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The map label for this gene is trpD

Identifier: 222109579

GI number: 222109579

Start: 368952

End: 369986

Strand: Direct

Name: trpD

Synonym: Dtpsy_0359

Alternate gene names: 222109579

Gene position: 368952-369986 (Clockwise)

Preceding gene: 222109578

Following gene: 222109580

Centisome position: 9.72

GC content: 67.83

Gene sequence:

>1035_bases
ATGACCCCCATCACCCCCCAGGAAGCGCTGCAGCGCACCATCGAGCACCGCGAGATCTTCCACGACGAGATGCTGCACCT
CATGCGCATGATCATGAGCGGCGAACTCTCGCCCGTCATGACCGCGGCCATCACCACCGGCCTGCGCGTGAAGAAGGAAA
CCATCGGCGAGATCACCGCCGCCGCGCAGGTGATGCGCGAGTTCTCCCACAAGGTGCAGGTGCACGACACCAAGCACCTC
GTGGACATCGTGGGCACGGGCGGCGACGGCGCCAACACCTTCAACATCTCCACCTGCGCCACCTTCGTGATCGCCGCCGC
GGGCGCCAAGGTCAGCAAGCATGGCGGGCGCAGCGTCAGCAGCAAAAGCGGCAGCGCCGACGCCATGGAGGCGCTGGGCG
TGCACATCAACCTGCAGCCTGCGCAGATCGCGCAGTGCATTGGCGACGTGGGCATCGGCTTCATGTTCGCGCCCAACCAC
CACCCCGCCATGAAGAACGTGGCGCCGGTGCGCAAGGAGCTGGGCGTGCGGACCATTTTCAACATCCTGGGGCCGCTGAC
CAACCCGGCAGGTGCGCCCAACATCCTCATGGGCGTGTTCCACGAAGACCTGGTGGGCATCCAGGTGCGTGCGCTGCAAC
GCCTGGGCGCCGAGCACGCGCTGGTGGTCTACGGCCGTGACGGGCTGGACGAAATCAGCCTGGGCGCGGGCACGCTGGTG
GGCGAATTGAAAGACGGCGCGGTGCGCGAGTACGAGATCCACCCCGAGGACTTCGGCCTGCGCATGGCAGGCACGCGGGC
GCTGCGCGTGGAGAACCCGACCGAATCCAAGGCCATGCTGATGGGCGTGCTGCAGGGCGACGAAGGCCCGGCGCGCGACA
TCGTCTGCCTGAATGCCGGTGCCGCCTTGTATGCTGCCAACGTGGCCGACTCGCTGGAAGACGGCCTGCGCCGCGCCCAG
CAGGCCCTGGCCAGCGGCGCGGCCCTGGCCAAGCTGCAGCAGCTGGTCGCCTACACCCAGAAGCTCGCGGCCTGA

Upstream 100 bases:

>100_bases
TAAGAGCTGCCAGCGCTTGCCTATAAACGATTTCAGTGTGAAAAATGCTTGAAATGCATATACAGCAAGCGCACGCAGCT
ATCAAAATAGAGGTACTTCC

Downstream 100 bases:

>100_bases
GCGCACGGCGATGAGCTTGCTGGACGCTCCCATCTGGAACGACCCCGCGACGTGGATCGTGCTGGGCGTGTCGCTGCTGT
TCATCGTCGTGGGCATCGTG

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MTPITPQEALQRTIEHREIFHDEMLHLMRMIMSGELSPVMTAAITTGLRVKKETIGEITAAAQVMREFSHKVQVHDTKHL
VDIVGTGGDGANTFNISTCATFVIAAAGAKVSKHGGRSVSSKSGSADAMEALGVHINLQPAQIAQCIGDVGIGFMFAPNH
HPAMKNVAPVRKELGVRTIFNILGPLTNPAGAPNILMGVFHEDLVGIQVRALQRLGAEHALVVYGRDGLDEISLGAGTLV
GELKDGAVREYEIHPEDFGLRMAGTRALRVENPTESKAMLMGVLQGDEGPARDIVCLNAGAALYAANVADSLEDGLRRAQ
QALASGAALAKLQQLVAYTQKLAA

Sequences:

>Translated_344_residues
MTPITPQEALQRTIEHREIFHDEMLHLMRMIMSGELSPVMTAAITTGLRVKKETIGEITAAAQVMREFSHKVQVHDTKHL
VDIVGTGGDGANTFNISTCATFVIAAAGAKVSKHGGRSVSSKSGSADAMEALGVHINLQPAQIAQCIGDVGIGFMFAPNH
HPAMKNVAPVRKELGVRTIFNILGPLTNPAGAPNILMGVFHEDLVGIQVRALQRLGAEHALVVYGRDGLDEISLGAGTLV
GELKDGAVREYEIHPEDFGLRMAGTRALRVENPTESKAMLMGVLQGDEGPARDIVCLNAGAALYAANVADSLEDGLRRAQ
QALASGAALAKLQQLVAYTQKLAA
>Mature_343_residues
TPITPQEALQRTIEHREIFHDEMLHLMRMIMSGELSPVMTAAITTGLRVKKETIGEITAAAQVMREFSHKVQVHDTKHLV
DIVGTGGDGANTFNISTCATFVIAAAGAKVSKHGGRSVSSKSGSADAMEALGVHINLQPAQIAQCIGDVGIGFMFAPNHH
PAMKNVAPVRKELGVRTIFNILGPLTNPAGAPNILMGVFHEDLVGIQVRALQRLGAEHALVVYGRDGLDEISLGAGTLVG
ELKDGAVREYEIHPEDFGLRMAGTRALRVENPTESKAMLMGVLQGDEGPARDIVCLNAGAALYAANVADSLEDGLRRAQQ
ALASGAALAKLQQLVAYTQKLAA

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=282, Percent_Identity=40.0709219858156, Blast_Score=188, Evalue=4e-49,
Organism=Saccharomyces cerevisiae, GI6320561, Length=326, Percent_Identity=31.2883435582822, Blast_Score=137, Evalue=3e-33,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_ACIET (B9MBS3)

Other databases:

- EMBL:   CP001392
- RefSeq:   YP_002551843.1
- ProteinModelPortal:   B9MBS3
- SMR:   B9MBS3
- GeneID:   7385367
- GenomeReviews:   CP001392_GR
- KEGG:   dia:Dtpsy_0359
- ProtClustDB:   PRK00188
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 36474; Mature: 36342

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPITPQEALQRTIEHREIFHDEMLHLMRMIMSGELSPVMTAAITTGLRVKKETIGEITA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHH
AAQVMREFSHKVQVHDTKHLVDIVGTGGDGANTFNISTCATFVIAAAGAKVSKHGGRSVS
HHHHHHHHHHCEEECCHHEEEEEEECCCCCCCEEEHHHHHHHHHHHCCCHHHHCCCCCCC
SKSGSADAMEALGVHINLQPAQIAQCIGDVGIGFMFAPNHHPAMKNVAPVRKELGVRTIF
CCCCCHHHHHHHCCEEECCHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHHHHH
NILGPLTNPAGAPNILMGVFHEDLVGIQVRALQRLGAEHALVVYGRDGLDEISLGAGTLV
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHCCCCHHH
GELKDGAVREYEIHPEDFGLRMAGTRALRVENPTESKAMLMGVLQGDEGPARDIVCLNAG
HHCCCCCEEEEEECCCCCCEEEECCEEEEECCCCHHHHHHHHHHCCCCCCCCCEEEEECC
AALYAANVADSLEDGLRRAQQALASGAALAKLQQLVAYTQKLAA
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TPITPQEALQRTIEHREIFHDEMLHLMRMIMSGELSPVMTAAITTGLRVKKETIGEITA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHH
AAQVMREFSHKVQVHDTKHLVDIVGTGGDGANTFNISTCATFVIAAAGAKVSKHGGRSVS
HHHHHHHHHHCEEECCHHEEEEEEECCCCCCCEEEHHHHHHHHHHHCCCHHHHCCCCCCC
SKSGSADAMEALGVHINLQPAQIAQCIGDVGIGFMFAPNHHPAMKNVAPVRKELGVRTIF
CCCCCHHHHHHHCCEEECCHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHHHHH
NILGPLTNPAGAPNILMGVFHEDLVGIQVRALQRLGAEHALVVYGRDGLDEISLGAGTLV
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHCCCCHHH
GELKDGAVREYEIHPEDFGLRMAGTRALRVENPTESKAMLMGVLQGDEGPARDIVCLNAG
HHCCCCCEEEEEECCCCCCEEEECCEEEEECCCCHHHHHHHHHHCCCCCCCCCEEEEECC
AALYAANVADSLEDGLRRAQQALASGAALAKLQQLVAYTQKLAA
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA