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The map label for this gene is dppE [H]

Identifier: 222097038

GI number: 222097038

Start: 3324381

End: 3326087

Strand: Reverse

Name: dppE [H]

Synonym: BCQ_3378

Alternate gene names: 222097038

Gene position: 3326087-3324381 (Counterclockwise)

Preceding gene: 222097039

Following gene: 222097037

Centisome position: 63.79

GC content: 35.09

Gene sequence:

>1707_bases
ATGAAGAAAAAGATGAAAAAGTTTACGTCGGTTGTAGCGCCAGTTTTAGCGATGAGTATGGCTTTAACAGCATGTTCTGG
ATCTTCTGGTGGGGAGAAAAAAACGACTACAACGTCTAATAATGGTGGGGAAGAGAAGAAATCTGATATTAAATATGCGG
CAAAGCAAGTGCTAAATCGTACAGAAACGAATGAAATTCCGACGATGGATACTTCCAAAAATACAGATACACTTGGATCA
CAAATTTTAGGAAATACAATGGAAGGTTTATATCGCTTGGATAAAGATAATAAGCCAATCCCAGCTGTAGCGGAATCTAG
CACAAAAAGCGAGGATGGCAAAAAATATACATTTAAATTACGGAAAGATGCAAAATGGTCAAATGGTGATCCTGTAACAG
CGAAAGATTTCGTATTTGCATGGCAACGTCTAGTAGATCCAAAAACAGCTGCTGAGTATGCATTTATTGCTTACTATCTT
AAAAATGCAGAAGCGATTAATCAAGGAAAAGGAGAAGTTTCGACATTAGGTGTAAAAGCGGTAGATGATTATACGCTTGA
AGTAGAACTAGAAAGACCAGTACCATATTTCTTGAACTTAATGGCATTTGCGTCATACTATCCATTAAATGAAAAGTTCG
TGAAAGAAAAAGGGAATAAATTTGGTTTAGAGTCTGATACAACACTTTATAATGGTCCATTTGTGCTTACTGATTGGAAG
CATGAGCAAGGCTGGAAATTAAAGAAAAATGAGCAGTATTGGGACAAAAAGACTGTGAAGCTAGAAGAAATCAATTATAG
TGTAGTAAAAGAACCAGCTACTAGAGTGAACTTATATGATACAGGTGCGATTGATTTCGCGCTTTTATCAGGTGAATTTG
TTGATAAGTATAGAAATAATAAAGAAGAATTTGGCGCATATTCGGAAACAAGTACGTTTTACTTACGTCTAAATCAAAAA
CGTGGTGGGCAAGATACACCGTTAAAGAGCAAAAAACTACGTGAAGCAATTGCATTATCAATTGATAAGAAAGCTTTAAC
GAATGTTATTTTAAATGATGGTTCAAAACCAGTGGATTATTTAGTAGCAAAAGGTTTGGCGAGTGGACCAGACGGTAAAG
ATTTCGCAGAAACGTTCAAGAATGGTTTAAAACAAGACTCCAAAAAGGCAGCGGCAGCTTGGGAAGAAGCGAAAAAAGAA
CTTGGAAAAGATCAAGTGACAATAGAGTTATTAAATTATGATACTGGTAATGCGAAAAAAGTTGGGGAGTATGTAAAAGA
TCAAGTTGAAAAGAATTTAAAAGGTGTGACAGTAAATATTAAGTTGCAACCATTTAAGCAAAAACTAAAATTAGAATCAG
ACCAAGATTATGATTTTTCATATGGTGGCTGGAATCCGGATTATGCGGATCCGATGACATATCTTGATATGTTTGAGACA
AAAAATTCGCAAAACCAGATGAGTTACTCAAATTCAAAATATGATGACATTATTAATAAAAGTAAGACGGAATGGATGGC
TGACGCAAAAAAACGTTGGGCAGAGTTAGGAAAGGCTGAAAAAATATTACTTGAAGATGATGTAGCGCTTGTACCTTTAT
ATCAAAATGCTAGATCATATGTTATGAAACCGAATGTAAAGGGAATTGTGAAACATAATATTAGTCCAGAATATAGTTTC
AAATGGGCGTATGTAGAAGAGAAATAG

Upstream 100 bases:

>100_bases
ATTAACAGGATGTTAATTAGTGAAAAGGTATTAATAACTAAGTTCATAGAAAAATCTCTCAAAGTTAGTTTCGTACATAT
AAATTGGGGAGGGTACAAAA

Downstream 100 bases:

>100_bases
TAAAAAAAGCATTTTCAAGTTGCGGTATGGCACTTGAAAATGCTTTTTTTCTGTGCACTATTTTTTTCAGGATGAATATA
TGTATTATAGAAAATTTAAA

Product: hypothetical protein

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 568; Mature: 568

Protein sequence:

>568_residues
MKKKMKKFTSVVAPVLAMSMALTACSGSSGGEKKTTTTSNNGGEEKKSDIKYAAKQVLNRTETNEIPTMDTSKNTDTLGS
QILGNTMEGLYRLDKDNKPIPAVAESSTKSEDGKKYTFKLRKDAKWSNGDPVTAKDFVFAWQRLVDPKTAAEYAFIAYYL
KNAEAINQGKGEVSTLGVKAVDDYTLEVELERPVPYFLNLMAFASYYPLNEKFVKEKGNKFGLESDTTLYNGPFVLTDWK
HEQGWKLKKNEQYWDKKTVKLEEINYSVVKEPATRVNLYDTGAIDFALLSGEFVDKYRNNKEEFGAYSETSTFYLRLNQK
RGGQDTPLKSKKLREAIALSIDKKALTNVILNDGSKPVDYLVAKGLASGPDGKDFAETFKNGLKQDSKKAAAAWEEAKKE
LGKDQVTIELLNYDTGNAKKVGEYVKDQVEKNLKGVTVNIKLQPFKQKLKLESDQDYDFSYGGWNPDYADPMTYLDMFET
KNSQNQMSYSNSKYDDIINKSKTEWMADAKKRWAELGKAEKILLEDDVALVPLYQNARSYVMKPNVKGIVKHNISPEYSF
KWAYVEEK

Sequences:

>Translated_568_residues
MKKKMKKFTSVVAPVLAMSMALTACSGSSGGEKKTTTTSNNGGEEKKSDIKYAAKQVLNRTETNEIPTMDTSKNTDTLGS
QILGNTMEGLYRLDKDNKPIPAVAESSTKSEDGKKYTFKLRKDAKWSNGDPVTAKDFVFAWQRLVDPKTAAEYAFIAYYL
KNAEAINQGKGEVSTLGVKAVDDYTLEVELERPVPYFLNLMAFASYYPLNEKFVKEKGNKFGLESDTTLYNGPFVLTDWK
HEQGWKLKKNEQYWDKKTVKLEEINYSVVKEPATRVNLYDTGAIDFALLSGEFVDKYRNNKEEFGAYSETSTFYLRLNQK
RGGQDTPLKSKKLREAIALSIDKKALTNVILNDGSKPVDYLVAKGLASGPDGKDFAETFKNGLKQDSKKAAAAWEEAKKE
LGKDQVTIELLNYDTGNAKKVGEYVKDQVEKNLKGVTVNIKLQPFKQKLKLESDQDYDFSYGGWNPDYADPMTYLDMFET
KNSQNQMSYSNSKYDDIINKSKTEWMADAKKRWAELGKAEKILLEDDVALVPLYQNARSYVMKPNVKGIVKHNISPEYSF
KWAYVEEK
>Mature_568_residues
MKKKMKKFTSVVAPVLAMSMALTACSGSSGGEKKTTTTSNNGGEEKKSDIKYAAKQVLNRTETNEIPTMDTSKNTDTLGS
QILGNTMEGLYRLDKDNKPIPAVAESSTKSEDGKKYTFKLRKDAKWSNGDPVTAKDFVFAWQRLVDPKTAAEYAFIAYYL
KNAEAINQGKGEVSTLGVKAVDDYTLEVELERPVPYFLNLMAFASYYPLNEKFVKEKGNKFGLESDTTLYNGPFVLTDWK
HEQGWKLKKNEQYWDKKTVKLEEINYSVVKEPATRVNLYDTGAIDFALLSGEFVDKYRNNKEEFGAYSETSTFYLRLNQK
RGGQDTPLKSKKLREAIALSIDKKALTNVILNDGSKPVDYLVAKGLASGPDGKDFAETFKNGLKQDSKKAAAAWEEAKKE
LGKDQVTIELLNYDTGNAKKVGEYVKDQVEKNLKGVTVNIKLQPFKQKLKLESDQDYDFSYGGWNPDYADPMTYLDMFET
KNSQNQMSYSNSKYDDIINKSKTEWMADAKKRWAELGKAEKILLEDDVALVPLYQNARSYVMKPNVKGIVKHNISPEYSF
KWAYVEEK

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the binding of dipeptides with high affinity. Is expressed to facilitate adaptation to nutrient deficiency conditions, which also induce sporulation [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787495, Length=511, Percent_Identity=31.8982387475538, Blast_Score=221, Evalue=9e-59,
Organism=Escherichia coli, GI87081878, Length=537, Percent_Identity=28.4916201117318, Blast_Score=213, Evalue=3e-56,
Organism=Escherichia coli, GI1789397, Length=507, Percent_Identity=28.2051282051282, Blast_Score=209, Evalue=4e-55,
Organism=Escherichia coli, GI1787762, Length=460, Percent_Identity=26.0869565217391, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1787052, Length=466, Percent_Identity=25.5364806866953, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1789887, Length=504, Percent_Identity=23.8095238095238, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1789966, Length=489, Percent_Identity=24.7443762781186, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: 760 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2360 Molecules/Cell In: Stationary-Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 64206; Mature: 64206

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKMKKFTSVVAPVLAMSMALTACSGSSGGEKKTTTTSNNGGEEKKSDIKYAAKQVLNR
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
TETNEIPTMDTSKNTDTLGSQILGNTMEGLYRLDKDNKPIPAVAESSTKSEDGKKYTFKL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCEEEEEE
RKDAKWSNGDPVTAKDFVFAWQRLVDPKTAAEYAFIAYYLKNAEAINQGKGEVSTLGVKA
ECCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHCCCCCEEEEEEEE
VDDYTLEVELERPVPYFLNLMAFASYYPLNEKFVKEKGNKFGLESDTTLYNGPFVLTDWK
ECCEEEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCEEECCCEEEECCC
HEQGWKLKKNEQYWDKKTVKLEEINYSVVKEPATRVNLYDTGAIDFALLSGEFVDKYRNN
CCCCCCCCCCCCHHCCCCEEEECCCHHHHCCCCCEEEEEECCCEEEEECCCHHHHHHCCC
KEEFGAYSETSTFYLRLNQKRGGQDTPLKSKKLREAIALSIDKKALTNVILNDGSKPVDY
HHHCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHH
LVAKGLASGPDGKDFAETFKNGLKQDSKKAAAAWEEAKKELGKDQVTIELLNYDTGNAKK
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHH
VGEYVKDQVEKNLKGVTVNIKLQPFKQKLKLESDQDYDFSYGGWNPDYADPMTYLDMFET
HHHHHHHHHHCCCCEEEEEEEECCHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHC
KNSQNQMSYSNSKYDDIINKSKTEWMADAKKRWAELGKAEKILLEDDVALVPLYQNARSY
CCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEECCEEEEEEHHCCCCE
VMKPNVKGIVKHNISPEYSFKWAYVEEK
EECCCCCCCEECCCCCCCEEEEEEEECC
>Mature Secondary Structure
MKKKMKKFTSVVAPVLAMSMALTACSGSSGGEKKTTTTSNNGGEEKKSDIKYAAKQVLNR
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
TETNEIPTMDTSKNTDTLGSQILGNTMEGLYRLDKDNKPIPAVAESSTKSEDGKKYTFKL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCEEEEEE
RKDAKWSNGDPVTAKDFVFAWQRLVDPKTAAEYAFIAYYLKNAEAINQGKGEVSTLGVKA
ECCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHCCCCCEEEEEEEE
VDDYTLEVELERPVPYFLNLMAFASYYPLNEKFVKEKGNKFGLESDTTLYNGPFVLTDWK
ECCEEEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCEEECCCEEEECCC
HEQGWKLKKNEQYWDKKTVKLEEINYSVVKEPATRVNLYDTGAIDFALLSGEFVDKYRNN
CCCCCCCCCCCCHHCCCCEEEECCCHHHHCCCCCEEEEEECCCEEEEECCCHHHHHHCCC
KEEFGAYSETSTFYLRLNQKRGGQDTPLKSKKLREAIALSIDKKALTNVILNDGSKPVDY
HHHCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHH
LVAKGLASGPDGKDFAETFKNGLKQDSKKAAAAWEEAKKELGKDQVTIELLNYDTGNAKK
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHH
VGEYVKDQVEKNLKGVTVNIKLQPFKQKLKLESDQDYDFSYGGWNPDYADPMTYLDMFET
HHHHHHHHHHCCCCEEEEEEEECCHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHC
KNSQNQMSYSNSKYDDIINKSKTEWMADAKKRWAELGKAEKILLEDDVALVPLYQNARSY
CCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEECCEEEEEEHHCCCCE
VMKPNVKGIVKHNISPEYSFKWAYVEEK
EECCCCCCCEECCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377 [H]