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The map label for this gene is xylH [H]

Identifier: 222102702

GI number: 222102702

Start: 351152

End: 352411

Strand: Reverse

Name: xylH [H]

Synonym: Avi_7376

Alternate gene names: 222102702

Gene position: 352411-351152 (Counterclockwise)

Preceding gene: 222102703

Following gene: 222102701

Centisome position: 55.78

GC content: 56.98

Gene sequence:

>1260_bases
ATGAGCAATATTTCAAACCCTGAACCCAAGTCCTCCCAAGCCTTGGACCGCAGCGATGAGCGCGTCACCCACGATGATGG
TGTGCTGGCCATGCTGCGCAGTTTTATCAATCGGATCAAATCGGGCGATCTGGGCATGTTGCCAGTTGCCATTGGGCTGA
TTGTGATTTCCACCGTGTTCAGCATTCTCAATCCGGTTTTTCTGGCACCCAACAATCTGGTCAATCTGCTGTTTGATTGC
GCAACGGTGGGCATTATTTCGCTGGGCATTGTCTGCGTGCTGCTGTTGGGTGAGATTGATCTCTCGGTTGGCTCCATGAG
TGGTCTGGCCTCGGCTATCATTGGCGTGTTGTGGGTCAATTCCGGCCTTCCGGTGGTTGTTGCGATTTTTGCAGCGCTGG
TCACAGGTGCTGCCGTGGGGGCGCTTTACGCTGTGATGTATAATCGCATGGGCATGCCAAGCTTTGTCGCCACGCTGTCT
GGCCTGCTGGCCTTGCTGGGCATGCAGCTCTACATTCTCGGCCCAACGGGCAGTATCAATCTGCCCTATGCCTCACCTCT
GGTGCGGTTTGGCCAGATTTTGGTGATGCCGCATTGGCTGTCCTTCACGCTGGCTTTGGTGCCCGGCATTGTGATGGTTG
TGTTTGGCTTAAGCGTGCGCAAGCGCCGCCAAGCGGTCAACCTGTCCTCAAAGCCCTTGAGTGGCTTGCTCATCAAAGCC
GCCATCCTCACGCTTGGCTTCGAATTTGCAGTCTATTATCTCAATCTCGGACGCGGCGTGCCCTGGATGTTTGCGCTGTT
CGTGGCGCTGGTGGTGGTGGTCAATTACCTGCTGACCAAGACACAATGGGGCCGCTCAATGTTTGCCGTGGGTGGCAATC
GTGAAGCCGCACGCCGCGCTGGTATCAATGTCCGCCGCATTTACATGAGCGCCTTTATGCTGTGCTCCACCCTTGCAGCG
CTTGGTGGCGTGTTGTCGGCATCGCGCCTTGCATCCTCCAGCCAGCAGGCTGGCACGGGTGATGTGAATTTGAACGCCAT
TGCCGCCGCCGTGATTGGTGGCACCAGCCTGTTTGGCGGGCGTGGCAGTGCCTATTCGGCCCTGCTTGGGATCATCGTCA
TTCAGGCGATTTCCAATGGTTTGACGCTTCTCAACCTCAGTTCATCACTGCGCTACATGATCACCGGGGCAGTGCTTGCC
ATTGCCGTGATTGTGGATTCGCTCGCGCGCCGCTCCCGTGTCAGTCACGGCCGCGCCTAA

Upstream 100 bases:

>100_bases
CCTCCATCACCGGGGCCACGGAAAATTCCGTCTCACGCCGCCTGACCCGCAAGACAAATAGCCAAGAAACCAGCGCCCCA
GACACGAGGGGGAGACCCGC

Downstream 100 bases:

>100_bases
CAAGATTTACAAGGAGAATTGTATCATGACAGATATCATGAAAGGCAAAGTCGCCGCCATCACCGGTGCTGCATCGGGCA
TCGGTCTCGCTTGCGCCAAA

Product: ABC transporter membrane spanning protein (xylose)

Products: ADP; phosphate; xylose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 418

Protein sequence:

>419_residues
MSNISNPEPKSSQALDRSDERVTHDDGVLAMLRSFINRIKSGDLGMLPVAIGLIVISTVFSILNPVFLAPNNLVNLLFDC
ATVGIISLGIVCVLLLGEIDLSVGSMSGLASAIIGVLWVNSGLPVVVAIFAALVTGAAVGALYAVMYNRMGMPSFVATLS
GLLALLGMQLYILGPTGSINLPYASPLVRFGQILVMPHWLSFTLALVPGIVMVVFGLSVRKRRQAVNLSSKPLSGLLIKA
AILTLGFEFAVYYLNLGRGVPWMFALFVALVVVVNYLLTKTQWGRSMFAVGGNREAARRAGINVRRIYMSAFMLCSTLAA
LGGVLSASRLASSSQQAGTGDVNLNAIAAAVIGGTSLFGGRGSAYSALLGIIVIQAISNGLTLLNLSSSLRYMITGAVLA
IAVIVDSLARRSRVSHGRA

Sequences:

>Translated_419_residues
MSNISNPEPKSSQALDRSDERVTHDDGVLAMLRSFINRIKSGDLGMLPVAIGLIVISTVFSILNPVFLAPNNLVNLLFDC
ATVGIISLGIVCVLLLGEIDLSVGSMSGLASAIIGVLWVNSGLPVVVAIFAALVTGAAVGALYAVMYNRMGMPSFVATLS
GLLALLGMQLYILGPTGSINLPYASPLVRFGQILVMPHWLSFTLALVPGIVMVVFGLSVRKRRQAVNLSSKPLSGLLIKA
AILTLGFEFAVYYLNLGRGVPWMFALFVALVVVVNYLLTKTQWGRSMFAVGGNREAARRAGINVRRIYMSAFMLCSTLAA
LGGVLSASRLASSSQQAGTGDVNLNAIAAAVIGGTSLFGGRGSAYSALLGIIVIQAISNGLTLLNLSSSLRYMITGAVLA
IAVIVDSLARRSRVSHGRA
>Mature_418_residues
SNISNPEPKSSQALDRSDERVTHDDGVLAMLRSFINRIKSGDLGMLPVAIGLIVISTVFSILNPVFLAPNNLVNLLFDCA
TVGIISLGIVCVLLLGEIDLSVGSMSGLASAIIGVLWVNSGLPVVVAIFAALVTGAAVGALYAVMYNRMGMPSFVATLSG
LLALLGMQLYILGPTGSINLPYASPLVRFGQILVMPHWLSFTLALVPGIVMVVFGLSVRKRRQAVNLSSKPLSGLLIKAA
ILTLGFEFAVYYLNLGRGVPWMFALFVALVVVVNYLLTKTQWGRSMFAVGGNREAARRAGINVRRIYMSAFMLCSTLAAL
GGVLSASRLASSSQQAGTGDVNLNAIAAAVIGGTSLFGGRGSAYSALLGIIVIQAISNGLTLLNLSSSLRYMITGAVLAI
AVIVDSLARRSRVSHGRA

Specific function: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4214

COG function: function code G; ABC-type xylose transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789992, Length=350, Percent_Identity=33.4285714285714, Blast_Score=158, Evalue=5e-40,
Organism=Escherichia coli, GI1788896, Length=151, Percent_Identity=45.0331125827815, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1790191, Length=132, Percent_Identity=43.1818181818182, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1790524, Length=167, Percent_Identity=35.3293413173653, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI145693152, Length=165, Percent_Identity=36.969696969697, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1788471, Length=150, Percent_Identity=38.6666666666667, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1787793, Length=145, Percent_Identity=37.9310344827586, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI87082395, Length=125, Percent_Identity=36, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 43972; Mature: 43841

Theoretical pI: Translated: 10.70; Mature: 10.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNISNPEPKSSQALDRSDERVTHDDGVLAMLRSFINRIKSGDLGMLPVAIGLIVISTVF
CCCCCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
SILNPVFLAPNNLVNLLFDCATVGIISLGIVCVLLLGEIDLSVGSMSGLASAIIGVLWVN
HHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHC
SGLPVVVAIFAALVTGAAVGALYAVMYNRMGMPSFVATLSGLLALLGMQLYILGPTGSIN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEEECCCCCCC
LPYASPLVRFGQILVMPHWLSFTLALVPGIVMVVFGLSVRKRRQAVNLSSKPLSGLLIKA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
AILTLGFEFAVYYLNLGRGVPWMFALFVALVVVVNYLLTKTQWGRSMFAVGGNREAARRA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHC
GINVRRIYMSAFMLCSTLAALGGVLSASRLASSSQQAGTGDVNLNAIAAAVIGGTSLFGG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCC
RGSAYSALLGIIVIQAISNGLTLLNLSSSLRYMITGAVLAIAVIVDSLARRSRVSHGRA
CCHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SNISNPEPKSSQALDRSDERVTHDDGVLAMLRSFINRIKSGDLGMLPVAIGLIVISTVF
CCCCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
SILNPVFLAPNNLVNLLFDCATVGIISLGIVCVLLLGEIDLSVGSMSGLASAIIGVLWVN
HHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHC
SGLPVVVAIFAALVTGAAVGALYAVMYNRMGMPSFVATLSGLLALLGMQLYILGPTGSIN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEEECCCCCCC
LPYASPLVRFGQILVMPHWLSFTLALVPGIVMVVFGLSVRKRRQAVNLSSKPLSGLLIKA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
AILTLGFEFAVYYLNLGRGVPWMFALFVALVVVVNYLLTKTQWGRSMFAVGGNREAARRA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHC
GINVRRIYMSAFMLCSTLAALGGVLSASRLASSSQQAGTGDVNLNAIAAAVIGGTSLFGG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCC
RGSAYSALLGIIVIQAISNGLTLLNLSSSLRYMITGAVLAIAVIVDSLARRSRVSHGRA
CCHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; xylose [Periplasm]; H2O [C]

Specific reaction: ATP + xylose [Periplasm] + H2O = ADP + phosphate + xylose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]