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The map label for this gene is uxuR [H]

Identifier: 222102682

GI number: 222102682

Start: 330153

End: 331007

Strand: Reverse

Name: uxuR [H]

Synonym: Avi_7351

Alternate gene names: 222102682

Gene position: 331007-330153 (Counterclockwise)

Preceding gene: 222102683

Following gene: 222102679

Centisome position: 52.39

GC content: 60.35

Gene sequence:

>855_bases
ATGGCCTTTTACAGAGCAGTTGAATTTGCGTACGATTCATCATACATATTCCACTTAGAGAGACGAAAACGGCTCTGCCT
TCTGCGGCAGGGCATGAAAGTGGTGGATGGTGTGACCGGTCAAGTGAAAACACGCGCCAAGGGCGCTGGCTCCCTGGTCG
CACAGGTCAGCGACAGCCTTCGCAAGGCGATCCTTGGCGGGGACTATGCGCCGGGCGATCGGCTTCCCAGCGAAATGGAA
CTGACCGAGGCCCATGGTGTCAGCCGAACCGTTATCCGCGAGGCAGTCACCGGCCTGCGTTACGATGGGCTGGTCGAGGT
GCGCCAAGGGGCTGGCATTTTCGTCCTCAATCATCATCAATCACGCTCAAACCCGTCGAAGCTGGATCGCGCCCGGCTGT
CCTCAGATCTAGAGGTTTTGGAGATCCGCACGCCGCTGGAGATAGAGGCTGCCGGGCTTGCCGCGCTGCGCCGTTCGCCT
GCGCAGGAGGAAGCGATTTTCGACTGCCATGCAAAATTGCTGGCGTGTATCGAGGCCGACCGCTCCATTCGCGAGGCCGA
CCTGGCCCTGCATATGGCGATTGCTGCGGCCACCAATAATCCGCTGTTTACGCAATTTCTCGAGATGCACGGCGCATCCG
CTATCCCTCAGTCCAAAGTGGTTGCGGAAAACCGAGCCGCTGAGCAGACGGCCTATCGCCGCCTCATCCACAGGGAACAC
CAGGCCGTGGTCGTGGCGATTTCCGACGGCGACGAAAAAGCGGCCCGCGCCGCTATGCAGGATCATCTGCGCGGCAGCCA
GTTGCGCTACCGTGATCTGTTGCGCGATCTGCGCGGTATCGGCAGCGAGACCTGA

Upstream 100 bases:

>100_bases
GGAGGATGCCCAGCGGGTGCTTTCACGCCTGGAGCGGACGAAAAGAAAACGAGGTTACCATGATGCGGGTCGTCTAACTT
GATAGACATCAGACATATTT

Downstream 100 bases:

>100_bases
ATCTCAGGCTTCCGTCCCCCAAACCTCAACTTGGGTCAGCGCCGGAAACGGCGATGGATCATCGGCTTTCACCAGACTGT
GCAGCCGAACCCATTCGGTA

Product: transcriptional regulator GntR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MAFYRAVEFAYDSSYIFHLERRKRLCLLRQGMKVVDGVTGQVKTRAKGAGSLVAQVSDSLRKAILGGDYAPGDRLPSEME
LTEAHGVSRTVIREAVTGLRYDGLVEVRQGAGIFVLNHHQSRSNPSKLDRARLSSDLEVLEIRTPLEIEAAGLAALRRSP
AQEEAIFDCHAKLLACIEADRSIREADLALHMAIAAATNNPLFTQFLEMHGASAIPQSKVVAENRAAEQTAYRRLIHREH
QAVVVAISDGDEKAARAAMQDHLRGSQLRYRDLLRDLRGIGSET

Sequences:

>Translated_284_residues
MAFYRAVEFAYDSSYIFHLERRKRLCLLRQGMKVVDGVTGQVKTRAKGAGSLVAQVSDSLRKAILGGDYAPGDRLPSEME
LTEAHGVSRTVIREAVTGLRYDGLVEVRQGAGIFVLNHHQSRSNPSKLDRARLSSDLEVLEIRTPLEIEAAGLAALRRSP
AQEEAIFDCHAKLLACIEADRSIREADLALHMAIAAATNNPLFTQFLEMHGASAIPQSKVVAENRAAEQTAYRRLIHREH
QAVVVAISDGDEKAARAAMQDHLRGSQLRYRDLLRDLRGIGSET
>Mature_283_residues
AFYRAVEFAYDSSYIFHLERRKRLCLLRQGMKVVDGVTGQVKTRAKGAGSLVAQVSDSLRKAILGGDYAPGDRLPSEMEL
TEAHGVSRTVIREAVTGLRYDGLVEVRQGAGIFVLNHHQSRSNPSKLDRARLSSDLEVLEIRTPLEIEAAGLAALRRSPA
QEEAIFDCHAKLLACIEADRSIREADLALHMAIAAATNNPLFTQFLEMHGASAIPQSKVVAENRAAEQTAYRRLIHREHQ
AVVVAISDGDEKAARAAMQDHLRGSQLRYRDLLRDLRGIGSET

Specific function: Repressor for the uxuRBA operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790780, Length=221, Percent_Identity=31.6742081447964, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1790032, Length=220, Percent_Identity=31.8181818181818, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1789353, Length=225, Percent_Identity=28.8888888888889, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI48994961, Length=222, Percent_Identity=31.981981981982, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI87082208, Length=231, Percent_Identity=29.8701298701299, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI48994955, Length=154, Percent_Identity=28.5714285714286, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 31336; Mature: 31205

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFYRAVEFAYDSSYIFHLERRKRLCLLRQGMKVVDGVTGQVKTRAKGAGSLVAQVSDSL
CCHHHHHHHHCCCCCEEEEHHHHHHHHHHHCHHHHCCCCCCHHHHCCCHHHHHHHHHHHH
RKAILGGDYAPGDRLPSEMELTEAHGVSRTVIREAVTGLRYDGLVEVRQGAGIFVLNHHQ
HHHHHCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHCCCCCCHHEEECCCCEEEEECCC
SRSNPSKLDRARLSSDLEVLEIRTPLEIEAAGLAALRRSPAQEEAIFDCHAKLLACIEAD
CCCCHHHHHHHHHHCCCEEEEECCCCEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
RSIREADLALHMAIAAATNNPLFTQFLEMHGASAIPQSKVVAENRAAEQTAYRRLIHREH
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
QAVVVAISDGDEKAARAAMQDHLRGSQLRYRDLLRDLRGIGSET
CEEEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
AFYRAVEFAYDSSYIFHLERRKRLCLLRQGMKVVDGVTGQVKTRAKGAGSLVAQVSDSL
CHHHHHHHHCCCCCEEEEHHHHHHHHHHHCHHHHCCCCCCHHHHCCCHHHHHHHHHHHH
RKAILGGDYAPGDRLPSEMELTEAHGVSRTVIREAVTGLRYDGLVEVRQGAGIFVLNHHQ
HHHHHCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHCCCCCCHHEEECCCCEEEEECCC
SRSNPSKLDRARLSSDLEVLEIRTPLEIEAAGLAALRRSPAQEEAIFDCHAKLLACIEAD
CCCCHHHHHHHHHHCCCEEEEECCCCEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
RSIREADLALHMAIAAATNNPLFTQFLEMHGASAIPQSKVVAENRAAEQTAYRRLIHREH
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
QAVVVAISDGDEKAARAAMQDHLRGSQLRYRDLLRDLRGIGSET
CEEEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]