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The map label for this gene is glmM

Identifier: 222110675

GI number: 222110675

Start: 1548905

End: 1550239

Strand: Direct

Name: glmM

Synonym: Dtpsy_1477

Alternate gene names: 222110675

Gene position: 1548905-1550239 (Clockwise)

Preceding gene: 222110674

Following gene: 222110677

Centisome position: 40.8

GC content: 66.44

Gene sequence:

>1335_bases
ATGACCCGCAAGTATTTCGGCACCGATGGCATCCGCGGCACGGTGGGACAGTCGCCCATCACCCCCGACTTCGCGCTGCG
CTTGGCACATGCGGTAGGGCGTGTGCTGCGCCGCACGCAGGAGCGTCCAACGGTGCTCATCGGCAAGGACACGCGCATCT
CCGGCTACATGCTGGAAAGCGCGCTGGAATCGGGCTTCAACTCGGCGGGTGTGGATGTCGTGCTGCTGGGGCCGCTGCCC
ACGCCGGGCGTGGCCTACCTCACGCGTGCCCAGCGTGCGAGCCTGGGCGTGGTCATCAGCGCCAGCCACAATCCCTACCC
CGACAACGGCATCAAGTTCTTCAGTGCGCAAGGCACCAAGCTGCCCGACGCATGGGAAGAAGAGGTGGAAGCCGCCCTGG
AGCAACCGCCCGTGTGGGCCGATTCCGCATCGCTGGGCAAGACGCGACGGCTGGATGACGCCGCCGGCCGTTACATCGAA
TTCTGCAAGAGCACTTTTGCCAACGACCTCACGCTGCGGGGCCTGAAGATCGTCGTGGATGCCGCACATGGCGCGGCTTA
TCACATCGCGCCCAAGGTGTTCCATGAACTGGGGGCCGAGGTCCTGGCGATCGGGTGCGCGCCCGATGGACTCAACATCA
ACCATCAGGTGGGCGCCACGCATCCGGACGCGCTGGTGCGAGCCGTGCGTGCCAACCATGCTGACTACGGCATTGCGCTG
GACGGCGACGCGGACCGCGTGCAAATGGTGGATGCGGCGGGGCGGCTTTTCAACGGTGACGAATTGCTCTACGTGATGGT
CGCCGCCCGGCTGGCGCGCGACGAGCATGTGCCCGGCGTGGTCGGCACCTTGATGACCAACATGGCCGTGGAAGAGGCCC
TGCAGCGGCGCGGCGTGAAATTCATGCGCGCCAAGGTAGGGGACCGCTATGTGCTGGAAGAACTCCAGCGCCAGCATTGG
CTGTTGGGCGGGGAGGGCTCGGGCCACCTGCTCGCGCTGGACCGGCACACCACGGGCGATGGCCTGATCAGCGCGTTGCA
GGTGTTGCAGGCGTGCGTGCGCAGCGGCAAAACGCTGGCACAGCTGCTCGCGGACGTGCCGTTGTTTCCTCAGGTGTTGC
TCAACGTACGCTTGAACCCGGGCCAGGACTGGAAAACCAACCCTGTGCTCGCGGATGCCATCCGCGACGCAGAGGCCGAA
TTGGGCGCCCATGGCCGCGTGCTGGTGCGCGCCAGCGGCACGGAGCCACTGTTGCGCGTGATGGTGGAGGCACGTGAGGC
CGAGCAGGCGAACCGCTGCGCACAACGCATAGCAGACGCAGCGCGTGCGGGCTGA

Upstream 100 bases:

>100_bases
TGTGCATGACGTACGCGACACCGTGGCGGCGCTGGCGGTGTGGAGCGCGATGCGGCAGCAGGACACCGGCGCCGCCATTT
CCCAGTAATCAAGGAATTTC

Downstream 100 bases:

>100_bases
TTTGCTATTGTTTTTGTAGCTGCTTGCGCTTGATAGGCGGGCGCTACAGGCACTTTTGAGTGTTCATTCAGGCAGGGCGC
TGCAGCAAATACTGCTGCAG

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MTRKYFGTDGIRGTVGQSPITPDFALRLAHAVGRVLRRTQERPTVLIGKDTRISGYMLESALESGFNSAGVDVVLLGPLP
TPGVAYLTRAQRASLGVVISASHNPYPDNGIKFFSAQGTKLPDAWEEEVEAALEQPPVWADSASLGKTRRLDDAAGRYIE
FCKSTFANDLTLRGLKIVVDAAHGAAYHIAPKVFHELGAEVLAIGCAPDGLNINHQVGATHPDALVRAVRANHADYGIAL
DGDADRVQMVDAAGRLFNGDELLYVMVAARLARDEHVPGVVGTLMTNMAVEEALQRRGVKFMRAKVGDRYVLEELQRQHW
LLGGEGSGHLLALDRHTTGDGLISALQVLQACVRSGKTLAQLLADVPLFPQVLLNVRLNPGQDWKTNPVLADAIRDAEAE
LGAHGRVLVRASGTEPLLRVMVEAREAEQANRCAQRIADAARAG

Sequences:

>Translated_444_residues
MTRKYFGTDGIRGTVGQSPITPDFALRLAHAVGRVLRRTQERPTVLIGKDTRISGYMLESALESGFNSAGVDVVLLGPLP
TPGVAYLTRAQRASLGVVISASHNPYPDNGIKFFSAQGTKLPDAWEEEVEAALEQPPVWADSASLGKTRRLDDAAGRYIE
FCKSTFANDLTLRGLKIVVDAAHGAAYHIAPKVFHELGAEVLAIGCAPDGLNINHQVGATHPDALVRAVRANHADYGIAL
DGDADRVQMVDAAGRLFNGDELLYVMVAARLARDEHVPGVVGTLMTNMAVEEALQRRGVKFMRAKVGDRYVLEELQRQHW
LLGGEGSGHLLALDRHTTGDGLISALQVLQACVRSGKTLAQLLADVPLFPQVLLNVRLNPGQDWKTNPVLADAIRDAEAE
LGAHGRVLVRASGTEPLLRVMVEAREAEQANRCAQRIADAARAG
>Mature_443_residues
TRKYFGTDGIRGTVGQSPITPDFALRLAHAVGRVLRRTQERPTVLIGKDTRISGYMLESALESGFNSAGVDVVLLGPLPT
PGVAYLTRAQRASLGVVISASHNPYPDNGIKFFSAQGTKLPDAWEEEVEAALEQPPVWADSASLGKTRRLDDAAGRYIEF
CKSTFANDLTLRGLKIVVDAAHGAAYHIAPKVFHELGAEVLAIGCAPDGLNINHQVGATHPDALVRAVRANHADYGIALD
GDADRVQMVDAAGRLFNGDELLYVMVAARLARDEHVPGVVGTLMTNMAVEEALQRRGVKFMRAKVGDRYVLEELQRQHWL
LGGEGSGHLLALDRHTTGDGLISALQVLQACVRSGKTLAQLLADVPLFPQVLLNVRLNPGQDWKTNPVLADAIRDAEAEL
GAHGRVLVRASGTEPLLRVMVEAREAEQANRCAQRIADAARAG

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Escherichia coli, GI1789566, Length=446, Percent_Identity=56.2780269058296, Blast_Score=476, Evalue=1e-135,
Organism=Escherichia coli, GI1788361, Length=448, Percent_Identity=27.9017857142857, Blast_Score=116, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI71993870, Length=294, Percent_Identity=26.530612244898, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71993878, Length=301, Percent_Identity=25.2491694352159, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_ACIET (B9MI07)

Other databases:

- EMBL:   CP001392
- RefSeq:   YP_002552939.1
- ProteinModelPortal:   B9MI07
- GeneID:   7385119
- GenomeReviews:   CP001392_GR
- KEGG:   dia:Dtpsy_1477
- ProtClustDB:   PRK10887
- HAMAP:   MF_01554_B
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- InterPro:   IPR006352
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509
- TIGRFAMs:   TIGR01455

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 47793; Mature: 47662

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS00710 PGM_PMM

Important sites: ACT_SITE 102-102

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRKYFGTDGIRGTVGQSPITPDFALRLAHAVGRVLRRTQERPTVLIGKDTRISGYMLES
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHH
ALESGFNSAGVDVVLLGPLPTPGVAYLTRAQRASLGVVISASHNPYPDNGIKFFSAQGTK
HHHCCCCCCCCCEEEECCCCCCCHHHHHHHHHCCEEEEEECCCCCCCCCCEEEEECCCCC
LPDAWEEEVEAALEQPPVWADSASLGKTRRLDDAAGRYIEFCKSTFANDLTLRGLKIVVD
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEECCEEEEEE
AAHGAAYHIAPKVFHELGAEVLAIGCAPDGLNINHQVGATHPDALVRAVRANHADYGIAL
CCCCCEEEHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEE
DGDADRVQMVDAAGRLFNGDELLYVMVAARLARDEHVPGVVGTLMTNMAVEEALQRRGVK
CCCCCHHHHHHHHCCEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHH
FMRAKVGDRYVLEELQRQHWLLGGEGSGHLLALDRHTTGDGLISALQVLQACVRSGKTLA
HHHHHCCCHHHHHHHHHHHCEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCHHHH
QLLADVPLFPQVLLNVRLNPGQDWKTNPVLADAIRDAEAELGAHGRVLVRASGTEPLLRV
HHHHCCCHHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHH
MVEAREAEQANRCAQRIADAARAG
HHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TRKYFGTDGIRGTVGQSPITPDFALRLAHAVGRVLRRTQERPTVLIGKDTRISGYMLES
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHH
ALESGFNSAGVDVVLLGPLPTPGVAYLTRAQRASLGVVISASHNPYPDNGIKFFSAQGTK
HHHCCCCCCCCCEEEECCCCCCCHHHHHHHHHCCEEEEEECCCCCCCCCCEEEEECCCCC
LPDAWEEEVEAALEQPPVWADSASLGKTRRLDDAAGRYIEFCKSTFANDLTLRGLKIVVD
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEECCEEEEEE
AAHGAAYHIAPKVFHELGAEVLAIGCAPDGLNINHQVGATHPDALVRAVRANHADYGIAL
CCCCCEEEHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEE
DGDADRVQMVDAAGRLFNGDELLYVMVAARLARDEHVPGVVGTLMTNMAVEEALQRRGVK
CCCCCHHHHHHHHCCEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHH
FMRAKVGDRYVLEELQRQHWLLGGEGSGHLLALDRHTTGDGLISALQVLQACVRSGKTLA
HHHHHCCCHHHHHHHHHHHCEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCHHHH
QLLADVPLFPQVLLNVRLNPGQDWKTNPVLADAIRDAEAELGAHGRVLVRASGTEPLLRV
HHHHCCCHHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHH
MVEAREAEQANRCAQRIADAARAG
HHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA