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The map label for this gene is secY [H]

Identifier: 222109613

GI number: 222109613

Start: 400275

End: 401594

Strand: Direct

Name: secY [H]

Synonym: Dtpsy_0393

Alternate gene names: 222109613

Gene position: 400275-401594 (Clockwise)

Preceding gene: 222109612

Following gene: 222109614

Centisome position: 10.54

GC content: 57.12

Gene sequence:

>1320_bases
GTGGCTACTAACGCAGCTCAACTGGCAAAAACCGGTAAGTTTGGCGATCTCCGCCGGCGTCTGGTCTTTCTGCTGCTCGC
GTTGGTTGTGTACCGCATCGGCGCGCACATTCCCGTTCCTGGGATTGATCCGGCGCAGCTGCAGCAGTTGTTCAGTGGCC
AGCAGGGCGGCATTCTCAACCTCTTCAATATGTTCTCGGGTGGAGCGCTCTCGCGCTTCACGGTCTTCGCGCTGGGGATC
ATGCCGTACATCTCGGCATCGATCATCATGCAGCTGATGACCTATGTGGTGCCCACATTCGAGCAGTTGAAGAAGGAAGG
GGAGGCCGGGCGCCGCAAGATCACGCAGTACACCCGTTATGGAACGTTGGGCTTGGCGATTTTCCAATCGCTGGGTATCG
CGGTGGCTCTGGAGAGCTCCGCAGGTCTCGTGTTGAGTCCGGGCTTCGGCTTCCGGCTCACGGCAGTGGTCAGCCTGACC
GCCGGCACGATGTTCCTGATGTGGCTGGGTGAACAGATCACTGAGCGCGGCCTGGGCAACGGTATTTCGATCCTGATTTT
TGCCGGTATCGCCGCGGGTCTGCCCAGTTCTATCGGTGGTCTGTTGGAGTTGGTGCGCACGGGGGCGATGAGCATCCTGG
CAGCCATCTTCATCGTGATCGTCGTGGGACTGGTGACGTACTTCGTCGTCTTCGTCGAACGTGGTCAGCGCAAGATACTG
GTGAACTATGCGCGGCGCCAGGTGGGCAACAAGGTCTATGGTGGGCAATCCTCCCATCTGCCTTTGAAGCTCAACATGGC
CGGTGTGATTCCTCCAATCTTTGCATCGTCCATCATCCTGCTGCCTGCAACCATTGTGAATTGGTTCAGCGCGGGAGAGT
CGATGCGGTGGTTGCGTGATATTTCTGCGGCACTGACGCCCGGCCAGCCGGTCTATGTGATGTTCTACGCCGCGGCGATC
ATCTTCTTCTGTTTCTTCTACACGGCTCTGGTTTTCAACAGCCGCGAAACGGCAGACAACCTGAAGAAGAGCGGAGCATT
CATTCCAGGCATCCGCCCGGGTGAACATACCGCGCGCTACATCGACAAGATCCTGGTGCGGCTGACGCTGGCCGGGGCTG
TTTACATCACCTTCGTGTGTTTGCTGCCCGAGTTCCTGATCCTGAAGTACAACGTGCCGTTCTATTTTGGTGGTACGTCG
TTGCTGATCATCGTTGTCGTGACGATGGACTTCATGGCTCAGGTACAGAACTACATGATGTCGCAGCAGTACGAGTCGCT
GCTGAAGAAGGCTAACTTCAAGACGACATTAGGTACCTGA

Upstream 100 bases:

>100_bases
CTGTGAAGCTGTCGGGAATCACCGCAACTGCTGGCGCCAAGGCTGCCATCGAAGCGGCCGGCGGTAGCCTGGCCTGATCT
GGTTCTGACGAAAGGCATCT

Downstream 100 bases:

>100_bases
TGTCCGTGTGCCTTTGGCGAATGCGCTATAGTCGCGGGTTCGCCAAGAAGCAACGGCTTATTGATGCCCTTCGATCCATC
GCGGGCACTTACTTTGTGTT

Product: preprotein translocase subunit SecFY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 438

Protein sequence:

>439_residues
MATNAAQLAKTGKFGDLRRRLVFLLLALVVYRIGAHIPVPGIDPAQLQQLFSGQQGGILNLFNMFSGGALSRFTVFALGI
MPYISASIIMQLMTYVVPTFEQLKKEGEAGRRKITQYTRYGTLGLAIFQSLGIAVALESSAGLVLSPGFGFRLTAVVSLT
AGTMFLMWLGEQITERGLGNGISILIFAGIAAGLPSSIGGLLELVRTGAMSILAAIFIVIVVGLVTYFVVFVERGQRKIL
VNYARRQVGNKVYGGQSSHLPLKLNMAGVIPPIFASSIILLPATIVNWFSAGESMRWLRDISAALTPGQPVYVMFYAAAI
IFFCFFYTALVFNSRETADNLKKSGAFIPGIRPGEHTARYIDKILVRLTLAGAVYITFVCLLPEFLILKYNVPFYFGGTS
LLIIVVVTMDFMAQVQNYMMSQQYESLLKKANFKTTLGT

Sequences:

>Translated_439_residues
MATNAAQLAKTGKFGDLRRRLVFLLLALVVYRIGAHIPVPGIDPAQLQQLFSGQQGGILNLFNMFSGGALSRFTVFALGI
MPYISASIIMQLMTYVVPTFEQLKKEGEAGRRKITQYTRYGTLGLAIFQSLGIAVALESSAGLVLSPGFGFRLTAVVSLT
AGTMFLMWLGEQITERGLGNGISILIFAGIAAGLPSSIGGLLELVRTGAMSILAAIFIVIVVGLVTYFVVFVERGQRKIL
VNYARRQVGNKVYGGQSSHLPLKLNMAGVIPPIFASSIILLPATIVNWFSAGESMRWLRDISAALTPGQPVYVMFYAAAI
IFFCFFYTALVFNSRETADNLKKSGAFIPGIRPGEHTARYIDKILVRLTLAGAVYITFVCLLPEFLILKYNVPFYFGGTS
LLIIVVVTMDFMAQVQNYMMSQQYESLLKKANFKTTLGT
>Mature_438_residues
ATNAAQLAKTGKFGDLRRRLVFLLLALVVYRIGAHIPVPGIDPAQLQQLFSGQQGGILNLFNMFSGGALSRFTVFALGIM
PYISASIIMQLMTYVVPTFEQLKKEGEAGRRKITQYTRYGTLGLAIFQSLGIAVALESSAGLVLSPGFGFRLTAVVSLTA
GTMFLMWLGEQITERGLGNGISILIFAGIAAGLPSSIGGLLELVRTGAMSILAAIFIVIVVGLVTYFVVFVERGQRKILV
NYARRQVGNKVYGGQSSHLPLKLNMAGVIPPIFASSIILLPATIVNWFSAGESMRWLRDISAALTPGQPVYVMFYAAAII
FFCFFYTALVFNSRETADNLKKSGAFIPGIRPGEHTARYIDKILVRLTLAGAVYITFVCLLPEFLILKYNVPFYFGGTSL
LIIVVVTMDFMAQVQNYMMSQQYESLLKKANFKTTLGT

Specific function: Involved in protein export. Interacts with secA and secE to allow the translocation of proteins across the plasma membrane, by forming part of a channel [H]

COG id: COG0201

COG function: function code U; Preprotein translocase subunit SecY

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secY/SEC61-alpha family [H]

Homologues:

Organism=Escherichia coli, GI1789696, Length=431, Percent_Identity=67.9814385150812, Blast_Score=548, Evalue=1e-157,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002208
- InterPro:   IPR023201 [H]

Pfam domain/function: PF00344 SecY [H]

EC number: NA

Molecular weight: Translated: 47894; Mature: 47762

Theoretical pI: Translated: 10.29; Mature: 10.29

Prosite motif: PS00755 SECY_1 ; PS00756 SECY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATNAAQLAKTGKFGDLRRRLVFLLLALVVYRIGAHIPVPGIDPAQLQQLFSGQQGGILN
CCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCHHH
LFNMFSGGALSRFTVFALGIMPYISASIIMQLMTYVVPTFEQLKKEGEAGRRKITQYTRY
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GTLGLAIFQSLGIAVALESSAGLVLSPGFGFRLTAVVSLTAGTMFLMWLGEQITERGLGN
HHHHHHHHHHCCEEEEEECCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GISILIFAGIAAGLPSSIGGLLELVRTGAMSILAAIFIVIVVGLVTYFVVFVERGQRKIL
CHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
VNYARRQVGNKVYGGQSSHLPLKLNMAGVIPPIFASSIILLPATIVNWFSAGESMRWLRD
HHHHHHHHCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
ISAALTPGQPVYVMFYAAAIIFFCFFYTALVFNSRETADNLKKSGAFIPGIRPGEHTARY
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCHHHHHH
IDKILVRLTLAGAVYITFVCLLPEFLILKYNVPFYFGGTSLLIIVVVTMDFMAQVQNYMM
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEECCHHHHHHHHHHHHHHHHHHHHHH
SQQYESLLKKANFKTTLGT
HHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
ATNAAQLAKTGKFGDLRRRLVFLLLALVVYRIGAHIPVPGIDPAQLQQLFSGQQGGILN
CCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCHHH
LFNMFSGGALSRFTVFALGIMPYISASIIMQLMTYVVPTFEQLKKEGEAGRRKITQYTRY
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GTLGLAIFQSLGIAVALESSAGLVLSPGFGFRLTAVVSLTAGTMFLMWLGEQITERGLGN
HHHHHHHHHHCCEEEEEECCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GISILIFAGIAAGLPSSIGGLLELVRTGAMSILAAIFIVIVVGLVTYFVVFVERGQRKIL
CHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
VNYARRQVGNKVYGGQSSHLPLKLNMAGVIPPIFASSIILLPATIVNWFSAGESMRWLRD
HHHHHHHHCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
ISAALTPGQPVYVMFYAAAIIFFCFFYTALVFNSRETADNLKKSGAFIPGIRPGEHTARY
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCHHHHHH
IDKILVRLTLAGAVYITFVCLLPEFLILKYNVPFYFGGTSLLIIVVVTMDFMAQVQNYMM
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEECCHHHHHHHHHHHHHHHHHHHHHH
SQQYESLLKKANFKTTLGT
HHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9322765; 10952301 [H]