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The map label for this gene is ccmA [H]

Identifier: 222110104

GI number: 222110104

Start: 914138

End: 914794

Strand: Direct

Name: ccmA [H]

Synonym: Dtpsy_0890

Alternate gene names: 222110104

Gene position: 914138-914794 (Clockwise)

Preceding gene: 222110101

Following gene: 222110105

Centisome position: 24.08

GC content: 69.25

Gene sequence:

>657_bases
ATGCTGAAGTGCCCCGAGCCTATTGCATCCCCGCCCGCGTTGCGGGCCGACGGGATCTGCTTCGGCTTTGCGCAACGGCC
CTTGTTCCAGCATTGGAGCGCGGATTTTCCCGCAGGCCTGGTGCTGGTGCAGGGTGGGGACGGGGCGGGCAAGACCAGCC
TGTTGCGCCTGATGGCCGGAGAGTGGGCGCCGCAGGCCGGGCGGATGCTGCTGCATGGCACGAGCGCGACGCAGAATCCT
GCGCAATACCGGGCACAGGTCTTTTGGCGCGACCCGCGCGCGCCGTGGCCGCAGGCGATGACGGCGCGGGACTGGGCCGC
CGGGCTGCGCACGGTCCATGCGCGCTGGTCCGAGGAGGACTGGCACGCCCACGTCGTGGGCTGGGGCATTGCCGGGCATT
TGCACAAGGCCATGCACCAGCTTTCCGCAGGCAGCCAGCGCAAGGTGCTGATGGCCGGTGAACTGGCCAGCGGCGCCCCA
CTGACATTGCTGGATGAGCCGCTGGCCGGCCTGGACAAGGCGTCCATTGCCTACCTGCTGCAGGCGCTGCAGCGGGAGGC
AAGTGCACCCCGCACCGCTGGGCGCGTGTTGGTGGTGGCGCATTACGATGCGTTGGGCGATCTGCCCTGGCGCCACCGGG
TGGTACTGCCGGAATAA

Upstream 100 bases:

>100_bases
CCGTGCCTTCCTCATCCTCGCTGTAGTCAAAATCCAGAAAATGCAAAGTCATGCGACAACCCAGCCCTGTGATGCGGGCG
CTGTTTCTTCAGGAGAAATC

Downstream 100 bases:

>100_bases
ACTGGCGCACCTTTTTCCGCGCCTGCTGGCGCAAGGAGTTGTCGTGGAAGCCCTGCTGTTTGCCCCCGCCGCCGTTGCCA
TTGCGCTCACGCCCGGCCCC

Product: ABC transporter

Products: NA

Alternate protein names: Heme exporter protein A [H]

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MLKCPEPIASPPALRADGICFGFAQRPLFQHWSADFPAGLVLVQGGDGAGKTSLLRLMAGEWAPQAGRMLLHGTSATQNP
AQYRAQVFWRDPRAPWPQAMTARDWAAGLRTVHARWSEEDWHAHVVGWGIAGHLHKAMHQLSAGSQRKVLMAGELASGAP
LTLLDEPLAGLDKASIAYLLQALQREASAPRTAGRVLVVAHYDALGDLPWRHRVVLPE

Sequences:

>Translated_218_residues
MLKCPEPIASPPALRADGICFGFAQRPLFQHWSADFPAGLVLVQGGDGAGKTSLLRLMAGEWAPQAGRMLLHGTSATQNP
AQYRAQVFWRDPRAPWPQAMTARDWAAGLRTVHARWSEEDWHAHVVGWGIAGHLHKAMHQLSAGSQRKVLMAGELASGAP
LTLLDEPLAGLDKASIAYLLQALQREASAPRTAGRVLVVAHYDALGDLPWRHRVVLPE
>Mature_218_residues
MLKCPEPIASPPALRADGICFGFAQRPLFQHWSADFPAGLVLVQGGDGAGKTSLLRLMAGEWAPQAGRMLLHGTSATQNP
AQYRAQVFWRDPRAPWPQAMTARDWAAGLRTVHARWSEEDWHAHVVGWGIAGHLHKAMHQLSAGSQRKVLMAGELASGAP
LTLLDEPLAGLDKASIAYLLQALQREASAPRTAGRVLVVAHYDALGDLPWRHRVVLPE

Specific function: Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system [H]

COG id: COG1131

COG function: function code V; ABC-type multidrug transport system, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI87081791, Length=136, Percent_Identity=31.6176470588235, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR005895
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: =3.6.3.41 [H]

Molecular weight: Translated: 23718; Mature: 23718

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKCPEPIASPPALRADGICFGFAQRPLFQHWSADFPAGLVLVQGGDGAGKTSLLRLMAG
CCCCCCCCCCCCCCCCCCEEEECHHCHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHC
EWAPQAGRMLLHGTSATQNPAQYRAQVFWRDPRAPWPQAMTARDWAAGLRTVHARWSEED
CCCCCCCCEEEECCCCCCCHHHHEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
WHAHVVGWGIAGHLHKAMHQLSAGSQRKVLMAGELASGAPLTLLDEPLAGLDKASIAYLL
CEEEEEEECHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEECCCCCCCCHHHHHHHH
QALQREASAPRTAGRVLVVAHYDALGDLPWRHRVVLPE
HHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCEEECCC
>Mature Secondary Structure
MLKCPEPIASPPALRADGICFGFAQRPLFQHWSADFPAGLVLVQGGDGAGKTSLLRLMAG
CCCCCCCCCCCCCCCCCCEEEECHHCHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHC
EWAPQAGRMLLHGTSATQNPAQYRAQVFWRDPRAPWPQAMTARDWAAGLRTVHARWSEED
CCCCCCCCEEEECCCCCCCHHHHEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
WHAHVVGWGIAGHLHKAMHQLSAGSQRKVLMAGELASGAPLTLLDEPLAGLDKASIAYLL
CEEEEEEECHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEECCCCCCCCHHHHHHHH
QALQREASAPRTAGRVLVVAHYDALGDLPWRHRVVLPE
HHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA