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The map label for this gene is dinG [H]

Identifier: 222109239

GI number: 222109239

Start: 12968

End: 15157

Strand: Direct

Name: dinG [H]

Synonym: Dtpsy_0014

Alternate gene names: 222109239

Gene position: 12968-15157 (Clockwise)

Preceding gene: 222109237

Following gene: 222109240

Centisome position: 0.34

GC content: 72.15

Gene sequence:

>2190_bases
ATGTCTTCCACAGAGTGGGCCGCCCAGGCCCTGCAATCGTTCGAGGCGGTGGTCCAGTCCACGGCCGGCTTTCGCGTGCG
CGAGGGCCAGCGGCGCATGGCCGAGCAGGTGGCCCAGACCTTCAGCCAGGCGCAGCTGGGCAAGCTGGAGGACGACGATG
CCCTGCCCCAGCGCGCGATTGCCGTGGTGCAGGCCGGCACGGGCGTGGGCAAGTCGCTGGCCTACAGCGTGCCCGCGATC
GCGATGGCGCTGGCGCGCGGTACGCGGGTGCTGATCTCCACCGCCACCGTGGCGCTGCAGGAGCAACTGGTGCACAAGGA
CCTGCCGGCCCTGGCCGCACGCATGGAGCTACCCTTCCAGTTCGCGCTGGCCAAGGGACGCGGGCGCTATGTGTGCAAGC
TCAAGCTGGAGCGCCTGGCCGGCGGCGGCGCGGCCGGCCCGGGCGGTGACGGCGACCTGCCCGACGACGACCTGTTCGCC
GACGAGGAGGCCGAGCAGCGCGGCAAGCGCCCGCGCCACGAGTCCGAGGCGCGCATGAAGTTCTACGCCAGCATGGCCGA
CGCGCTGGCGACCAGCGAATGGGACGGCGACCGCGACACGCTCGCTACGCCGCCCGAGCCCGAGGCCTGGAGTCCCGTGG
CGGCCGAGGCCAGTTCCTGCACCGGCAAGCACTGCCCGGTGTTCAACCAGTGCACCTACTACGAGCGGCGCAAGCAGCTC
GTGGCCGCGCAGGTCATCGTGGCCAACCACGACCTGCTGCTGTCGTCCCTGGGCGCGCGTCTGCTGCCCGAGCTGGACAA
CTGCCTGCTGGTGATCGACGAGGCCCACCACCTGCCCGCCACCGCGCTCGACCAGTTCGCCTGCGAGGCCGACCTCTCGC
GCCTGACCTGGATCGACCGCCTGGCCAGCCGCGCGCTGCGCATCGGCCAGCTGGTGGAGGTCGAGGAAATTGCCGACATT
CCCAACCACGCCGCGCGCCTGCGCGCCGCGCTGCAGGATGCCGCGCGCCTGGTGATGGACGTGTATGGCGAGCAACTGCG
TGCGCCCGTGCCGGGGCGCCGCCAGTTCGCATCCAGCCTGCCCACGCGCGCCCGCGTGGCCGGCGGTGTGCTGCCCGAAG
CGTTGGTGGAGCCCTTCAGCCAGGCCGCGCACCACGCCGAGGGCTTCCTGAACGCCCTGCGCGCCATTTCCAAGGCCCTG
CGCAGCGAAATGCGCGACAAGCCGGACGAGGCGCGGCGCCTATCGCAGCTGTATGCGCAGATCGGCGTGCTGGCGCCGCG
GCTGGAGGCCGTGCACGCGGCCGCCCAGTTGCTGCTGCAGGACGCGCCCGAGGGCGCGGTGCCGGCCGCCAAGTGGTTCA
CGCTGGAGGTCGAGGGCGACTTCATCGTCGTGCGCGCGCATGCCAGCCCCGTGCTGCCGGGCAATACGTTGCGCAACCAC
CTGTGGTCCGCCGTGCGCGGCGCGGTGCTGACCTCGGCCACGCTCACCAGTTGCGGGCAGTTCGACTTCTTCCTGCGCGA
ATCGGGCCTGTTCGGCGACGAAGCCGTGACCACGCTGGCCGTGCCCAGCCCGTTCGACTACGCGCTGCAGGGCACGCTGG
TGGCCACCGAGACCCGCGCCGAGCCGCGCGATGCGCAGGCCTTCACCGCCGAGATGGTGGACGCGCTGCTGTCCGACCTG
GCCCTGGTCGAGGCCGGCGCGCTGGTGCTGTTCACCTCGCGCGAGCAAATGCGCCAGGCCGTGGACATGCTGCCCACCGC
CATGCGCAGCGCCGTGCTGGTGCAAAACACCCTGCCCCGCCCACAGCTGCTGGCCCGCCACCGCGAGCGCGTGGCCGAGG
GCCTGCCGTCCATCATCTTCGGCATGCAATCCTTCGGCGAGGGGCTGGACCTGCCCGGCAGGCTGTGCGAATCGCTCTTC
ATCACCAAGCTGCCCTTCGCCCCGCCCGACGACCCCGTGGGCGAGGCCCGCGCCGAATGGCTGCGCGGGGCCGGGCGCGA
CCCGTTCAGCGAACTGGTGGTGCCGGCCACCGCCATCCGCCTGGCACAGTGGGTGGGTCGCGCCATCCGCACCGAGGAAG
ACCGCGCCCACGTGTATTGCTACGACAAGCGCCTGGTGCGCACCGGCTACGGCCAGCGGCTGCTGCAGGGCTTGCCGCCG
TTCACGCTGGCGCGCCGGGCCGCAGGGTGA

Upstream 100 bases:

>100_bases
CCGGCCCTCAGCAGTGCCCAGCCCGCTTCGGCTAACATGCCTGGATGCATTTACAGTGGCACGCCCCGCAAAGCCGGCCC
CGCGCCTGATCTCCCCTTCC

Downstream 100 bases:

>100_bases
CCGATTGCTCCTATGGATATAGCTGGTGGCGCTTGCTGGATAAGCGCTGGAGCCCGATTGGACCATTAACCCCTTCCCGC
ATCGCCTGTCGGGCCGCGTC

Product: ATP-dependent DNA helicase ding

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 729; Mature: 728

Protein sequence:

>729_residues
MSSTEWAAQALQSFEAVVQSTAGFRVREGQRRMAEQVAQTFSQAQLGKLEDDDALPQRAIAVVQAGTGVGKSLAYSVPAI
AMALARGTRVLISTATVALQEQLVHKDLPALAARMELPFQFALAKGRGRYVCKLKLERLAGGGAAGPGGDGDLPDDDLFA
DEEAEQRGKRPRHESEARMKFYASMADALATSEWDGDRDTLATPPEPEAWSPVAAEASSCTGKHCPVFNQCTYYERRKQL
VAAQVIVANHDLLLSSLGARLLPELDNCLLVIDEAHHLPATALDQFACEADLSRLTWIDRLASRALRIGQLVEVEEIADI
PNHAARLRAALQDAARLVMDVYGEQLRAPVPGRRQFASSLPTRARVAGGVLPEALVEPFSQAAHHAEGFLNALRAISKAL
RSEMRDKPDEARRLSQLYAQIGVLAPRLEAVHAAAQLLLQDAPEGAVPAAKWFTLEVEGDFIVVRAHASPVLPGNTLRNH
LWSAVRGAVLTSATLTSCGQFDFFLRESGLFGDEAVTTLAVPSPFDYALQGTLVATETRAEPRDAQAFTAEMVDALLSDL
ALVEAGALVLFTSREQMRQAVDMLPTAMRSAVLVQNTLPRPQLLARHRERVAEGLPSIIFGMQSFGEGLDLPGRLCESLF
ITKLPFAPPDDPVGEARAEWLRGAGRDPFSELVVPATAIRLAQWVGRAIRTEEDRAHVYCYDKRLVRTGYGQRLLQGLPP
FTLARRAAG

Sequences:

>Translated_729_residues
MSSTEWAAQALQSFEAVVQSTAGFRVREGQRRMAEQVAQTFSQAQLGKLEDDDALPQRAIAVVQAGTGVGKSLAYSVPAI
AMALARGTRVLISTATVALQEQLVHKDLPALAARMELPFQFALAKGRGRYVCKLKLERLAGGGAAGPGGDGDLPDDDLFA
DEEAEQRGKRPRHESEARMKFYASMADALATSEWDGDRDTLATPPEPEAWSPVAAEASSCTGKHCPVFNQCTYYERRKQL
VAAQVIVANHDLLLSSLGARLLPELDNCLLVIDEAHHLPATALDQFACEADLSRLTWIDRLASRALRIGQLVEVEEIADI
PNHAARLRAALQDAARLVMDVYGEQLRAPVPGRRQFASSLPTRARVAGGVLPEALVEPFSQAAHHAEGFLNALRAISKAL
RSEMRDKPDEARRLSQLYAQIGVLAPRLEAVHAAAQLLLQDAPEGAVPAAKWFTLEVEGDFIVVRAHASPVLPGNTLRNH
LWSAVRGAVLTSATLTSCGQFDFFLRESGLFGDEAVTTLAVPSPFDYALQGTLVATETRAEPRDAQAFTAEMVDALLSDL
ALVEAGALVLFTSREQMRQAVDMLPTAMRSAVLVQNTLPRPQLLARHRERVAEGLPSIIFGMQSFGEGLDLPGRLCESLF
ITKLPFAPPDDPVGEARAEWLRGAGRDPFSELVVPATAIRLAQWVGRAIRTEEDRAHVYCYDKRLVRTGYGQRLLQGLPP
FTLARRAAG
>Mature_728_residues
SSTEWAAQALQSFEAVVQSTAGFRVREGQRRMAEQVAQTFSQAQLGKLEDDDALPQRAIAVVQAGTGVGKSLAYSVPAIA
MALARGTRVLISTATVALQEQLVHKDLPALAARMELPFQFALAKGRGRYVCKLKLERLAGGGAAGPGGDGDLPDDDLFAD
EEAEQRGKRPRHESEARMKFYASMADALATSEWDGDRDTLATPPEPEAWSPVAAEASSCTGKHCPVFNQCTYYERRKQLV
AAQVIVANHDLLLSSLGARLLPELDNCLLVIDEAHHLPATALDQFACEADLSRLTWIDRLASRALRIGQLVEVEEIADIP
NHAARLRAALQDAARLVMDVYGEQLRAPVPGRRQFASSLPTRARVAGGVLPEALVEPFSQAAHHAEGFLNALRAISKALR
SEMRDKPDEARRLSQLYAQIGVLAPRLEAVHAAAQLLLQDAPEGAVPAAKWFTLEVEGDFIVVRAHASPVLPGNTLRNHL
WSAVRGAVLTSATLTSCGQFDFFLRESGLFGDEAVTTLAVPSPFDYALQGTLVATETRAEPRDAQAFTAEMVDALLSDLA
LVEAGALVLFTSREQMRQAVDMLPTAMRSAVLVQNTLPRPQLLARHRERVAEGLPSIIFGMQSFGEGLDLPGRLCESLFI
TKLPFAPPDDPVGEARAEWLRGAGRDPFSELVVPATAIRLAQWVGRAIRTEEDRAHVYCYDKRLVRTGYGQRLLQGLPPF
TLARRAAG

Specific function: Probable helicase involved in DNA repair and perhaps also replication [H]

COG id: COG1199

COG function: function code KL; Rad3-related DNA helicases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787018, Length=726, Percent_Identity=30.9917355371901, Blast_Score=286, Evalue=3e-78,
Organism=Escherichia coli, GI1788110, Length=329, Percent_Identity=30.0911854103343, Blast_Score=122, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010614
- InterPro:   IPR014013
- InterPro:   IPR006555
- InterPro:   IPR001650 [H]

Pfam domain/function: PF06733 DEAD_2 [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 79164; Mature: 79033

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSTEWAAQALQSFEAVVQSTAGFRVREGQRRMAEQVAQTFSQAQLGKLEDDDALPQRAI
CCCHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
AVVQAGTGVGKSLAYSVPAIAMALARGTRVLISTATVALQEQLVHKDLPALAARMELPFQ
HHHCCCCCCCHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
FALAKGRGRYVCKLKLERLAGGGAAGPGGDGDLPDDDLFADEEAEQRGKRPRHESEARMK
HHHHCCCCCEEEEEEHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHH
FYASMADALATSEWDGDRDTLATPPEPEAWSPVAAEASSCTGKHCPVFNQCTYYERRKQL
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHH
VAAQVIVANHDLLLSSLGARLLPELDNCLLVIDEAHHLPATALDQFACEADLSRLTWIDR
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
LASRALRIGQLVEVEEIADIPNHAARLRAALQDAARLVMDVYGEQLRAPVPGRRQFASSL
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCC
PTRARVAGGVLPEALVEPFSQAAHHAEGFLNALRAISKALRSEMRDKPDEARRLSQLYAQ
CHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
IGVLAPRLEAVHAAAQLLLQDAPEGAVPAAKWFTLEVEGDFIVVRAHASPVLPGNTLRNH
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCEEEEEECCCCCCCCHHHHHH
LWSAVRGAVLTSATLTSCGQFDFFLRESGLFGDEAVTTLAVPSPFDYALQGTLVATETRA
HHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCHHHEEEECCCCCCHHHCCEEEEECCCC
EPRDAQAFTAEMVDALLSDLALVEAGALVLFTSREQMRQAVDMLPTAMRSAVLVQNTLPR
CCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCC
PQLLARHRERVAEGLPSIIFGMQSFGEGLDLPGRLCESLFITKLPFAPPDDPVGEARAEW
HHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
LRGAGRDPFSELVVPATAIRLAQWVGRAIRTEEDRAHVYCYDKRLVRTGYGQRLLQGLPP
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHCHHHHHHHCCCC
FTLARRAAG
HHHHHHCCC
>Mature Secondary Structure 
SSTEWAAQALQSFEAVVQSTAGFRVREGQRRMAEQVAQTFSQAQLGKLEDDDALPQRAI
CCHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
AVVQAGTGVGKSLAYSVPAIAMALARGTRVLISTATVALQEQLVHKDLPALAARMELPFQ
HHHCCCCCCCHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
FALAKGRGRYVCKLKLERLAGGGAAGPGGDGDLPDDDLFADEEAEQRGKRPRHESEARMK
HHHHCCCCCEEEEEEHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHH
FYASMADALATSEWDGDRDTLATPPEPEAWSPVAAEASSCTGKHCPVFNQCTYYERRKQL
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHH
VAAQVIVANHDLLLSSLGARLLPELDNCLLVIDEAHHLPATALDQFACEADLSRLTWIDR
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
LASRALRIGQLVEVEEIADIPNHAARLRAALQDAARLVMDVYGEQLRAPVPGRRQFASSL
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCC
PTRARVAGGVLPEALVEPFSQAAHHAEGFLNALRAISKALRSEMRDKPDEARRLSQLYAQ
CHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
IGVLAPRLEAVHAAAQLLLQDAPEGAVPAAKWFTLEVEGDFIVVRAHASPVLPGNTLRNH
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCEEEEEECCCCCCCCHHHHHH
LWSAVRGAVLTSATLTSCGQFDFFLRESGLFGDEAVTTLAVPSPFDYALQGTLVATETRA
HHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCHHHEEEECCCCCCHHHCCEEEEECCCC
EPRDAQAFTAEMVDALLSDLALVEAGALVLFTSREQMRQAVDMLPTAMRSAVLVQNTLPR
CCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCC
PQLLARHRERVAEGLPSIIFGMQSFGEGLDLPGRLCESLFITKLPFAPPDDPVGEARAEW
HHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
LRGAGRDPFSELVVPATAIRLAQWVGRAIRTEEDRAHVYCYDKRLVRTGYGQRLLQGLPP
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHCHHHHHHHCCCC
FTLARRAAG
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8396546; 8385320 [H]