Click here to switch to the map view.

The map label for this gene is 222111047

Identifier: 222111047

GI number: 222111047

Start: 1975591

End: 1976052

Strand: Direct

Name: 222111047

Synonym: Dtpsy_1854

Alternate gene names: NA

Gene position: 1975591-1976052 (Clockwise)

Preceding gene: 222111046

Following gene: 222111048

Centisome position: 52.04

GC content: 63.85

Gene sequence:

>462_bases
ATGACACGCCCCTTCAAAGTGCTGGGCATCCAGCAGGTGGCCATCGGCGGCACCGACAAGCAGCGCATGAAGACCTTGTG
GGTGGACATGCTCGGCCTCACGCAGACGGGTACCTTCCAGAGCGAGCGAGAGAACGTGGACGAGGACATCCTTGCCATGG
GGCAGGGCGCCTTCAAGGTGGAGGTGGACATCATGCAGCCCCTGGACATCGAGAAAAAGCCTGCCGTGCACGCCACGCCG
CTGAACCACATCGGCCTGTGGATCGATGACCTGCCCAAGGCGGTGGAATGGCTGACCGCACAGGGTGTGCGCTTTGCGCC
CGGGGGCATCCGCAAAGGCGCGGCGGGCTACGACATCACCTTCCTGCATCCCAAGAGCAATGACGAATTCCCGATCGCCG
GGGAGGGTGTCCTGATCGAACTGGTGCAGGCGCCGCCCGAGGTGATCGCGGCGTTGGGTTGA

Upstream 100 bases:

>100_bases
AATCGCTGGCGGTGGATCAGGTCATCCTGGAATTTCAATGAAAACAGCATCTAACGCTTGCCCTGCAAGCGCTAGCAGCT
ATCAATAAAGGAGTAAATGG

Downstream 100 bases:

>100_bases
AAAAGACAAACTTCGACGCAACCGCCTGACTGCTGAAAAACAAGAGAGCCCTGGTCCATGCGACCAGGGCTTTTTTTATG
GTCATGCCGCATCTTCAGCA

Product: lactoylglutathione lyase

Products: glutathione; methylglyoxal

Alternate protein names: Methylmalonyl-CoA Epimerase; Glyoxalase/Bleomycin Resistance Protein/Dioxygenase

Number of amino acids: Translated: 153; Mature: 152

Protein sequence:

>153_residues
MTRPFKVLGIQQVAIGGTDKQRMKTLWVDMLGLTQTGTFQSERENVDEDILAMGQGAFKVEVDIMQPLDIEKKPAVHATP
LNHIGLWIDDLPKAVEWLTAQGVRFAPGGIRKGAAGYDITFLHPKSNDEFPIAGEGVLIELVQAPPEVIAALG

Sequences:

>Translated_153_residues
MTRPFKVLGIQQVAIGGTDKQRMKTLWVDMLGLTQTGTFQSERENVDEDILAMGQGAFKVEVDIMQPLDIEKKPAVHATP
LNHIGLWIDDLPKAVEWLTAQGVRFAPGGIRKGAAGYDITFLHPKSNDEFPIAGEGVLIELVQAPPEVIAALG
>Mature_152_residues
TRPFKVLGIQQVAIGGTDKQRMKTLWVDMLGLTQTGTFQSERENVDEDILAMGQGAFKVEVDIMQPLDIEKKPAVHATPL
NHIGLWIDDLPKAVEWLTAQGVRFAPGGIRKGAAGYDITFLHPKSNDEFPIAGEGVLIELVQAPPEVIAALG

Specific function: Unknown

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.4.1.5

Molecular weight: Translated: 16657; Mature: 16526

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRPFKVLGIQQVAIGGTDKQRMKTLWVDMLGLTQTGTFQSERENVDEDILAMGQGAFKV
CCCCEEEEEEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHCCCCEEE
EVDIMQPLDIEKKPAVHATPLNHIGLWIDDLPKAVEWLTAQGVRFAPGGIRKGAAGYDIT
EEEEECCCCCCCCCCEECCCCCHHCCCHHHHHHHHHHHHHCCCEECCCCCCCCCCCCEEE
FLHPKSNDEFPIAGEGVLIELVQAPPEVIAALG
EEECCCCCCCCCCCCCEEEEEECCCHHHHHCCC
>Mature Secondary Structure 
TRPFKVLGIQQVAIGGTDKQRMKTLWVDMLGLTQTGTFQSERENVDEDILAMGQGAFKV
CCCEEEEEEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHCCCCEEE
EVDIMQPLDIEKKPAVHATPLNHIGLWIDDLPKAVEWLTAQGVRFAPGGIRKGAAGYDIT
EEEEECCCCCCCCCCEECCCCCHHCCCHHHHHHHHHHHHHCCCEECCCCCCCCCCCCEEE
FLHPKSNDEFPIAGEGVLIELVQAPPEVIAALG
EEECCCCCCCCCCCCCEEEEEECCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (R)-S-lactoylglutathione

Specific reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA