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The map label for this gene is hflx [H]

Identifier: 222097161

GI number: 222097161

Start: 3452444

End: 3453718

Strand: Reverse

Name: hflx [H]

Synonym: BCQ_3501

Alternate gene names: 222097161

Gene position: 3453718-3452444 (Counterclockwise)

Preceding gene: 222097164

Following gene: 222097160

Centisome position: 66.24

GC content: 36.39

Gene sequence:

>1275_bases
ATGGAAGAAAAAGAGAAAGTCATATTAGTGGGCTGTCAATTGCCGCAAGATGATGATGAAAAATTTATGCATTCCATGAA
AGAACTTGCATCATTAGCGAAAACTGCACGAGCAGAATTGTTAGTGTCTACAACGCAAAAACGACCGAAGTTTCATCCGG
CGACTTATATAGGTAAAGGTAAATTAGAAGAGCTTACAATGTTAACTGAAGAACTAGAACCGGATGTTATCGTATTTAAT
AACGAATTAACACCGAGTCAAATTCGGAATTTATCCGCAGTATTAGATGCGAGGGTAATTGATCGAACGCAACTCATATT
AGATATTTTTGCGCAACGTGCGAAGTCGAGAGAAGGGAAGCTTCAAGTAGAATTAGCTCAGTTGCAATATACAATGCCGC
GTCTTATGGGGCAAGGATTGTCTTTATCACGTCTTGGTGGTGGTATTGGAACGAGAGGGCCAGGTGAAACGAAACTTGAG
ACTGATCGTCGTCATATTCGAGCGCGCGTTGATGAAATAAAGAAGCAACTTGCAGTTGTTGTGGAGCATCGAAAAAGATA
TCGTGAAAGAAGAAAAGATAATAAAGTATTCCAAGTTTCATTAATAGGATATACGAATGCGGGAAAATCTACACTGTTTA
ATAGATTAACGGAAGCTGATACGTTTGAAGAGAATTTGTTGTTTGCGACGCTAGACCCGACGACAAGGAAGATGCCGTTA
CCTTCTGGTTATACAGTATTACTAACTGATACGGTTGGTTTTATACAAGATTTACCTACGTCATTAATTGCTGCATTCCG
TTCGACGTTAGAAGAAGCTGGTGAAGCGGATGTTATTTTACATGTTGTGGATTCTGCAGATCCTAATTATGTAGGGCATG
AGAAAACAGTAAAACAATTATTGTCAGAACTCGAAATAAATCATATTCCTATTATTACGTTATATAATAAAAAAGATGAA
TTACATCAAAACTTTATTCCGTTTCCGAAAAATGACTTCTTAATGACTAGTGCTTTTGAAGAAAAGGATCTATTACATAT
AAAAGAAGCGATAGAAACGAAAATGAAGGAAGAAATGAATCGTTATCAAGTGGAGATTCCTCCGAGTGAAGGTAAGTTAT
TAACTCTATTAAAGACGGAGACGCTATTAACAAAAATGGAGTTTTTGGAAGATAAATTTGTATATGATTGCGCGGGGTAT
ATTTTTGCTCATTCATCGCTTAATGTACAATTAAAGAGATTTTTAGTGGAAGAAGGAGAAAATAAAAATGTTTGA

Upstream 100 bases:

>100_bases
CATGCCATGAATTTTCTCCCCCGCTAACTAGATGAAATGTGCTTCCTCTGCTATTATATTAGAAGGTTTAAATTTCGAAA
AGGATGAGTGAACATATTTG

Downstream 100 bases:

>100_bases
TCGTTTGAAAAATGGAGAAAAAATTGCTCCAATCGTAAAAGAAGTAGAGAGCCAAATTACAGAAGTACATAAACGTGCGG
ATGAAGTAATTGAAAGTAAT

Product: GTP-binding protein (hflx)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MEEKEKVILVGCQLPQDDDEKFMHSMKELASLAKTARAELLVSTTQKRPKFHPATYIGKGKLEELTMLTEELEPDVIVFN
NELTPSQIRNLSAVLDARVIDRTQLILDIFAQRAKSREGKLQVELAQLQYTMPRLMGQGLSLSRLGGGIGTRGPGETKLE
TDRRHIRARVDEIKKQLAVVVEHRKRYRERRKDNKVFQVSLIGYTNAGKSTLFNRLTEADTFEENLLFATLDPTTRKMPL
PSGYTVLLTDTVGFIQDLPTSLIAAFRSTLEEAGEADVILHVVDSADPNYVGHEKTVKQLLSELEINHIPIITLYNKKDE
LHQNFIPFPKNDFLMTSAFEEKDLLHIKEAIETKMKEEMNRYQVEIPPSEGKLLTLLKTETLLTKMEFLEDKFVYDCAGY
IFAHSSLNVQLKRFLVEEGENKNV

Sequences:

>Translated_424_residues
MEEKEKVILVGCQLPQDDDEKFMHSMKELASLAKTARAELLVSTTQKRPKFHPATYIGKGKLEELTMLTEELEPDVIVFN
NELTPSQIRNLSAVLDARVIDRTQLILDIFAQRAKSREGKLQVELAQLQYTMPRLMGQGLSLSRLGGGIGTRGPGETKLE
TDRRHIRARVDEIKKQLAVVVEHRKRYRERRKDNKVFQVSLIGYTNAGKSTLFNRLTEADTFEENLLFATLDPTTRKMPL
PSGYTVLLTDTVGFIQDLPTSLIAAFRSTLEEAGEADVILHVVDSADPNYVGHEKTVKQLLSELEINHIPIITLYNKKDE
LHQNFIPFPKNDFLMTSAFEEKDLLHIKEAIETKMKEEMNRYQVEIPPSEGKLLTLLKTETLLTKMEFLEDKFVYDCAGY
IFAHSSLNVQLKRFLVEEGENKNV
>Mature_424_residues
MEEKEKVILVGCQLPQDDDEKFMHSMKELASLAKTARAELLVSTTQKRPKFHPATYIGKGKLEELTMLTEELEPDVIVFN
NELTPSQIRNLSAVLDARVIDRTQLILDIFAQRAKSREGKLQVELAQLQYTMPRLMGQGLSLSRLGGGIGTRGPGETKLE
TDRRHIRARVDEIKKQLAVVVEHRKRYRERRKDNKVFQVSLIGYTNAGKSTLFNRLTEADTFEENLLFATLDPTTRKMPL
PSGYTVLLTDTVGFIQDLPTSLIAAFRSTLEEAGEADVILHVVDSADPNYVGHEKTVKQLLSELEINHIPIITLYNKKDE
LHQNFIPFPKNDFLMTSAFEEKDLLHIKEAIETKMKEEMNRYQVEIPPSEGKLLTLLKTETLLTKMEFLEDKFVYDCAGY
IFAHSSLNVQLKRFLVEEGENKNV

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=239, Percent_Identity=31.7991631799163, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI310133116, Length=145, Percent_Identity=39.3103448275862, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI310124269, Length=137, Percent_Identity=40.1459854014599, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI310124267, Length=137, Percent_Identity=40.1459854014599, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI310124171, Length=137, Percent_Identity=40.1459854014599, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI310124169, Length=137, Percent_Identity=40.1459854014599, Blast_Score=97, Evalue=3e-20,
Organism=Escherichia coli, GI1790615, Length=375, Percent_Identity=41.8666666666667, Blast_Score=276, Evalue=2e-75,
Organism=Caenorhabditis elegans, GI17561038, Length=285, Percent_Identity=32.280701754386, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24650079, Length=285, Percent_Identity=35.7894736842105, Blast_Score=126, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 48363; Mature: 48363

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEKEKVILVGCQLPQDDDEKFMHSMKELASLAKTARAELLVSTTQKRPKFHPATYIGKG
CCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCC
KLEELTMLTEELEPDVIVFNNELTPSQIRNLSAVLDARVIDRTQLILDIFAQRAKSREGK
CHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LQVELAQLQYTMPRLMGQGLSLSRLGGGIGTRGPGETKLETDRRHIRARVDEIKKQLAVV
EEEEHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VEHRKRYRERRKDNKVFQVSLIGYTNAGKSTLFNRLTEADTFEENLLFATLDPTTRKMPL
HHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHCCHHCCEEEEEECCCCCCCCC
PSGYTVLLTDTVGFIQDLPTSLIAAFRSTLEEAGEADVILHVVDSADPNYVGHEKTVKQL
CCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHH
LSELEINHIPIITLYNKKDELHQNFIPFPKNDFLMTSAFEEKDLLHIKEAIETKMKEEMN
HHHCCCCCCEEEEEECCHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHH
RYQVEIPPSEGKLLTLLKTETLLTKMEFLEDKFVYDCAGYIFAHSSLNVQLKRFLVEEGE
HEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCC
NKNV
CCCC
>Mature Secondary Structure
MEEKEKVILVGCQLPQDDDEKFMHSMKELASLAKTARAELLVSTTQKRPKFHPATYIGKG
CCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCC
KLEELTMLTEELEPDVIVFNNELTPSQIRNLSAVLDARVIDRTQLILDIFAQRAKSREGK
CHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LQVELAQLQYTMPRLMGQGLSLSRLGGGIGTRGPGETKLETDRRHIRARVDEIKKQLAVV
EEEEHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VEHRKRYRERRKDNKVFQVSLIGYTNAGKSTLFNRLTEADTFEENLLFATLDPTTRKMPL
HHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHCCHHCCEEEEEECCCCCCCCC
PSGYTVLLTDTVGFIQDLPTSLIAAFRSTLEEAGEADVILHVVDSADPNYVGHEKTVKQL
CCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHH
LSELEINHIPIITLYNKKDELHQNFIPFPKNDFLMTSAFEEKDLLHIKEAIETKMKEEMN
HHHCCCCCCEEEEEECCHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHH
RYQVEIPPSEGKLLTLLKTETLLTKMEFLEDKFVYDCAGYIFAHSSLNVQLKRFLVEEGE
HEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCC
NKNV
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]