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The map label for this gene is gltS [H]

Identifier: 222110785

GI number: 222110785

Start: 1682682

End: 1683896

Strand: Direct

Name: gltS [H]

Synonym: Dtpsy_1590

Alternate gene names: 222110785

Gene position: 1682682-1683896 (Clockwise)

Preceding gene: 222110782

Following gene: 222110786

Centisome position: 44.32

GC content: 66.17

Gene sequence:

>1215_bases
ATGGATATACAGTTCAGCACCTACTACACCCTGATCTTCGCGGCCATCGTGCTGCTGGTGGGCAAGTTCCTCGTGCAGCG
CATCCGCTGGCTGCGCGAATTCAACATTCCGGAACCCGTGGCGGGCGGCCTGGTGGCGGCGCTCATCTCCTGGGGGCTGA
ACGCCGCGTTCGATGTGCGTGCGTCGTTCGACACCGGCCTGCAGACCGCCTTCATGCTGGTGTTCTTCTCCTCCATCGGG
CTGAGCGCCAACTTCCTCAAGCTGCGCGAGGGCGGCATGGGGCTGATCGTCTTCCTGCTGGTCGTGGTGGTGTTCATCGG
CGTGCAGAACAGCGTGGGCGTGGCGCTGGCCACCGCGCTGGGGCTGGACCCGCTGATCGGCCTGATCGCGGGCTCCATCA
CTTTGGTGGGCGGGCACGGCACGGCCGGGGCCTGGGGCTCGGTGCTGGAAAACGACCACGGCATCCCTGGCGCCATCACC
TTGGGCATTGCCTGTGCCACCTTCGGCCTGGTCATCGGCGGGCTGATCGGCGGGCCGCTGGCCAAATGGCTGATCCAGCG
CCACGGGCTGAAGCACCCGCAGGGCACGGGCGATGCCGGCGCGCTGGAGGCGGGCACGCCCAACTTCGAGTTCCCGCACA
AGACGCGCCTGATCACCGCGGACGCGGCCATCGAGACCATGGCCCTGTTTGCCGGCTGCCTGGCCTTTGCCGAGTTCATG
AGCCAGTTGACGAAGGGCACGGCGCTGCAACTGCCCACCTTCGTGTGGGCGCTGGGCGGGGGCGTGCTGATCCGCAACGT
GCTGGACTACGTCTTCAACTTCGAGGTGTTCGACCGCGCCATCGACGTGTTCGGCAACACCGGGCTGTCCGTCTACCTGG
CGATCGCGCTGCTGTCGCTCAAGCTGTGGGAGCTGGCCGGGCTGGCGGGTCCGCTGGTCATCATCCTGGGCGTGCAGACG
CTGGTCATGGCGGCCTACGCGGGCTTCGTCACCTTCCGCCTGATGGGAAGCAACTACGATGCGGCCGTGCTCTGTGCGGG
GCATTGCGGCTTCGGCATGGGCGCCACGCCCACGGCGGTGGCCAACATGCAGGCCATTACCAACCAGTACGGCGCGTCGC
ACAAGGCTTTCCTGATCGTGCCCATGGTGGGCGCGTTCTTCATCGACCTGGTCAATGCCGTGGCCATCCAGGTCTTCATC
AACGTGTTTGGCTAA

Upstream 100 bases:

>100_bases
CAGGGCGCTTAGCGCGCGTGTGGTTTGTGCGCCTGCCGCTTCCACCGCCAGCGGCACGGCTGGGTTGCGTCCGCCGGCGT
GGTTCTTCCTTTGAGATCAC

Downstream 100 bases:

>100_bases
GCGCCCACCACGGCGCGGAGGGCAGGCGGTGCGTACAGGATTCGGACTGATCGGGCTGCTGCTGGCCCTGGCCCTCGTGG
CCGTGCTGGTCAAGAAGCAG

Product: sodium/glutamate symporter

Products: Na (I) [Cytoplasm]; L-glutamate [Cytoplasm] [C]

Alternate protein names: Glutamate permease [H]

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MDIQFSTYYTLIFAAIVLLVGKFLVQRIRWLREFNIPEPVAGGLVAALISWGLNAAFDVRASFDTGLQTAFMLVFFSSIG
LSANFLKLREGGMGLIVFLLVVVVFIGVQNSVGVALATALGLDPLIGLIAGSITLVGGHGTAGAWGSVLENDHGIPGAIT
LGIACATFGLVIGGLIGGPLAKWLIQRHGLKHPQGTGDAGALEAGTPNFEFPHKTRLITADAAIETMALFAGCLAFAEFM
SQLTKGTALQLPTFVWALGGGVLIRNVLDYVFNFEVFDRAIDVFGNTGLSVYLAIALLSLKLWELAGLAGPLVIILGVQT
LVMAAYAGFVTFRLMGSNYDAAVLCAGHCGFGMGATPTAVANMQAITNQYGASHKAFLIVPMVGAFFIDLVNAVAIQVFI
NVFG

Sequences:

>Translated_404_residues
MDIQFSTYYTLIFAAIVLLVGKFLVQRIRWLREFNIPEPVAGGLVAALISWGLNAAFDVRASFDTGLQTAFMLVFFSSIG
LSANFLKLREGGMGLIVFLLVVVVFIGVQNSVGVALATALGLDPLIGLIAGSITLVGGHGTAGAWGSVLENDHGIPGAIT
LGIACATFGLVIGGLIGGPLAKWLIQRHGLKHPQGTGDAGALEAGTPNFEFPHKTRLITADAAIETMALFAGCLAFAEFM
SQLTKGTALQLPTFVWALGGGVLIRNVLDYVFNFEVFDRAIDVFGNTGLSVYLAIALLSLKLWELAGLAGPLVIILGVQT
LVMAAYAGFVTFRLMGSNYDAAVLCAGHCGFGMGATPTAVANMQAITNQYGASHKAFLIVPMVGAFFIDLVNAVAIQVFI
NVFG
>Mature_404_residues
MDIQFSTYYTLIFAAIVLLVGKFLVQRIRWLREFNIPEPVAGGLVAALISWGLNAAFDVRASFDTGLQTAFMLVFFSSIG
LSANFLKLREGGMGLIVFLLVVVVFIGVQNSVGVALATALGLDPLIGLIAGSITLVGGHGTAGAWGSVLENDHGIPGAIT
LGIACATFGLVIGGLIGGPLAKWLIQRHGLKHPQGTGDAGALEAGTPNFEFPHKTRLITADAAIETMALFAGCLAFAEFM
SQLTKGTALQLPTFVWALGGGVLIRNVLDYVFNFEVFDRAIDVFGNTGLSVYLAIALLSLKLWELAGLAGPLVIILGVQT
LVMAAYAGFVTFRLMGSNYDAAVLCAGHCGFGMGATPTAVANMQAITNQYGASHKAFLIVPMVGAFFIDLVNAVAIQVFI
NVFG

Specific function: Catalyzes the sodium-dependent uptake of extracellular glutamate [H]

COG id: COG0786

COG function: function code E; Na+/glutamate symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gltS symporter family [H]

Homologues:

Organism=Escherichia coli, GI1790085, Length=380, Percent_Identity=52.1052631578947, Blast_Score=342, Evalue=3e-95,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004445 [H]

Pfam domain/function: PF03616 Glt_symporter [H]

EC number: NA

Molecular weight: Translated: 42409; Mature: 42409

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS00196 COPPER_BLUE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIQFSTYYTLIFAAIVLLVGKFLVQRIRWLREFNIPEPVAGGLVAALISWGLNAAFDVR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEE
ASFDTGLQTAFMLVFFSSIGLSANFLKLREGGMGLIVFLLVVVVFIGVQNSVGVALATAL
CCCCCHHHHHHHHHHHHHHCCCCHHHHECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHH
GLDPLIGLIAGSITLVGGHGTAGAWGSVLENDHGIPGAITLGIACATFGLVIGGLIGGPL
CHHHHHHHHHCCEEEEECCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AKWLIQRHGLKHPQGTGDAGALEAGTPNFEFPHKTRLITADAAIETMALFAGCLAFAEFM
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHH
SQLTKGTALQLPTFVWALGGGVLIRNVLDYVFNFEVFDRAIDVFGNTGLSVYLAIALLSL
HHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
KLWELAGLAGPLVIILGVQTLVMAAYAGFVTFRLMGSNYDAAVLCAGHCGFGMGATPTAV
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEEECCCCCCCCCCCHHH
ANMQAITNQYGASHKAFLIVPMVGAFFIDLVNAVAIQVFINVFG
HHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDIQFSTYYTLIFAAIVLLVGKFLVQRIRWLREFNIPEPVAGGLVAALISWGLNAAFDVR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEE
ASFDTGLQTAFMLVFFSSIGLSANFLKLREGGMGLIVFLLVVVVFIGVQNSVGVALATAL
CCCCCHHHHHHHHHHHHHHCCCCHHHHECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHH
GLDPLIGLIAGSITLVGGHGTAGAWGSVLENDHGIPGAITLGIACATFGLVIGGLIGGPL
CHHHHHHHHHCCEEEEECCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AKWLIQRHGLKHPQGTGDAGALEAGTPNFEFPHKTRLITADAAIETMALFAGCLAFAEFM
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHH
SQLTKGTALQLPTFVWALGGGVLIRNVLDYVFNFEVFDRAIDVFGNTGLSVYLAIALLSL
HHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
KLWELAGLAGPLVIILGVQTLVMAAYAGFVTFRLMGSNYDAAVLCAGHCGFGMGATPTAV
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEEECCCCCCCCCCCHHH
ANMQAITNQYGASHKAFLIVPMVGAFFIDLVNAVAIQVFINVFG
HHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; L-glutamate [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + L-glutamate [Periplasm] = Na (I) [Cytoplasm] + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]