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The map label for this gene is alsR [H]

Identifier: 222097131

GI number: 222097131

Start: 3424832

End: 3425659

Strand: Reverse

Name: alsR [H]

Synonym: BCQ_3471

Alternate gene names: 222097131

Gene position: 3425659-3424832 (Counterclockwise)

Preceding gene: 222097134

Following gene: 222097130

Centisome position: 65.7

GC content: 36.35

Gene sequence:

>828_bases
ATGACACAACCACCGCTTAGTCAACAAATTCAGCAATTAGAAAAAGAAATGGGAGTTATGTTATTTTCAAGAACGAAGAG
AAAGGTTGAATTAACAGAAGCTGGAGAAATGTTTTTGAAAGAAGTAAAAAAAGCGTTCGAACAAATTGAAAAAGCGGTAG
AAATTGCACAAAGTGCCCAAAGGGGAGAAGTGGGCTCACTTTCAATTGGTTTTGTAGGTGCGGCGATATATGATATTTTA
CCATCTATCGTAAGGGAGTATAGAAAGAAATTTCCGAGGGTGTCTGTTGCATTACATGAATTATCTACTCCAGATCAAGT
GCATGCACTTCATGATAATCGAATTGATATTGGATTTTTGCGTCCACCAATCCCAACACAATTATTAGAGTTAGAGCCAA
TACAAAAACTATCTTGTACTTTATGTTTACCGAAGGCTCATCCACTTGCAGAGAAAGATGAAATACATATAGAAGATTTA
CGGGATGAACCGTTTGTATTTATTACGAGACCAGTATGGCCAGCGTTATACGATACAATTTTATCACTTTGCCGCGACGT
CGGGTTTAGTCCGCGTATCGTACAAGAAGCGACGGAATATCAAACAGTTATGGGACTTGTAGCAGCAGGGATTGGAATTA
CAGTAATACCGGTATCGGCAAATAAATTATATAAAACGGAAGTTGTATATAAAGAGCTATATGATTCTAATTTTGTTGCG
GAAATGTCAGTCGCTTACAAAAAAATGAATAGCAATCCAGAGCTTTTAGAGTTTTTAAAAATTGCAAGAGAGAAGAAAAG
AATAGAAGTTGAGGATGAGATTAATTAA

Upstream 100 bases:

>100_bases
GAAATGGAAAAGGGTGTCCAAAATGGAATTACGGCATTTGCAATATTTTGTTGTAGTGGCAGAGGAGTTACACTTTGGAC
GAGCGGCTGCTCGTTTACAA

Downstream 100 bases:

>100_bases
GTTATTGAAAAATACACCTCGTTAAACACTAAAGCGGAAATGTAATTGCATTTCCGCTTTAGTGTTCTTTTTTAGTTCTA
TACGAAAGAGATAAACATGT

Product: transcriptional regulator, lysr family

Products: NA

Alternate protein names: Als operon regulatory protein [H]

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MTQPPLSQQIQQLEKEMGVMLFSRTKRKVELTEAGEMFLKEVKKAFEQIEKAVEIAQSAQRGEVGSLSIGFVGAAIYDIL
PSIVREYRKKFPRVSVALHELSTPDQVHALHDNRIDIGFLRPPIPTQLLELEPIQKLSCTLCLPKAHPLAEKDEIHIEDL
RDEPFVFITRPVWPALYDTILSLCRDVGFSPRIVQEATEYQTVMGLVAAGIGITVIPVSANKLYKTEVVYKELYDSNFVA
EMSVAYKKMNSNPELLEFLKIAREKKRIEVEDEIN

Sequences:

>Translated_275_residues
MTQPPLSQQIQQLEKEMGVMLFSRTKRKVELTEAGEMFLKEVKKAFEQIEKAVEIAQSAQRGEVGSLSIGFVGAAIYDIL
PSIVREYRKKFPRVSVALHELSTPDQVHALHDNRIDIGFLRPPIPTQLLELEPIQKLSCTLCLPKAHPLAEKDEIHIEDL
RDEPFVFITRPVWPALYDTILSLCRDVGFSPRIVQEATEYQTVMGLVAAGIGITVIPVSANKLYKTEVVYKELYDSNFVA
EMSVAYKKMNSNPELLEFLKIAREKKRIEVEDEIN
>Mature_274_residues
TQPPLSQQIQQLEKEMGVMLFSRTKRKVELTEAGEMFLKEVKKAFEQIEKAVEIAQSAQRGEVGSLSIGFVGAAIYDILP
SIVREYRKKFPRVSVALHELSTPDQVHALHDNRIDIGFLRPPIPTQLLELEPIQKLSCTLCLPKAHPLAEKDEIHIEDLR
DEPFVFITRPVWPALYDTILSLCRDVGFSPRIVQEATEYQTVMGLVAAGIGITVIPVSANKLYKTEVVYKELYDSNFVAE
MSVAYKKMNSNPELLEFLKIAREKKRIEVEDEIN

Specific function: Regulates the expression of the alsSD operon for acetoin biosynthesis [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787879, Length=249, Percent_Identity=34.136546184739, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI2367136, Length=261, Percent_Identity=29.8850574712644, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1788887, Length=265, Percent_Identity=32.8301886792453, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1790399, Length=222, Percent_Identity=29.7297297297297, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI157672245, Length=219, Percent_Identity=26.9406392694064, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787530, Length=223, Percent_Identity=28.2511210762332, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI145693105, Length=217, Percent_Identity=23.963133640553, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1789204, Length=224, Percent_Identity=26.3392857142857, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788297, Length=228, Percent_Identity=27.1929824561404, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790262, Length=216, Percent_Identity=26.3888888888889, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1788748, Length=239, Percent_Identity=24.6861924686192, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1789506, Length=219, Percent_Identity=24.2009132420091, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788481, Length=171, Percent_Identity=27.4853801169591, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787806, Length=217, Percent_Identity=22.1198156682028, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787601, Length=151, Percent_Identity=25.8278145695364, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31240; Mature: 31109

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQPPLSQQIQQLEKEMGVMLFSRTKRKVELTEAGEMFLKEVKKAFEQIEKAVEIAQSAQ
CCCCCHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RGEVGSLSIGFVGAAIYDILPSIVREYRKKFPRVSVALHELSTPDQVHALHDNRIDIGFL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHCCCCEEEEEC
RPPIPTQLLELEPIQKLSCTLCLPKAHPLAEKDEIHIEDLRDEPFVFITRPVWPALYDTI
CCCCCHHHHCCCCHHHHHHEEECCCCCCCCCCCCEEHCCCCCCCEEEEECCHHHHHHHHH
LSLCRDVGFSPRIVQEATEYQTVMGLVAAGIGITVIPVSANKLYKTEVVYKELYDSNFVA
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHCCCHHH
EMSVAYKKMNSNPELLEFLKIAREKKRIEVEDEIN
HHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TQPPLSQQIQQLEKEMGVMLFSRTKRKVELTEAGEMFLKEVKKAFEQIEKAVEIAQSAQ
CCCCHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RGEVGSLSIGFVGAAIYDILPSIVREYRKKFPRVSVALHELSTPDQVHALHDNRIDIGFL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHCCCCEEEEEC
RPPIPTQLLELEPIQKLSCTLCLPKAHPLAEKDEIHIEDLRDEPFVFITRPVWPALYDTI
CCCCCHHHHCCCCHHHHHHEEECCCCCCCCCCCCEEHCCCCCCCEEEEECCHHHHHHHHH
LSLCRDVGFSPRIVQEATEYQTVMGLVAAGIGITVIPVSANKLYKTEVVYKELYDSNFVA
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHCCCHHH
EMSVAYKKMNSNPELLEFLKIAREKKRIEVEDEIN
HHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685336; 9353933; 9384377 [H]