Click here to switch to the map view.

The map label for this gene is coaX

Identifier: 222109766

GI number: 222109766

Start: 568834

End: 569610

Strand: Direct

Name: coaX

Synonym: Dtpsy_0550

Alternate gene names: 222109766

Gene position: 568834-569610 (Clockwise)

Preceding gene: 222109764

Following gene: 222109769

Centisome position: 14.98

GC content: 70.4

Gene sequence:

>777_bases
ATGACTTTCCTGGCCATCGACGTGGGCAACACCCGTCTCAAGTGGGCGTTGTTCGACGCAGCGCAGCCCGGTGCCGGCCT
GCTGGCCCATGGCGCTGAATTCCTGGACCATATCGAACGCCTGGCCGAGGGCCCGTGGTCCCACCTGCCTGCGCCCCGGC
ATATGCTGGGTTGCGTGGTGGCGGGCGACGCGGTCAAGCGCCGCGTGGCCGAGCAGATGGAGCTGTGGGACGTGCCCGCG
CGCTGGGTGGTGCCGTCCGCGCAGGAAGCCGGCGTCATCAACGGCTACGACCATCCCACCCGCCTGGGCGCGGACCGCTG
GGTGGCCATGATCGGTGCGCGCCACCGCCTGCTGGCCCAGGGGCCCGCGCGGCCGCTGATCGTGGTGATGGTGGGCACCG
CCGTGACGGTGGAGGCCCTGGACGCGGAGGGTCGCTTCCTGGGCGGCCTGATCCTGCCCGGCCACGGCATCATGCTGCGC
GCACTGGAGTCAGGCACCGCGGGGCTGCACGTGCCCACAGGCGAGGTGCGCCTGTTCCCATCCAACACCAGCGATGCGCT
GACCAGCGGCGGCACCTATGCCATTGCCGGCGCGGTGGAGCGCATGTACCAGCACCTGCGGCAGCACTGCGGGCAGGAAC
CCGCCTGCATGATGACCGGCGGTGCGGGCTGGAAGATGGCGCCAAGCATGACGCGCCCGTTCGAGTTGGTGGAAAACCTG
ATCTTTGACGGCCTGCTGGAGATCGCGGCGCGCCGGTTTGCCGAGCTGCCGGCCTGA

Upstream 100 bases:

>100_bases
GTCCGGCACCGCCATGTCGGAAAAACGCCCGCGCCGGCGGCAGCGCGTGCATTTGCGGCGCTCTGCGGGAGGCAAAGGCA
AAAAACGGATAATCCGCGCC

Downstream 100 bases:

>100_bases
CACGGCCCGCCAGCGCGGGTGTTAAGCGGCCTGGTCGTAGGCCCCGACCAGCCGCGCCAGGTGCGCACGCTGGGTGGGCT
CCAGGTAGGGCATGAGCAGC

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MTFLAIDVGNTRLKWALFDAAQPGAGLLAHGAEFLDHIERLAEGPWSHLPAPRHMLGCVVAGDAVKRRVAEQMELWDVPA
RWVVPSAQEAGVINGYDHPTRLGADRWVAMIGARHRLLAQGPARPLIVVMVGTAVTVEALDAEGRFLGGLILPGHGIMLR
ALESGTAGLHVPTGEVRLFPSNTSDALTSGGTYAIAGAVERMYQHLRQHCGQEPACMMTGGAGWKMAPSMTRPFELVENL
IFDGLLEIAARRFAELPA

Sequences:

>Translated_258_residues
MTFLAIDVGNTRLKWALFDAAQPGAGLLAHGAEFLDHIERLAEGPWSHLPAPRHMLGCVVAGDAVKRRVAEQMELWDVPA
RWVVPSAQEAGVINGYDHPTRLGADRWVAMIGARHRLLAQGPARPLIVVMVGTAVTVEALDAEGRFLGGLILPGHGIMLR
ALESGTAGLHVPTGEVRLFPSNTSDALTSGGTYAIAGAVERMYQHLRQHCGQEPACMMTGGAGWKMAPSMTRPFELVENL
IFDGLLEIAARRFAELPA
>Mature_257_residues
TFLAIDVGNTRLKWALFDAAQPGAGLLAHGAEFLDHIERLAEGPWSHLPAPRHMLGCVVAGDAVKRRVAEQMELWDVPAR
WVVPSAQEAGVINGYDHPTRLGADRWVAMIGARHRLLAQGPARPLIVVMVGTAVTVEALDAEGRFLGGLILPGHGIMLRA
LESGTAGLHVPTGEVRLFPSNTSDALTSGGTYAIAGAVERMYQHLRQHCGQEPACMMTGGAGWKMAPSMTRPFELVENLI
FDGLLEIAARRFAELPA

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX_ACIET (B9MCN0)

Other databases:

- EMBL:   CP001392
- RefSeq:   YP_002552030.1
- ProteinModelPortal:   B9MCN0
- SMR:   B9MCN0
- GeneID:   7382841
- GenomeReviews:   CP001392_GR
- KEGG:   dia:Dtpsy_0550
- ProtClustDB:   PRK13329
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 27735; Mature: 27604

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: ACT_SITE 105-105 BINDING 96-96 BINDING 133-133 BINDING 183-183

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFLAIDVGNTRLKWALFDAAQPGAGLLAHGAEFLDHIERLAEGPWSHLPAPRHMLGCVV
CEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
AGDAVKRRVAEQMELWDVPARWVVPSAQEAGVINGYDHPTRLGADRWVAMIGARHRLLAQ
HHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHC
GPARPLIVVMVGTAVTVEALDAEGRFLGGLILPGHGIMLRALESGTAGLHVPTGEVRLFP
CCCCCEEEEEECCEEEEEEECCCCCEECEEEECCCCEEEEEECCCCCCEEECCCCEEEEE
SNTSDALTSGGTYAIAGAVERMYQHLRQHCGQEPACMMTGGAGWKMAPSMTRPFELVENL
CCCCHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCHHHHHHHH
IFDGLLEIAARRFAELPA
HHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TFLAIDVGNTRLKWALFDAAQPGAGLLAHGAEFLDHIERLAEGPWSHLPAPRHMLGCVV
EEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
AGDAVKRRVAEQMELWDVPARWVVPSAQEAGVINGYDHPTRLGADRWVAMIGARHRLLAQ
HHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHC
GPARPLIVVMVGTAVTVEALDAEGRFLGGLILPGHGIMLRALESGTAGLHVPTGEVRLFP
CCCCCEEEEEECCEEEEEEECCCCCEECEEEECCCCEEEEEECCCCCCEEECCCCEEEEE
SNTSDALTSGGTYAIAGAVERMYQHLRQHCGQEPACMMTGGAGWKMAPSMTRPFELVENL
CCCCHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCHHHHHHHH
IFDGLLEIAARRFAELPA
HHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA