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The map label for this gene is feaR [H]

Identifier: 222102893

GI number: 222102893

Start: 572212

End: 573078

Strand: Direct

Name: feaR [H]

Synonym: Avi_7635

Alternate gene names: 222102893

Gene position: 572212-573078 (Clockwise)

Preceding gene: 222102892

Following gene: 222102895

Centisome position: 90.57

GC content: 56.86

Gene sequence:

>867_bases
CTGTGCAACGTCTATGTCGCGCTCGATCCAGAAACACCGTCCAAAATGGACTTCCGAGGTGCTGTAACCGATCACCCGTT
CGACGAAATCGGCATTTCGAATATCGCGTCGCTGAAACAGACCATTGCACGCACGACAAGCGGCATACGCCGCGACACGA
ATGCCTATTGTTTCCTCAATCTGCAAGTGGCCGGCACATGCCGCATCCGTCAGGGAAACCGCGATGCCATCACGATGCCC
GGGGAGTTCACCGTCGTCGATTCGTCCGAACCGTTTCTTCTCGACTATACGAGCGACACTTGGGAACAATATGCGTTCAA
GATCCCGAAGCATATGTTTGATTCCCATGTCGGCCACGAATTCGTGGCGCGCACAGTCACGGACCGCACACCCATCGGCA
AGGTCGTTGTCGATTTTCTGGCATCCATCGCCCGAAACCCCGAGAATCTGCGCCACAGCTCGATCAATATGACGAAGACA
ATCATCGACCTTGTTGCCATGTCGCTTCGAGCCTCGACGCCCGAGCGTGACGACGATCGCCGCCGGACCTTCAGGTCACC
CCTTCGTCAGTCTGTTCTACGCTATGTCGAGCTTAACTTCGCAGACCCGGAGATCTCACCCGCCAAGGTCGCGGCTCATT
TCGGAATATCGACCCGCTACCTGCACAAGCTGCTGGAAGAACACGGCGAGACCTTGGGGCAGATCATCCTGGCAAAGCGC
CTCGATCGTTGCGCCTCCGAACTGCGTAAAGGGACATGCCTGACCATTTCGGAAGCAGCCTTCCGCTGGGGTTTCAACGA
CATGTCCTATTTCAGCAGAGCCTTCCGGCGACGTTTCGGCGTTGCCCCCCGCGATTACAGGCGATGA

Upstream 100 bases:

>100_bases
GTTTGTGACGTCCCAACAAAGGCAGCACGATATGCATATGAGGTGTTTCGATCTGGGTGAGATCAGGACGGCAGAGCGCT
TTAGCTACTGGAGGGACGTT

Downstream 100 bases:

>100_bases
CCGCAACAGAACCGCAGCTCTGCCGCTGTACGGCAAAGCTGCGCTAGGCTTGATTATCGTTCAGGCAAATGTCGCGTAAG
GCGCCGTCAGAGAACTGTAG

Product: AraC-type DNA-binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MCNVYVALDPETPSKMDFRGAVTDHPFDEIGISNIASLKQTIARTTSGIRRDTNAYCFLNLQVAGTCRIRQGNRDAITMP
GEFTVVDSSEPFLLDYTSDTWEQYAFKIPKHMFDSHVGHEFVARTVTDRTPIGKVVVDFLASIARNPENLRHSSINMTKT
IIDLVAMSLRASTPERDDDRRRTFRSPLRQSVLRYVELNFADPEISPAKVAAHFGISTRYLHKLLEEHGETLGQIILAKR
LDRCASELRKGTCLTISEAAFRWGFNDMSYFSRAFRRRFGVAPRDYRR

Sequences:

>Translated_288_residues
MCNVYVALDPETPSKMDFRGAVTDHPFDEIGISNIASLKQTIARTTSGIRRDTNAYCFLNLQVAGTCRIRQGNRDAITMP
GEFTVVDSSEPFLLDYTSDTWEQYAFKIPKHMFDSHVGHEFVARTVTDRTPIGKVVVDFLASIARNPENLRHSSINMTKT
IIDLVAMSLRASTPERDDDRRRTFRSPLRQSVLRYVELNFADPEISPAKVAAHFGISTRYLHKLLEEHGETLGQIILAKR
LDRCASELRKGTCLTISEAAFRWGFNDMSYFSRAFRRRFGVAPRDYRR
>Mature_288_residues
MCNVYVALDPETPSKMDFRGAVTDHPFDEIGISNIASLKQTIARTTSGIRRDTNAYCFLNLQVAGTCRIRQGNRDAITMP
GEFTVVDSSEPFLLDYTSDTWEQYAFKIPKHMFDSHVGHEFVARTVTDRTPIGKVVVDFLASIARNPENLRHSSINMTKT
IIDLVAMSLRASTPERDDDRRRTFRSPLRQSVLRYVELNFADPEISPAKVAAHFGISTRYLHKLLEEHGETLGQIILAKR
LDRCASELRKGTCLTISEAAFRWGFNDMSYFSRAFRRRFGVAPRDYRR

Specific function: Positive regulator of tynA/maoA and feaB/padA, the genes for 2-phenylethylamine catabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787649, Length=276, Percent_Identity=24.6376811594203, Blast_Score=97, Evalue=8e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 32849; Mature: 32849

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCNVYVALDPETPSKMDFRGAVTDHPFDEIGISNIASLKQTIARTTSGIRRDTNAYCFLN
CCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
LQVAGTCRIRQGNRDAITMPGEFTVVDSSEPFLLDYTSDTWEQYAFKIPKHMFDSHVGHE
EEEEEEEEEECCCCCEEECCCEEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHH
FVARTVTDRTPIGKVVVDFLASIARNPENLRHSSINMTKTIIDLVAMSLRASTPERDDDR
HHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHH
RRTFRSPLRQSVLRYVELNFADPEISPAKVAAHFGISTRYLHKLLEEHGETLGQIILAKR
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
LDRCASELRKGTCLTISEAAFRWGFNDMSYFSRAFRRRFGVAPRDYRR
HHHHHHHHHCCCEEEEHHHHHHCCCCHHHHHHHHHHHHHCCCCHHCCC
>Mature Secondary Structure
MCNVYVALDPETPSKMDFRGAVTDHPFDEIGISNIASLKQTIARTTSGIRRDTNAYCFLN
CCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
LQVAGTCRIRQGNRDAITMPGEFTVVDSSEPFLLDYTSDTWEQYAFKIPKHMFDSHVGHE
EEEEEEEEEECCCCCEEECCCEEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHH
FVARTVTDRTPIGKVVVDFLASIARNPENLRHSSINMTKTIIDLVAMSLRASTPERDDDR
HHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHH
RRTFRSPLRQSVLRYVELNFADPEISPAKVAAHFGISTRYLHKLLEEHGETLGQIILAKR
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
LDRCASELRKGTCLTISEAAFRWGFNDMSYFSRAFRRRFGVAPRDYRR
HHHHHHHHHCCCEEEEHHHHHHCCCCHHHHHHHHHHHHHCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8631685; 9043126; 9278503; 9109378 [H]