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The map label for this gene is dapG [H]

Identifier: 222097245

GI number: 222097245

Start: 3544518

End: 3545750

Strand: Reverse

Name: dapG [H]

Synonym: BCQ_3585

Alternate gene names: 222097245

Gene position: 3545750-3544518 (Counterclockwise)

Preceding gene: 222097246

Following gene: 222097244

Centisome position: 68.0

GC content: 38.69

Gene sequence:

>1233_bases
ATGAAAATTATTGTTCAAAAATTTGGTGGCACATCTGTACGTGATGAAAATGGACGTAAGCATGCGCTTCATCATATAAA
AAAATCGCTAGATGCGGGTTATAAAGTAGTGACTGTCGTATCTGCTATGGGTCGTAAAGGTGAACCATATGCAACTGATA
CGTTGTTAAGTCTTGTAAATCAAGAGGAATCTCACATTTCTAATCGTGAGCAAGATTTATTATTATCATGTGGAGAATTA
ATCTCAGCAATCGTTTTCTCTAACATGTTAAATGAGAACGGTATAAAAGCGGCGGCATTAAATGGTGCACAAGCTGGTTT
TGTAACAAATGATGATTTTACAAATGCTAAGATTATTGAAATGAATTGTGATCGTATACACGAAGAGCTAGAAAATGTAG
ATGTAATCGTTGTGACAGGATTCCAAGGACAAACGAAAAAAGGTGATACGACAACACTTGGACGCGGAGGTAGTGATACT
TCAGCTTCAGCTTTAGGTGTTGCGCTTCATGCTGAATATATCGATATCTTCACAGATGTAGAAGGTGTGATGACTGCGGA
TCCTCGCATTGTAAAAGATGCACGTCATCTTCAAACTGTAACGTATAACGAAATTTGTAACATGGCATACCAAGGTGCAA
AAGTCGTTCATCCACGTGCAGTTGAAATTGCGATGCATGCAAAAGTACCGCTTCGTGTACGTTCTACGTACTCTGATAGT
GAAGGTACGCTTATTTCAGCATCTGACGGCGCTACAAAAGGCCGTGATGTAGAAGAACGTCCTGTTACAGGTATTGCACA
TGTATCAAATGTGACGCAAATTAAAGTACTTGCAAAAGAAACAGCATATGATTTGCAGCAGCATGTGTTTAAAGAAATGG
CGAATGAAGGAATCAGTGTCGATTTAATTAACATTTCACCTACTGGGGTAGCTTATACGGTGAGTGATAATGTATCAAAT
CGTGCAGTTGAACTATTACAAAACCTTGGATATGAGCCAATTGTGACAGAGCATTGTGCGAAAGTATCTATTGTAGGAGC
TGGAATGGCAGGATACCCAGGGGTTACTGCGAAAATCGTTACAGCTTTAGCTGAAAAAGGTATTCAAATTCTGCAATCAG
CAGATAGTCATACAACTATTTGGGTTCTTGTAAAAGAAACTGATTTAGTGGAGGCTGTAAATGCATTACATAGTGCGTTT
GAGCTTTCAAAAGAAAAGCAACTGGAACAATAA

Upstream 100 bases:

>100_bases
CTGATAACTTATTAAAAGGCGCTGCATGGAATTCTGTTCAAATTGCAGAGCGCTTAGTAAAATTACAATTAGTGTAAACG
GCTAAGAGAAGGTGCAAAAT

Downstream 100 bases:

>100_bases
GGAGTGAGACCATGATAGATTTTGGGACAATTGCAACCGCGATGGTAACACCGTTTGATATAAACGGCAATATCGATTTT
GCAAAGACAACGAAATTGGT

Product: aspartate kinase i

Products: NA

Alternate protein names: Aspartate kinase 1; Aspartokinase I [H]

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MKIIVQKFGGTSVRDENGRKHALHHIKKSLDAGYKVVTVVSAMGRKGEPYATDTLLSLVNQEESHISNREQDLLLSCGEL
ISAIVFSNMLNENGIKAAALNGAQAGFVTNDDFTNAKIIEMNCDRIHEELENVDVIVVTGFQGQTKKGDTTTLGRGGSDT
SASALGVALHAEYIDIFTDVEGVMTADPRIVKDARHLQTVTYNEICNMAYQGAKVVHPRAVEIAMHAKVPLRVRSTYSDS
EGTLISASDGATKGRDVEERPVTGIAHVSNVTQIKVLAKETAYDLQQHVFKEMANEGISVDLINISPTGVAYTVSDNVSN
RAVELLQNLGYEPIVTEHCAKVSIVGAGMAGYPGVTAKIVTALAEKGIQILQSADSHTTIWVLVKETDLVEAVNALHSAF
ELSKEKQLEQ

Sequences:

>Translated_410_residues
MKIIVQKFGGTSVRDENGRKHALHHIKKSLDAGYKVVTVVSAMGRKGEPYATDTLLSLVNQEESHISNREQDLLLSCGEL
ISAIVFSNMLNENGIKAAALNGAQAGFVTNDDFTNAKIIEMNCDRIHEELENVDVIVVTGFQGQTKKGDTTTLGRGGSDT
SASALGVALHAEYIDIFTDVEGVMTADPRIVKDARHLQTVTYNEICNMAYQGAKVVHPRAVEIAMHAKVPLRVRSTYSDS
EGTLISASDGATKGRDVEERPVTGIAHVSNVTQIKVLAKETAYDLQQHVFKEMANEGISVDLINISPTGVAYTVSDNVSN
RAVELLQNLGYEPIVTEHCAKVSIVGAGMAGYPGVTAKIVTALAEKGIQILQSADSHTTIWVLVKETDLVEAVNALHSAF
ELSKEKQLEQ
>Mature_410_residues
MKIIVQKFGGTSVRDENGRKHALHHIKKSLDAGYKVVTVVSAMGRKGEPYATDTLLSLVNQEESHISNREQDLLLSCGEL
ISAIVFSNMLNENGIKAAALNGAQAGFVTNDDFTNAKIIEMNCDRIHEELENVDVIVVTGFQGQTKKGDTTTLGRGGSDT
SASALGVALHAEYIDIFTDVEGVMTADPRIVKDARHLQTVTYNEICNMAYQGAKVVHPRAVEIAMHAKVPLRVRSTYSDS
EGTLISASDGATKGRDVEERPVTGIAHVSNVTQIKVLAKETAYDLQQHVFKEMANEGISVDLINISPTGVAYTVSDNVSN
RAVELLQNLGYEPIVTEHCAKVSIVGAGMAGYPGVTAKIVTALAEKGIQILQSADSHTTIWVLVKETDLVEAVNALHSAF
ELSKEKQLEQ

Specific function: Catalyzes 2 nonconsecutive reactions in the common biosynthetic pathway leading from Asp to diaminopimelate and Lys, to Met, and to Thr and Ile. [C]

COG id: COG0527

COG function: function code E; Aspartokinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartokinase family [H]

Homologues:

Organism=Escherichia coli, GI1786183, Length=279, Percent_Identity=35.1254480286738, Blast_Score=145, Evalue=7e-36,
Organism=Escherichia coli, GI1790455, Length=347, Percent_Identity=31.1239193083574, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1790376, Length=169, Percent_Identity=31.9526627218935, Blast_Score=87, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6320893, Length=393, Percent_Identity=27.735368956743, Blast_Score=130, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR005260
- InterPro:   IPR001341
- InterPro:   IPR018042 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.2.4 [H]

Molecular weight: Translated: 44240; Mature: 44240

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS00324 ASPARTOKINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIVQKFGGTSVRDENGRKHALHHIKKSLDAGYKVVTVVSAMGRKGEPYATDTLLSLVN
CEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHC
QEESHISNREQDLLLSCGELISAIVFSNMLNENGIKAAALNGAQAGFVTNDDFTNAKIIE
CHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEECCCCCCCEEEE
MNCDRIHEELENVDVIVVTGFQGQTKKGDTTTLGRGGSDTSASALGVALHAEYIDIFTDV
ECHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
EGVMTADPRIVKDARHLQTVTYNEICNMAYQGAKVVHPRAVEIAMHAKVPLRVRSTYSDS
CCEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEEEECCCCEEEECCCCCC
EGTLISASDGATKGRDVEERPVTGIAHVSNVTQIKVLAKETAYDLQQHVFKEMANEGISV
CCCEEECCCCCCCCCCCCCCCCCHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCEE
DLINISPTGVAYTVSDNVSNRAVELLQNLGYEPIVTEHCAKVSIVGAGMAGYPGVTAKIV
EEEEECCCCEEEEECCCCHHHHHHHHHHCCCCCCHHHHCCEEEEEECCCCCCCCHHHHHH
TALAEKGIQILQSADSHTTIWVLVKETDLVEAVNALHSAFELSKEKQLEQ
HHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIIVQKFGGTSVRDENGRKHALHHIKKSLDAGYKVVTVVSAMGRKGEPYATDTLLSLVN
CEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHC
QEESHISNREQDLLLSCGELISAIVFSNMLNENGIKAAALNGAQAGFVTNDDFTNAKIIE
CHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEECCCCCCCEEEE
MNCDRIHEELENVDVIVVTGFQGQTKKGDTTTLGRGGSDTSASALGVALHAEYIDIFTDV
ECHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
EGVMTADPRIVKDARHLQTVTYNEICNMAYQGAKVVHPRAVEIAMHAKVPLRVRSTYSDS
CCEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEEEECCCCEEEECCCCCC
EGTLISASDGATKGRDVEERPVTGIAHVSNVTQIKVLAKETAYDLQQHVFKEMANEGISV
CCCEEECCCCCCCCCCCCCCCCCHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCEE
DLINISPTGVAYTVSDNVSNRAVELLQNLGYEPIVTEHCAKVSIVGAGMAGYPGVTAKIV
EEEEECCCCEEEEECCCCHHHHHHHHHHCCCCCCHHHHCCEEEEEECCCCCCCCHHHHHH
TALAEKGIQILQSADSHTTIWVLVKETDLVEAVNALHSAFELSKEKQLEQ
HHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8098035; 9384377 [H]