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The map label for this gene is hipO [H]

Identifier: 222109881

GI number: 222109881

Start: 689418

End: 690644

Strand: Direct

Name: hipO [H]

Synonym: Dtpsy_0665

Alternate gene names: 222109881

Gene position: 689418-690644 (Clockwise)

Preceding gene: 222109880

Following gene: 222109882

Centisome position: 18.16

GC content: 68.79

Gene sequence:

>1227_bases
ATGCAGGCCGTGCAGCAGCGCTTGAAGGCAGGCGGACGCGCTTTCGCCCACATCGCGCAGTACCACCCGGAGCTCACCGC
ATTCCGCCGCGACCTGCATGCCCACCCCGAGCTGGGCTTTGAAGAGGTCTACACCAGCGCCCGTGTGCGCGAGGCGCTGC
GGCACGCCGGCGTGGACGAGGTGCACGAAGGCATCGGCCGTACCGGCGTGGTGGGCATCATCCACGGCCAGGGACGCAGC
AGCGGCAGCATGATCGGTCTGCGGGCCGACATGGACGCGCTGCCCATGGCCGAGCACAACGATTTCGCCTGGAAGTCCTG
CAAGAGCGGCCTGATGCATGGCTGCGGCCATGATGGGCACACGGCCATGCTCGTGGGTGCAGCACGCTACCTGGCGACCA
CGCGCCATTTCGACGGTACGGCGGTGCTGATCTTCCAGCCCGGCGAGGAAGGCCTGGGCGGTGCGCGCGTGATGATCGAG
GACGGGCTCTTCGAGCGCTTTCCCGTGCAGTCGGTGTACGCCATGCACAACTGGCCGGCCATGCGGCCCGGCACCGTGGG
TATCAACAGCGGCGCCATGATGGCGGCGGCCGACCGCGTCACGATCGAAGTGACCGGGCGCGGCGGCCACGGTGCGCATG
CGTACCAGACGGTGGACGTGGTGCTAGTGGCCGCGCACATCGTCACCGCCGTGCAGGGGATCGTCTCGCGCAACGTGCGA
CCGCTGGAGAGCGCAGTCATCAGTCTGTGCGCGGTGCAGGCGGGCGACCTGGGTGCGTTCAGCGTGCTGCCGGGCACGGC
CACGCTGGTGGGTACGGTGCGCACGTTCGACCCCGCCGTGCAGGAGATGGTGGAGCGCCGCATCAAGGAGCTGTGCAACG
CCATCGCCCTGGGCTTTGGCGCTACCGCCACCGTTCGCTACGAGCGCATCTACCCTGCCACCATCAACACCGAGAGCGAT
GCGCGCTTCGCAGGCGACGTGGCTGCGTCGCTGGTGGGCGAAGAAAACGTGGACCGCGACCTGGAGCCGAGCATGGGCGC
GGAGGATTTCTCCTTCATGCTGCAGGCCCGGCCCGGCGCCTACCTGCGCCTGGGGCAGGGCATGGGCGCTGGCAACAGCA
CCTTGCACAACAGCCGCTACGACTTCAATGACGACGTGCTGCCCCTGGGCGCGGCCCTGCATGCCGGCCTGGTCGAGCAG
GCCATGCCCCTGGGGCAAGCGCAGTGA

Upstream 100 bases:

>100_bases
ATCGCGCTGATCTTCGTGGTCATCAACCTGGTGGTGGACCTGCTGTACTTCGCAGTGGACCCGCGCCTGCGCGTGGGCGG
CAAGGCGGGAGGGCACTGAC

Downstream 100 bases:

>100_bases
GATCGCACGGTACAGCAGCATGATGCGGAGCACGGTCTGGATGCGAAATATGGCCCTGGCGCTTGTACTGCAAGCGCTAG
CAGCTATATTTTTGGTAGCT

Product: amidohydrolase

Products: NA

Alternate protein names: Benzoylglycine amidohydrolase; Hippuricase [H]

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MQAVQQRLKAGGRAFAHIAQYHPELTAFRRDLHAHPELGFEEVYTSARVREALRHAGVDEVHEGIGRTGVVGIIHGQGRS
SGSMIGLRADMDALPMAEHNDFAWKSCKSGLMHGCGHDGHTAMLVGAARYLATTRHFDGTAVLIFQPGEEGLGGARVMIE
DGLFERFPVQSVYAMHNWPAMRPGTVGINSGAMMAAADRVTIEVTGRGGHGAHAYQTVDVVLVAAHIVTAVQGIVSRNVR
PLESAVISLCAVQAGDLGAFSVLPGTATLVGTVRTFDPAVQEMVERRIKELCNAIALGFGATATVRYERIYPATINTESD
ARFAGDVAASLVGEENVDRDLEPSMGAEDFSFMLQARPGAYLRLGQGMGAGNSTLHNSRYDFNDDVLPLGAALHAGLVEQ
AMPLGQAQ

Sequences:

>Translated_408_residues
MQAVQQRLKAGGRAFAHIAQYHPELTAFRRDLHAHPELGFEEVYTSARVREALRHAGVDEVHEGIGRTGVVGIIHGQGRS
SGSMIGLRADMDALPMAEHNDFAWKSCKSGLMHGCGHDGHTAMLVGAARYLATTRHFDGTAVLIFQPGEEGLGGARVMIE
DGLFERFPVQSVYAMHNWPAMRPGTVGINSGAMMAAADRVTIEVTGRGGHGAHAYQTVDVVLVAAHIVTAVQGIVSRNVR
PLESAVISLCAVQAGDLGAFSVLPGTATLVGTVRTFDPAVQEMVERRIKELCNAIALGFGATATVRYERIYPATINTESD
ARFAGDVAASLVGEENVDRDLEPSMGAEDFSFMLQARPGAYLRLGQGMGAGNSTLHNSRYDFNDDVLPLGAALHAGLVEQ
AMPLGQAQ
>Mature_408_residues
MQAVQQRLKAGGRAFAHIAQYHPELTAFRRDLHAHPELGFEEVYTSARVREALRHAGVDEVHEGIGRTGVVGIIHGQGRS
SGSMIGLRADMDALPMAEHNDFAWKSCKSGLMHGCGHDGHTAMLVGAARYLATTRHFDGTAVLIFQPGEEGLGGARVMIE
DGLFERFPVQSVYAMHNWPAMRPGTVGINSGAMMAAADRVTIEVTGRGGHGAHAYQTVDVVLVAAHIVTAVQGIVSRNVR
PLESAVISLCAVQAGDLGAFSVLPGTATLVGTVRTFDPAVQEMVERRIKELCNAIALGFGATATVRYERIYPATINTESD
ARFAGDVAASLVGEENVDRDLEPSMGAEDFSFMLQARPGAYLRLGQGMGAGNSTLHNSRYDFNDDVLPLGAALHAGLVEQ
AMPLGQAQ

Specific function: Required But Not Essential For Aminobenzoyl-Glutamate Utilization. May Participate In Hydrolysis Of Aminobenzoyl- Glutamate To Aminobenzoate, Either Alone Or In Combination With Abgb. [C]

COG id: COG1473

COG function: function code R; Metal-dependent amidase/aminoacylase/carboxypeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20 family [H]

Homologues:

Organism=Escherichia coli, GI87081880, Length=423, Percent_Identity=27.6595744680851, Blast_Score=92, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017439
- InterPro:   IPR010168
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.32 [H]

Molecular weight: Translated: 43477; Mature: 43477

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAVQQRLKAGGRAFAHIAQYHPELTAFRRDLHAHPELGFEEVYTSARVREALRHAGVDE
CHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHH
VHEGIGRTGVVGIIHGQGRSSGSMIGLRADMDALPMAEHNDFAWKSCKSGLMHGCGHDGH
HHHCCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCC
TAMLVGAARYLATTRHFDGTAVLIFQPGEEGLGGARVMIEDGLFERFPVQSVYAMHNWPA
HHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEEECCCHHHCCHHHHHHHHCCCC
MRPGTVGINSGAMMAAADRVTIEVTGRGGHGAHAYQTVDVVLVAAHIVTAVQGIVSRNVR
CCCCCEECCCCCEEEECCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PLESAVISLCAVQAGDLGAFSVLPGTATLVGTVRTFDPAVQEMVERRIKELCNAIALGFG
HHHHHHHHHHHHCCCCCCCEEECCCCEEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHCCC
ATATVRYERIYPATINTESDARFAGDVAASLVGEENVDRDLEPSMGAEDFSFMLQARPGA
CEEEEEEEEEECEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHEECCCCC
YLRLGQGMGAGNSTLHNSRYDFNDDVLPLGAALHAGLVEQAMPLGQAQ
EEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQAVQQRLKAGGRAFAHIAQYHPELTAFRRDLHAHPELGFEEVYTSARVREALRHAGVDE
CHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHH
VHEGIGRTGVVGIIHGQGRSSGSMIGLRADMDALPMAEHNDFAWKSCKSGLMHGCGHDGH
HHHCCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCC
TAMLVGAARYLATTRHFDGTAVLIFQPGEEGLGGARVMIEDGLFERFPVQSVYAMHNWPA
HHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEEECCCHHHCCHHHHHHHHCCCC
MRPGTVGINSGAMMAAADRVTIEVTGRGGHGAHAYQTVDVVLVAAHIVTAVQGIVSRNVR
CCCCCEECCCCCEEEECCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PLESAVISLCAVQAGDLGAFSVLPGTATLVGTVRTFDPAVQEMVERRIKELCNAIALGFG
HHHHHHHHHHHHCCCCCCCEEECCCCEEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHCCC
ATATVRYERIYPATINTESDARFAGDVAASLVGEENVDRDLEPSMGAEDFSFMLQARPGA
CEEEEEEEEEECEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHEECCCCC
YLRLGQGMGAGNSTLHNSRYDFNDDVLPLGAALHAGLVEQAMPLGQAQ
EEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7730270; 10688204 [H]