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The map label for this gene is mlc [C]

Identifier: 222102763

GI number: 222102763

Start: 420492

End: 421757

Strand: Reverse

Name: mlc [C]

Synonym: Avi_7454

Alternate gene names: 222102763

Gene position: 421757-420492 (Counterclockwise)

Preceding gene: 222102764

Following gene: 222102758

Centisome position: 66.76

GC content: 58.37

Gene sequence:

>1266_bases
GTGACACTTCTGGATCGGTTTGATGGAGGCTTTGCCCGCGACGGTGAGGACATTATTGCGGGCAGCCGGATTGAAGATGC
CCGCATTCACAATCGTCGTCTGGTGTTTGAAACCATTTTTCAACGCGGCCCCATCAGTCGGGTGGAGATTTCAGCCATTG
TCGGGCTGAAACCCCAAACCATTTCGTCCATCACCCGCGAACTGCTCGAGCAGGAATTGATCGTCGAGGCCGGACGGTCC
TCCGGTCTTCGCGGTCAGCCGCAAATCTATCTGGAGGCCAATGCCGAAGCGGGCTTTTCAATCGGGGTTCATCTGGATCA
GAACCAGTGTCATATTCTGGTGTTTGACCTGAAACGGCAAGAACGCGCCCGCAAATCGATGCGGTGTGATACGGCAAACC
CCGATGTGACCGTGCGGATGCTGGCGCAAACCATAACAACATTGCTGCACGACAATGCCCTGCCTGCTGAACGGATCTGG
GGCCTTGGTCTGGTGCTGCCCACATTCGGCTCCGATGTCTACGATTTCGATTTTTCCATGCGGCATTGGGAGGCCTGGCG
CGATGCATCCTTTGCCGAAGACCTGCAACGCCTGACCGGCTTTGCCGTTCTGGTGGAAAATGACGGAACAGCGGCAGCCA
TTGGCGAGCGCCTTCACCGCCACGATGCACAGGAGGCGTCGTTTGCCTATTTCTACATCGGCCATGGTGCCGGTGCCGGG
CTAATTATTGATGGCTATCCCTTCAAGGGTGTTGGCGGAAATGCCGGCGAAATCGGGCTGTTGCCAATCCTTGGCCTTGG
CGCCAATCCGGTCTGGCCGGACAATCCCAGCAGCGCTGTTCAGGGCGGTGTTCTTTCTATTGGCGGGCTGGCAGCCGCTT
GCGGTCTATCAGAGCAGTCCATGGATGAGCAGAGCATCTTGAGCCTGCTGGAGCGGCGTGATCATCGGTTGATGGATTGG
CTGGCGTCTGCGGCCAGTGTACTGCGTGATGTCTGCGCAGTCATTGAAGTGATGTTCGATCCCGGCTTTATTGCCGTGGG
CGGTGCGTTGCCACGGGCGCTGGTGGAACGGCTGGTGGATCGCGCCTATCCGCTGCGCCCCACGCCATCGGCTCGGCGTG
ACCGGGCCTTGCCTCGGCTTTTGCCTGCAACGCTGATTGAGGATGCGGCGGTGACAGGGGCCGCGATGTTGCCGATTTTT
GTCACCACCAGCCATAATTTCCGCCATCTCTATTTCCGGCAGATTCTCGCAGACGACCGGTCATGA

Upstream 100 bases:

>100_bases
CCTTTTCCGATTGCGTGCCACAACCGGCAGGTCTTGCGTGAGCTTGGGATTTAACATCCATACCGAGAGTGGCGTGCGAC
AATAGGACGAAGGAACAGCC

Downstream 100 bases:

>100_bases
TTATGCAGGCCCGGCATGATGCACGGCCTTGTTATCGCGAAACACCGTGTAGCGGGCGACAACCGGGGTATAGAACACCC
CTTCCTTGATGTCGGCGTCT

Product: transcriptional regulator ROK family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 420

Protein sequence:

>421_residues
MTLLDRFDGGFARDGEDIIAGSRIEDARIHNRRLVFETIFQRGPISRVEISAIVGLKPQTISSITRELLEQELIVEAGRS
SGLRGQPQIYLEANAEAGFSIGVHLDQNQCHILVFDLKRQERARKSMRCDTANPDVTVRMLAQTITTLLHDNALPAERIW
GLGLVLPTFGSDVYDFDFSMRHWEAWRDASFAEDLQRLTGFAVLVENDGTAAAIGERLHRHDAQEASFAYFYIGHGAGAG
LIIDGYPFKGVGGNAGEIGLLPILGLGANPVWPDNPSSAVQGGVLSIGGLAAACGLSEQSMDEQSILSLLERRDHRLMDW
LASAASVLRDVCAVIEVMFDPGFIAVGGALPRALVERLVDRAYPLRPTPSARRDRALPRLLPATLIEDAAVTGAAMLPIF
VTTSHNFRHLYFRQILADDRS

Sequences:

>Translated_421_residues
MTLLDRFDGGFARDGEDIIAGSRIEDARIHNRRLVFETIFQRGPISRVEISAIVGLKPQTISSITRELLEQELIVEAGRS
SGLRGQPQIYLEANAEAGFSIGVHLDQNQCHILVFDLKRQERARKSMRCDTANPDVTVRMLAQTITTLLHDNALPAERIW
GLGLVLPTFGSDVYDFDFSMRHWEAWRDASFAEDLQRLTGFAVLVENDGTAAAIGERLHRHDAQEASFAYFYIGHGAGAG
LIIDGYPFKGVGGNAGEIGLLPILGLGANPVWPDNPSSAVQGGVLSIGGLAAACGLSEQSMDEQSILSLLERRDHRLMDW
LASAASVLRDVCAVIEVMFDPGFIAVGGALPRALVERLVDRAYPLRPTPSARRDRALPRLLPATLIEDAAVTGAAMLPIF
VTTSHNFRHLYFRQILADDRS
>Mature_420_residues
TLLDRFDGGFARDGEDIIAGSRIEDARIHNRRLVFETIFQRGPISRVEISAIVGLKPQTISSITRELLEQELIVEAGRSS
GLRGQPQIYLEANAEAGFSIGVHLDQNQCHILVFDLKRQERARKSMRCDTANPDVTVRMLAQTITTLLHDNALPAERIWG
LGLVLPTFGSDVYDFDFSMRHWEAWRDASFAEDLQRLTGFAVLVENDGTAAAIGERLHRHDAQEASFAYFYIGHGAGAGL
IIDGYPFKGVGGNAGEIGLLPILGLGANPVWPDNPSSAVQGGVLSIGGLAAACGLSEQSMDEQSILSLLERRDHRLMDWL
ASAASVLRDVCAVIEVMFDPGFIAVGGALPRALVERLVDRAYPLRPTPSARRDRALPRLLPATLIEDAAVTGAAMLPIFV
TTSHNFRHLYFRQILADDRS

Specific function: May Be A Regulator In Specific Sugar Metabolism. May Influence The Rate Of Glucose Uptake Or Glycolysis In Cells In The Rich Medium. [C]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Escherichia coli, GI1787878, Length=368, Percent_Identity=23.3695652173913, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1786891, Length=245, Percent_Identity=26.1224489795918, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 46091; Mature: 45960

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLLDRFDGGFARDGEDIIAGSRIEDARIHNRRLVFETIFQRGPISRVEISAIVGLKPQT
CCCCCCCCCCCCCCCCHHHCCCCCCHHHHHCCHHHHHHHHCCCCCCCEEEEEEECCCCHH
ISSITRELLEQELIVEAGRSSGLRGQPQIYLEANAEAGFSIGVHLDQNQCHILVFDLKRQ
HHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCEEEEEEECCCCCEEEEEECHHH
ERARKSMRCDTANPDVTVRMLAQTITTLLHDNALPAERIWGLGLVLPTFGSDVYDFDFSM
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHCCCEECCCCCCCEEECCCCH
RHWEAWRDASFAEDLQRLTGFAVLVENDGTAAAIGERLHRHDAQEASFAYFYIGHGAGAG
HHHHHHCCCHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHCCCCCCCEEEEEEEECCCCC
LIIDGYPFKGVGGNAGEIGLLPILGLGANPVWPDNPSSAVQGGVLSIGGLAAACGLSEQS
EEEECCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHCCCCEEHHHHHHHHCCCHHC
MDEQSILSLLERRDHRLMDWLASAASVLRDVCAVIEVMFDPGFIAVGGALPRALVERLVD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHH
RAYPLRPTPSARRDRALPRLLPATLIEDAAVTGAAMLPIFVTTSHNFRHLYFRQILADDR
HCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHCCC
S
C
>Mature Secondary Structure 
TLLDRFDGGFARDGEDIIAGSRIEDARIHNRRLVFETIFQRGPISRVEISAIVGLKPQT
CCCCCCCCCCCCCCCHHHCCCCCCHHHHHCCHHHHHHHHCCCCCCCEEEEEEECCCCHH
ISSITRELLEQELIVEAGRSSGLRGQPQIYLEANAEAGFSIGVHLDQNQCHILVFDLKRQ
HHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCEEEEEEECCCCCEEEEEECHHH
ERARKSMRCDTANPDVTVRMLAQTITTLLHDNALPAERIWGLGLVLPTFGSDVYDFDFSM
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHCCCEECCCCCCCEEECCCCH
RHWEAWRDASFAEDLQRLTGFAVLVENDGTAAAIGERLHRHDAQEASFAYFYIGHGAGAG
HHHHHHCCCHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHCCCCCCCEEEEEEEECCCCC
LIIDGYPFKGVGGNAGEIGLLPILGLGANPVWPDNPSSAVQGGVLSIGGLAAACGLSEQS
EEEECCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHCCCCEEHHHHHHHHCCCHHC
MDEQSILSLLERRDHRLMDWLASAASVLRDVCAVIEVMFDPGFIAVGGALPRALVERLVD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHH
RAYPLRPTPSARRDRALPRLLPATLIEDAAVTGAAMLPIFVTTSHNFRHLYFRQILADDR
HCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHCCC
S
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]