:

>933_bases
ATGAATATCTCCACACGGCAGGTCGACGCCTTCCTTGCCCTGGCGGCGCAGCGCAGCTTCACGCGCGCCGCGGCGCAGTG
CCACTTGTCGCAACCGGCCTTCAGCGCGCTCATCCGCGCGTTGGAGGACGACCTGGGTCTGCGCCTGTTCGACCGCAGCA
CGCGCCATGTGAGCCTGACGGCCGAGGGCGAGAACTTCCATGCGTCGGCGCTGCGCATTCGCGCCGAGGTGGATGCCGCG
CTGGCCACGCTGCGCGACGCCGCACTGCTGCGGCGCGGGCGCGTGTCCGTCGCGCTGCTGCCCTCGCTGGCCGCGGGGTG
GCTGCCGGGTGTGCTGGCCGGCTTTCGCGCACAGCACCCGGGCGTGGAACTGGACATTGCCGACGTGCTGTCCGAGCCTT
GCATCGAGCGCGTGGCCACGGGCAAGGCCGACTTCGCGCTGGCCGCCATCCGCGCGGACACGCCCGAGCTGCAGGCCGAG
CCCTTCTGCGAGGACGTCTTTCACCTGGTCTGCCGCGCGGACCATCCGCTCGCCCGGCAGCCCTTGCCCGCCGGCCGGCG
CAGCGCCGCCGCGCAATGGCGCGCCCTGGCCGAGTGGCCATTCATCCATCTCGCGCGGCACAGCAGCGTGCGCCAGTACC
TGGAGGCGGCCTTCCATCCCCATGCGATGCGCACGCTGATGGAAGTGGAGCAGTTGGCCACCGTCATGGGCATGGTGCGG
GCCGGGCTGGGCATCAGCGTGGTGCCCACGCTCACGCTGTTCCACTTCCAGCAGGAGGGCCTGGCCACCCGGCCGCTGGC
CCTGCCCGGGCTCACGCGGCAGATCTACCTGGTGCGCCGGCGCGACCGGGGCCTGTCGGTGGCCGCGCAGGCGCTGTACG
CACGGGTGATGCAGCAGCGGCCGATGCATGCCGAAATGCCATCAAAACAATAG

Upstream 100 bases:

>100_bases
CCATTGCAGGGGTCCTTGGGGAATGTCTCCAGGGCGCACTGTAGGCACGGCAGGTTATTCTGTGAAATAGATTGTCAAGA
TCAATTCATCTGAATATCAA

Downstream 100 bases:

>100_bases
CTGGCAGCGCTTGACGGACAAGCGCTGGAGCCCGATTTCCCTGAAACTTGCGTTCACCCGCGCCCACGGCCTGCGGGGCA
CCCCCGGTGGCACTGCACGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MNISTRQVDAFLALAAQRSFTRAAAQCHLSQPAFSALIRALEDDLGLRLFDRSTRHVSLTAEGENFHASALRIRAEVDAA
LATLRDAALLRRGRVSVALLPSLAAGWLPGVLAGFRAQHPGVELDIADVLSEPCIERVATGKADFALAAIRADTPELQAE
PFCEDVFHLVCRADHPLARQPLPAGRRSAAAQWRALAEWPFIHLARHSSVRQYLEAAFHPHAMRTLMEVEQLATVMGMVR
AGLGISVVPTLTLFHFQQEGLATRPLALPGLTRQIYLVRRRDRGLSVAAQALYARVMQQRPMHAEMPSKQ

Sequences:

>Translated_310_residues
MNISTRQVDAFLALAAQRSFTRAAAQCHLSQPAFSALIRALEDDLGLRLFDRSTRHVSLTAEGENFHASALRIRAEVDAA
LATLRDAALLRRGRVSVALLPSLAAGWLPGVLAGFRAQHPGVELDIADVLSEPCIERVATGKADFALAAIRADTPELQAE
PFCEDVFHLVCRADHPLARQPLPAGRRSAAAQWRALAEWPFIHLARHSSVRQYLEAAFHPHAMRTLMEVEQLATVMGMVR
AGLGISVVPTLTLFHFQQEGLATRPLALPGLTRQIYLVRRRDRGLSVAAQALYARVMQQRPMHAEMPSKQ
>Mature_310_residues
MNISTRQVDAFLALAAQRSFTRAAAQCHLSQPAFSALIRALEDDLGLRLFDRSTRHVSLTAEGENFHASALRIRAEVDAA
LATLRDAALLRRGRVSVALLPSLAAGWLPGVLAGFRAQHPGVELDIADVLSEPCIERVATGKADFALAAIRADTPELQAE
PFCEDVFHLVCRADHPLARQPLPAGRRSAAAQWRALAEWPFIHLARHSSVRQYLEAAFHPHAMRTLMEVEQLATVMGMVR
AGLGISVVPTLTLFHFQQEGLATRPLALPGLTRQIYLVRRRDRGLSVAAQALYARVMQQRPMHAEMPSKQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693105, Length=293, Percent_Identity=30.7167235494881, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1788748, Length=304, Percent_Identity=30.5921052631579, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI157672245, Length=289, Percent_Identity=31.1418685121107, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1788887, Length=300, Percent_Identity=27.3333333333333, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787879, Length=259, Percent_Identity=32.046332046332, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI87081904, Length=218, Percent_Identity=30.7339449541284, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1790399, Length=291, Percent_Identity=27.1477663230241, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1789204, Length=298, Percent_Identity=28.1879194630872, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787601, Length=178, Percent_Identity=29.7752808988764, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1787530, Length=267, Percent_Identity=26.9662921348315, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1788481, Length=291, Percent_Identity=25.4295532646048, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790208, Length=255, Percent_Identity=29.8039215686275, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789173, Length=161, Percent_Identity=34.1614906832298, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1790783, Length=112, Percent_Identity=34.8214285714286, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787589, Length=149, Percent_Identity=32.8859060402685, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1787806, Length=246, Percent_Identity=27.2357723577236, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI2367136, Length=261, Percent_Identity=24.904214559387, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790262, Length=274, Percent_Identity=24.4525547445255, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1788297, Length=247, Percent_Identity=21.8623481781377, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1786401, Length=175, Percent_Identity=27.4285714285714, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1788296, Length=239, Percent_Identity=27.1966527196653, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34089; Mature: 34089

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNISTRQVDAFLALAAQRSFTRAAAQCHLSQPAFSALIRALEDDLGLRLFDRSTRHVSLT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEECCCCCEEEEE
AEGENFHASALRIRAEVDAALATLRDAALLRRGRVSVALLPSLAAGWLPGVLAGFRAQHP
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHCCCC
GVELDIADVLSEPCIERVATGKADFALAAIRADTPELQAEPFCEDVFHLVCRADHPLARQ
CCEEEHHHHHHHHHHHHHHCCCCHHEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCC
PLPAGRRSAAAQWRALAEWPFIHLARHSSVRQYLEAAFHPHAMRTLMEVEQLATVMGMVR
CCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
AGLGISVVPTLTLFHFQQEGLATRPLALPGLTRQIYLVRRRDRGLSVAAQALYARVMQQR
HCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHEEEECCCCCHHHHHHHHHHHHHHHC
PMHAEMPSKQ
CCCCCCCCCC
>Mature Secondary Structure
MNISTRQVDAFLALAAQRSFTRAAAQCHLSQPAFSALIRALEDDLGLRLFDRSTRHVSLT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEECCCCCEEEEE
AEGENFHASALRIRAEVDAALATLRDAALLRRGRVSVALLPSLAAGWLPGVLAGFRAQHP
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHCCCC
GVELDIADVLSEPCIERVATGKADFALAAIRADTPELQAEPFCEDVFHLVCRADHPLARQ
CCEEEHHHHHHHHHHHHHHCCCCHHEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCC
PLPAGRRSAAAQWRALAEWPFIHLARHSSVRQYLEAAFHPHAMRTLMEVEQLATVMGMVR
CCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
AGLGISVVPTLTLFHFQQEGLATRPLALPGLTRQIYLVRRRDRGLSVAAQALYARVMQQR
HCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHEEEECCCCCHHHHHHHHHHHHHHHC
PMHAEMPSKQ
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]