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The map label for this gene is apbE [H]

Identifier: 222110276

GI number: 222110276

Start: 1105507

End: 1106595

Strand: Direct

Name: apbE [H]

Synonym: Dtpsy_1063

Alternate gene names: 222110276

Gene position: 1105507-1106595 (Clockwise)

Preceding gene: 222110275

Following gene: 222110278

Centisome position: 29.12

GC content: 70.16

Gene sequence:

>1089_bases
ATGAATTCAGATCGGTGCATGCCGGCGGTAGGCAACCGGTGGACGCGGCGGCGCTTCGCCCTTGCGCTGCCGTTGCTGGG
CGCGCTGGCGTACCTCCACCCGCGCCAGGCTTTGGCTGGCATGGTGGAGGGCGCGCAGCCCCTGGTGCGCGCGAGCCGTA
CCCTCATGGGCACACGCGTGGACATCGCGGCTGCCGTTGGCAATGGCCGCGATGCCGGCGCTGTGCAGCAGGCGATGCTG
CACGCATTCGCGGAAATGGAGCGCCTGGAGGCGCTCATGAGCCGTTACCGGGAGGGCAGCGACGTGGCGCGGCTCGGCGC
GGCCGCCGGCCGGCATGCCGTGCACGTGGCCCCGGAAGTGATGCAGGTGCTGCGCACGGCGCGTCGCCTGCACCAAGAAA
GTGCTGGCGCCTTTGATCCCACCGTCGGTGCACTGCGGGGCTGGCATTTTGAGCCCGGCCACGAAGCCGCGCCGGCACCT
GAGGAGATCGCTCAGGCGCTGCGTTTGGTGAACGCGCGCCACCTCGTGCTGGACGAGCGCGCAGGAACGGCCTACCTTGC
GCGGCCGGGCATGGGGTTGGATCTGGGCGGCGTGGCGAAGCTACCTATTTTGCAGGCGGGCTTGCAAGTGCTGGAGCGCG
CTGGCGTCACGGATGCGCTGGCCAACGGCGGTGGCGATGTCCTGGTCATGGGCCGGCAGCACGACCGTCCCTGGCGTGTG
GGCGTGCGCAATCCCTCCGCTCCGGCGCAGCTGCTGGGCGTACTGGAACTGCAAGGGCGCGGCGTGGTGGCATCGTCCGG
CGACTACGAGCGGGGCTTCCTGCGTGCAGGACGCCGCCTGCACCATGTGCTCAACCCCCGCACGGGTTGGCCTACGGAAG
GTGTGTCTGGCGTGGCGCTCATGGCCGAGCGTGTTGAAGACGTCAACGGCTGGGGCACGGCGCTGATGGTGCAAGGGGCT
GCGGCCGCACCTGCATGGCATGCGGACCACGCACATGTCGAAGCCCTCGTGGCGAGCGCTGATGGCACGCCCTGGAGTTC
CCCTGGAATGCTCGCCGCGCTGCGGCCAGTGCCGGCGCGCGCAGGATGA

Upstream 100 bases:

>100_bases
GCCCGCGCGCGGCGGCGCGGCTTCGCTGAGCGACGATGAAGTGAAGGCCGCCGTGGATTTCATGGCTGACCAGTCGATGT
AAGGACCGGAGGGGCTCGCG

Downstream 100 bases:

>100_bases
AAACGCTTTCTTCGCGGGCCAGCGGCGCCGCGAAGAAAGCTTTTGGCGATTTGCGGCTCAACTGACGGAACAGCAAGCGC
TCCAAGCTATATTGTTGATA

Product: apbe family lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MNSDRCMPAVGNRWTRRRFALALPLLGALAYLHPRQALAGMVEGAQPLVRASRTLMGTRVDIAAAVGNGRDAGAVQQAML
HAFAEMERLEALMSRYREGSDVARLGAAAGRHAVHVAPEVMQVLRTARRLHQESAGAFDPTVGALRGWHFEPGHEAAPAP
EEIAQALRLVNARHLVLDERAGTAYLARPGMGLDLGGVAKLPILQAGLQVLERAGVTDALANGGGDVLVMGRQHDRPWRV
GVRNPSAPAQLLGVLELQGRGVVASSGDYERGFLRAGRRLHHVLNPRTGWPTEGVSGVALMAERVEDVNGWGTALMVQGA
AAAPAWHADHAHVEALVASADGTPWSSPGMLAALRPVPARAG

Sequences:

>Translated_362_residues
MNSDRCMPAVGNRWTRRRFALALPLLGALAYLHPRQALAGMVEGAQPLVRASRTLMGTRVDIAAAVGNGRDAGAVQQAML
HAFAEMERLEALMSRYREGSDVARLGAAAGRHAVHVAPEVMQVLRTARRLHQESAGAFDPTVGALRGWHFEPGHEAAPAP
EEIAQALRLVNARHLVLDERAGTAYLARPGMGLDLGGVAKLPILQAGLQVLERAGVTDALANGGGDVLVMGRQHDRPWRV
GVRNPSAPAQLLGVLELQGRGVVASSGDYERGFLRAGRRLHHVLNPRTGWPTEGVSGVALMAERVEDVNGWGTALMVQGA
AAAPAWHADHAHVEALVASADGTPWSSPGMLAALRPVPARAG
>Mature_362_residues
MNSDRCMPAVGNRWTRRRFALALPLLGALAYLHPRQALAGMVEGAQPLVRASRTLMGTRVDIAAAVGNGRDAGAVQQAML
HAFAEMERLEALMSRYREGSDVARLGAAAGRHAVHVAPEVMQVLRTARRLHQESAGAFDPTVGALRGWHFEPGHEAAPAP
EEIAQALRLVNARHLVLDERAGTAYLARPGMGLDLGGVAKLPILQAGLQVLERAGVTDALANGGGDVLVMGRQHDRPWRV
GVRNPSAPAQLLGVLELQGRGVVASSGDYERGFLRAGRRLHHVLNPRTGWPTEGVSGVALMAERVEDVNGWGTALMVQGA
AAAPAWHADHAHVEALVASADGTPWSSPGMLAALRPVPARAG

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

Organism=Escherichia coli, GI1788543, Length=248, Percent_Identity=26.2096774193548, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 38310; Mature: 38310

Theoretical pI: Translated: 10.34; Mature: 10.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSDRCMPAVGNRWTRRRFALALPLLGALAYLHPRQALAGMVEGAQPLVRASRTLMGTRV
CCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCHHHHHHHHHHHHCCHH
DIAAAVGNGRDAGAVQQAMLHAFAEMERLEALMSRYREGSDVARLGAAAGRHAVHVAPEV
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEECHHH
MQVLRTARRLHQESAGAFDPTVGALRGWHFEPGHEAAPAPEEIAQALRLVNARHLVLDER
HHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEECC
AGTAYLARPGMGLDLGGVAKLPILQAGLQVLERAGVTDALANGGGDVLVMGRQHDRPWRV
CCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCCEEEECCCCCCCEEE
GVRNPSAPAQLLGVLELQGRGVVASSGDYERGFLRAGRRLHHVLNPRTGWPTEGVSGVAL
CCCCCCCHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
MAERVEDVNGWGTALMVQGAAAAPAWHADHAHVEALVASADGTPWSSPGMLAALRPVPAR
HHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCEEEECCCCCC
AG
CC
>Mature Secondary Structure
MNSDRCMPAVGNRWTRRRFALALPLLGALAYLHPRQALAGMVEGAQPLVRASRTLMGTRV
CCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCHHHHHHHHHHHHCCHH
DIAAAVGNGRDAGAVQQAMLHAFAEMERLEALMSRYREGSDVARLGAAAGRHAVHVAPEV
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEECHHH
MQVLRTARRLHQESAGAFDPTVGALRGWHFEPGHEAAPAPEEIAQALRLVNARHLVLDER
HHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEECC
AGTAYLARPGMGLDLGGVAKLPILQAGLQVLERAGVTDALANGGGDVLVMGRQHDRPWRV
CCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCCEEEECCCCCCCEEE
GVRNPSAPAQLLGVLELQGRGVVASSGDYERGFLRAGRRLHHVLNPRTGWPTEGVSGVAL
CCCCCCCHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
MAERVEDVNGWGTALMVQGAAAAPAWHADHAHVEALVASADGTPWSSPGMLAALRPVPAR
HHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCEEEECCCCCC
AG
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]