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The map label for this gene is idnR [H]

Identifier: 222111070

GI number: 222111070

Start: 1998726

End: 1999751

Strand: Direct

Name: idnR [H]

Synonym: Dtpsy_1877

Alternate gene names: 222111070

Gene position: 1998726-1999751 (Clockwise)

Preceding gene: 222111063

Following gene: 222111072

Centisome position: 52.65

GC content: 71.15

Gene sequence:

>1026_bases
TTGACCGCCAACCGACGACCGCGCCGCTCCAGCGGCCGCATCACCCTGAACGACGTGGCAGGCGCCGCCGGCGTGAGTCC
CATCACCGTGTCGCGTGCCCTGCGCGGCGAACGCACCGTGGACCCCGCGTTGGCCGAACGCGTACGCGAGGCGGCCGATC
GGCTGGGCTACGTACCCGACCCGGCCGCGCGCGCGCTGGCGTCGCAGCGCAGCACGCAGGTGCTGGTGCTGGTGCCGCTG
CTGTCCAACGCGCTGTTCGTGGATCTGCTGGAGGCGGTGCACCGCACGCTGTTCCCCAAGGGCTTTCAGCCGCTCATCGG
CGTGACCCACTACGACAGCGCCGAGGAAGAGTTGCTGCTGCGCACCTACCTGCCCCACCGCCCCGCCGGCCTGCTGGTGA
CGGGGTTCGACCGCAGCGAGGCCGCACGCCAGCTCATCGTGCACAGCGGCGTGCCGTGCGTGCACCTCATGGAGACCAGC
GCCGCGCCTGGTGTGGCCTGCGTGGGCTTTTCGCAGCAGGACGCGGGCGCCACCATCACGCGCCACCTGCTGGAACGCGG
GCGTAAGCGCATCGCCTTTTGCGCCGCGCAACTGGACCCGCGCGTGCTGCAGCGCGCCGAAGGGTACCGGCGCACCCTGC
GCGAAGCGGGCCTGTACGATCCGCGCCTGGAGTTGCTAAGCCCCGAGCGCTCTTCCATCGCCCTGGGCGCCCGGCTGTTC
GAGGACCTGGTGCAACGCATGCCCGACGTGGACGCCATCTTCTTTTGCAACGACGACATTGCCCAGGGCGGGCTGCTGGC
GGCCAACCGCATGCGCATCGACGTGCCGGGCCGCATCGCCGTCGCGGGATTCAACGACTTGGCCGGCAGCGCGCAGATGG
TGCCGCCGCTGACCACCATCCGCACACCGCGCAGCGAAGTCGGCCGCGCCGGCGCCGACATGCTGCTGGGCCTGATGCGC
GGCACGCTGGCGCAGCCGCAGTGCGTGCAGCTGGACTACGAGCTGATCGTGCGCGAGAGTACGTGA

Upstream 100 bases:

>100_bases
ATGGGGAGAAGCTACTCCCTCCCCACAAACCCGCGAAAACCCCATGAAAGATAGCGCTATCTTAAGGGACAATTTTGGCC
AGAATTCCTAGGAATAACCC

Downstream 100 bases:

>100_bases
ACAAGGGTGCAGTGCAGCGCAGTGCGCTACAGCTTTGGTAGCTGTTCGCGCTTGCAAATCAAGCACTCAAGGCAAAAAAG
TACCTGAATCCCCATTCAAA

Product: LacI family transcriptional regulator

Products: NA

Alternate protein names: L-idonate regulatory protein [H]

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MTANRRPRRSSGRITLNDVAGAAGVSPITVSRALRGERTVDPALAERVREAADRLGYVPDPAARALASQRSTQVLVLVPL
LSNALFVDLLEAVHRTLFPKGFQPLIGVTHYDSAEEELLLRTYLPHRPAGLLVTGFDRSEAARQLIVHSGVPCVHLMETS
AAPGVACVGFSQQDAGATITRHLLERGRKRIAFCAAQLDPRVLQRAEGYRRTLREAGLYDPRLELLSPERSSIALGARLF
EDLVQRMPDVDAIFFCNDDIAQGGLLAANRMRIDVPGRIAVAGFNDLAGSAQMVPPLTTIRTPRSEVGRAGADMLLGLMR
GTLAQPQCVQLDYELIVREST

Sequences:

>Translated_341_residues
MTANRRPRRSSGRITLNDVAGAAGVSPITVSRALRGERTVDPALAERVREAADRLGYVPDPAARALASQRSTQVLVLVPL
LSNALFVDLLEAVHRTLFPKGFQPLIGVTHYDSAEEELLLRTYLPHRPAGLLVTGFDRSEAARQLIVHSGVPCVHLMETS
AAPGVACVGFSQQDAGATITRHLLERGRKRIAFCAAQLDPRVLQRAEGYRRTLREAGLYDPRLELLSPERSSIALGARLF
EDLVQRMPDVDAIFFCNDDIAQGGLLAANRMRIDVPGRIAVAGFNDLAGSAQMVPPLTTIRTPRSEVGRAGADMLLGLMR
GTLAQPQCVQLDYELIVREST
>Mature_340_residues
TANRRPRRSSGRITLNDVAGAAGVSPITVSRALRGERTVDPALAERVREAADRLGYVPDPAARALASQRSTQVLVLVPLL
SNALFVDLLEAVHRTLFPKGFQPLIGVTHYDSAEEELLLRTYLPHRPAGLLVTGFDRSEAARQLIVHSGVPCVHLMETSA
APGVACVGFSQQDAGATITRHLLERGRKRIAFCAAQLDPRVLQRAEGYRRTLREAGLYDPRLELLSPERSSIALGARLFE
DLVQRMPDVDAIFFCNDDIAQGGLLAANRMRIDVPGRIAVAGFNDLAGSAQMVPPLTTIRTPRSEVGRAGADMLLGLMRG
TLAQPQCVQLDYELIVREST

Specific function: Idn operon regulator. May repress gntKU and gntT genes when growing on L-idonate [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790715, Length=332, Percent_Identity=31.0240963855422, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI48994940, Length=323, Percent_Identity=30.9597523219814, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1790369, Length=344, Percent_Identity=29.9418604651163, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI1790194, Length=331, Percent_Identity=29.607250755287, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI1789202, Length=299, Percent_Identity=29.7658862876254, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1787948, Length=334, Percent_Identity=26.0479041916168, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1789068, Length=301, Percent_Identity=28.9036544850498, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1788474, Length=309, Percent_Identity=27.831715210356, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787906, Length=325, Percent_Identity=28.9230769230769, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1786540, Length=318, Percent_Identity=26.4150943396226, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1787580, Length=315, Percent_Identity=24.1269841269841, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37085; Mature: 36954

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTANRRPRRSSGRITLNDVAGAAGVSPITVSRALRGERTVDPALAERVREAADRLGYVPD
CCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCC
PAARALASQRSTQVLVLVPLLSNALFVDLLEAVHRTLFPKGFQPLIGVTHYDSAEEELLL
HHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCEECCCCHHHHHHH
RTYLPHRPAGLLVTGFDRSEAARQLIVHSGVPCVHLMETSAAPGVACVGFSQQDAGATIT
HHHCCCCCCCEEEECCCHHHHHHHHHHHCCCCEEEEEECCCCCCEEEECCCCCCCCHHHH
RHLLERGRKRIAFCAAQLDPRVLQRAEGYRRTLREAGLYDPRLELLSPERSSIALGARLF
HHHHHHCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHH
EDLVQRMPDVDAIFFCNDDIAQGGLLAANRMRIDVPGRIAVAGFNDLAGSAQMVPPLTTI
HHHHHHCCCCCEEEEECCCCCCCCEEEECEEEEECCCEEEEECCHHHCCCCCCCCCHHHH
RTPRSEVGRAGADMLLGLMRGTLAQPQCVQLDYELIVREST
CCCHHHHCCCHHHHHHHHHHHCCCCCCEEEECEEEEEEECC
>Mature Secondary Structure 
TANRRPRRSSGRITLNDVAGAAGVSPITVSRALRGERTVDPALAERVREAADRLGYVPD
CCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCC
PAARALASQRSTQVLVLVPLLSNALFVDLLEAVHRTLFPKGFQPLIGVTHYDSAEEELLL
HHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCEECCCCHHHHHHH
RTYLPHRPAGLLVTGFDRSEAARQLIVHSGVPCVHLMETSAAPGVACVGFSQQDAGATIT
HHHCCCCCCCEEEECCCHHHHHHHHHHHCCCCEEEEEECCCCCCEEEECCCCCCCCHHHH
RHLLERGRKRIAFCAAQLDPRVLQRAEGYRRTLREAGLYDPRLELLSPERSSIALGARLF
HHHHHHCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHH
EDLVQRMPDVDAIFFCNDDIAQGGLLAANRMRIDVPGRIAVAGFNDLAGSAQMVPPLTTI
HHHHHHCCCCCEEEEECCCCCCCCEEEECEEEEECCCEEEEECCHHHCCCCCCCCCHHHH
RTPRSEVGRAGADMLLGLMRGTLAQPQCVQLDYELIVREST
CCCHHHHCCCHHHHHHHHHHHCCCCCCEEEECEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 9658018 [H]