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The map label for this gene is pcbC [H]

Identifier: 222102539

GI number: 222102539

Start: 135594

End: 136652

Strand: Reverse

Name: pcbC [H]

Synonym: Avi_7168

Alternate gene names: 222102539

Gene position: 136652-135594 (Counterclockwise)

Preceding gene: 222102540

Following gene: 222102538

Centisome position: 21.63

GC content: 56.85

Gene sequence:

>1059_bases
ATGACACTTCAACAAAAAATCGCAACCCTGCCCTTTGTGGATATTGGCCGCTTCCATGCGGGACCAGAGGAGCGCGCAGC
CTTCATCGCAGACCTGCGTCGCATTCTGTTTGATCACGGCTTTTTCTATCTCACCGGCCATGGCGTTGATCCAAAGCTGA
TTGCGGATGTGCTCGAGACCGCCAAACGCTTTTTTGCGCTGCCGCTTGAGGAAAAGCTGAAGATTGAAATGGTGAAATCC
CGGCACTTTCGCGGCTACAATCGTGCGGGCTATGAGCACACCCGTGGTCAGCAGGATTGGCGCGAACAACTGGATATAAA
TACGGAAGGCACGCCTGTCGAGATTGGCCCGGAAACACCTGCGTGGAAACGTTTGCTCGGGCCAAATCAATGGCCAGAGG
CTATTCCAGAACTAAAGCCCCTGCTGCTGACCTATCAGGCAGAAGTCACCTGCGTTGGCATTGATGTTTTGAAGGCCATT
GCCGTGGCGCTTGACCAGCCGGAAGATGTGTTTGCGCAGATCTACGAGCCGCAACCATCGCAACTGTTGAAAATCATTCG
CTATCCCGGGCGGGATGTGGCTGAGACAGATCAGGGCGTTGGTGCCCACAAGAACGGCGGCTTCGTCACGGTTCTTTTGC
AAGACAAGGTCGAAGGTCTACGGGTGCAGACTGAAGACGGCGTGTGGCTGGATGCTCCGCCCGTACCGGGCACCTTCGTG
GTTAACACCGGGGAATTGCTGGAACTGGCCACCAATGGCTTCGTGCGGGCCGACGTGCATGATGTGGTTGCACCGCCTGC
CGGTATCGAGCGCTTCTCCGTCGCCTTCTTCTTAGGCTCGCGCTACGACGCAACGATTCCGGTGATTACGCTTCCAGACG
AGCTGCATCGAAAAGAGCGCGGCATCACGGTTGATCTGCTGAACCCGATCTTTCGGGAAGTTGGCCAGAACCATCTCAAA
AGCCGCCTGCGGTCGCACCCCGATGTTGCCCGCGCCCACCACGCTGATTTGCTCACGCCTGAGCAATTGGCCGGACAGGC
GGTAGCGCAGGCCTATTAA

Upstream 100 bases:

>100_bases
TCTATGATGTCGTGCATGGCGCGGCCTTCTTCAACTGGGCAAACCGCTTGATGCTCTCGCTGGGCGAGCCAACGCCAGCG
GCTTGAATGGAGATAATCCC

Downstream 100 bases:

>100_bases
CAGCGGCTTTGCAAAACAATGATCGACACGCCGAAAATCCGGCAATTGGCATGCTCACCACGGGTGAGGCATGTTGGAGA
ACATCATGAGCAGTGATTTA

Product: hypothetical protein

Products: NA

Alternate protein names: IPNS [H]

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MTLQQKIATLPFVDIGRFHAGPEERAAFIADLRRILFDHGFFYLTGHGVDPKLIADVLETAKRFFALPLEEKLKIEMVKS
RHFRGYNRAGYEHTRGQQDWREQLDINTEGTPVEIGPETPAWKRLLGPNQWPEAIPELKPLLLTYQAEVTCVGIDVLKAI
AVALDQPEDVFAQIYEPQPSQLLKIIRYPGRDVAETDQGVGAHKNGGFVTVLLQDKVEGLRVQTEDGVWLDAPPVPGTFV
VNTGELLELATNGFVRADVHDVVAPPAGIERFSVAFFLGSRYDATIPVITLPDELHRKERGITVDLLNPIFREVGQNHLK
SRLRSHPDVARAHHADLLTPEQLAGQAVAQAY

Sequences:

>Translated_352_residues
MTLQQKIATLPFVDIGRFHAGPEERAAFIADLRRILFDHGFFYLTGHGVDPKLIADVLETAKRFFALPLEEKLKIEMVKS
RHFRGYNRAGYEHTRGQQDWREQLDINTEGTPVEIGPETPAWKRLLGPNQWPEAIPELKPLLLTYQAEVTCVGIDVLKAI
AVALDQPEDVFAQIYEPQPSQLLKIIRYPGRDVAETDQGVGAHKNGGFVTVLLQDKVEGLRVQTEDGVWLDAPPVPGTFV
VNTGELLELATNGFVRADVHDVVAPPAGIERFSVAFFLGSRYDATIPVITLPDELHRKERGITVDLLNPIFREVGQNHLK
SRLRSHPDVARAHHADLLTPEQLAGQAVAQAY
>Mature_351_residues
TLQQKIATLPFVDIGRFHAGPEERAAFIADLRRILFDHGFFYLTGHGVDPKLIADVLETAKRFFALPLEEKLKIEMVKSR
HFRGYNRAGYEHTRGQQDWREQLDINTEGTPVEIGPETPAWKRLLGPNQWPEAIPELKPLLLTYQAEVTCVGIDVLKAIA
VALDQPEDVFAQIYEPQPSQLLKIIRYPGRDVAETDQGVGAHKNGGFVTVLLQDKVEGLRVQTEDGVWLDAPPVPGTFVV
NTGELLELATNGFVRADVHDVVAPPAGIERFSVAFFLGSRYDATIPVITLPDELHRKERGITVDLLNPIFREVGQNHLKS
RLRSHPDVARAHHADLLTPEQLAGQAVAQAY

Specific function: Removes, in the presence of oxygen, 4 hydrogen atoms from delta-L-(alpha-aminoadipyl)-L-cysteinyl-D-valine (ACV) to form the azetidinone and thiazolidine rings of isopenicillin [H]

COG id: COG3491

COG function: function code R; Isopenicillin N synthase and related dioxygenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Fe2OG dioxygenase domain [H]

Homologues:

Organism=Drosophila melanogaster, GI28572124, Length=288, Percent_Identity=25.3472222222222, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002057
- InterPro:   IPR002283
- InterPro:   IPR005123 [H]

Pfam domain/function: PF03171 2OG-FeII_Oxy [H]

EC number: =1.21.3.1 [H]

Molecular weight: Translated: 39288; Mature: 39157

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLQQKIATLPFVDIGRFHAGPEERAAFIADLRRILFDHGFFYLTGHGVDPKLIADVLET
CCHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHH
AKRFFALPLEEKLKIEMVKSRHFRGYNRAGYEHTRGQQDWREQLDINTEGTPVEIGPETP
HHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCEEECCCCH
AWKRLLGPNQWPEAIPELKPLLLTYQAEVTCVGIDVLKAIAVALDQPEDVFAQIYEPQPS
HHHHHCCCCCCHHHHHHHHHEEEEEECEEEEEHHHHHHHHHHHCCCCHHHHHHHCCCCHH
QLLKIIRYPGRDVAETDQGVGAHKNGGFVTVLLQDKVEGLRVQTEDGVWLDAPPVPGTFV
HHHHHHHCCCCCHHHHCCCCCCCCCCCEEEEEEECCCCCCEEEECCCEEEECCCCCCEEE
VNTGELLELATNGFVRADVHDVVAPPAGIERFSVAFFLGSRYDATIPVITLPDELHRKER
ECCHHHHHHHHCCEEEECHHHHHCCCCCCHHEEEEEEECCCCCCEEEEEECCHHHHHHHC
GITVDLLNPIFREVGQNHLKSRLRSHPDVARAHHADLLTPEQLAGQAVAQAY
CCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TLQQKIATLPFVDIGRFHAGPEERAAFIADLRRILFDHGFFYLTGHGVDPKLIADVLET
CHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHH
AKRFFALPLEEKLKIEMVKSRHFRGYNRAGYEHTRGQQDWREQLDINTEGTPVEIGPETP
HHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCEEECCCCH
AWKRLLGPNQWPEAIPELKPLLLTYQAEVTCVGIDVLKAIAVALDQPEDVFAQIYEPQPS
HHHHHCCCCCCHHHHHHHHHEEEEEECEEEEEHHHHHHHHHHHCCCCHHHHHHHCCCCHH
QLLKIIRYPGRDVAETDQGVGAHKNGGFVTVLLQDKVEGLRVQTEDGVWLDAPPVPGTFV
HHHHHHHCCCCCHHHHCCCCCCCCCCCEEEEEEECCCCCCEEEECCCEEEECCCCCCEEE
VNTGELLELATNGFVRADVHDVVAPPAGIERFSVAFFLGSRYDATIPVITLPDELHRKER
ECCHHHHHHHHCCEEEECHHHHHCCCCCCHHEEEEEEECCCCCCEEEEEECCHHHHHHHC
GITVDLLNPIFREVGQNHLKSRLRSHPDVARAHHADLLTPEQLAGQAVAQAY
CCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1901702 [H]