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The map label for this gene is yisS [H]

Identifier: 222102765

GI number: 222102765

Start: 422937

End: 424013

Strand: Direct

Name: yisS [H]

Synonym: Avi_7457

Alternate gene names: 222102765

Gene position: 422937-424013 (Clockwise)

Preceding gene: 222102762

Following gene: 222102771

Centisome position: 66.94

GC content: 54.32

Gene sequence:

>1077_bases
ATGGTGAAGCTTGGTCTTGTGGGTCTTGGAGAAGTAGCGCAGTTGATCCATCTGCCGATTTTGCAAAGACTGACCGAAAT
GTTCACACTTGCGGGCGCTTATGATCCGTCCCCCAGCGTGGCCCAGTCGATCTCGACACGGTGGAGCATTGAGCGCGTAT
TTGACAGTGTCGATGCGATGATTGCGTCACCGGATATTGATGCAATTCTGATCATGAGCCCGGATCAATACCATGGCCGT
CATGCCCGTGCGGCCCTGAAAGCTGATAAGCATGTTTTGATTGAAAAGCCCTGCTGTTTGACGATGGAAGACCTCGCTGC
ACTCAGTGGTGTGGTGGAGCAGACAGATCGCATTGCCATGGTTGGCTATATGCGTCGATTTGCGCCCGCCTTTCTGGAGG
CGAAAAGGCGGTTGCCAGCCTTTGCCGACATTACCTACGTTCGTGTCCGGGATGTCATCTGCGAAGGCCCCTGGTATTTT
CGCCAAACAGATACGGTTGTCACGCCCAAGGACGATATTCCGGCAAGCCTTATCGAGGAAAGCCGTCAGTTGCGTGGTAC
GATGATGGACAGCGTGCTTGGCCCGAATGCACCCGCTGAACTTCAGACGGCGTATTCTGTGCTGACAGGGCTTTCGTCTC
ATTCCCTCTCGGCCATGCGGGATCTGCTGGGCAGTCCCAAGCGCGTGATTGCCGCCGAGATTAAACAGGGCGGCAGCCAG
ATCACGGCCCTCTTTGACTACGGTCATTTTACCGCAATTTATGAATGCATGATTGGCGATGTGGTGCGCTTTGAAGCCGG
TTTCGAGATCAACTCTCGCTACAATCGTCTGGCCTTTGAATATCCAACCCCTTACATCCGCAATCTGCCGATGGTGCTGG
ATATTCAAAATTCCACCGATCACGATAACAGCCTCACCCGGCTTGGCCCCTTTCATCAAGACCCCTTTGATGTCGAGTTG
CGAGCATTCCATGCGGCGGTCACGCAAGGCGGCGAGAACCGAACGCCACCATCAGAGTCCATGGCTGATCTCGATCTGTT
TGCCGCTATTATCTCTGCGGCACGCAAGACGGACTGA

Upstream 100 bases:

>100_bases
ATTTCGTGCAAAACATCCCTTGATATAATCATTATTGTGTATTTAATTCGGCCTGAAATATCTATCGCATCTTGAAAGCT
GGTCGAAGGCGGGAAATCCT

Downstream 100 bases:

>100_bases
TGATTGCAACGACTGGTATCGCGGAAATCGCGGGAATGCACGGTGCCAGATCGCACATCTGTGTCAATTAAAGTTCAGTC
GTCTTATCTTTACCGTCAAC

Product: hypothetical protein

Products: 2,4,6/3,5-pentahydroxycyclohexanone; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MVKLGLVGLGEVAQLIHLPILQRLTEMFTLAGAYDPSPSVAQSISTRWSIERVFDSVDAMIASPDIDAILIMSPDQYHGR
HARAALKADKHVLIEKPCCLTMEDLAALSGVVEQTDRIAMVGYMRRFAPAFLEAKRRLPAFADITYVRVRDVICEGPWYF
RQTDTVVTPKDDIPASLIEESRQLRGTMMDSVLGPNAPAELQTAYSVLTGLSSHSLSAMRDLLGSPKRVIAAEIKQGGSQ
ITALFDYGHFTAIYECMIGDVVRFEAGFEINSRYNRLAFEYPTPYIRNLPMVLDIQNSTDHDNSLTRLGPFHQDPFDVEL
RAFHAAVTQGGENRTPPSESMADLDLFAAIISAARKTD

Sequences:

>Translated_358_residues
MVKLGLVGLGEVAQLIHLPILQRLTEMFTLAGAYDPSPSVAQSISTRWSIERVFDSVDAMIASPDIDAILIMSPDQYHGR
HARAALKADKHVLIEKPCCLTMEDLAALSGVVEQTDRIAMVGYMRRFAPAFLEAKRRLPAFADITYVRVRDVICEGPWYF
RQTDTVVTPKDDIPASLIEESRQLRGTMMDSVLGPNAPAELQTAYSVLTGLSSHSLSAMRDLLGSPKRVIAAEIKQGGSQ
ITALFDYGHFTAIYECMIGDVVRFEAGFEINSRYNRLAFEYPTPYIRNLPMVLDIQNSTDHDNSLTRLGPFHQDPFDVEL
RAFHAAVTQGGENRTPPSESMADLDLFAAIISAARKTD
>Mature_358_residues
MVKLGLVGLGEVAQLIHLPILQRLTEMFTLAGAYDPSPSVAQSISTRWSIERVFDSVDAMIASPDIDAILIMSPDQYHGR
HARAALKADKHVLIEKPCCLTMEDLAALSGVVEQTDRIAMVGYMRRFAPAFLEAKRRLPAFADITYVRVRDVICEGPWYF
RQTDTVVTPKDDIPASLIEESRQLRGTMMDSVLGPNAPAELQTAYSVLTGLSSHSLSAMRDLLGSPKRVIAAEIKQGGSQ
ITALFDYGHFTAIYECMIGDVVRFEAGFEINSRYNRLAFEYPTPYIRNLPMVLDIQNSTDHDNSLTRLGPFHQDPFDVEL
RAFHAAVTQGGENRTPPSESMADLDLFAAIISAARKTD

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI1787307, Length=143, Percent_Identity=32.8671328671329, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: 1.1.1.18

Molecular weight: Translated: 39638; Mature: 39638

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKLGLVGLGEVAQLIHLPILQRLTEMFTLAGAYDPSPSVAQSISTRWSIERVFDSVDAM
CEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IASPDIDAILIMSPDQYHGRHARAALKADKHVLIEKPCCLTMEDLAALSGVVEQTDRIAM
HCCCCCCEEEEECCCHHCCHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
VGYMRRFAPAFLEAKRRLPAFADITYVRVRDVICEGPWYFRQTDTVVTPKDDIPASLIEE
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEECCCEEECCCCCCCHHHHHH
SRQLRGTMMDSVLGPNAPAELQTAYSVLTGLSSHSLSAMRDLLGSPKRVIAAEIKQGGSQ
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCE
ITALFDYGHFTAIYECMIGDVVRFEAGFEINSRYNRLAFEYPTPYIRNLPMVLDIQNSTD
EEEEEECHHHHHHHHHHHHHHHHEECCCEECCCCCEEEEECCCHHHHCCCEEEEECCCCC
HDNSLTRLGPFHQDPFDVELRAFHAAVTQGGENRTPPSESMADLDLFAAIISAARKTD
CCCCHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVKLGLVGLGEVAQLIHLPILQRLTEMFTLAGAYDPSPSVAQSISTRWSIERVFDSVDAM
CEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IASPDIDAILIMSPDQYHGRHARAALKADKHVLIEKPCCLTMEDLAALSGVVEQTDRIAM
HCCCCCCEEEEECCCHHCCHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
VGYMRRFAPAFLEAKRRLPAFADITYVRVRDVICEGPWYFRQTDTVVTPKDDIPASLIEE
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEECCCEEECCCCCCCHHHHHH
SRQLRGTMMDSVLGPNAPAELQTAYSVLTGLSSHSLSAMRDLLGSPKRVIAAEIKQGGSQ
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCE
ITALFDYGHFTAIYECMIGDVVRFEAGFEINSRYNRLAFEYPTPYIRNLPMVLDIQNSTD
EEEEEECHHHHHHHHHHHHHHHHEECCCEECCCCCEEEEECCCHHHHCCCEEEEECCCCC
HDNSLTRLGPFHQDPFDVELRAFHAAVTQGGENRTPPSESMADLDLFAAIISAARKTD
CCCCHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: myo-inositol; NAD+

Specific reaction: myo-inositol + NAD+ = 2,4,6/3,5-pentahydroxycyclohexanone + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353932; 9384377; 8407808 [H]