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The map label for this gene is mrp [H]

Identifier: 222097017

GI number: 222097017

Start: 3301032

End: 3302000

Strand: Reverse

Name: mrp [H]

Synonym: BCQ_3357

Alternate gene names: 222097017

Gene position: 3302000-3301032 (Counterclockwise)

Preceding gene: 222097018

Following gene: 222097016

Centisome position: 63.33

GC content: 37.05

Gene sequence:

>969_bases
ATGGTTAGAAATATACAAATGAATGGAACAGAGGTTAAACTTGAAGTAGTGCTAACGATTCAAGGGTGTCCGTTAAAATC
AAAAATTCAACAAGATATTGAAGAATCGCTTCACGCAATTGGTGCCTCTAAAGTGGCTGTAACATTTAGTTCTATGACAA
AAGAAGAACGTGCAGTCTTAACAGAGAAGTTAAAGAAAAATACTAGAACAGAAACTGGTATGCCAAGCATGCTTCGTCCT
GATTCAGGAGTACAATTTCTTACTGTAACGAGCGGAAAAGGTGGAGTCGGAAAATCAACTGTAACAATTAATCTTGCAAC
AGCTTTAGCTCGTATGGGCAAAAAAGTGGGGATATTAGATGCAGATATATATGGTTTTAGCATTCCAGCTATGATGGAAA
CGAATCAAAAACCAACGATGATTGATCAAACAGCAATTCCAGTTATTAGTCACGGTGTTAAAATTATGTCTATGGGATTT
TTTACAGAAGGAAATAATCCGGTTATGTGGCGCGGACCGATGTTAAATAAATGGATTCAAAATTTCCTTGCGAATACGCA
CTGGGGAGAATTAGATTATTTACTTCTTGATTTACCACCTGGTACAGGAGATGTTGCTATTGATGTTGCAGCAATGATTC
CGCAGGCGAAAGAAATTATTGTTACAACACCACATAATGTAGCTTCATTCGTAGCATCTAGAGTAGGCGTAATGGCAAAA
CATACGAAACACGAGATTTTAGGTATTGTGGAAAACATGGCTTATTATGAAGAACAAGATGGATCGAAAAATTATCTGTT
CGGAAAAGGCGGCGGGGAAATGTTAGCAGAACAATTGCAAACAGAAGTAATCGCACAAGTACCTTTTGCAAAACGTGAAG
AAAATAGCGGTTCATCTGTATATGATGAAGATTCTCTTGTTGGAGAAGTGTTTACATCGTTAGCAGAAGATATTATTTAT
AAAGGATAG

Upstream 100 bases:

>100_bases
ACGAGAAGGGATGAGTTCTATGCTTACTCAAGAACAAATAATGAATGCGTTAAAACATGTAGAGGATCCAGAATTACACA
AAAGTATTGTGGAGTTAAAC

Downstream 100 bases:

>100_bases
AGGAGGAATTTTTTATGGCATGTAATATCGATCATTCTATTGAAGATGTAATGAATAAGCTCGAGAGCCAAAAGAGTTTT
TTACCGGAAGTGATTTTTAA

Product: ATP-binding mrp protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MVRNIQMNGTEVKLEVVLTIQGCPLKSKIQQDIEESLHAIGASKVAVTFSSMTKEERAVLTEKLKKNTRTETGMPSMLRP
DSGVQFLTVTSGKGGVGKSTVTINLATALARMGKKVGILDADIYGFSIPAMMETNQKPTMIDQTAIPVISHGVKIMSMGF
FTEGNNPVMWRGPMLNKWIQNFLANTHWGELDYLLLDLPPGTGDVAIDVAAMIPQAKEIIVTTPHNVASFVASRVGVMAK
HTKHEILGIVENMAYYEEQDGSKNYLFGKGGGEMLAEQLQTEVIAQVPFAKREENSGSSVYDEDSLVGEVFTSLAEDIIY
KG

Sequences:

>Translated_322_residues
MVRNIQMNGTEVKLEVVLTIQGCPLKSKIQQDIEESLHAIGASKVAVTFSSMTKEERAVLTEKLKKNTRTETGMPSMLRP
DSGVQFLTVTSGKGGVGKSTVTINLATALARMGKKVGILDADIYGFSIPAMMETNQKPTMIDQTAIPVISHGVKIMSMGF
FTEGNNPVMWRGPMLNKWIQNFLANTHWGELDYLLLDLPPGTGDVAIDVAAMIPQAKEIIVTTPHNVASFVASRVGVMAK
HTKHEILGIVENMAYYEEQDGSKNYLFGKGGGEMLAEQLQTEVIAQVPFAKREENSGSSVYDEDSLVGEVFTSLAEDIIY
KG
>Mature_322_residues
MVRNIQMNGTEVKLEVVLTIQGCPLKSKIQQDIEESLHAIGASKVAVTFSSMTKEERAVLTEKLKKNTRTETGMPSMLRP
DSGVQFLTVTSGKGGVGKSTVTINLATALARMGKKVGILDADIYGFSIPAMMETNQKPTMIDQTAIPVISHGVKIMSMGF
FTEGNNPVMWRGPMLNKWIQNFLANTHWGELDYLLLDLPPGTGDVAIDVAAMIPQAKEIIVTTPHNVASFVASRVGVMAK
HTKHEILGIVENMAYYEEQDGSKNYLFGKGGGEMLAEQLQTEVIAQVPFAKREENSGSSVYDEDSLVGEVFTSLAEDIIY
KG

Specific function: Negatively regulates the expression of hpr/scoC. The effect on hpr/scoC may be indirect [H]

COG id: COG0489

COG function: function code D; ATPases involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mrp/NBP35 ATP-binding proteins family [H]

Homologues:

Organism=Homo sapiens, GI157384956, Length=234, Percent_Identity=39.3162393162393, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI6912540, Length=214, Percent_Identity=38.3177570093458, Blast_Score=135, Evalue=4e-32,
Organism=Homo sapiens, GI118572611, Length=215, Percent_Identity=33.953488372093, Blast_Score=114, Evalue=1e-25,
Organism=Escherichia coli, GI87082045, Length=207, Percent_Identity=46.3768115942029, Blast_Score=176, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI25143050, Length=252, Percent_Identity=37.3015873015873, Blast_Score=130, Evalue=8e-31,
Organism=Saccharomyces cerevisiae, GI6322188, Length=244, Percent_Identity=36.8852459016393, Blast_Score=137, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6321347, Length=222, Percent_Identity=33.3333333333333, Blast_Score=103, Evalue=4e-23,
Organism=Drosophila melanogaster, GI221511043, Length=253, Percent_Identity=39.5256916996047, Blast_Score=164, Evalue=6e-41,
Organism=Drosophila melanogaster, GI24667611, Length=246, Percent_Identity=37.8048780487805, Blast_Score=138, Evalue=6e-33,
Organism=Drosophila melanogaster, GI19921440, Length=222, Percent_Identity=33.3333333333333, Blast_Score=90, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019591
- InterPro:   IPR000808 [H]

Pfam domain/function: PF10609 ParA [H]

EC number: NA

Molecular weight: Translated: 35089; Mature: 35089

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS01215 MRP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRNIQMNGTEVKLEVVLTIQGCPLKSKIQQDIEESLHAIGASKVAVTFSSMTKEERAVL
CCEEEECCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHH
TEKLKKNTRTETGMPSMLRPDSGVQFLTVTSGKGGVGKSTVTINLATALARMGKKVGILD
HHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEEHHHHHHHCCCCCCEEE
ADIYGFSIPAMMETNQKPTMIDQTAIPVISHGVKIMSMGFFTEGNNPVMWRGPMLNKWIQ
CCCCCEECCHHHCCCCCCCEECHHHHHHHHCCEEEEEEEEEECCCCEEEEECHHHHHHHH
NFLANTHWGELDYLLLDLPPGTGDVAIDVAAMIPQAKEIIVTTPHNVASFVASRVGVMAK
HHHCCCCCCCEEEEEEECCCCCCCCEEEHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHH
HTKHEILGIVENMAYYEEQDGSKNYLFGKGGGEMLAEQLQTEVIAQVPFAKREENSGSSV
HHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
YDEDSLVGEVFTSLAEDIIYKG
CCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVRNIQMNGTEVKLEVVLTIQGCPLKSKIQQDIEESLHAIGASKVAVTFSSMTKEERAVL
CCEEEECCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHH
TEKLKKNTRTETGMPSMLRPDSGVQFLTVTSGKGGVGKSTVTINLATALARMGKKVGILD
HHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEEHHHHHHHCCCCCCEEE
ADIYGFSIPAMMETNQKPTMIDQTAIPVISHGVKIMSMGFFTEGNNPVMWRGPMLNKWIQ
CCCCCEECCHHHCCCCCCCEECHHHHHHHHCCEEEEEEEEEECCCCEEEEECHHHHHHHH
NFLANTHWGELDYLLLDLPPGTGDVAIDVAAMIPQAKEIIVTTPHNVASFVASRVGVMAK
HHHCCCCCCCEEEEEEECCCCCCCCEEEHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHH
HTKHEILGIVENMAYYEEQDGSKNYLFGKGGGEMLAEQLQTEVIAQVPFAKREENSGSSV
HHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
YDEDSLVGEVFTSLAEDIIYKG
CCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7559346; 8969501; 9384377; 2517635 [H]