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The map label for this gene is mreB [H]

Identifier: 222109453

GI number: 222109453

Start: 252408

End: 253451

Strand: Direct

Name: mreB [H]

Synonym: Dtpsy_0233

Alternate gene names: 222109453

Gene position: 252408-253451 (Clockwise)

Preceding gene: 222109449

Following gene: 222109454

Centisome position: 6.65

GC content: 66.57

Gene sequence:

>1044_bases
ATGTTCGGAGCTTTCCGTCGGTACTTCTCCACCGACCTGGCCATTGACCTTGGCACAGCCAACACCCTGATCTTCGCCCG
CGACAAGGGCATCGTGCTCGACGAGCCCTCCGTCGTCGCCATCCGCCACGAGGGCGGCCCGCACGGCAAGAAAGTGATCC
AGGCCGTGGGCCACGAGGCCAAGGCCATGCTGGGCAAAGTGCCTGGCAACATCGAGGCCATCCGCCCGATGAAGGACGGC
GTGATTGCCGATTTCGTGATCACCGAGCAGATGATCAAGCAGTTCATCAAGATGGTGCATCCCCGCTCGGTGCTCACGCC
CAGCCCGCGCATCATCATCTGCGTGCCCTGCGGCTCCACCCAGGTGGAGCGCCGCGCCATCAAGGACGCGGCCGAAGCGG
CCGGCGCCACCGCCGTGTACCTGATCGAAGAGCCCATGGCCGCCGGTATCGGCGCGGGCCTGCCGGTGTCCGAGGCCTCT
GGCTCCATGGTGGTGGACATCGGCGGCGGCACCACCGAGGTCGGCGTGATTTCGCTGGGCGGCATGGTCTACAAGGGCAG
CGTGCGCGTGGGTGGCGACAAGTTCGACGAATCCATCATCAATTACATCCGCCGCAACTACGGCATGCTGATCGGCGAGC
CGACGGCCGAGGCCATCAAGAAGAACATCGGCTCTGCCTTCCCTGGCTCCGAGGTCAAGGAGATGGAGGTCAAGGGCCGC
AACCTCTCCGAGGGCGTGCCGCGCAGCTTCACCATCTCGTCCAACGAGGTGCTGGAGGCCCTGACCGAGCCGCTCAACCA
GATCGTCTCCGCCGTCAAGAACGCGCTGGAGCAGACCCCGCCGGAGCTGGGCGCCGACATTGCCGAGCGCGGCATGATGC
TCACCGGCGGCGGCGCGCTGCTGCGCGACCTGGACCGTTTGCTGGCCGAGGAAACCGGCCTGCCCGTATTGGTGGCCGAG
GAGCCCCTGACCTGCGTGGTGCGCGGCTGCGGCATCGCGCTGGAGCGCATGGACCGCCAGGGCAGCATCTTCACCAGCGA
CTGA

Upstream 100 bases:

>100_bases
CTCCATATTGCCGGTCATAGTGCGAAAAAAGCCAACAAACACCCCGTAATATCCGGCGACGGCAGGCCGACGTGCATGCC
GTGCCTGAGAGGACCCCTGC

Downstream 100 bases:

>100_bases
GTCCGAACCGCGCCTGACGAGCTGTCCGCATGCCACTGGGAACCCTGGACCGTTCGGCGCCGACGCTGTTCAAGCAGGGG
CCATCGCCGCTCTCCCGCCT

Product: rod shape-determining protein mreb

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MFGAFRRYFSTDLAIDLGTANTLIFARDKGIVLDEPSVVAIRHEGGPHGKKVIQAVGHEAKAMLGKVPGNIEAIRPMKDG
VIADFVITEQMIKQFIKMVHPRSVLTPSPRIIICVPCGSTQVERRAIKDAAEAAGATAVYLIEEPMAAGIGAGLPVSEAS
GSMVVDIGGGTTEVGVISLGGMVYKGSVRVGGDKFDESIINYIRRNYGMLIGEPTAEAIKKNIGSAFPGSEVKEMEVKGR
NLSEGVPRSFTISSNEVLEALTEPLNQIVSAVKNALEQTPPELGADIAERGMMLTGGGALLRDLDRLLAEETGLPVLVAE
EPLTCVVRGCGIALERMDRQGSIFTSD

Sequences:

>Translated_347_residues
MFGAFRRYFSTDLAIDLGTANTLIFARDKGIVLDEPSVVAIRHEGGPHGKKVIQAVGHEAKAMLGKVPGNIEAIRPMKDG
VIADFVITEQMIKQFIKMVHPRSVLTPSPRIIICVPCGSTQVERRAIKDAAEAAGATAVYLIEEPMAAGIGAGLPVSEAS
GSMVVDIGGGTTEVGVISLGGMVYKGSVRVGGDKFDESIINYIRRNYGMLIGEPTAEAIKKNIGSAFPGSEVKEMEVKGR
NLSEGVPRSFTISSNEVLEALTEPLNQIVSAVKNALEQTPPELGADIAERGMMLTGGGALLRDLDRLLAEETGLPVLVAE
EPLTCVVRGCGIALERMDRQGSIFTSD
>Mature_347_residues
MFGAFRRYFSTDLAIDLGTANTLIFARDKGIVLDEPSVVAIRHEGGPHGKKVIQAVGHEAKAMLGKVPGNIEAIRPMKDG
VIADFVITEQMIKQFIKMVHPRSVLTPSPRIIICVPCGSTQVERRAIKDAAEAAGATAVYLIEEPMAAGIGAGLPVSEAS
GSMVVDIGGGTTEVGVISLGGMVYKGSVRVGGDKFDESIINYIRRNYGMLIGEPTAEAIKKNIGSAFPGSEVKEMEVKGR
NLSEGVPRSFTISSNEVLEALTEPLNQIVSAVKNALEQTPPELGADIAERGMMLTGGGALLRDLDRLLAEETGLPVLVAE
EPLTCVVRGCGIALERMDRQGSIFTSD

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI87082236, Length=349, Percent_Identity=69.3409742120344, Blast_Score=488, Evalue=1e-139,
Organism=Escherichia coli, GI1788875, Length=104, Percent_Identity=34.6153846153846, Blast_Score=65, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6323401, Length=265, Percent_Identity=25.2830188679245, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001023
- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 36788; Mature: 36788

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGAFRRYFSTDLAIDLGTANTLIFARDKGIVLDEPSVVAIRHEGGPHGKKVIQAVGHEA
CCHHHHHHHCCCCEEEECCCCEEEEEECCCEEECCCCEEEEECCCCCHHHHHHHHHCHHH
KAMLGKVPGNIEAIRPMKDGVIADFVITEQMIKQFIKMVHPRSVLTPSPRIIICVPCGST
HHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCH
QVERRAIKDAAEAAGATAVYLIEEPMAAGIGAGLPVSEASGSMVVDIGGGTTEVGVISLG
HHHHHHHHHHHHHCCCEEEEEECCCHHHCCCCCCCCCCCCCCEEEEECCCCCEEEEEEEC
GMVYKGSVRVGGDKFDESIINYIRRNYGMLIGEPTAEAIKKNIGSAFPGSEVKEMEVKGR
CEEEECCEEECCCHHHHHHHHHHHHHCCEEEECCHHHHHHHHHCCCCCCCCCHHHHHCCC
NLSEGVPRSFTISSNEVLEALTEPLNQIVSAVKNALEQTPPELGADIAERGMMLTGGGAL
CCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHCCEEEECCHHH
LRDLDRLLAEETGLPVLVAEEPLTCVVRGCGIALERMDRQGSIFTSD
HHHHHHHHHHHCCCEEEEECCCCEEHHHHHHHHHHHHCCCCCEEECC
>Mature Secondary Structure
MFGAFRRYFSTDLAIDLGTANTLIFARDKGIVLDEPSVVAIRHEGGPHGKKVIQAVGHEA
CCHHHHHHHCCCCEEEECCCCEEEEEECCCEEECCCCEEEEECCCCCHHHHHHHHHCHHH
KAMLGKVPGNIEAIRPMKDGVIADFVITEQMIKQFIKMVHPRSVLTPSPRIIICVPCGST
HHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCH
QVERRAIKDAAEAAGATAVYLIEEPMAAGIGAGLPVSEASGSMVVDIGGGTTEVGVISLG
HHHHHHHHHHHHHCCCEEEEEECCCHHHCCCCCCCCCCCCCCEEEEECCCCCEEEEEEEC
GMVYKGSVRVGGDKFDESIINYIRRNYGMLIGEPTAEAIKKNIGSAFPGSEVKEMEVKGR
CEEEECCEEECCCHHHHHHHHHHHHHCCEEEECCHHHHHHHHHCCCCCCCCCHHHHHCCC
NLSEGVPRSFTISSNEVLEALTEPLNQIVSAVKNALEQTPPELGADIAERGMMLTGGGAL
CCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHCCEEEECCHHH
LRDLDRLLAEETGLPVLVAEEPLTCVVRGCGIALERMDRQGSIFTSD
HHHHHHHHHHHCCCEEEEECCCCEEHHHHHHHHHHHHCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]