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The map label for this gene is rhtB [H]

Identifier: 222102497

GI number: 222102497

Start: 92703

End: 93350

Strand: Direct

Name: rhtB [H]

Synonym: Avi_7111

Alternate gene names: 222102497

Gene position: 92703-93350 (Clockwise)

Preceding gene: 222102496

Following gene: 222102498

Centisome position: 14.67

GC content: 52.93

Gene sequence:

>648_bases
CTGATGGATCCCGCACTCTGGCTACTTTTCGCGCTTGCCTATCTCGGAATCACCTTTTCGCCCGGTCCTAACGTCCTGAT
GGTTCTGAACCATACGGCAAAATATGGCTATCGCCACGTTTTCGTGACAATGGCCGGCAACCTTTCATGCCAGCTTTTGA
TTATCGTCGCGATTGGTGTCGGCATCGGCTCGTTGCTAACTGTAGAGAGCGCAGCCTACCACTGGATGAAGATTGCGGGC
GCACTTTATCTGATCTATCTCGGCGCGCGTATCGTTTATGATGTTTTTATCCGGGGTCGGCTGAAAGCGGTAAAAGCACC
GACGCAGCTGAATCAGGTGCATGCGCTGCCCTCGGCGCGCAAACGCTTTCTTGAGGCTTTCGCGGTTTCGGCCAGTAATC
CCAAGACGGTGATTTTTCTATCGGCGTTCCTGCCCCAATTTATCTCGCCGGAATGGCCAATCGTGCCGCAATTCGCAATC
ATGTATCTGACAATCGCGATTATCGTCATCTCCGTGCATTATATGTACGCGTTCTTGCTCATCAGAGCTCAGCGTCGCTT
CTCAGGCATGTTTTCCAGCCGTTTGTTCCCCGGGCTCAGCGCCGCGATTTATCTCTTTTTGGGAGTCACGTTGGGGGTTT
CTGCGTGA

Upstream 100 bases:

>100_bases
TACCCAACCTCGATCCGTGGGGCGAACTCGACTCTCCCGAAGATATTCACTTCTTTGAAGCCTCCACCCCCCTCAACACT
CCTGCTTTAGAAAGATCTTA

Downstream 100 bases:

>100_bases
ATTTGGGGGACGATAAACGAGGGGAAAGCCTCCGGGTTTCGGATGAGCCGGGCCATATCACCGCTCTGATGCGAGACCCG
GCCAATGCCGTAACGTTGGC

Product: RhtB family transporter

Products: homoserine lactone [Periplasm]; Proton [Cytoplasm]; homoserine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MMDPALWLLFALAYLGITFSPGPNVLMVLNHTAKYGYRHVFVTMAGNLSCQLLIIVAIGVGIGSLLTVESAAYHWMKIAG
ALYLIYLGARIVYDVFIRGRLKAVKAPTQLNQVHALPSARKRFLEAFAVSASNPKTVIFLSAFLPQFISPEWPIVPQFAI
MYLTIAIIVISVHYMYAFLLIRAQRRFSGMFSSRLFPGLSAAIYLFLGVTLGVSA

Sequences:

>Translated_215_residues
MMDPALWLLFALAYLGITFSPGPNVLMVLNHTAKYGYRHVFVTMAGNLSCQLLIIVAIGVGIGSLLTVESAAYHWMKIAG
ALYLIYLGARIVYDVFIRGRLKAVKAPTQLNQVHALPSARKRFLEAFAVSASNPKTVIFLSAFLPQFISPEWPIVPQFAI
MYLTIAIIVISVHYMYAFLLIRAQRRFSGMFSSRLFPGLSAAIYLFLGVTLGVSA
>Mature_215_residues
MMDPALWLLFALAYLGITFSPGPNVLMVLNHTAKYGYRHVFVTMAGNLSCQLLIIVAIGVGIGSLLTVESAAYHWMKIAG
ALYLIYLGARIVYDVFIRGRLKAVKAPTQLNQVHALPSARKRFLEAFAVSASNPKTVIFLSAFLPQFISPEWPIVPQFAI
MYLTIAIIVISVHYMYAFLLIRAQRRFSGMFSSRLFPGLSAAIYLFLGVTLGVSA

Specific function: Conducts the efflux of homoserine and homoserine lactone [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994979, Length=184, Percent_Identity=31.5217391304348, Blast_Score=85, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 23752; Mature: 23752

Theoretical pI: Translated: 10.39; Mature: 10.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMDPALWLLFALAYLGITFSPGPNVLMVLNHTAKYGYRHVFVTMAGNLSCQLLIIVAIGV
CCCHHHHHHHHHHHHCEEECCCCCEEEEEECCCCCCCEEEEEEEECCCCHHHHHHHHHHH
GIGSLLTVESAAYHWMKIAGALYLIYLGARIVYDVFIRGRLKAVKAPTQLNQVHALPSAR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHH
KRFLEAFAVSASNPKTVIFLSAFLPQFISPEWPIVPQFAIMYLTIAIIVISVHYMYAFLL
HHHHHHHHHCCCCCCEEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IRAQRRFSGMFSSRLFPGLSAAIYLFLGVTLGVSA
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MMDPALWLLFALAYLGITFSPGPNVLMVLNHTAKYGYRHVFVTMAGNLSCQLLIIVAIGV
CCCHHHHHHHHHHHHCEEECCCCCEEEEEECCCCCCCEEEEEEEECCCCHHHHHHHHHHH
GIGSLLTVESAAYHWMKIAGALYLIYLGARIVYDVFIRGRLKAVKAPTQLNQVHALPSAR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHH
KRFLEAFAVSASNPKTVIFLSAFLPQFISPEWPIVPQFAIMYLTIAIIVISVHYMYAFLL
HHHHHHHHHCCCCCCEEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IRAQRRFSGMFSSRLFPGLSAAIYLFLGVTLGVSA
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; homoserine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + homoserine lactone [Cytoplasm] = Proton [Cytoplasm] + homoserine lactone [Periplasm] Proton [Periplasm] + homoserine [Cytoplasm] = Proton [Cytoplasm] + homoserine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]