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The map label for this gene is fprA [H]

Identifier: 222102889

GI number: 222102889

Start: 566633

End: 567988

Strand: Reverse

Name: fprA [H]

Synonym: Avi_7630

Alternate gene names: 222102889

Gene position: 567988-566633 (Counterclockwise)

Preceding gene: 222102890

Following gene: 222102888

Centisome position: 89.9

GC content: 59.0

Gene sequence:

>1356_bases
ATGACCATCCCAATTGCCGCCGCCGCGAAGGCTGCTTCGCCTTTCCGCATCGCCATTGTCGGTGCAGGCCCGAGCGGCTT
CTACGCCGCCGAAGCTCTGTTGAGAGCACCGATCAACATTCAAGTCGACATGTTCGAGCGGCTGCCGGTGCCCTATGGCC
TGGTGCGGTTCGGCGTGGCGCCGGATCATCCGAAATTAAAACAGGTGACCGCCGTATTCGATCGTATTGCCAGCATGCCC
GGCTTCCGCTTTGTCGGCGGGATCGACGTGGGGATCGACGTGACGATAGACACGCTGTTTGATTGCTATCATGCCGTCAT
TCTTGCGACGGGTGCTGCGTTAGGTCGAAAGATGGGTATTCCTGGCGAGAGCCTGCCGGGAAGCCACCAGGCTAGCGATT
TCGTCGGCTGGTATAACGGTCACCCTGACTATCGCGATTGCTGCTTCGACCTCTCCGGTGAGCGTGCGGTGATTGTCGGA
CATGGAAATGTCGCTCTCGATATTGCCCGCATCCTGCTGAAGACGACCGACGAATTACGTCATAGCGACATCGCGGCCCA
TGCGCTGGAGGCCTTAGCCGAAAGCAAGATCCGCGAGGTGCAGGTCGTCGGGCGTCGTGGCCTGCTCGAAACGCGCTTTT
CGGCCAAGGAATTGCAGGAGTTCAGCATGCTCTCGGACTGCGACCCCGTCCTTGATCCGGACGATCCGGTGCCGGATGTC
GCCGCTTTGCCTGATGGCACTGACGCCGAGAAAAGGGCAGCTGTCAGCATGCTGGCATCGTTCTCGACGCAGATCTCGGA
TCGGAAGCGGCGTTGCGTGTTCCGGTTCCATCTGCAGCCGCACGCTATCGAGGGAAGAGATCGGGTTGAGCGGATGGTAT
TCAGCCGAGGCTCCAGCCTATCCGGCGATAAGTCTATGCCGGTTTCCATCGACTGCGGTCTCGTATTTTCCAGCATCGGC
AGACGGTCTGCGCCCGTTCCGGGCGTTGCCTATGACGAGGCGAGGGGCGTTCATGCCAATGTAGCAGGACGAGGCCCTCA
TCAAGCGACCTATGTTTGTGGGTGGAGCAAGCGCGGCCCACAAGGCACGATTGGTACCAACAGGGCATGCGCAGTCGAAA
CCGTGCAGCATGTTCTTGCCGATCTTTCCAGCAATGGTCATCGCGTGCTCGCGGATGCCGATGCCTTGATCGCAAGGCTG
GCCGGTAAGCATGGTGTCCACATCGATTTCGCGTCGTGGCAGGCTATCGATGCTGCGGAATTGGAGCAAGGCCGCCTTGC
TGGAAAGCCCCGAGAAAAATTTTTGTCTGTCGACCAGATGATTTCTGTCGTCACAAAGAGACGCACAGCATGCTAA

Upstream 100 bases:

>100_bases
GGATTGAAATCAATCGTCGCCGCGCTGCAGAAACGCCGGTGGTCGCCAGTCGGCTACCGCCCTTGCCAGGGGCTGAGGAG
CGACGGCAGGCTCTGACATC

Downstream 100 bases:

>100_bases
CCCCGGGGACTGCCTTGCCTTCTTCGTGTGGTCTGATCGACCGGTTCGGTCGCCGCGTGACTTATCTACGTCTTTCAGTG
ACCGATCGTTGCGATCTACG

Product: hypothetical protein

Products: NA

Alternate protein names: NFR [H]

Number of amino acids: Translated: 451; Mature: 450

Protein sequence:

>451_residues
MTIPIAAAAKAASPFRIAIVGAGPSGFYAAEALLRAPINIQVDMFERLPVPYGLVRFGVAPDHPKLKQVTAVFDRIASMP
GFRFVGGIDVGIDVTIDTLFDCYHAVILATGAALGRKMGIPGESLPGSHQASDFVGWYNGHPDYRDCCFDLSGERAVIVG
HGNVALDIARILLKTTDELRHSDIAAHALEALAESKIREVQVVGRRGLLETRFSAKELQEFSMLSDCDPVLDPDDPVPDV
AALPDGTDAEKRAAVSMLASFSTQISDRKRRCVFRFHLQPHAIEGRDRVERMVFSRGSSLSGDKSMPVSIDCGLVFSSIG
RRSAPVPGVAYDEARGVHANVAGRGPHQATYVCGWSKRGPQGTIGTNRACAVETVQHVLADLSSNGHRVLADADALIARL
AGKHGVHIDFASWQAIDAAELEQGRLAGKPREKFLSVDQMISVVTKRRTAC

Sequences:

>Translated_451_residues
MTIPIAAAAKAASPFRIAIVGAGPSGFYAAEALLRAPINIQVDMFERLPVPYGLVRFGVAPDHPKLKQVTAVFDRIASMP
GFRFVGGIDVGIDVTIDTLFDCYHAVILATGAALGRKMGIPGESLPGSHQASDFVGWYNGHPDYRDCCFDLSGERAVIVG
HGNVALDIARILLKTTDELRHSDIAAHALEALAESKIREVQVVGRRGLLETRFSAKELQEFSMLSDCDPVLDPDDPVPDV
AALPDGTDAEKRAAVSMLASFSTQISDRKRRCVFRFHLQPHAIEGRDRVERMVFSRGSSLSGDKSMPVSIDCGLVFSSIG
RRSAPVPGVAYDEARGVHANVAGRGPHQATYVCGWSKRGPQGTIGTNRACAVETVQHVLADLSSNGHRVLADADALIARL
AGKHGVHIDFASWQAIDAAELEQGRLAGKPREKFLSVDQMISVVTKRRTAC
>Mature_450_residues
TIPIAAAAKAASPFRIAIVGAGPSGFYAAEALLRAPINIQVDMFERLPVPYGLVRFGVAPDHPKLKQVTAVFDRIASMPG
FRFVGGIDVGIDVTIDTLFDCYHAVILATGAALGRKMGIPGESLPGSHQASDFVGWYNGHPDYRDCCFDLSGERAVIVGH
GNVALDIARILLKTTDELRHSDIAAHALEALAESKIREVQVVGRRGLLETRFSAKELQEFSMLSDCDPVLDPDDPVPDVA
ALPDGTDAEKRAAVSMLASFSTQISDRKRRCVFRFHLQPHAIEGRDRVERMVFSRGSSLSGDKSMPVSIDCGLVFSSIGR
RSAPVPGVAYDEARGVHANVAGRGPHQATYVCGWSKRGPQGTIGTNRACAVETVQHVLADLSSNGHRVLADADALIARLA
GKHGVHIDFASWQAIDAAELEQGRLAGKPREKFLSVDQMISVVTKRRTAC

Specific function: May serve as electron transfer protein and supply electrons to P450 systems [H]

COG id: COG0493

COG function: function code ER; NADPH-dependent glutamate synthase beta chain and related oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ferredoxin--NADP reductase type 1 family [H]

Homologues:

Organism=Homo sapiens, GI111118981, Length=454, Percent_Identity=38.5462555066079, Blast_Score=273, Evalue=3e-73,
Organism=Homo sapiens, GI111118983, Length=460, Percent_Identity=38.0434782608696, Blast_Score=267, Evalue=1e-71,
Organism=Escherichia coli, GI1788811, Length=164, Percent_Identity=32.3170731707317, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87082180, Length=167, Percent_Identity=30.5389221556886, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1789606, Length=208, Percent_Identity=29.8076923076923, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17543860, Length=444, Percent_Identity=31.981981981982, Blast_Score=218, Evalue=7e-57,
Organism=Saccharomyces cerevisiae, GI6320584, Length=487, Percent_Identity=30.5954825462012, Blast_Score=202, Evalue=8e-53,
Organism=Drosophila melanogaster, GI17137178, Length=448, Percent_Identity=38.6160714285714, Blast_Score=253, Evalue=2e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR021163
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07992 Pyr_redox_2 [H]

EC number: =1.18.1.2 [H]

Molecular weight: Translated: 48494; Mature: 48363

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIPIAAAAKAASPFRIAIVGAGPSGFYAAEALLRAPINIQVDMFERLPVPYGLVRFGVA
CCCCCCHHHCCCCCEEEEEEECCCCCHHHHHHHHHCCCCEEEEHHHHCCCCHHHHEECCC
PDHPKLKQVTAVFDRIASMPGFRFVGGIDVGIDVTIDTLFDCYHAVILATGAALGRKMGI
CCCCHHHHHHHHHHHHHCCCCCEEECCEECCEEEHHHHHHHHHHHHHHHHHHHHHHCCCC
PGESLPGSHQASDFVGWYNGHPDYRDCCFDLSGERAVIVGHGNVALDIARILLKTTDELR
CCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHH
HSDIAAHALEALAESKIREVQVVGRRGLLETRFSAKELQEFSMLSDCDPVLDPDDPVPDV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCC
AALPDGTDAEKRAAVSMLASFSTQISDRKRRCVFRFHLQPHAIEGRDRVERMVFSRGSSL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCCHHHHHHHHHHCCCCC
SGDKSMPVSIDCGLVFSSIGRRSAPVPGVAYDEARGVHANVAGRGPHQATYVCGWSKRGP
CCCCCCCEEEEHHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCCCCCCEEEEEECCCCCC
QGTIGTNRACAVETVQHVLADLSSNGHRVLADADALIARLAGKHGVHIDFASWQAIDAAE
CCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCCCCCEEEECCCCCCCHHH
LEQGRLAGKPREKFLSVDQMISVVTKRRTAC
HHCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TIPIAAAAKAASPFRIAIVGAGPSGFYAAEALLRAPINIQVDMFERLPVPYGLVRFGVA
CCCCCHHHCCCCCEEEEEEECCCCCHHHHHHHHHCCCCEEEEHHHHCCCCHHHHEECCC
PDHPKLKQVTAVFDRIASMPGFRFVGGIDVGIDVTIDTLFDCYHAVILATGAALGRKMGI
CCCCHHHHHHHHHHHHHCCCCCEEECCEECCEEEHHHHHHHHHHHHHHHHHHHHHHCCCC
PGESLPGSHQASDFVGWYNGHPDYRDCCFDLSGERAVIVGHGNVALDIARILLKTTDELR
CCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHH
HSDIAAHALEALAESKIREVQVVGRRGLLETRFSAKELQEFSMLSDCDPVLDPDDPVPDV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCC
AALPDGTDAEKRAAVSMLASFSTQISDRKRRCVFRFHLQPHAIEGRDRVERMVFSRGSSL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCCHHHHHHHHHHCCCCC
SGDKSMPVSIDCGLVFSSIGRRSAPVPGVAYDEARGVHANVAGRGPHQATYVCGWSKRGP
CCCCCCCEEEEHHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCCCCCCEEEEEECCCCCC
QGTIGTNRACAVETVQHVLADLSSNGHRVLADADALIARLAGKHGVHIDFASWQAIDAAE
CCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCCCCCEEEECCCCCCCHHH
LEQGRLAGKPREKFLSVDQMISVVTKRRTAC
HHCCCCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036; 12071965; 12614197; 12102623 [H]