Click here to switch to the map view.

The map label for this gene is ubiG [H]

Identifier: 222110598

GI number: 222110598

Start: 1466835

End: 1467548

Strand: Direct

Name: ubiG [H]

Synonym: Dtpsy_1398

Alternate gene names: 222110598

Gene position: 1466835-1467548 (Clockwise)

Preceding gene: 222110597

Following gene: 222110599

Centisome position: 38.64

GC content: 61.48

Gene sequence:

>714_bases
ATGACTGTTTCTGTAAACGCCGATCCCGCTGAGTTGGCCAAGTTTTCGGAACTGGCCCATCGCTGGTGGGACCCCGACAG
CGAATTCCGTCCGCTGCACCAAATCAATCCGTTGCGGCTGGATTGGATCAATCAACTCTCGCCTCTGGAAGGGCGCAAGG
TTCTCGACGTGGGGTGCGGCGGGGGAATTCTGTCGGACTCCATGGCCCGCAAGGGGGCAGAAGTCACGGGGATCGACCTG
GCGTCCAAGGCATTGCGCGTGGCGCGGCTCCATGCCCTGGAGGCGGAAACGCCGCGCGTACAGTACCGGGAGATCAGCGT
CGAGGAGTTGGCAAACGAGTGTCCTGGGTCGTTCGACACGGTCACCTGCATGGAGATGCTGGAGCACGTGCCCGATCCCC
AGTCGGTCGTGGCCGCATGCGCGCGCCTCGTCAAGCCAGGCGGATGGGTGTTCTTCTCTACGATCAACCGGAATGCGAAG
GCCTTTGCGTTGGCGATCGTTGGGGCGGAATACCTGCTCAAGATGCTGCCCCAGGGAACGCATGAGTACGCCAAATTCAT
CCGCCCTAGTGAGCTGGCATCCGCATGCCGCCAGGCGGGCCTTGATGTGTTGCATACGCGCGGCATGCAGTACAACCCCG
TAACCGGCCGCTATTGGCTGAGCGGGGATACCGATGTGAATTACCTGTTCGCTACCAGGCGACCCACTGCATGA

Upstream 100 bases:

>100_bases
GTTGGTACCCGCGCCAACTGATCGATCCATCGGTCACAAAAAAGCCCCGGCAACGGGGCTTTTTTTATGCCTTGCTCGTT
GCAGATGGGACAATGAAAAC

Downstream 100 bases:

>100_bases
GCGAGGTGTCTTTCACGGCGGTGCGCGGGGTGTTGTTCGACCTGGATGGCACCTTGATCGATAGTGCGCCTGACCTGGGC
TTTGCTGCGGACCAGTTGCG

Product: 3-demethylubiquinone-9 3-methyltransferase

Products: NA

Alternate protein names: 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHB methyltransferase [H]

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MTVSVNADPAELAKFSELAHRWWDPDSEFRPLHQINPLRLDWINQLSPLEGRKVLDVGCGGGILSDSMARKGAEVTGIDL
ASKALRVARLHALEAETPRVQYREISVEELANECPGSFDTVTCMEMLEHVPDPQSVVAACARLVKPGGWVFFSTINRNAK
AFALAIVGAEYLLKMLPQGTHEYAKFIRPSELASACRQAGLDVLHTRGMQYNPVTGRYWLSGDTDVNYLFATRRPTA

Sequences:

>Translated_237_residues
MTVSVNADPAELAKFSELAHRWWDPDSEFRPLHQINPLRLDWINQLSPLEGRKVLDVGCGGGILSDSMARKGAEVTGIDL
ASKALRVARLHALEAETPRVQYREISVEELANECPGSFDTVTCMEMLEHVPDPQSVVAACARLVKPGGWVFFSTINRNAK
AFALAIVGAEYLLKMLPQGTHEYAKFIRPSELASACRQAGLDVLHTRGMQYNPVTGRYWLSGDTDVNYLFATRRPTA
>Mature_236_residues
TVSVNADPAELAKFSELAHRWWDPDSEFRPLHQINPLRLDWINQLSPLEGRKVLDVGCGGGILSDSMARKGAEVTGIDLA
SKALRVARLHALEAETPRVQYREISVEELANECPGSFDTVTCMEMLEHVPDPQSVVAACARLVKPGGWVFFSTINRNAKA
FALAIVGAEYLLKMLPQGTHEYAKFIRPSELASACRQAGLDVLHTRGMQYNPVTGRYWLSGDTDVNYLFATRRPTA

Specific function: Ubiquinone biosynthesis. [C]

COG id: COG2227

COG function: function code H; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiG/COQ3 family [H]

Homologues:

Organism=Homo sapiens, GI118600965, Length=242, Percent_Identity=38.4297520661157, Blast_Score=179, Evalue=3e-45,
Organism=Escherichia coli, GI1788564, Length=233, Percent_Identity=56.2231759656652, Blast_Score=271, Evalue=3e-74,
Organism=Caenorhabditis elegans, GI115533050, Length=237, Percent_Identity=34.1772151898734, Blast_Score=131, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6324476, Length=287, Percent_Identity=33.7979094076655, Blast_Score=129, Evalue=3e-31,
Organism=Drosophila melanogaster, GI281365311, Length=228, Percent_Identity=31.5789473684211, Blast_Score=126, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24585589, Length=190, Percent_Identity=34.2105263157895, Blast_Score=122, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216
- InterPro:   IPR010233 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: =2.1.1.64 [H]

Molecular weight: Translated: 26240; Mature: 26109

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVSVNADPAELAKFSELAHRWWDPDSEFRPLHQINPLRLDWINQLSPLEGRKVLDVGCG
CEEECCCCHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHHCCCCCCCEEEEECCC
GGILSDSMARKGAEVTGIDLASKALRVARLHALEAETPRVQYREISVEELANECPGSFDT
CCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHCCCCCHH
VTCMEMLEHVPDPQSVVAACARLVKPGGWVFFSTINRNAKAFALAIVGAEYLLKMLPQGT
HHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCH
HEYAKFIRPSELASACRQAGLDVLHTRGMQYNPVTGRYWLSGDTDVNYLFATRRPTA
HHHHHHCCHHHHHHHHHHCCCHHHHHCCCEECCCCCEEEECCCCCCEEEEECCCCCC
>Mature Secondary Structure 
TVSVNADPAELAKFSELAHRWWDPDSEFRPLHQINPLRLDWINQLSPLEGRKVLDVGCG
EEECCCCHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHHCCCCCCCEEEEECCC
GGILSDSMARKGAEVTGIDLASKALRVARLHALEAETPRVQYREISVEELANECPGSFDT
CCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHCCCCCHH
VTCMEMLEHVPDPQSVVAACARLVKPGGWVFFSTINRNAKAFALAIVGAEYLLKMLPQGT
HHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCH
HEYAKFIRPSELASACRQAGLDVLHTRGMQYNPVTGRYWLSGDTDVNYLFATRRPTA
HHHHHHCCHHHHHHHHHHCCCHHHHHCCCEECCCCCEEEECCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA