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The map label for this gene is qseD [H]

Identifier: 222109802

GI number: 222109802

Start: 606304

End: 607251

Strand: Direct

Name: qseD [H]

Synonym: Dtpsy_0586

Alternate gene names: 222109802

Gene position: 606304-607251 (Clockwise)

Preceding gene: 222109798

Following gene: 222109803

Centisome position: 15.97

GC content: 67.51

Gene sequence:

>948_bases
ATGCGGGCCATGGAAACCAAATGGCTCGAAGACTTCGTCAGCCTGGCAGAAACGCGCAGCTTCAGCCGCTCGGCGCAATT
GCGCCATGTGACACAGCCCGCTTTTTCGCGGCGCATCCAGGCGCTGGAGGCCTGGGCCGGCACCGATCTGGTGGACCGCA
GTTCCTACCCCACGCGGCTGACGGCCGCGGGCAACACGCTGTACGACCAGGCGCTGGAGGTGCTGCAGGCGCTGCAGAAC
ACGCGCGCCATGCTGCGCGCGCACACCAGCGCGGGCACCGACATGATCGAGTTCGCCGTGCCGCATACGCTGGCGTTCAC
TTTTTTCCCGGCCTGGGTGTCGGCGCTGCGGGCGGACTTCGGCCCGCTCAAAAGCCGACTGATCGCCCTGAACGTGCACG
ACGCGGTGATGCGCCTCGTGGAGGGCGGCTGCGATCTGCTCATCTCCTACCACCATCCATCGCAGCCCCTGCAACTGGAC
CCGGACCGCTACGAGATGGTGACGCTGGGGCAGGAGGTCCTGGCCCCCTACGCCAAGGCGGGCGCGGATGGTCAGCCGCT
GTTTTGCCTGCCGGGCCGGCCTGGCGAGCCGCTGCCCTACCTGGGGTATGCGCCAGGGGCCTACTTGGGGCGCGTGACGG
AGCTGATCCTCAAGCAGGCGGGGACGGCCATCCACTTGGACCGCGTGTACGAAACGGATATGGCCGAAGGCCTGAAGGCC
ATGGCGCTGGAAGGACACGGCGTCGCCTTCTTGCCCTATAGCGCGGTGAAGAAGGAACTGCGTTCGCGCAAGCTCCTGAG
CGCGGCGCCGCCCGACGCGCAGGACCTGCAGATGGTGATGGAAGTGCGCGCCTACCGCGAAAAGCCCTCGCGCAAGGAGC
CGGCCAAGGGCCTGGCCCAGTCCCTGTGGACGTACCTGCAGACGCGCGCCGGACAGAACCCCATCTGA

Upstream 100 bases:

>100_bases
CAAACGTACGGTGCTCCGCCGCAGGGTGTTCCCCAGGAGGGTGCTGGGGCGGCCCAGTCGCGCTCAACAGGGGGAGAAGG
CCTGCCTGGGCGCATCGATA

Downstream 100 bases:

>100_bases
CGCGAGCGCACCACACTTGGCATGCGAGTCTTGCATGCAAACCCACATCCCTGGCATTGGATTGCGTGGTCACGCGACAT
TACAGTCTTTGAAACTAAAT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Quorum-sensing regulator protein D [H]

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MRAMETKWLEDFVSLAETRSFSRSAQLRHVTQPAFSRRIQALEAWAGTDLVDRSSYPTRLTAAGNTLYDQALEVLQALQN
TRAMLRAHTSAGTDMIEFAVPHTLAFTFFPAWVSALRADFGPLKSRLIALNVHDAVMRLVEGGCDLLISYHHPSQPLQLD
PDRYEMVTLGQEVLAPYAKAGADGQPLFCLPGRPGEPLPYLGYAPGAYLGRVTELILKQAGTAIHLDRVYETDMAEGLKA
MALEGHGVAFLPYSAVKKELRSRKLLSAAPPDAQDLQMVMEVRAYREKPSRKEPAKGLAQSLWTYLQTRAGQNPI

Sequences:

>Translated_315_residues
MRAMETKWLEDFVSLAETRSFSRSAQLRHVTQPAFSRRIQALEAWAGTDLVDRSSYPTRLTAAGNTLYDQALEVLQALQN
TRAMLRAHTSAGTDMIEFAVPHTLAFTFFPAWVSALRADFGPLKSRLIALNVHDAVMRLVEGGCDLLISYHHPSQPLQLD
PDRYEMVTLGQEVLAPYAKAGADGQPLFCLPGRPGEPLPYLGYAPGAYLGRVTELILKQAGTAIHLDRVYETDMAEGLKA
MALEGHGVAFLPYSAVKKELRSRKLLSAAPPDAQDLQMVMEVRAYREKPSRKEPAKGLAQSLWTYLQTRAGQNPI
>Mature_315_residues
MRAMETKWLEDFVSLAETRSFSRSAQLRHVTQPAFSRRIQALEAWAGTDLVDRSSYPTRLTAAGNTLYDQALEVLQALQN
TRAMLRAHTSAGTDMIEFAVPHTLAFTFFPAWVSALRADFGPLKSRLIALNVHDAVMRLVEGGCDLLISYHHPSQPLQLD
PDRYEMVTLGQEVLAPYAKAGADGQPLFCLPGRPGEPLPYLGYAPGAYLGRVTELILKQAGTAIHLDRVYETDMAEGLKA
MALEGHGVAFLPYSAVKKELRSRKLLSAAPPDAQDLQMVMEVRAYREKPSRKEPAKGLAQSLWTYLQTRAGQNPI

Specific function: Down-regulates expression of the flagellar regulon, decreasing motility [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790783, Length=308, Percent_Identity=32.7922077922078, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI145693105, Length=147, Percent_Identity=25.8503401360544, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34879; Mature: 34879

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAMETKWLEDFVSLAETRSFSRSAQLRHVTQPAFSRRIQALEAWAGTDLVDRSSYPTRL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEE
TAAGNTLYDQALEVLQALQNTRAMLRAHTSAGTDMIEFAVPHTLAFTFFPAWVSALRADF
EECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GPLKSRLIALNVHDAVMRLVEGGCDLLISYHHPSQPLQLDPDRYEMVTLGQEVLAPYAKA
HHHHHHEEEECHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHC
GADGQPLFCLPGRPGEPLPYLGYAPGAYLGRVTELILKQAGTAIHLDRVYETDMAEGLKA
CCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHH
MALEGHGVAFLPYSAVKKELRSRKLLSAAPPDAQDLQMVMEVRAYREKPSRKEPAKGLAQ
HEECCCCEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHH
SLWTYLQTRAGQNPI
HHHHHHHHHCCCCCC
>Mature Secondary Structure
MRAMETKWLEDFVSLAETRSFSRSAQLRHVTQPAFSRRIQALEAWAGTDLVDRSSYPTRL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEE
TAAGNTLYDQALEVLQALQNTRAMLRAHTSAGTDMIEFAVPHTLAFTFFPAWVSALRADF
EECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GPLKSRLIALNVHDAVMRLVEGGCDLLISYHHPSQPLQLDPDRYEMVTLGQEVLAPYAKA
HHHHHHEEEECHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHC
GADGQPLFCLPGRPGEPLPYLGYAPGAYLGRVTELILKQAGTAIHLDRVYETDMAEGLKA
CCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHH
MALEGHGVAFLPYSAVKKELRSRKLLSAAPPDAQDLQMVMEVRAYREKPSRKEPAKGLAQ
HEECCCCEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHH
SLWTYLQTRAGQNPI
HHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 7876157 [H]