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The map label for this gene is dnaQ [H]

Identifier: 222109241

GI number: 222109241

Start: 15687

End: 16343

Strand: Direct

Name: dnaQ [H]

Synonym: Dtpsy_0016

Alternate gene names: 222109241

Gene position: 15687-16343 (Clockwise)

Preceding gene: 222109240

Following gene: 222109242

Centisome position: 0.41

GC content: 71.23

Gene sequence:

>657_bases
ATGCCGTCCGCCCCCATCGCCGTCATCGATTTCGAAACCACCGGCATGATGCCTGCCCAGGGTGCACGCGCCACCGAGGT
GGCCATCGTGCTCATGGAAGGCGGCCGCGTGGTGGACCGCTACCAGAGCCTGATGCGCACGGGCGTGCGGATTCCGCCCT
TCATCACGCAACTCACCGGCATCACGAATGCCATGGTGGAGGCCGCCCCCGATGCCGCCGCAGTGATGCGCGAGGCCGCG
CGCTTCGTGGGCGACGCGCCCATGGTGGCCCACAACGCCGCATTCGACCGCAAGTTCTGGCAGGCGGAAATGCAGCACGC
CGGGCTCGCCGCGCCCCATCCGTTCGCCTGCACCGTGCTGCTGTCGCGCCGCGTGTACCCCGATGCGCCCAGCCACAGCC
TGGGCCGCCTCACGGACCACCTCGGCCTGCCGCGCGCCGGGCGCGCCCACCGCGCGCTGGCCGATGCGGAAATGGCCGCC
GCGCTGCTGGCCTGTATGCAGCGTGACCTGTGCCAACGCTTCGGCCTGGCCTGGCCGGACCACGCGCTGCTGATGCAGTT
GCAGCGCTGCGCACGCCCTGCCATCGGCAAGCTGCTGCAGCGCCACCGCCAGGCCGCGCCAGCCGAACAGCCGCCAACGG
CGTTGCAAATGGGGTAG

Upstream 100 bases:

>100_bases
GGCGGCGGCGCTTCGTGCGTGGCGACTACGATTACGCACCGGTGCCGGTGGCCCGTGCCTATCGCACGGGGTGCGCGGGG
CCGGTTTCCTGCCGTCCCGC

Downstream 100 bases:

>100_bases
CTGCCCGCGCCGTTGCCGCGGGCGCGGCAGGGCATTTTTCATCCTTCTCCCATTCATACCGCGCGTCGGATTGCGCGCAC
ATCCAGGCGTGACCGGGGCC

Product: DNA-directed DNA polymerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MPSAPIAVIDFETTGMMPAQGARATEVAIVLMEGGRVVDRYQSLMRTGVRIPPFITQLTGITNAMVEAAPDAAAVMREAA
RFVGDAPMVAHNAAFDRKFWQAEMQHAGLAAPHPFACTVLLSRRVYPDAPSHSLGRLTDHLGLPRAGRAHRALADAEMAA
ALLACMQRDLCQRFGLAWPDHALLMQLQRCARPAIGKLLQRHRQAAPAEQPPTALQMG

Sequences:

>Translated_218_residues
MPSAPIAVIDFETTGMMPAQGARATEVAIVLMEGGRVVDRYQSLMRTGVRIPPFITQLTGITNAMVEAAPDAAAVMREAA
RFVGDAPMVAHNAAFDRKFWQAEMQHAGLAAPHPFACTVLLSRRVYPDAPSHSLGRLTDHLGLPRAGRAHRALADAEMAA
ALLACMQRDLCQRFGLAWPDHALLMQLQRCARPAIGKLLQRHRQAAPAEQPPTALQMG
>Mature_217_residues
PSAPIAVIDFETTGMMPAQGARATEVAIVLMEGGRVVDRYQSLMRTGVRIPPFITQLTGITNAMVEAAPDAAAVMREAAR
FVGDAPMVAHNAAFDRKFWQAEMQHAGLAAPHPFACTVLLSRRVYPDAPSHSLGRLTDHLGLPRAGRAHRALADAEMAAA
LLACMQRDLCQRFGLAWPDHALLMQLQRCARPAIGKLLQRHRQAAPAEQPPTALQMG

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 23589; Mature: 23458

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
6.0 %Met     (Translated Protein)
7.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSAPIAVIDFETTGMMPAQGARATEVAIVLMEGGRVVDRYQSLMRTGVRIPPFITQLTG
CCCCCEEEEEECCCCCCCCCCCCHHEEEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHH
ITNAMVEAAPDAAAVMREAARFVGDAPMVAHNAAFDRKFWQAEMQHAGLAAPHPFACTVL
HHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
LSRRVYPDAPSHSLGRLTDHLGLPRAGRAHRALADAEMAAALLACMQRDLCQRFGLAWPD
HHHCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
HALLMQLQRCARPAIGKLLQRHRQAAPAEQPPTALQMG
HHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
PSAPIAVIDFETTGMMPAQGARATEVAIVLMEGGRVVDRYQSLMRTGVRIPPFITQLTG
CCCCEEEEEECCCCCCCCCCCCHHEEEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHH
ITNAMVEAAPDAAAVMREAARFVGDAPMVAHNAAFDRKFWQAEMQHAGLAAPHPFACTVL
HHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
LSRRVYPDAPSHSLGRLTDHLGLPRAGRAHRALADAEMAAALLACMQRDLCQRFGLAWPD
HHHCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
HALLMQLQRCARPAIGKLLQRHRQAAPAEQPPTALQMG
HHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]