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The map label for this gene is pncB

Identifier: 222110568

GI number: 222110568

Start: 1429792

End: 1430988

Strand: Direct

Name: pncB

Synonym: Dtpsy_1368

Alternate gene names: 222110568

Gene position: 1429792-1430988 (Clockwise)

Preceding gene: 222110567

Following gene: 222110569

Centisome position: 37.66

GC content: 64.83

Gene sequence:

>1197_bases
ATGATCATCACCAGCCTGCTCGACACCGACCTGTACAAGTTCACCATGATGCAGGTGGTGCTGCACCAGTTTCCGGGCGC
GCAGGTGGAGTACCGCTTCAAGTGCCGCAACCCGGGTGTGGAGCTGGCGCCCTTCGTCAGCGAGATCCGCGACGAGATCC
GCGCTTTGTGCAGCCTGCAGTTCCAGGACGCGGAGCTGGCCTACCTGCGCTCGCTGCGCTTCATCAAGAGCGACTTCGTC
GACTTCCTGGGGCTGTTTCGCCTCAACGAGAAGTACATCCGCGTGAGCGCGCTGCCCTCGGGCGAGATCGACATCACCAT
CACCGGGCCCTGGCTGCACACCATCCTGTTCGAGATCCCCGTGCTGGCGATCGTGAACGAGGTGTACTTCCGCAACACGC
AGAAGGTGCCCGACTTTCCCGAGGGGCGCCGCCGGCTCGAAGCCAAGATCGGCCAGCTGCAGCAGCCGGGGTTGGACAGT
CTCAAGATTGCCGACTACGGCACGCGCCGGCGCTTTTCGCGCGCCTGGCACGAGGAGGTGCTGCGCGTGCTGTGCGTGCG
CCTGGGCTCTGACGACCGGCGCGGCGCGCCGGGGCAGTTTGCGGGCACGAGCAACGTGTTGTACGCAATGAAGCTGGGCG
TGACGCCGCTGGGCACCATGGCGCACGAATACCTGCAGGCCTGCCAGTCCCTCGGCCCGCGGCTGCGCGACAGCCAGGTG
TTCGGCTTCGAAATGTGGGCCAAGGAATACCGCGGCGACCTGGGGATCGCGCTGTCCGACGTGTACGGCATGAGCGCCTT
CCTGCGCGACTTCGACCTGTACTTCTGCAAGCTGTTCGATGGCGCGCGCCACGACAGCGGCGATCCCTTCGCATGGGGCG
AGCGGCTGCTGCAGCACTACCGCGACAACCGTGTCGACCCGCTGACCAAGACGCTGATCTTCAGCGACGCGCTGACCGTG
CCGCGCATCATCGAGCTGTACCAGCGCTTCAACGGCCGCTGCCAGTTGGCGTTCGGCATCGGCACCAACCTGACCAACGA
CCTGGGCTACGAGCCACTGCAGATCGTGATCAAGATGACGCGCTGCAACGGCCAGCCCGTGGCCAAGCTGTCGGACGCAC
CCGGCAAGAACATGTGCAACGACGAAAAATACCTGGCTTACCTGCGCCAGGTGTTCGAGATTCCCTCGCCGCAGTGA

Upstream 100 bases:

>100_bases
CCAGAATCAGGGGCTCGCCGGCCCGGCCACGCGTGTGTGGCGGCGCGGCGGACCCCCATCGCCATGTCCAGTAGCGGGAC
AGTCTGCCCCGCGCGCATCC

Downstream 100 bases:

>100_bases
GCGCGCGCCTGGCGCCGCCGGCGGCATTTCAACTTTCCCAAGAACGACCCGAGGAGACCTGTCCATGAACCCCATCCGCA
CCCTGGCCCTTGGGCTGCTG

Product: nicotinate phosphoribosyltransferase

Products: NA

Alternate protein names: NAPRTase

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MIITSLLDTDLYKFTMMQVVLHQFPGAQVEYRFKCRNPGVELAPFVSEIRDEIRALCSLQFQDAELAYLRSLRFIKSDFV
DFLGLFRLNEKYIRVSALPSGEIDITITGPWLHTILFEIPVLAIVNEVYFRNTQKVPDFPEGRRRLEAKIGQLQQPGLDS
LKIADYGTRRRFSRAWHEEVLRVLCVRLGSDDRRGAPGQFAGTSNVLYAMKLGVTPLGTMAHEYLQACQSLGPRLRDSQV
FGFEMWAKEYRGDLGIALSDVYGMSAFLRDFDLYFCKLFDGARHDSGDPFAWGERLLQHYRDNRVDPLTKTLIFSDALTV
PRIIELYQRFNGRCQLAFGIGTNLTNDLGYEPLQIVIKMTRCNGQPVAKLSDAPGKNMCNDEKYLAYLRQVFEIPSPQ

Sequences:

>Translated_398_residues
MIITSLLDTDLYKFTMMQVVLHQFPGAQVEYRFKCRNPGVELAPFVSEIRDEIRALCSLQFQDAELAYLRSLRFIKSDFV
DFLGLFRLNEKYIRVSALPSGEIDITITGPWLHTILFEIPVLAIVNEVYFRNTQKVPDFPEGRRRLEAKIGQLQQPGLDS
LKIADYGTRRRFSRAWHEEVLRVLCVRLGSDDRRGAPGQFAGTSNVLYAMKLGVTPLGTMAHEYLQACQSLGPRLRDSQV
FGFEMWAKEYRGDLGIALSDVYGMSAFLRDFDLYFCKLFDGARHDSGDPFAWGERLLQHYRDNRVDPLTKTLIFSDALTV
PRIIELYQRFNGRCQLAFGIGTNLTNDLGYEPLQIVIKMTRCNGQPVAKLSDAPGKNMCNDEKYLAYLRQVFEIPSPQ
>Mature_398_residues
MIITSLLDTDLYKFTMMQVVLHQFPGAQVEYRFKCRNPGVELAPFVSEIRDEIRALCSLQFQDAELAYLRSLRFIKSDFV
DFLGLFRLNEKYIRVSALPSGEIDITITGPWLHTILFEIPVLAIVNEVYFRNTQKVPDFPEGRRRLEAKIGQLQQPGLDS
LKIADYGTRRRFSRAWHEEVLRVLCVRLGSDDRRGAPGQFAGTSNVLYAMKLGVTPLGTMAHEYLQACQSLGPRLRDSQV
FGFEMWAKEYRGDLGIALSDVYGMSAFLRDFDLYFCKLFDGARHDSGDPFAWGERLLQHYRDNRVDPLTKTLIFSDALTV
PRIIELYQRFNGRCQLAFGIGTNLTNDLGYEPLQIVIKMTRCNGQPVAKLSDAPGKNMCNDEKYLAYLRQVFEIPSPQ

Specific function: NAD biosynthesis; nicotinamide to NaMN; second step. [C]

COG id: COG1488

COG function: function code H; Nicotinic acid phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAPRTase family

Homologues:

Organism=Escherichia coli, GI1787162, Length=399, Percent_Identity=42.3558897243108, Blast_Score=324, Evalue=7e-90,
Organism=Saccharomyces cerevisiae, GI6324783, Length=400, Percent_Identity=30.75, Blast_Score=194, Evalue=3e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PNCB_ACIET (B9MHC7)

Other databases:

- EMBL:   CP001392
- RefSeq:   YP_002552832.1
- ProteinModelPortal:   B9MHC7
- SMR:   B9MHC7
- GeneID:   7382620
- GenomeReviews:   CP001392_GR
- KEGG:   dia:Dtpsy_1368
- ProtClustDB:   PRK05321
- GO:   GO:0005737
- HAMAP:   MF_00570
- InterPro:   IPR006406
- InterPro:   IPR015977
- InterPro:   IPR007229
- InterPro:   IPR002638
- PANTHER:   PTHR11098:SF1
- PIRSF:   PIRSF000484
- TIGRFAMs:   TIGR01514

Pfam domain/function: PF04095 NAPRTase; SSF51690 Q_phspho_trans

EC number: =2.4.2.11

Molecular weight: Translated: 45543; Mature: 45543

Theoretical pI: Translated: 7.72; Mature: 7.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIITSLLDTDLYKFTMMQVVLHQFPGAQVEYRFKCRNPGVELAPFVSEIRDEIRALCSLQ
CEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCC
FQDAELAYLRSLRFIKSDFVDFLGLFRLNEKYIRVSALPSGEIDITITGPWLHTILFEIP
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECHHHHHHHHHHH
VLAIVNEVYFRNTQKVPDFPEGRRRLEAKIGQLQQPGLDSLKIADYGTRRRFSRAWHEEV
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHH
LRVLCVRLGSDDRRGAPGQFAGTSNVLYAMKLGVTPLGTMAHEYLQACQSLGPRLRDSQV
HHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCC
FGFEMWAKEYRGDLGIALSDVYGMSAFLRDFDLYFCKLFDGARHDSGDPFAWGERLLQHY
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
RDNRVDPLTKTLIFSDALTVPRIIELYQRFNGRCQLAFGIGTNLTNDLGYEPLQIVIKMT
HCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCHHHHHHHHH
RCNGQPVAKLSDAPGKNMCNDEKYLAYLRQVFEIPSPQ
HCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MIITSLLDTDLYKFTMMQVVLHQFPGAQVEYRFKCRNPGVELAPFVSEIRDEIRALCSLQ
CEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCC
FQDAELAYLRSLRFIKSDFVDFLGLFRLNEKYIRVSALPSGEIDITITGPWLHTILFEIP
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECHHHHHHHHHHH
VLAIVNEVYFRNTQKVPDFPEGRRRLEAKIGQLQQPGLDSLKIADYGTRRRFSRAWHEEV
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHH
LRVLCVRLGSDDRRGAPGQFAGTSNVLYAMKLGVTPLGTMAHEYLQACQSLGPRLRDSQV
HHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCC
FGFEMWAKEYRGDLGIALSDVYGMSAFLRDFDLYFCKLFDGARHDSGDPFAWGERLLQHY
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
RDNRVDPLTKTLIFSDALTVPRIIELYQRFNGRCQLAFGIGTNLTNDLGYEPLQIVIKMT
HCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCHHHHHHHHH
RCNGQPVAKLSDAPGKNMCNDEKYLAYLRQVFEIPSPQ
HCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA