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The map label for this gene is gatA2 [H]

Identifier: 222102485

GI number: 222102485

Start: 82343

End: 83800

Strand: Direct

Name: gatA2 [H]

Synonym: Avi_7092

Alternate gene names: 222102485

Gene position: 82343-83800 (Clockwise)

Preceding gene: 222102484

Following gene: 222102486

Centisome position: 13.03

GC content: 56.72

Gene sequence:

>1458_bases
ATGAATGCGTCGAACGATCCCACAAAATGGACGGCATCGGAGGCCAGTCTTGCCCTTGCCGCTAAACAGATCGGCGCTGT
GGAGCTTCTGGATGCCTATCTTGCCCGACAGGCCGCTCTGGATGGTGAGATAAACGCCGTTTGTGCGCTCAATCCAGACC
TCGCCCGCACGGTTGCGCAGCAGGTCGATGCGGATCGCATTGCAGGAAAAAGCCTGCCAATTTTGGCAGGCCTGCCGATG
ACCATCAAGGATTGCTTCGACGTGGTGGGTTTGCCGACCACGGCGGGCATTCCGGACATGGCATCCTACCGACCGCAGAC
CGATGCGGATGCTGTTGCAAATCTTAGGCGTGCTGGTGCCGTGTTTTATGGCAAGACCAATACGCCGCTCGCGGCTGCCG
ACCATCAAACCTATAATCCGCTGTTTGGATTGACCCGCAATCCCCATGATCTCTCCAAAACCGTTGGAGGCTCCTCAGGC
GGCGCGGCAGCCGCATTGGCGGCAGGCTTTACCGCGCTTGAACTTGGGTCCGACATTGGCGGCTCCATTCGCATTCCAAG
CCATTATTGCGGCGTATATGGCCACAAATCCTCATGGGATACTGTATCCATGCGCGGGCATATGCCACCACCGCCCGGTC
ATCTGGCGAAAAACCCCTTGCTGGTCGCAGGCCCGATGGCGCGCTCGGCACAGGATCTTTCTGTGGCGTTCGAGATTTTG
TCATCCGATTGCAATCGCATTTTAAAACCTGCGCGACACAGCGCATTGGCGGATTTTCGCTTTGGCGTCTGGGTCGATGA
CAATCCTGTCGATCCCGTCTATGCATCGGCAATTCTGGATTTTGCCGAAAGTTTGCGCAAACAGGGCGCGAAAGTCGTCG
AAATACCCGGCGGTCCCAGTGGCGCTGATAGGCTGTTCGATACCTATATCAAGATGCTGTTTGCCACGATTGGCAGTGAA
CTGGATGACGATGAAATCGCGCGCTACACACAGGCTGGCAACGACCCGGCAACAGGCGAATTTGGCCCACTTCTCGCAGG
CGCTGTTGTTGAAAGCCATCGCAAATTTGTGGAACAGGCGCAAATGCAGGCCCGCTTTCAATCGGTCTGGGCCAAGCAGT
TTGAGACGCTCGACGTTCTTCTTTGCCCGGTTTCAATGGGCACGGCCTTCCCCCACGATTGCGACGATGGCCATGGCCCT
GTGCCGCAGATGAAAAGAACAATTCAGATTGGCAACATAAGCCAGCCTTATCTCGACAATTTGCGTTGGCCCGGCATTGC
CACACTTTTGCATCTGCCAGCCACGGTCCGCCCGTTGCCCCATCCGGTCAACGGCATGCCTGCTGGCGTGCAGATCATTG
GCCCTTATCTGGAGGACCGCACCACGCTGACATTCGCAAAGCTGTGCGATGAGGCCTTTGGCAGATCAGAAATGCCGCTC
CTGCCGCGCAAATCATAA

Upstream 100 bases:

>100_bases
TGGGGCTGATTGTGATTGTCACCCTTGTTTATGCACCGCGTGGCCTTTGGCCTGCGCTGCACTCTCTCTTCAGACGAATG
AGCATTGAAAGGAAATCCGC

Downstream 100 bases:

>100_bases
CAGTTCATTCTTCTAGGCCGCACACTCATAAACCGGGTTTGCAAATCGGCCTGATTTTGATTCACTGAGGCCTTGATTTG
GAGGCCTCTCATGACCCGTC

Product: amidase

Products: NA

Alternate protein names: Glu-ADT subunit A 2 [H]

Number of amino acids: Translated: 485; Mature: 485

Protein sequence:

>485_residues
MNASNDPTKWTASEASLALAAKQIGAVELLDAYLARQAALDGEINAVCALNPDLARTVAQQVDADRIAGKSLPILAGLPM
TIKDCFDVVGLPTTAGIPDMASYRPQTDADAVANLRRAGAVFYGKTNTPLAAADHQTYNPLFGLTRNPHDLSKTVGGSSG
GAAAALAAGFTALELGSDIGGSIRIPSHYCGVYGHKSSWDTVSMRGHMPPPPGHLAKNPLLVAGPMARSAQDLSVAFEIL
SSDCNRILKPARHSALADFRFGVWVDDNPVDPVYASAILDFAESLRKQGAKVVEIPGGPSGADRLFDTYIKMLFATIGSE
LDDDEIARYTQAGNDPATGEFGPLLAGAVVESHRKFVEQAQMQARFQSVWAKQFETLDVLLCPVSMGTAFPHDCDDGHGP
VPQMKRTIQIGNISQPYLDNLRWPGIATLLHLPATVRPLPHPVNGMPAGVQIIGPYLEDRTTLTFAKLCDEAFGRSEMPL
LPRKS

Sequences:

>Translated_485_residues
MNASNDPTKWTASEASLALAAKQIGAVELLDAYLARQAALDGEINAVCALNPDLARTVAQQVDADRIAGKSLPILAGLPM
TIKDCFDVVGLPTTAGIPDMASYRPQTDADAVANLRRAGAVFYGKTNTPLAAADHQTYNPLFGLTRNPHDLSKTVGGSSG
GAAAALAAGFTALELGSDIGGSIRIPSHYCGVYGHKSSWDTVSMRGHMPPPPGHLAKNPLLVAGPMARSAQDLSVAFEIL
SSDCNRILKPARHSALADFRFGVWVDDNPVDPVYASAILDFAESLRKQGAKVVEIPGGPSGADRLFDTYIKMLFATIGSE
LDDDEIARYTQAGNDPATGEFGPLLAGAVVESHRKFVEQAQMQARFQSVWAKQFETLDVLLCPVSMGTAFPHDCDDGHGP
VPQMKRTIQIGNISQPYLDNLRWPGIATLLHLPATVRPLPHPVNGMPAGVQIIGPYLEDRTTLTFAKLCDEAFGRSEMPL
LPRKS
>Mature_485_residues
MNASNDPTKWTASEASLALAAKQIGAVELLDAYLARQAALDGEINAVCALNPDLARTVAQQVDADRIAGKSLPILAGLPM
TIKDCFDVVGLPTTAGIPDMASYRPQTDADAVANLRRAGAVFYGKTNTPLAAADHQTYNPLFGLTRNPHDLSKTVGGSSG
GAAAALAAGFTALELGSDIGGSIRIPSHYCGVYGHKSSWDTVSMRGHMPPPPGHLAKNPLLVAGPMARSAQDLSVAFEIL
SSDCNRILKPARHSALADFRFGVWVDDNPVDPVYASAILDFAESLRKQGAKVVEIPGGPSGADRLFDTYIKMLFATIGSE
LDDDEIARYTQAGNDPATGEFGPLLAGAVVESHRKFVEQAQMQARFQSVWAKQFETLDVLLCPVSMGTAFPHDCDDGHGP
VPQMKRTIQIGNISQPYLDNLRWPGIATLLHLPATVRPLPHPVNGMPAGVQIIGPYLEDRTTLTFAKLCDEAFGRSEMPL
LPRKS

Specific function: Furnishes a means for formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu- tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activa

COG id: COG0154

COG function: function code J; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amidase family [H]

Homologues:

Organism=Homo sapiens, GI195972892, Length=491, Percent_Identity=25.8655804480652, Blast_Score=145, Evalue=8e-35,
Organism=Homo sapiens, GI222831590, Length=507, Percent_Identity=24.8520710059172, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI166795287, Length=286, Percent_Identity=29.7202797202797, Blast_Score=80, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17537465, Length=500, Percent_Identity=27.2, Blast_Score=141, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI17538252, Length=510, Percent_Identity=26.4705882352941, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17556264, Length=197, Percent_Identity=35.5329949238579, Blast_Score=119, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI71990152, Length=299, Percent_Identity=28.7625418060201, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17538254, Length=419, Percent_Identity=25.7756563245823, Blast_Score=101, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17556276, Length=290, Percent_Identity=29.6551724137931, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17556278, Length=290, Percent_Identity=29.6551724137931, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17543272, Length=435, Percent_Identity=23.9080459770115, Blast_Score=77, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6320448, Length=524, Percent_Identity=25.1908396946565, Blast_Score=95, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6319685, Length=432, Percent_Identity=26.6203703703704, Blast_Score=84, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24644968, Length=509, Percent_Identity=26.3261296660118, Blast_Score=135, Evalue=9e-32,
Organism=Drosophila melanogaster, GI21356731, Length=239, Percent_Identity=35.5648535564854, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24648435, Length=262, Percent_Identity=32.4427480916031, Blast_Score=128, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24648437, Length=262, Percent_Identity=32.4427480916031, Blast_Score=128, Evalue=1e-29,
Organism=Drosophila melanogaster, GI45550774, Length=262, Percent_Identity=32.4427480916031, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24652985, Length=299, Percent_Identity=32.7759197324415, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI19922090, Length=299, Percent_Identity=32.7759197324415, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24652981, Length=299, Percent_Identity=32.7759197324415, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24652983, Length=299, Percent_Identity=32.7759197324415, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI161078093, Length=512, Percent_Identity=27.734375, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI24648441, Length=199, Percent_Identity=36.1809045226131, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24648439, Length=199, Percent_Identity=36.1809045226131, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24648113, Length=195, Percent_Identity=36.9230769230769, Blast_Score=75, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000120
- InterPro:   IPR020556
- InterPro:   IPR004412 [H]

Pfam domain/function: PF01425 Amidase [H]

EC number: NA

Molecular weight: Translated: 51685; Mature: 51685

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNASNDPTKWTASEASLALAAKQIGAVELLDAYLARQAALDGEINAVCALNPDLARTVAQ
CCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHH
QVDADRIAGKSLPILAGLPMTIKDCFDVVGLPTTAGIPDMASYRPQTDADAVANLRRAGA
HHCHHHHCCCCCCEEECCCHHHHHHHHHHCCCCCCCCCCHHHCCCCCCHHHHHHHHHHCE
VFYGKTNTPLAAADHQTYNPLFGLTRNPHDLSKTVGGSSGGAAAALAAGFTALELGSDIG
EEECCCCCCCEECCCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHCHHHHHHCCCCC
GSIRIPSHYCGVYGHKSSWDTVSMRGHMPPPPGHLAKNPLLVAGPMARSAQDLSVAFEIL
CEEECCHHHCCCCCCCCCCCEEEECCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHH
SSDCNRILKPARHSALADFRFGVWVDDNPVDPVYASAILDFAESLRKQGAKVVEIPGGPS
HHHHHHHHHHHHHHHHHHCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCC
GADRLFDTYIKMLFATIGSELDDDEIARYTQAGNDPATGEFGPLLAGAVVESHRKFVEQA
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
QMQARFQSVWAKQFETLDVLLCPVSMGTAFPHDCDDGHGPVPQMKRTIQIGNISQPYLDN
HHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCCHHHHHEEEECCCCCHHHHC
LRWPGIATLLHLPATVRPLPHPVNGMPAGVQIIGPYLEDRTTLTFAKLCDEAFGRSEMPL
CCCCCHHHHHHCCCCCCCCCCCCCCCCCCCEEECCHHCCCHHHHHHHHHHHHHCCCCCCC
LPRKS
CCCCC
>Mature Secondary Structure
MNASNDPTKWTASEASLALAAKQIGAVELLDAYLARQAALDGEINAVCALNPDLARTVAQ
CCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHH
QVDADRIAGKSLPILAGLPMTIKDCFDVVGLPTTAGIPDMASYRPQTDADAVANLRRAGA
HHCHHHHCCCCCCEEECCCHHHHHHHHHHCCCCCCCCCCHHHCCCCCCHHHHHHHHHHCE
VFYGKTNTPLAAADHQTYNPLFGLTRNPHDLSKTVGGSSGGAAAALAAGFTALELGSDIG
EEECCCCCCCEECCCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHCHHHHHHCCCCC
GSIRIPSHYCGVYGHKSSWDTVSMRGHMPPPPGHLAKNPLLVAGPMARSAQDLSVAFEIL
CEEECCHHHCCCCCCCCCCCEEEECCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHH
SSDCNRILKPARHSALADFRFGVWVDDNPVDPVYASAILDFAESLRKQGAKVVEIPGGPS
HHHHHHHHHHHHHHHHHHCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCC
GADRLFDTYIKMLFATIGSELDDDEIARYTQAGNDPATGEFGPLLAGAVVESHRKFVEQA
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
QMQARFQSVWAKQFETLDVLLCPVSMGTAFPHDCDDGHGPVPQMKRTIQIGNISQPYLDN
HHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCCHHHHHEEEECCCCCHHHHC
LRWPGIATLLHLPATVRPLPHPVNGMPAGVQIIGPYLEDRTTLTFAKLCDEAFGRSEMPL
CCCCCHHHHHHCCCCCCCCCCCCCCCCCCCEEECCHHCCCHHHHHHHHHHHHHCCCCCCC
LPRKS
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]