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The map label for this gene is moaE [H]

Identifier: 222097019

GI number: 222097019

Start: 3302389

End: 3302853

Strand: Reverse

Name: moaE [H]

Synonym: BCQ_3359

Alternate gene names: 222097019

Gene position: 3302853-3302389 (Counterclockwise)

Preceding gene: 222097020

Following gene: 222097018

Centisome position: 63.34

GC content: 38.92

Gene sequence:

>465_bases
ATGGGACAAGTGCTATTTGAGATTGTTGATATACCGATTGTAGTTGAAGAAGTAACGAATAAAGTTGCAAGAAGAGAGGC
AGGTGCGATTACAACTTTTATTGGTACAGTGAGAGAATTAACAAAAGGAAGACGAACGCTATATTTAGAGTATGAAGCAT
ATGAAACGATGGCAGTAAAACAACTTATGAGAATTGGTGAAGAAATTAGTGAAAGATGGCCGGATGCAAAAGTAGCAATT
ACTCACCGAGTAGGCCGGCTAGAAATAATGGATATTGCGGTAGTCATTGCAGTTTCATCACCGCATCGTAAAGTAGCTTA
TGAAGCGAATGAATACGCAATTGAACGTATAAAGCGAATCGTCCCAATATGGAAAAAAGAATTTTGGGAAGATGGGACGA
TGTGGATTGGCGATCAACTTGAAAATACACCATATCCAGCAGGAAAACCGAAGAAGGAAGAATGA

Upstream 100 bases:

>100_bases
AGAGGGTATAAAAAAGATATGTTCGTAGATGTTCTCTTGTTGGAAGATAACGAAGGTAGTGAATGGCCTTGGACATTTTA
TAAAGTGAGAGGTGATTCTA

Downstream 100 bases:

>100_bases
GAAAATGATTACAATTTTACTGTTTGCAAATTTGCGTGAGGAAGTCGGATTAGATCGATTCGTAATTTCAGAAAAACAAG
AAATGACAGTGCAGCAATTA

Product: molybdopterin converting factor, subunit 2

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 154; Mature: 153

Protein sequence:

>154_residues
MGQVLFEIVDIPIVVEEVTNKVARREAGAITTFIGTVRELTKGRRTLYLEYEAYETMAVKQLMRIGEEISERWPDAKVAI
THRVGRLEIMDIAVVIAVSSPHRKVAYEANEYAIERIKRIVPIWKKEFWEDGTMWIGDQLENTPYPAGKPKKEE

Sequences:

>Translated_154_residues
MGQVLFEIVDIPIVVEEVTNKVARREAGAITTFIGTVRELTKGRRTLYLEYEAYETMAVKQLMRIGEEISERWPDAKVAI
THRVGRLEIMDIAVVIAVSSPHRKVAYEANEYAIERIKRIVPIWKKEFWEDGTMWIGDQLENTPYPAGKPKKEE
>Mature_153_residues
GQVLFEIVDIPIVVEEVTNKVARREAGAITTFIGTVRELTKGRRTLYLEYEAYETMAVKQLMRIGEEISERWPDAKVAIT
HRVGRLEIMDIAVVIAVSSPHRKVAYEANEYAIERIKRIVPIWKKEFWEDGTMWIGDQLENTPYPAGKPKKEE

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=127, Percent_Identity=40.1574803149606, Blast_Score=111, Evalue=2e-25,
Organism=Escherichia coli, GI1787003, Length=123, Percent_Identity=36.5853658536585, Blast_Score=81, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17509279, Length=127, Percent_Identity=38.5826771653543, Blast_Score=94, Evalue=3e-20,
Organism=Drosophila melanogaster, GI21356259, Length=125, Percent_Identity=39.2, Blast_Score=106, Evalue=5e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 17762; Mature: 17631

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQVLFEIVDIPIVVEEVTNKVARREAGAITTFIGTVRELTKGRRTLYLEYEAYETMAVK
CCHHHHHHHCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHH
QLMRIGEEISERWPDAKVAITHRVGRLEIMDIAVVIAVSSPHRKVAYEANEYAIERIKRI
HHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEEEEEEECCCCCEEEECHHHHHHHHHHHH
VPIWKKEFWEDGTMWIGDQLENTPYPAGKPKKEE
HHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GQVLFEIVDIPIVVEEVTNKVARREAGAITTFIGTVRELTKGRRTLYLEYEAYETMAVK
CHHHHHHHCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHH
QLMRIGEEISERWPDAKVAITHRVGRLEIMDIAVVIAVSSPHRKVAYEANEYAIERIKRI
HHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEEEEEEECCCCCEEEECHHHHHHHHHHHH
VPIWKKEFWEDGTMWIGDQLENTPYPAGKPKKEE
HHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]